Caio Maximino


Affiliation: Universidade Federal do Par
Country: Brazil


  1. Maximino C, da Silva A, Gouveia A, Herculano A. Pharmacological analysis of zebrafish (Danio rerio) scototaxis. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:624-31 pubmed publisher
    ..5% concentration. Caffeine produced an anxiogenic profile, without locomotor effects. These results suggest that the light-dark box is sensitive to anxiolytic and anxiogenic drugs in zebrafish. ..
  2. Maximino C, de Brito T, da Silva Batista A, Herculano A, Morato S, Gouveia A. Measuring anxiety in zebrafish: a critical review. Behav Brain Res. 2010;214:157-71 pubmed publisher
    ..The refinement of models is an ongoing activity, and behavioral validation and parametric research ought to advance that objective. ..
  3. Maximino C, Marques de Brito T, Dias C, Gouveia A, Morato S. Scototaxis as anxiety-like behavior in fish. Nat Protoc. 2010;5:209-16 pubmed publisher
    ..When individual animals are exposed to the apparatus on only one occasion, results can be obtained in 20 min per fish...
  4. Maximino C, Lima M, Olivera K, Picanço Diniz D, Herculano A. Adenosine A1, but not A2, receptor blockade increases anxiety and arousal in Zebrafish. Basic Clin Pharmacol Toxicol. 2011;109:203-7 pubmed publisher
    ..Thus, as in rodents, caffeine's anxiogenic and arousing effects are probably mediated by A(1) receptors in zebrafish and its locomotor activating effect is probably mediated by A(2) receptors. ..
  5. Maximino C, Puty B, Benzecry R, Araújo J, Lima M, de Jesus Oliveira Batista E, et al. Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models. Neuropharmacology. 2013;71:83-97 pubmed publisher
    ..These results underline the differential sensitivity of these tasks to assess serotonergic agents; alternatively, serotonin might regulate zebrafish behavior differently in the novel tank test and in the light/dark test...