Valdirene M Gomes


Affiliation: Universidade Estadual do Norte Fluminense
Country: Brazil


  1. Maracahipes Á, Taveira G, Mello E, Carvalho A, Rodrigues R, Perales J, et al. Biochemical analysis of antimicrobial peptides in two different Capsicum genotypes after fruit infection by Colletotrichum gloeosporioides. Biosci Rep. 2019;39: pubmed publisher
    ..It was shown that the green fruits are more responsive to infection, showing the production of antimicrobial peptides in response to injury and inoculation of the fungus, what did not occur in ripe fruits under any treatment. ..
  2. Pinedo M, Orts F, Carvalho A, Regente M, Soares J, Gomes V, et al. Molecular characterization of Helja, an extracellular jacalin-related protein from Helianthus annuus: Insights into the relationship of this protein with unconventionally secreted lectins. J Plant Physiol. 2015;183:144-53 pubmed publisher
    ..Because the recovered JRLs are widely distributed among the plant kingdom, an as yet unknown role for jacalin lectins in the apoplast is emerging. ..
  3. do Nascimento V, Mello Ã, Carvalho L, de Melo E, Carvalho A, Fernandes K, et al. PvD1 defensin, a plant antimicrobial peptide with inhibitory activity against Leishmania amazonensis. Biosci Rep. 2015;35: pubmed publisher
    ..Furthermore, we show, for the first time, that PvD1 defensin was located within the L. amazonensis cells, suggesting the existence of a possible intracellular target. ..
  4. Taveira G, Mello E, Souza S, Monteiro R, Ramos A, Carvalho A, et al. Programmed cell death in yeast by thionin-like peptide from Capsicum annuum fruits involving activation of caspases and extracellular H+ flux. Biosci Rep. 2018;38: pubmed publisher
    ..In conclusion, our results strongly indicated that CaThi triggers apoptosis in C. tropicalis cells, involving a pH signaling mechanism. ..
  5. Taveira G, Carvalho A, Rodrigues R, Trindade F, DA Cunha M, Gomes V. Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species. BMC Microbiol. 2016;16:12 pubmed publisher
    ..0 times below CaThi IC50 and from zero to 2.0 times below fluconazole IC50. The results reported herein may ultimately contribute to future efforts aiming to employ this plant-derived AMP as a new therapeutic substance against yeasts. ..
  6. Pinedo M, Genoula M, Silveyra M, de Oliveira Carvalho A, Regente M, Del Río M, et al. Anti-Neuroblastoma Properties of a Recombinant Sunflower Lectin. Int J Mol Sci. 2017;18: pubmed publisher
    ..Our results indicate that rHelja is a promising tool for the development of diagnostic or therapeutic methods for neuroblastoma cells, the most common solid tumors in childhood. ..
  7. Mello E, Dos Santos I, Carvalho A, de Souza L, de Souza Filho G, do Nascimento V, et al. Functional expression and activity of the recombinant antifungal defensin PvD1r from Phaseolus vulgaris L. (common bean) seeds. BMC Biochem. 2014;15:7 pubmed publisher
    ..albicans cells is the sphingolipid glucosylceramide. ..
  8. Dos Santos L, Taveira G, Ribeiro S, Pereira L, Carvalho A, Rodrigues R, et al. Purification and characterization of peptides from Capsicum annuum fruits which are α-amylase inhibitors and exhibit high antimicrobial activity against fungi of agronomic importance. Protein Expr Purif. 2017;132:97-107 pubmed publisher
    ..Fungi belonging to the genus Fusarium also showed an increase in the endogenous production of ROS when treated with this fraction. Antimicrobial peptides were also identified in the fruits from other Capsicum species. ..