Research Topics
Species | Lilian CastilhoSummaryAffiliation: Universidade Estadual de Campinas Country: Brazil Publications
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Detail Information
Publications
Duffy blood group gene polymorphisms among malaria vivax patients in four areas of the Brazilian Amazon regionCarlos E Cavasini
Centro de Investigação de Microrganismos, Faculdade de Medicina de Sao Jose do Rio Preto, Av, Brigadeiro Faria Lima, 5416, Sao Jose do Rio Preto, São Paulo State 15090 000, Brazil
Malar J 6:167. 2007..vivax malaria patients from four different Brazilian endemic areas is reported, exploring significant associations between blood group variants and susceptibility or resistance to malaria...
DNA-based typing of blood groups for the management of multiply-transfused sickle cell disease patientsLilian Castilho
Hematology and Hemotherapy Center, State University of Campinas UNICAMP, Campinas, SP, Brazil
Transfusion 42:232-8. 2002..The usefulness of DNA genotyping for RBC antigens as a tool for the management of multiply-transfused patients with sickle cell disease (SCD) to overcome the limitations of hemagglutination assays was evaluated...
The value of DNA analysis for antigens in the Duffy blood group systemLilian Castilho
Hemocentro, UNICAMP, Campinas, Rua Carlos Chagas 480, , Campinas, , Brazil
Transfusion 47:28S-31S. 2007
Blood group genotyping facilitates transfusion of beta-thalassemia patientsLilian Castilho
Hemocentro Unicamp, Campinas, SP, Brasil
J Clin Lab Anal 16:216-20. 2002....
Weakened expression of 'e' owing to concomitant occurrence of Cys16 and Val245 (VS antigen)A Rodrigues
Hemocentro da UNICAMP, SP, Brazil
Vox Sang 86:136-40. 2004..This study investigated the association of Cys16 and/or VS with the RHCE ce alleles in a cohort of sickle cell disease (SCD) patients phenotyped as R(0)r or R(0)R(0) and rr...
A novel FY allele in BraziliansL Castilho
Hemocentro, UNICAMP, Campinas, Sao Paulo, Brazil
Vox Sang 87:190-5. 2004..These findings highlight the importance of establishing the incidence and nature of molecular events that impact on Duffy expression in different populations...
High frequency of partial DIIIa and DAR alleles found in sickle cell disease patients suggests increased risk of alloimmunization to RhDL Castilho
Hemocentro Unicamp, Campinas, SP, Brazil
Transfus Med 15:49-55. 2005..Three patients were anti-D immunized (DAR, n = 1; DIIIa/DAR, n = 2). These findings suggest that SCD patients who are candidates for chronic transfusion may benefit from genotyping for DIIIa and DAR to prevent alloimmunization...
A novel DI*A allele without the Band 3-Memphis mutation in Amazonian IndiansW Baleotti
Hemocentro, Faculdade de Medicina, , Sao Paulo, Brazil
Vox Sang 84:326-30. 2003..CONCLUSIONS: Our results revealed that DI*A does not have a strict association with 166G. They also show the relevance of testing a cohort of different populations...
Blood group genotyping in a population of highly diverse ancestryJ Pellegrino
Hemocentro Unicamp, Campinas, SP, Brazil
J Clin Lab Anal 15:8-13. 2001..Essentially, 30.5 % of the donors with the FY B gene typed as Fy(b-) because of mutations in the GATA box. This information is very useful for the management of transfusion dependent patients...
Fetal rhd genotyping from maternal plasma in a population with a highly diverse ethnic backgroundIsabela Nelly Machado
Departamento de Tocoginecologia da Universidade Estadual de Campinas e Hemocentro Unicamp, Universidade Estadual de Campinas, Campinas, SP
Rev Assoc Med Bras 52:232-5. 2006..To establish the performance of conventional PCR as a noninvasive method for fetal genotyping, by free fetal DNA analysis of distinct RHD regions from maternal plasma, in a population of a diverse ethnic origin...
Serologic and molecular characterization of D variants in Brazilians: impact for typing and transfusion strategyDébora Castilho Credidio
Instituto Nacional de Ciência e Tecnologia do Sangue, Hemocentro, UNICAMP, Rua Carlos Chagas, 480, Caixa Postal 6198, CEP 13081 970 Barão Geraldo, Campinas, SP, Brazil
Immunohematology 27:6-11. 2011..This distinction is important for optimized management of D– RBC units and for the prevention of anti-D–related hemolytic disease of the fetus and newborn...
Fetal RHD genotyping by analysis of maternal plasma in a mixed populationDaphne R T Amaral
Hemocentro, UNICAMP, Campinas, Sao Paulo, Brazil
J Clin Lab Anal 25:100-4. 2011..We assessed the accuracy of fetal RHD genotyping by analysis of maternal plasma in a multi-ethnic population...
A PCR-based strategy for Dombrock screening in Brazilian blood donors reveals a novel allele: the DO* A-WLWilson Baleotti
Hemocentro, Faculdade de Medicina, Marilia, Sao Paulo, Brazil
J Clin Lab Anal 25:79-82. 2011..Based on this, we employed a PCR-based strategy to screen DO alleles (DO(*) A, DO(*) B, HY(*) 1, HY(*) 2 and JO) in Brazilians...
Presence of the RHD pseudogene and the hybrid RHD-CE-D(s) gene in Brazilians with the D-negative phenotypeA Rodrigues
Hemocentro, Universidade Estadual de Campinas, Campinas, SP, Brasil
Braz J Med Biol Res 35:767-73. 2002..These data confirm that the inclusion of two different multiplex PCR for RHD is essential to test the D-negative Brazilian population in order to avoid false-positive typing of polytransfused patients and fetuses...
Twelve years of the Brazilian External Quality Assessment Program in Immunohematology: benefits of the programLaércio Melo
Hemocentro da UNICAMP, Sao Paulo, Brazil
J Clin Lab Anal 19:209-18. 2005..We found that a well-organized external proficiency program can contribute to the improvement of quality of testing in Immunohematology...
Frequencies of ABO, MNSs, and Duffy phenotypes among blood donors and malaria patients from four Brazilian Amazon areasCarlos Eugênio Cavasini
Center for Microorganisms Investigation, Department of Dermatological, Infectious, and Parasitical Diseases, Faculty of Medicine of São José do Rio Preto, Av Brigadeiro Faria Lima 5416, São José do Rio Preto 15090 000, Sao Paulo, Brazil
Hum Biol 78:215-9. 2006..Some of the Duffy phenotypes showed significant correlation between donors and malaria patients in different areas. These data are an additional contribution to the establishment of differential host susceptibility to malaria...
DNA array analysis for red blood cell antigens facilitates the transfusion support with antigen-matched blood in patients with sickle cell diseaseK R Ribeiro
Hemocentro Unicamp, Rua Carlos Chagas 480, Campinas, Sao Paulo, Brazil
Vox Sang 97:147-52. 2009..To overcome this problem we developed an effective strategy to meet needs of supplying RBC-compatible units to SCD patients using DNA arrays...
Dombrock gene analysis in Brazilian people reveals novel allelesW Baleotti
Hemocentro, Faculdade de Medicina, , SP, Brazil
Vox Sang 91:81-7. 2006..Our study also highlights the importance of testing a cohort of different populations to determine DO haplotypes and of establishing reliable genotyping tests for predicting Doa/Dob status...
Anti-D alloimmunization by weak D type 1 red blood cells with a very low antigen densityM Mota
Departamento de Hemoterapia, Hospital Israelita Albert Einstein, SP, Brazil
Vox Sang 88:130-5. 2005
DARC (Duffy) and BCAM (Lutheran) reduced expression in thyroid cancerFlávia Roche Moreira Latini
Colsan Associação Beneficente de Coleta de Sangue, Avenida Jandira 1260, Indianopolis, Sao Paulo, SP, CEP 04080 006, Brazil Electronic address
Blood Cells Mol Dis 50:161-5. 2013..We, also, found a correlation between decreased BCAM expression and tumor size or presence of metastasis. DARC and BCAM expression was associated with pathogenesis of thyroid carcinoma and correlated with clinical-pathological features...
Rhnull syndrome: identification of a novel mutation in RHceK A Rosa
Hemocentro Unicamp, Campinas, SP, Brazil
Transfusion 45:1796-8. 2005..A novel mutation resulting in the amorph Rh(null) with loss of Rh antigen expression is described...
Identification of six new alleles at the FUT1 and FUT2 loci in ethnically diverse individuals with Bombay and Para-Bombay phenotypesJill R Storry
Blood Center, Lund University Hospital and Department of Hematology and Transfusion Medicine, Lund University, Lund, Sweden
Transfusion 46:2149-55. 2006..Samples from seven individuals of different geographic backgrounds whose red blood cells had an apparent Bombay or para-Bombay phenotype were investigated. Among these, novel FUT1 and FUT2 alleles were identified...
Analysis in non-human primates reveals that the ancestral Band 3 gene encodes Dib and the Band 3-Memphis phenotypeAlissa Schawalder
Immunohematology and Immunochemisry Laboratories, New York Blood Center, New York, NY 10021, USA
J Med Primatol 35:144-8. 2006..CONCLUSIONS: The nonhuman primates have nucleotide sequences of Di(b)(2561C) in cis to Band 3-Memphis (166G), which is consistent with the assertion that the Di(b) and Band 3-Memphis phenotype represents the ancestral Band 3 gene...
Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?Carlos Eugênio Cavasini
Faculty of Medicine, Sao Jose do Rio Preto, Av Brigadeiro Faria Lima 5416, 15090 000 Sao Jose do Rio Preto, Sao Paulo State, Brazil
Trans R Soc Trop Med Hyg 101:1042-4. 2007..vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region...
