Tatiana Barichello

Summary

Affiliation: Universidade do Extremo Sul Catarinense
Country: Brazil

Publications

  1. ncbi request reprint Brain creatine kinase activity after meningitis induced by Streptococcus pneumoniae
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res Bull 80:85-8. 2009
  2. ncbi request reprint Neonatal Escherichia coli K1 meningitis causes learning and memory impairments in adulthood
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Center for Experimental Models in Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, TX, USA Electronic address
    J Neuroimmunol 272:35-41. 2014
  3. ncbi request reprint Erythropoietin prevents cognitive impairment and oxidative parameters in Wistar rats subjected to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Center for Experimental Models in Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, TX, USA Electronic address
    Transl Res 163:503-13. 2014
  4. ncbi request reprint Inhibition of indoleamine 2,3-dioxygenase prevented cognitive impairment in adult Wistar rats subjected to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Instituto Nacional de Ciência e Tecnologia Translacional em Medicina INCT TM, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Núcleo de Excelência em Neurociências Aplicadas de Santa Catarina NENASC, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Electronic address
    Transl Res 162:390-7. 2013
  5. pmc Role of oxidative stress in the pathophysiology of pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Oxid Med Cell Longev 2013:371465. 2013
  6. ncbi request reprint Pathophysiology of bacterial infection of the central nervous system and its putative role in the pathogenesis of behavioral changes
    Tatiana Barichello
    Laboratory of Experimental Microbiology, Universidade do Extremo Sul Catarinense, Brazil
    Rev Bras Psiquiatr 35:81-7. 2013
  7. pmc Attenuation of cognitive impairment by the nonbacteriolytic antibiotic daptomycin in Wistar rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    BMC Neurosci 14:42. 2013
  8. doi request reprint Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae
    Tatiana Barichello
    Laboratório de Microbiologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res Bull 92:56-9. 2013
  9. pmc Dexamethasone treatment reverses cognitive impairment but increases brain oxidative stress in rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000 Criciuma, SC, Brazil
    Oxid Med Cell Longev 2011:173035. 2011
  10. doi request reprint Acetylcholinesterase activity in the rat brain after pneumococcal meningitis
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute of Science and Translacional Technology in Medicine, 88806 000 Criciuma, SC, Brazil
    Microbiol Immunol 56:191-4. 2012

Detail Information

Publications46

  1. ncbi request reprint Brain creatine kinase activity after meningitis induced by Streptococcus pneumoniae
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res Bull 80:85-8. 2009
    ..Finally, CK activity was not altered 48h after meningitis. Although it is difficult to extrapolate our findings to the human condition, the inhibition of brain CK activity may be involved in the pathogenesis of pneumococcal meningitis...
  2. ncbi request reprint Neonatal Escherichia coli K1 meningitis causes learning and memory impairments in adulthood
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Center for Experimental Models in Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, TX, USA Electronic address
    J Neuroimmunol 272:35-41. 2014
    ..In adulthood, the animals showed habituation and aversive memory impairment. The animals needed a significant increase in the number of training periods to learn and not had depressive-like symptoms. ..
  3. ncbi request reprint Erythropoietin prevents cognitive impairment and oxidative parameters in Wistar rats subjected to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Center for Experimental Models in Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, TX, USA Electronic address
    Transl Res 163:503-13. 2014
    ..Although there are some limitations with respect to the animal model of pneumococcal meningitis, this study suggests that adjuvant treatment with EPO contributed to decreased oxidative stress and prevented cognitive impairment. ..
  4. ncbi request reprint Inhibition of indoleamine 2,3-dioxygenase prevented cognitive impairment in adult Wistar rats subjected to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Instituto Nacional de Ciência e Tecnologia Translacional em Medicina INCT TM, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Núcleo de Excelência em Neurociências Aplicadas de Santa Catarina NENASC, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil Electronic address
    Transl Res 162:390-7. 2013
    ....
  5. pmc Role of oxidative stress in the pathophysiology of pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Oxid Med Cell Longev 2013:371465. 2013
    ..This formation generates oxidative and nitrosative stress, subsequently, lipid peroxidation, mitochondrial damage, and BBB breakdown, which contributes to cell injury during pneumococcal meningitis...
  6. ncbi request reprint Pathophysiology of bacterial infection of the central nervous system and its putative role in the pathogenesis of behavioral changes
    Tatiana Barichello
    Laboratory of Experimental Microbiology, Universidade do Extremo Sul Catarinense, Brazil
    Rev Bras Psiquiatr 35:81-7. 2013
    ..The aim of this review is to summarize the current knowledge of the relevant pathophysiologic steps in CNS infections...
  7. pmc Attenuation of cognitive impairment by the nonbacteriolytic antibiotic daptomycin in Wistar rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    BMC Neurosci 14:42. 2013
    ..The aim of the present study was to evaluate the effects of the nonbacteriolytic antibiotic daptomycin versus ceftriaxone on behavioral parameters in adult Wistar rats submitted to pneumococcal meningitis...
  8. doi request reprint Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae
    Tatiana Barichello
    Laboratório de Microbiologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res Bull 92:56-9. 2013
    ..These findings suggest that the meningitis model could be a good research tool for the study of the biological mechanisms involved in the behavioral alterations secondary to GBS meningitis...
  9. pmc Dexamethasone treatment reverses cognitive impairment but increases brain oxidative stress in rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000 Criciuma, SC, Brazil
    Oxid Med Cell Longev 2011:173035. 2011
    ..2 mg/kg/7 days. Our findings demonstrate that dexamethasone reverted cognitive impairment but increased brain oxidative stress in hippocampus and cortex in Wistar rats ten days after pneumococcal meningitis induction...
  10. doi request reprint Acetylcholinesterase activity in the rat brain after pneumococcal meningitis
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute of Science and Translacional Technology in Medicine, 88806 000 Criciuma, SC, Brazil
    Microbiol Immunol 56:191-4. 2012
    ..Our data suggest that acetylcholinesterase activity could be related to neuronal damage induced by pneumococcal meningitis...
  11. doi request reprint Brain-blood barrier breakdown and pro-inflammatory mediators in neonate rats submitted meningitis by Streptococcus pneumoniae
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res 1471:162-8. 2012
    ..The time-dependent association between the complex interactions among cytokines, chemokine may be responsible for the BBB breakdown and neonatal pneumococcal severity...
  12. doi request reprint Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Eur J Pharmacol 697:158-64. 2012
    ..Although descriptive, our results demonstrate that cannabidiol has anti-inflammatory effects in pneumococcal meningitis and prevents cognitive sequel...
  13. doi request reprint Antioxidant treatment prevents cognitive impairment and oxidative damage in pneumococcal meningitis survivor rats
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000, Criciuma, SC, Brazil
    Metab Brain Dis 27:587-93. 2012
    ..Thus, we hypothesize that oxidative stress may be related to cognitive impairment in pneumococcal meningitis...
  14. ncbi request reprint Circulating concentrations, cerebral output of the CINC-1 and blood–brain barrier disruption in Wistar rats after pneumococcal meningitis induction
    T Barichello
    Laboratório de Microbiologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina INCT TM, Programa de Pós graduação em Ciências da Saúde PPGCS, Unidade Acadêmica de Ciências da Saúde UNASAU, Universidade do Extremo Sul Catarinense, SC, Brazil
    Eur J Clin Microbiol Infect Dis 31:2005-9. 2012
    ..The increase of CINC-1 occurred prior to the BBB breakdown. CINC-1 is a neutrophil chemoattractant and it may be related to early events in the pneumococcal meningitis pathophysiology...
  15. ncbi request reprint Pathophysiology of acute meningitis caused by Streptococcus pneumoniae and adjunctive therapy approaches
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Arq Neuropsiquiatr 70:366-72. 2012
    ..This cascade leads to lipid peroxidation, mitochondrial damage, blood-brain barrier breakdown contributing to cell injury during pneumococcal meningitis...
  16. doi request reprint Imipramine reverses depressive-like parameters in pneumococcal meningitis survivor rats
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    J Neural Transm 119:653-60. 2012
    ..Our results supported the hypothesis that the pneumococcal meningitis surviving rats showed depressive-like behavior and alterations in the hypothalamus-pituitary-adrenal axis...
  17. doi request reprint Oxidative stress, cytokine/chemokine and disruption of blood-brain barrier in neonate rats after meningitis by Streptococcus agalactiae
    Tatiana Barichello
    Laboratório de Microbiologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Neurochem Res 36:1922-30. 2011
    ....
  18. ncbi request reprint Depressive-like-behavior and proinflamatory interleukine levels in the brain of rats submitted to pneumococcal meningitis
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000 Criciuma, SC, Brazil
    Brain Res Bull 82:243-6. 2010
    ..pneumoniae. These findings suggest that the meningitis model could be a good research tool for the study of the biological mechanisms involved in the behavioral alterations secondary to pneumococcal meningitis...
  19. doi request reprint Time-dependent behavioral recovery after pneumococcal meningitis in rats
    Tatiana Barichello
    Laboratory of Microbiology and National Institute for Translational Medicine, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000, Criciuma, SC, Brazil
    J Neural Transm 117:819-26. 2010
    ..We demonstrated that some of the learning and memory impairment, demonstrated 10 days after the induction of meningitis, persists up to 30 days, but not 60 days after induction...
  20. ncbi request reprint Correlation between behavioral deficits and decreased brain-derived neurotrophic [correction of neurotrofic] factor in neonatal meningitis
    Tatiana Barichello
    Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    J Neuroimmunol 223:73-6. 2010
    ..The decrease in hippocampal BDNF levels correlated to impairment in memory in adult animals submitted to experimental meningitis in the neonatal period...
  21. doi request reprint Antibiotic therapy prevents, in part, the oxidative stress in the rat brain after meningitis induced by Streptococcus pneumoniae
    Tatiana Barichello
    Laboratory of Experimental Microbiology and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000 Criciuma, SC, Brazil
    Neurosci Lett 478:93-6. 2010
    ..Our results support the hypothesis that antibiotic treatment prevents, in part, the oxidative stress in the bacterial meningitis induced by Streptococcus pneumoniae...
  22. doi request reprint TNF-alpha, IL-1beta, IL-6, and cinc-1 levels in rat brain after meningitis induced by Streptococcus pneumoniae
    Tatiana Barichello
    Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    J Neuroimmunol 221:42-5. 2010
    ..01; p<0.01; p<0.01; F=16.86) after meningitis induction. Our data suggest that cytokine/chemokine levels can be putative biomarkers of brain damage in the first hours of the pneumococcal meningitis...
  23. doi request reprint Tumor necrosis factor alpha (TNF-alpha) levels in the brain and cerebrospinal fluid after meningitis induced by Streptococcus pneumoniae
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Neurosci Lett 467:217-9. 2009
    ..001).There was no alteration in the cortex. Our data suggest that TNF-alpha is involved in the pathophysiology of the pneumococcal meningitis and could be investigated as a putative biomarker for brain damage in the first hours...
  24. doi request reprint Early antibiotic administration prevents cognitive impairment induced by meningitis in rats
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Neurosci Lett 465:71-3. 2009
    ..The findings from this study suggest that early antibiotic administration is an effective strategy to prevent long-term cognitive impairment in a meningitis animal model...
  25. doi request reprint A kinetic study of the cytokine/chemokines levels and disruption of blood-brain barrier in infant rats after pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    J Neuroimmunol 233:12-7. 2011
    ..In conclusion, a peak of pro-inflammatory cytokine/chemokine is associated with disruption of the blood-brain barrier in infants with pneumococcal meningitis...
  26. doi request reprint Depressive-like parameters in sepsis survivor rats
    Clarissa M Comim
    Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Neurotox Res 17:279-86. 2010
    ..Our results supported the hypothesis that rats that survive sepsis show depressive-like behavior, alterations in the hypothalamus-pituitary-adrenal axis, and decreased BDNF levels in the hippocampus...
  27. ncbi request reprint Antioxidant treatment prevented late memory impairment in an animal model of sepsis
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental, Universidade do Extremo Sul Catarinense, Criciuma, Santa Catarina, Brazil
    Crit Care Med 35:2186-90. 2007
    ..Assess the effect of antioxidant treatment on late memory impairment and early hippocampus oxidative stress after cecal ligation and perforation...
  28. ncbi request reprint Klebsiella pneumoniae meningitis induces memory impairment and increases pro-inflammatory host response in the central nervous system of Wistar rats
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    J Med Microbiol 63:111-7. 2014
    ....
  29. ncbi request reprint Time-dependent behavioral recovery after sepsis in rats
    Lisiane Tuon
    Laboratorio de Neurociencias, Programa de Pós Graduação Ciências da Saúde, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000, Criciuma, SC, Brazil
    Intensive Care Med 34:1724-31. 2008
    ..To evaluate the cognitive performance in rats that survived sepsis induced by cecal ligation and puncture (CLP) after 10, 30 and 60 days...
  30. doi request reprint Erythropoietin reverts cognitive impairment and alters the oxidative parameters and energetic metabolism in sepsis animal model
    Clarissa M Comim
    Laboratory of Neurosciences and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciuma, SC 88806 000, Brazil
    J Neural Transm 119:1267-74. 2012
    ..Chronic use (4 days) reversed cognitive impairment in the sepsis animal model. Mortality rates were attenuated only during chronic treatment...
  31. ncbi request reprint Long lasting effects of electroconvulsive seizures on brain oxidative parameters
    Gustavo Feier
    Laboratorio de Neurociencias, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Neurochem Res 31:665-70. 2006
    ..Our findings demonstrated that there is a delayed increase after ECS in oxidative damage and decrease in antioxidant enzymes activities in hippocampus and striatum...
  32. ncbi request reprint Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats
    Tatiana Barichello
    Laboratório de Microbiologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Exp Biol Med (Maywood) 239:225-31. 2014
    ....
  33. ncbi request reprint Effects of maintenance electroshock on the oxidative damage parameters in the rat brain
    Luciano K Jornada
    Laboratorio de Neurociencias, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Neurochem Res 32:389-94. 2007
    ..Our findings, for the first time, demonstrated that after ECS maintenance we did protocol minimal oxidative damage in the brain regions, predominating absence of damage on the findings...
  34. pmc Memory-enhancing treatments reverse the impairment of inhibitory avoidance retention in sepsis-surviving rats
    Lisiane Tuon
    Laboratorio de Neurociencias, Programa de Pós Graduação Ciências da Saúde, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Av Universitaria, 1105, 88806 000 Criciuma, SC, Brasil
    Crit Care 12:R133. 2008
    ..Thus, we evaluated the effects of memory enhancers in sepsis-surviving rats...
  35. doi request reprint Rivastigmine reverses habituation memory impairment observed in sepsis survivor rats
    Clarissa M Comim
    Laboratórios de Neurociências, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Shock 32:270-1. 2009
    ..Therefore, rivastigmine reversed cognitive impairment in sepsis survivor rats in the open-field test...
  36. ncbi request reprint Evaluation of mitochondrial respiratory chain in the brain of rats after pneumococcal meningitis
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental and Instituto Nacional de Ciência e Tecnologia de Medicina Translacional, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Brain Res Bull 82:302-7. 2010
    ..Taking together previous reports and our present findings, we speculate that oxidative stress and metabolism impairment might contribute, at least in part, for the pathogenesis of pneumococcal meningitis...
  37. ncbi request reprint Oxidative variables in the rat brain after sepsis induced by cecal ligation and perforation
    Tatiana Barichello
    Laboratorio de Neurociencias, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Crit Care Med 34:886-9. 2006
    ..The present study was undertaken to assess different variables of oxidative stress in several brain structures after cecal ligation and perforation in the rat...
  38. ncbi request reprint No evidence for oxidative damage in the hippocampus after acute and chronic electroshock in rats
    Tatiana Barichello
    Laboratorio de Neurotoxicologia, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    Brain Res 1014:177-83. 2004
    ..Our findings, for the first time, demonstrated that after electroconvulsive shock, there is an increase in antioxidant enzyme activities and we cannot demonstrate oxidative damage in the hippocampus...
  39. ncbi request reprint Protein synthesis, PKA, and MAP kinase are differentially involved in short- and long-term memory in rats
    Joao Quevedo
    Laboratorio de Neurotoxicologia, Universidade do Extremo Sul Catarinense, Av Universitaria 1105, Criciúma 88806 000, SC, Brazil
    Behav Brain Res 154:339-43. 2004
    ..The results show that STM recruits PKA and MAPK, whereas, LTM depends on PKA activity and protein synthesis during the early post-training period...
  40. doi request reprint Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice
    Clarissa M Comim
    Laboratory of Neurosciences and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000 Criciuma, SC, Brazil
    Neurosci Lett 523:104-7. 2012
    ..In conclusion, we believe that the decreased BDNF levels in the hippocampus may be related with memory impairment without alterations on AChE activity...
  41. ncbi request reprint Cognitive impairment in the septic brain
    Clarissa M Comim
    Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, SC, Brazil
    Curr Neurovasc Res 6:194-203. 2009
    ..Here we discuss the clinical presentation and underlying pathophysiology of the encephalopathy and neurobiology of the cognitive impairment associated with sepsis...
  42. ncbi request reprint Cognitive impairment in sepsis survivors from cecal ligation and perforation
    Tatiana Barichello
    Laboratório de Fisiopatologia Experimental, Universidade do Extremo Sul Catarinense, Criciuma, Brazil
    Crit Care Med 33:221-3; discussion 262-3. 2005
    ..Critical illness survivors present long-term cognitive impairment, including problems with memory and learning. We evaluated cognitive performance in rats that survived from sepsis induced by cecal ligation and puncture (CLP)...
  43. doi request reprint Effects of acute treatment with amphetamine in locomotor activity in sepsis survivor rats
    Clarissa M Comim
    Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000 Criciuma, SC, Brazil
    J Neuroimmunol 212:145-7. 2009
    ..We suggest that, in part, dopamine pathway may be altered in sepsis...
  44. doi request reprint The septic brain
    Emilio L Streck
    Laboratório de Fisiopatologia Experimental, Programa de Pos Graduacao em Ciencias da Saude, Unidade Academica de Ciencias da Saude, Universidade do Extremo Sul Catarinense, 88806 000, Criciuma, SC, Brazil
    Neurochem Res 33:2171-7. 2008
    ..This review discusses the clinical presentation and underlying pathophysiology of the encephalopathy and cognitive impairment associated with sepsis...
  45. doi request reprint Pathophysiology of neonatal acute bacterial meningitis
    Tatiana Barichello
    Laboratório de Microbiologia Experimental e Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pos Graduacao em Ciencias da Saude, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    J Med Microbiol 62:1781-9. 2013
    ..This review summarizes information on the pathophysiology and adjuvant treatment of acute bacterial meningitis in neonates. ..
  46. doi request reprint Caspase-3 mediates in part hippocampal apoptosis in sepsis
    Clarissa M Comim
    Laboratory of Neurosciences and National Institute for Translational Medicine INCT TM, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806 000, Criciuma, Santa Catarina, Brazil
    Mol Neurobiol 47:394-8. 2013
    ..Caspase-3 is involved in part in apoptosis in the dentate gyrus cell layer of the hippocampus in septic rats submitted by CLP...