R Andreatini

Summary

Affiliation: Universidade Federal do Paran
Country: Brazil

Publications

  1. ncbi request reprint The relationship between anxiety and depression in animal models: a study using the forced swimming test and elevated plus-maze
    R Andreatini
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Universidade Federal do Parana, Curitiba, PR, Brasil
    Braz J Med Biol Res 32:1121-6. 1999
  2. ncbi request reprint Animal models: trait or state measure? The test-retest reliability of the elevated plus-maze and behavioral despair
    R Andreatini
    Department of Pharmacology, Universidade Federal do Parana, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 24:549-60. 2000
  3. ncbi request reprint Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study
    Roberto Andreatini
    Departamento de Farmacologia, Laboratório de Fsisiologia e Farmacologia do Sistema Nervoso Central, Universidade Federal do Parana, CP 19031, Curitiba, PR, Brazil, 81540 970
    Phytother Res 16:650-4. 2002
  4. doi request reprint Anxiolytic-like effect of chronic treatment with Erythrina velutina extract in the elevated plus-maze test
    I M Raupp
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, PO Box 19031, 81531 990, Curitiba, PR, Brazil
    J Ethnopharmacol 118:295-9. 2008
  5. ncbi request reprint Veratrine blocks the lamotrigine-induced swimming increase and immobility decrease in the modified forced swimming test
    F T Codagnone
    Department of Pharmacology, Universidade Federal do Parana, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politécnico C P 19031, 81540 990 Curitiba PR Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:1307-11. 2007
  6. ncbi request reprint Repeated paroxetine treatment reverses anhedonia induced in rats by chronic mild stress or dexamethasone
    P C Casarotto
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politécnico C P 19031, 81540 990 Curitiba PR Brazil
    Eur Neuropsychopharmacol 17:735-42. 2007
  7. doi request reprint Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models
    M Pereira
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, 81540 990, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 35:1636-44. 2011
  8. ncbi request reprint Effect of Hypericum perforatum on marble-burying by mice
    L L Skalisz
    Departamento de Farmacologia, Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Universidade Federal do Parana, Curitiba, PR, Brazil
    Phytother Res 18:399-402. 2004
  9. ncbi request reprint Effects of fish oil on the central nervous system: a new potential antidepressant?
    K Naliwaiko
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Fisiologia e Farmacologia, Universidade Federal do Parana, 81 531 990 Curitiba, PR, Brazil
    Nutr Neurosci 7:91-9. 2004
  10. ncbi request reprint Memory disruption in rats with nigral lesions induced by MPTP: a model for early Parkinson's disease amnesia
    C Da Cunha
    Laboratório de Fisiologia e Farmacologia do SNC, Departamento de Farmacologia, UFPR, CP 19 031, 81 531 990 Curitiba PR, Brazil
    Behav Brain Res 124:9-18. 2001

Collaborators

  • M Pereira
  • R N Takahashi
  • Sergio Tufik
  • Juliana C Perry
  • Claudio Da Cunha
  • Maria A B F Vital
  • Vanessa Beijamini
  • I M Raupp
  • Lea R Chioca
  • Angela Braga Reksidler
  • José Carlos Miranda Torrejais
  • Angela B Reksidler
  • P C Casarotto
  • F T Codagnone
  • Fernando T Consoni
  • Patricia Andreia Dombrowski
  • Patricia A Dombrowski
  • Kleber Meneghel Vargas
  • L L Skalisz
  • Luciana Auchewski
  • João C Castilho
  • K Naliwaiko
  • Venessa Beijamini
  • Renata C Dutra
  • Luana L Skalisz
  • C Da Cunha
  • Patrícia Dombrowski
  • Camila Castilho Machado Rosa
  • Sílvio Marques Zanata
  • C Ghislandi
  • H A Trebien
  • E L Cavalcanti E Silva
  • Maria Aparecida Barbato Frazão Vital
  • Estela M Losso
  • Marcelo Meira Santos Lima
  • Monica Levy Andersen
  • S Virtuoso
  • Inara M Raupp
  • A Sereniki
  • O G Miguel
  • Roseli Boerngen-Lacerda
  • F T Consoni
  • Jeff Chandler
  • Evellyn C Wietzikoski
  • A L S Rodrigues
  • Samantha Wietzikoski
  • Marcelo M S Lima
  • Newton S Canteras
  • Marcelo M Ferro
  • Marcio H C Silva
  • M A B F Vital
  • Silvio M Zanata
  • Hidevaldo B Machado
  • Lineane H Fernandes
  • E F Martins
  • L C Fernandes
  • R Curi
  • B H Oliveira
  • M I Bellissimo
  • A C Ferraz
  • R V da Fonseca
  • Roseli Boerngen de Lacerda
  • R L E Araújo
  • José Carlos F Galduróz
  • V Beijamini
  • J C Castilho
  • Ana Paula Andreazza
  • Samia L Joca
  • M A Vital
  • M S Gevaerd
  • N S Canteras
  • E Miyoshi
  • R Silveira

Detail Information

Publications27

  1. ncbi request reprint The relationship between anxiety and depression in animal models: a study using the forced swimming test and elevated plus-maze
    R Andreatini
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Universidade Federal do Parana, Curitiba, PR, Brasil
    Braz J Med Biol Res 32:1121-6. 1999
    ..18). These data suggest that mouse behavior in the elevated plus-maze is not related to behavior in the forced swimming test and that a forced swimming test before the plus-maze has an anxiogenic effect even after a one-week interval...
  2. ncbi request reprint Animal models: trait or state measure? The test-retest reliability of the elevated plus-maze and behavioral despair
    R Andreatini
    Department of Pharmacology, Universidade Federal do Parana, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 24:549-60. 2000
    ..Therefore they appear to be not appropriate to evaluate trait characteristics which are supposed to be stable over time without treatment...
  3. ncbi request reprint Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study
    Roberto Andreatini
    Departamento de Farmacologia, Laboratório de Fsisiologia e Farmacologia do Sistema Nervoso Central, Universidade Federal do Parana, CP 19031, Curitiba, PR, Brazil, 81540 970
    Phytother Res 16:650-4. 2002
    ..However, since the number of subjects per group was very small, the present results must be viewed as preliminary. Thus, further studies addressing this issue are warranted...
  4. doi request reprint Anxiolytic-like effect of chronic treatment with Erythrina velutina extract in the elevated plus-maze test
    I M Raupp
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, PO Box 19031, 81531 990, Curitiba, PR, Brazil
    J Ethnopharmacol 118:295-9. 2008
    ..Chlordiazepoxide and imipramine were used as standard drugs...
  5. ncbi request reprint Veratrine blocks the lamotrigine-induced swimming increase and immobility decrease in the modified forced swimming test
    F T Codagnone
    Department of Pharmacology, Universidade Federal do Parana, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politécnico C P 19031, 81540 990 Curitiba PR Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:1307-11. 2007
    ..These results suggest that the serotonergic effect of lamotrigine in the modified forced swimming test is dependent on Na(+) voltage sensitive channel blockade, whereas its noradrenergic effect is not...
  6. ncbi request reprint Repeated paroxetine treatment reverses anhedonia induced in rats by chronic mild stress or dexamethasone
    P C Casarotto
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politécnico C P 19031, 81540 990 Curitiba PR Brazil
    Eur Neuropsychopharmacol 17:735-42. 2007
    ..Thus, the present study adds new data to the evidence supporting an important role for glucocorticoid in depression...
  7. doi request reprint Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models
    M Pereira
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, 81540 990, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 35:1636-44. 2011
    ..Thus, myricitrin exhibited an antipsychotic-like profile at doses that did not induce catalepsy, and this effect may be related to nitrergic action...
  8. ncbi request reprint Effect of Hypericum perforatum on marble-burying by mice
    L L Skalisz
    Departamento de Farmacologia, Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Universidade Federal do Parana, Curitiba, PR, Brazil
    Phytother Res 18:399-402. 2004
    ....
  9. ncbi request reprint Effects of fish oil on the central nervous system: a new potential antidepressant?
    K Naliwaiko
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Fisiologia e Farmacologia, Universidade Federal do Parana, 81 531 990 Curitiba, PR, Brazil
    Nutr Neurosci 7:91-9. 2004
    ..01) when compared to C and CF rats. We conclude that lifelong intake of FO was able to induce an antidepressant effect with EPA and DHA concentration increased in the cerebral cortex and hippocampus...
  10. ncbi request reprint Memory disruption in rats with nigral lesions induced by MPTP: a model for early Parkinson's disease amnesia
    C Da Cunha
    Laboratório de Fisiologia e Farmacologia do SNC, Departamento de Farmacologia, UFPR, CP 19 031, 81 531 990 Curitiba PR, Brazil
    Behav Brain Res 124:9-18. 2001
    ..In addition, this study is presented as a model of early Parkinson's Disease amnesia and is discussed in terms of the importance of the nigrostriatal pathway to memory acquisition and storage processes...
  11. ncbi request reprint Effects of Hypericum perforatum and paroxetine on rat performance in the elevated T-maze
    Venessa Beijamini
    Departamento de Farmacologia, Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Setor de Ciencias Biologicas, Centro Politecnico, Universidade Federal do Parana, P O Box 19031, 81531 990, PR, Curitiba, Brazil
    Pharmacol Res 48:199-207. 2003
    ..No effect on locomotor activity was found with any treatment. Thus, the results suggest that H. perforatum extract could exert an anxiolytic and antipanic effect...
  12. ncbi request reprint Repeated intranigral MPTP administration: a new protocol of prolonged locomotor impairment mimicking Parkinson's disease
    Angela Braga Reksidler
    Departamento de Farmacologia, Universidade Federal do Parana, Av Francisco H dos Santos s n, Jardim das Américas 81531 990, Curitiba, PR, Brazil
    J Neurosci Methods 167:268-77. 2008
    ..The current protocol provided relevant insights about TH expression and irreversible locomotor impairment...
  13. ncbi request reprint Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease
    Claudio Da Cunha
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamentos de Farmacologia, Bioquímica e Biologia Molecular, UFPR, Curitiba, Brazil
    Neurobiol Learn Mem 87:451-63. 2007
    ..However, the simultaneous presence of the escape platform and extra-maze cues (irrespective of their relational configuration) during the pre-training sessions proved to be necessary for this improving effect to occur...
  14. ncbi request reprint Reversible inactivation of the dorsal raphe nucleus blocked the antipanic-like effect of chronic imipramine in the elevated T-maze
    Patricia Andreia Dombrowski
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, P O Box 19031, 81531 990, Curitiba, PR, Brazil
    Neurosci Lett 407:80-5. 2006
    ..Moreover, they suggest that the DRN exerts a crucial role in the antipanic-like effect of chronic imipramine in the ETM...
  15. ncbi request reprint Amphetamine and pentylenetetrazole given post-trial 1 enhance one-trial tolerance to the anxiolytic effect of diazepam in the elevated plus-maze in mice
    Kleber Meneghel Vargas
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, CP 19031, Curitiba, PR 81531 990, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 30:1394-402. 2006
    ..0 mg/kg) did not show one-trial tolerance 48 h after trial 1. Taken as a whole, these data support the hypothesis that memory is involved in the lack of an anxiolytic effect in the elevated plus-maze trial 2...
  16. ncbi request reprint Picrotoxin blocks the anxiolytic- and panicolytic-like effects of sodium valproate in the rat elevated T-maze
    Patricia A Dombrowski
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politécnico C P 19031, 81540 990 Curitiba, PR, Brazil
    Eur J Pharmacol 537:72-6. 2006
    ..These data suggest that sodium valproate exerts anxiolytic-like and panicolytic-like effects in the elevated T-maze and that these effects were mediated by picrotoxin-sensitive GABA type A receptors...
  17. ncbi request reprint Intra-nigral MPTP lesion in rats: behavioral and autoradiography studies
    Juliana C Perry
    Universidade Federal do Parana, Setor de Ciencias Biologicas, Departamento de Farmacologia, Av Francisco H dos Santos s n, CEP 81 531 990, Caixa Postal 19031, Curitiba Parana, Brazil
    Exp Neurol 195:322-9. 2005
    ..These alterations might be related to the occurrence and recovery of motor impairment observed in MPTP-lesioned rats...
  18. ncbi request reprint Effects of Hypericum perforatum and paroxetine in the mouse defense test battery
    Vanessa Beijamini
    Departamento de Farmacologia, Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Centro Politecnico Setor de Ciencias Biologicas, Universidade Federal do Parana, C P 19031, CEP 81531 990, Curitiba, PR, Brazil
    Pharmacol Biochem Behav 74:1015-24. 2003
    ..perforatum extract. However, it should be emphasized that the risk assessment (the main index of anxiety) was not affected by the extract, while the attack reactions were only weakly modified...
  19. ncbi request reprint Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats
    Juliana Cini Perry
    Department of Pharmacology, Federal University of Parana, Av Francisco H dos Santos s n, 19031 Curitiba, PR, Brazil
    Eur J Pharmacol 484:225-33. 2004
    ..In conclusion, the data suggest that MPTP is a good model to study the early impairment associated with Parkinson's disease and phosphatidylserine did not improve the memory impairment induced by MPTP...
  20. doi request reprint The elevated T-maze as a measure of two types of defensive reactions: a factor analysis
    José Carlos Miranda Torrejais
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Universidade Federal do Parana, Curitiba, Brazil
    Brain Res Bull 76:376-9. 2008
    ..Baseline avoidance did not load together with locomotor activity in the open-field. These results indicate that the elevated T-maze generates two different defensive behaviours...
  21. ncbi request reprint Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats
    Lea R Chioca
    Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana UFPR, Centro Politécnico PO Box 19031, 81540 990 Curitiba, PR, Brazil
    Eur J Pharmacol 579:196-201. 2008
    ..Mild dental fluorosis in rat incisor teeth was found in the 50 and 100 ppm NaF groups. Overall, these results suggest that moderate intoxication with sodium fluoride has potentially deleterious effects on learning and memory...
  22. ncbi request reprint [Evaluation of the medical orientation for the benzodiazepine side effects]
    Luciana Auchewski
    Departamento de Farmacologia, Universidade Federal do Parana, Curitiba, PR, Brasil
    Rev Bras Psiquiatr 26:24-31. 2004
    ..In the present study it was evaluated the quality of the medical directions given to patients about those side effects...
  23. ncbi request reprint Behavioral effects of MK-801 on reserpine-treated mice
    Renata C Dutra
    Laboratório de Fisiologia e Farmacologia do SNC Centro Politécnico, Department of Pharmacology, Federal University of Parana, Curitiba, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 26:487-95. 2002
    ..The glutamatergic blockage produced by NMDA can restore these signs, such as vacuous chewing movements, tongue protrusions, catalepsy and tremor according to the employed model...
  24. ncbi request reprint Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association
    Luana L Skalisz
    Departamento de Farmacologia, Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Centro Politecnico Setor de Ciencias Biologicas, Universidade Federal do Parana, PO Box 19031, 81531 990, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 26:879-83. 2002
    ..This suggests that the RES model shows an important aspect of face validity for the depressive state associated with PD, i.e., phenomenological similarities between the model and the situation being modeled...
  25. ncbi request reprint The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats
    Angela B Reksidler
    Departamento de Farmacologia, Universidade Federal do Parana, Curitiba, PR, Brazil
    Eur J Pharmacol 560:163-75. 2007
    ....
  26. ncbi request reprint Phosphatidylserine: an antidepressive or a cognitive enhancer?
    João C Castilho
    Departamento de Farmacologia, Centro Politecnico Setor de Ciencias Biologicas, Universidade Federal do Parana, Av Francisco H dos Santos s n, PO Box 19031, 81531 990, Curitiba, PR, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 28:731-8. 2004
    ..Taken together, the present results are suggestive of an antidepressive effect of BC-PS in the forced swimming test in rats but not of a cognitive enhancer effect of the drug in the water maze test...
  27. ncbi request reprint Dual monoamine modulation for the antidepressant-like effect of lamotrigine in the modified forced swimming test
    Fernando T Consoni
    Laboratorio de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Setor de Ciencias Biologicas, Universidade Federal do Parana, Centro Politecnico, PO Box 19031, 81531 990, Curitiba, PR, Brazil
    Eur Neuropsychopharmacol 16:451-8. 2006
    ..The present study indicates that the antidepressant-like effect of lamotrigine is probably related to noradrenergic/serotonergic systems...