Ciomar Aparecida Bersani Amado


Affiliation: Universidade Estadual de Maring
Country: Brazil


  1. Vicentini F, Barbosa M, Fortunato M, Amado C, Comar J, Longhini R, et al. Treatment with Trichilia catigua ethyl-acetate fraction improves healing and reduces oxidative stress in TNBS-induced colitis in rats. Biomed Pharmacother. 2018;107:194-202 pubmed publisher
    ..catigua EAF was more effective than intrarectal administration of the extract. In conclusion, T. catigua EAF treatment normalized oxidative stress parameters in blood and reduced the degree of acute inflammation in TNBS colitis. ..
  2. de Albuquerque Botura C, Bersani Amado L, Zacarias Júnior A, Boreli S, Stecca N, da Rocha B, et al. Behçet's Disease: Pulmonary Aneurysm Resolution with Oral Therapy and HLA B72 Allele Association. Clin Med Res. 2018;16:37-40 pubmed publisher
    ..After 12 months of treatment, the clinical condition completely resolved. ..
  3. Estevão Silva C, Ames F, Silva Comar F, Kummer R, Tronco R, Cuman R, et al. Fish Oil and Adjuvant-Induced Arthritis: Inhibitory Effect on Leukocyte Recruitment. Inflammation. 2016;39:320-326 pubmed publisher
    ..Together, our data provide evidence that FOP plays an important inhibitory role in the recruitment of leukocytes into the joint cavity of arthritic rats. ..
  4. Baroni S, da Rocha B, Oliveira de Melo J, Comar J, Caparroz Assef S, Bersani Amado C. Hydroethanolic extract of Smallanthus sonchifolius leaves improves hyperglycemia of streptozotocin induced neonatal diabetic rats. Asian Pac J Trop Med. 2016;9:432-6 pubmed publisher
    ..The data suggest that yacon extract reduces hyperglycemia, possibly by improving insulin sensibility through its phytochemicals constituents (phenolic compounds). ..
  5. Wisniewski Rebecca E, Rocha B, Wiirzler L, Cuman R, Velazquez Martinez C, Bersani Amado C. Synergistic effects of anethole and ibuprofen in acute inflammatory response. Chem Biol Interact. 2015;242:247-53 pubmed publisher
    ..The isobologram analysis evidenced a synergistic effect between ibuprofen and anethole, because the combination of drugs showed a higher inhibitory potential than either drug alone. ..
  6. Barbosa C, Bracht L, Ames F, de Souza Silva Comar F, Tronco R, Bersani Amado C. Effects of Ezetimibe, Simvastatin, and their Combination on Inflammatory Parameters in a Rat Model of Adjuvant-Induced Arthritis. Inflammation. 2017;40:717-724 pubmed publisher
    ..The treatments reduced the levels of proinflammatory cytokines and increased the levels of the antiinflammatory cytokine IL-10, indicating antiinflammatory properties of these drugs in this experimental model of inflammation. ..
  7. de Arruda L, Ames F, de Morais D, Grespan R, Gil A, Silva M, et al. A single administration of fish oil inhibits the acute inflammatory response in rats. Asian Pac J Trop Med. 2017;10:765-772 pubmed publisher
    ..This effect might be attributable to a direct inhibitory effect of FO on the production or release of inflammatory mediators that are involved in the pathological processes evaluated herein. ..
  8. de Albuquerque Botura C, da Rocha B, Balensiefer T, Ames F, Bersani Amado C, Nakamura Cuman R. Oral pharmacological treatment for patent ductus arteriosus in premature neonates with hemodynamic repercussions. Asian Pac J Trop Med. 2017;10:1080-1083 pubmed publisher
    ..A significant reduction of diuresis occurred in neonates who were treated with indomethacin, either as a first-line treatment or after the failure of ibuprofen or paracetamol. ..
  9. da Rocha B, Ritter A, Ames F, Gonçalves O, Leimann F, Bracht L, et al. Acetaminophen-induced hepatotoxicity: Preventive effect of trans anethole. Biomed Pharmacother. 2017;86:213-220 pubmed publisher
    ..Thus, our results demonstrate a possible protective effect of trans anethole on the hepatotoxicity induced by APAP. ..