Research Topics

Leticia Helena Theodoro


Country: Brazil


  1. Longo M, Gouveia Garcia V, Ervolino E, Ferro Alves M, Duque C, Wainwright M, et al. Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: histomorphometrical, immunohistochemical, immunological and microbiological analyses. Photodiagnosis Photodyn Ther. 2019;25:92-102 pubmed publisher
    ..Repeated sessions of aPDT as an adjunct or alternative therapy were effective at reducing ABL, regulating bone metabolism, and reducing Prevotella nigrescens and Aggregatibacter actinomycetemcomitans. ..
  2. Theodoro L, Assem N, Longo M, Alves M, Duque C, Stipp R, et al. Treatment of periodontitis in smokers with multiple sessions of antimicrobial photodynamic therapy or systemic antibiotics: A randomized clinical trial. Photodiagnosis Photodyn Ther. 2018;22:217-222 pubmed publisher
    ..In smokers with periodontitis, the MTZ + AMX and aPDT treatments significantly improved the effects of SRP. ..
  3. Gusman D, Mello Neto J, Alves B, Matheus H, Ervolino E, Theodoro L, et al. Periodontal disease severity in subjects with dementia: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2018;76:147-159 pubmed publisher
  4. Theodoro L, Lopes A, Nuernberg M, Cláudio M, Miessi D, Alves M, et al. Comparison of repeated applications of aPDT with amoxicillin and metronidazole in the treatment of chronic periodontitis: A short-term study. J Photochem Photobiol B. 2017;174:364-369 pubmed publisher
  5. de Almeida J, de Moraes R, Gusman D, Faleiros P, Nagata M, Garcia V, et al. Influence of low-level laser therapy on the healing process of autogenous bone block grafts in the jaws of systemically nicotine-modified rats: A histomorphometric study. Arch Oral Biol. 2017;75:21-30 pubmed publisher
    ..37%±11.93%) and 28days (SS-BG 50.31%±2.69% versus SS-BG/LLLT 58 19%±12.32% and NIC-BG 36.89%±8.40% versus NIC-BG/LLLT 45.81%±6.03%). Nicotine harms bone formation in the bed-graft interface and LLLT action can mitigate this. ..
  6. Theodoro L, Longo M, Novaes V, Miessi D, Ferro Alves M, Ervolino E, et al. Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil. Support Care Cancer. 2017;25:3261-3271 pubmed publisher
    ..LLLT and aPDT adjuvant to SRP minimized the effects of 5-FU on periodontal disease. Furthermore, aPDT promoted greater benefits in bone loss control and inflammatory response. ..
  7. Theodoro L, Ferro Alves M, Longo M, Nuernberg M, Ferreira R, Andreati A, et al. Curcumin photodynamic effect in the treatment of the induced periodontitis in rats. Lasers Med Sci. 2017;32:1783-1791 pubmed publisher
    ..Treatments resulted in smaller numbers of TRAP-positive cells compared to the NT group. aPDT as monotherapy using curcumin as a photosensitizer and LED as the light source was effective in the treatment of induced periodontitis in rats. ..