Luiz F Silva

Summary

Country: Brazil

Publications

  1. ncbi Iodine(III)-promoted ring contraction of 1,2-dihydronaphthalenes: a diastereoselective total synthesis of (+/-)-indatraline
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 9:1433-6. 2007
  2. ncbi Hypervalent iodine-mediated ring contraction reactions
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, CP 26077, CEP 05513 970, Sao Paulo SP, Brazil
    Molecules 11:421-34. 2006
  3. ncbi Reaction of thallium(III) salts with homoallylic alcohols: ring contraction vs. dimethoxylation
    Luiz F Silvia
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748 CP 26077, CEP 05513 970, Sao Paulo, Brazil
    Molecules 10:1419-28. 2005
  4. ncbi Iodine(III)-promoted ring expansion of 1-vinylcycloalkanol derivatives: a metal-free approach toward seven-membered rings
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Avenida Professor Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 10:1017-20. 2008
  5. ncbi A diastereoselective total synthesis of trans-trikentrin A: a ring contraction approach
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 10:5417-20. 2008
  6. ncbi Indatraline: synthesis and effect on the motor activity of Wistar rats
    Marcia Kameyama
    Department of Experimental Psychology, Institute of Psychology, University of Sao Paulo, USP, Sao Paulo, SP CEP 05508 030, Brazil
    Molecules 16:9421-38. 2011
  7. ncbi A ring contraction strategy toward a diastereoselective total synthesis of (+)-bakkenolide A
    Vânia M T Carneiro
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    J Org Chem 75:2877-82. 2010
  8. ncbi Populene d analogues: design, concise synthesis and antiproliferative activity
    Kachi R Kishore Kumar Reddy
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP São Paulo 05513 970, SP, Brazil
    Molecules 17:9621-30. 2012
  9. ncbi Total synthesis of (+)-trans-trikentrin A
    Iris R M Tébéka
    Instituto de Quimica, Universidade de Sao Paulo, Brazil
    Chemistry 18:16890-901. 2012
  10. ncbi (+)- and (-)-mutisianthol: first total synthesis, absolute configuration, and antitumor activity
    Graziela G Bianco
    Department of Chemistry, Institute of Chemistry, University of Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    J Org Chem 74:2561-6. 2009

Collaborators

  • Helena M C Ferraz
  • Andreas Pfaltz
  • João E de Carvalho
  • Ana L T G Ruiz
  • Iris R M Tébéka
  • Giovanna B Longato
  • Kachi R Kishore Kumar Reddy
  • Marcia Kameyama
  • Vânia M T Carneiro
  • Graziela G Bianco
  • Marcus V Craveiro
  • Luiz F Silvia
  • Miriam Garcia-Mijares
  • Fernanda A Siqueira
  • Maria T A Silva
  • Eloisa E Ishikawa
  • Tiago O Vieira
  • Leticia V Costa-Lotufo
  • Arinice M Costa
  • Marcus G Schrems
  • Claudia Pessoa
  • Manoel O de Moraes

Detail Information

Publications10

  1. ncbi Iodine(III)-promoted ring contraction of 1,2-dihydronaphthalenes: a diastereoselective total synthesis of (+/-)-indatraline
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 9:1433-6. 2007
    ..The oxidative rearrangement of other 1,2-dihydronaphthalenes was also investigated, generalizing this method to obtain indans...
  2. ncbi Hypervalent iodine-mediated ring contraction reactions
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, CP 26077, CEP 05513 970, Sao Paulo SP, Brazil
    Molecules 11:421-34. 2006
    ..This review covers all the literature related to the ring contraction of cyclic ketones and olefins promoted by iodine(III) species...
  3. ncbi Reaction of thallium(III) salts with homoallylic alcohols: ring contraction vs. dimethoxylation
    Luiz F Silvia
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748 CP 26077, CEP 05513 970, Sao Paulo, Brazil
    Molecules 10:1419-28. 2005
    ..These compounds were formed by a thallium-promoted addition of methanol to the double bond...
  4. ncbi Iodine(III)-promoted ring expansion of 1-vinylcycloalkanol derivatives: a metal-free approach toward seven-membered rings
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Avenida Professor Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 10:1017-20. 2008
    ..The reaction condition can be easily adjusted to give seven-membered rings bearing different functional groups. A route to medium-ring lactones was also developed...
  5. ncbi A diastereoselective total synthesis of trans-trikentrin A: a ring contraction approach
    Luiz F Silva
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    Org Lett 10:5417-20. 2008
    ..Other key transformations are the Bartoli's reaction to construct the heterocyclic ring and a Heck coupling to add the carbons atom that will originate the nonaromatic cycle...
  6. ncbi Indatraline: synthesis and effect on the motor activity of Wistar rats
    Marcia Kameyama
    Department of Experimental Psychology, Institute of Psychology, University of Sao Paulo, USP, Sao Paulo, SP CEP 05508 030, Brazil
    Molecules 16:9421-38. 2011
    ..The results suggest that indatraline has a long lasting effect on motor activity and add evidence in favor of the potential use of that compound as a substitute in cocaine addiction...
  7. ncbi A ring contraction strategy toward a diastereoselective total synthesis of (+)-bakkenolide A
    Vânia M T Carneiro
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    J Org Chem 75:2877-82. 2010
    ..Furthermore, during this work, the absolute configuration of a trinorsesquiterpene isolated from Senecio humillimus was assigned...
  8. ncbi Populene d analogues: design, concise synthesis and antiproliferative activity
    Kachi R Kishore Kumar Reddy
    Instituto de Quimica, Universidade de Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP São Paulo 05513 970, SP, Brazil
    Molecules 17:9621-30. 2012
    ..Among them, an isochromene with moderate activity (mean logGI(50) = 0.91) was found. Additionally, compounds with selectivity toward the tumor cell lines NCI-ADR/RES, OVCAR-3, and HT29 were discovered...
  9. ncbi Total synthesis of (+)-trans-trikentrin A
    Iris R M Tébéka
    Instituto de Quimica, Universidade de Sao Paulo, Brazil
    Chemistry 18:16890-901. 2012
    ..The antiproliferative activities of the natural product and related intermediates have been tested against human tumor cell lines, leading to the discovery of new compounds with potent antitumor activity...
  10. ncbi (+)- and (-)-mutisianthol: first total synthesis, absolute configuration, and antitumor activity
    Graziela G Bianco
    Department of Chemistry, Institute of Chemistry, University of Sao Paulo, Av Prof Lineu Prestes, 748, CP 26077, CEP 05513 970 Sao Paulo SP, Brazil
    J Org Chem 74:2561-6. 2009
    ..The target molecules show moderate activity against the human tumor cell lines SF-295, HCT-8, and MDA-MB-435...