Research Topics
| José Maurício SforcinSummaryCountry: Brazil Publications
| Collaborators
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Detail Information
Publications
Lemongrass effects on IL-1beta and IL-6 production by macrophagesJ M Sforcin
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
Nat Prod Res 23:1151-9. 2009..Taken together, these data suggest an anti-inflammatory action of this natural product...
Propolis: is there a potential for the development of new drugs?José Maurício Sforcin
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618 000 Botucatu, SP, Brazil
J Ethnopharmacol 133:253-60. 2011....
Propolis and the immune system: a reviewJ M Sforcin
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618 000 Botucatu, SP, Brazil
J Ethnopharmacol 113:1-14. 2007..This review opens a new perspective on the investigation of propolis biological properties, mainly with respect to the immune system...
Effect of a leukotriene inhibitor (MK886) on nitric oxide and hydrogen peroxide production by macrophages of acutely and chronically stressed miceJosé Maurício Sforcin
Departamento de Microbiologia e Imunologia, Instituto de Biociencias, UNESP, Botucatu, SP 18618 000, Brazil
J Pharm Pharmacol 59:1249-54. 2007..Our data suggest an important role of leukotrienes in NO synthesis, which is important in controlling replication of several infectious agents, mainly in stressed and immunosuppressed animals...
Th1/Th2 cytokines' expression and production by propolis-treated miceClaudio Lera Orsatti
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
J Ethnopharmacol 129:314-8. 2010..The goal of this work was to evaluate the effect of propolis administration over a short-term to mice on Th1 (IL-2 and IFN-gamma) and Th2 (IL-4 and IL-10) cytokines' expression and production...
Th1/Th2 cytokine production by clove-treated miceTatiana Fernanda Bachiega
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
Nat Prod Res 23:1552-8. 2009..Further studies dealing with cytokine expression and production will provide a better understanding of clove's immunomodulatory and anti-inflammatory actions, using different extract concentrations and different intake periods...
Propolis effects on pro-inflammatory cytokine production and Toll-like receptor 2 and 4 expression in stressed miceAna Carolina Pagliarone
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618 000 Botucatu, SP, Brazil
Int Immunopharmacol 9:1352-6. 2009....
Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophagesTatiana Fernanda Bachiega
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, Brazil
J Pharm Pharmacol 64:610-6. 2012..Herein we have analysed the immunomodulatory/anti-inflammatory effect of clove and eugenol on cytokine production (interleukin (IL)-1β, IL-6 and IL-10) in vitro...
Propolis immunomodulatory activity on TLR-2 and TLR-4 expression by chronically stressed miceClaudio Lera Orsatti
Department of Microbiology and Immunology, Biosciences Institute, Sao Paulo State University, Botucatu, Sao Paulo, Brazil
Nat Prod Res 26:446-53. 2012....
Polymerase chain reaction detection of enterotoxins genes in coagulase-negative staphylococci isolated from Brazilian Minas cheeseVera Lucia Mores Rall
Department of Microbiology and Immunology, Institute of Biosciences, Sao Paulo State University UNESP, Botucatu, Sao Paulo, Brazil
Foodborne Pathog Dis 7:1121-3. 2010..It is essential to understand the real role of CNS in food, and based on the presence of enterotoxin genes, CNS should not be ignored in epidemiological investigations of foodborne outbreaks...
In vitro and in vivo effects of clove on pro-inflammatory cytokines production by macrophagesT G Rodrigues
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
Nat Prod Res 23:319-26. 2009..Eugenol was found to be the major component of the clove extract and essential oil, and probably is the causative agent of cytokine inhibition. Taken together, these data suggest an anti-inflammatory action of this spice...
Propolis: Effect of different concentrations, extracts and intake period on seric biochemical variablesF Mani
Department of Chemistry and Biochemistry, Biosciences Institute, UNESP, 18600 000 Botucatu, SP, Brazil
J Ethnopharmacol 105:95-8. 2006..On the basis of our findings, since propolis does not induce any significant change in seric parameters, it is claimed that long-term administration of propolis might not have any cardiac injury...
Propolis immunomodulatory action in vivo on Toll-like receptors 2 and 4 expression and on pro-inflammatory cytokines production in miceC L Orsatti
Department of Microbiology and Immunology, Bioscience Institute, UNESP, 18618 000 SP, Brazil
Phytother Res 24:1141-6. 2010..One may conclude that propolis activated the initial steps of the immune response by upregulating TLRs expression and the production of pro-inflammatory cytokines in mice, modulating the mechanisms of the innate immunity...
Propolis effect on Th1/Th2 cytokines production by acutely stressed miceAna Carolina Pagliarone
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618 000 Botucatu, SP, Brazil
J Ethnopharmacol 125:230-3. 2009..The purpose of this study was to investigate propolis effect on Th1/Th2 cytokines production by spleen cells of acutely stressed mice. Serum corticosterone concentration was determined as a stress indicator...
Lemongrass and citral effect on cytokines production by murine macrophagesTatiana Fernanda Bachiega
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP 18618 970, Brazil
J Ethnopharmacol 137:909-13. 2011..Thus, the goal of this work was to analyze the effect of LG and citral on cytokines production (IL-1β, IL-6 and IL-10) in vitro, as well as before or after LPS incubation...
The effect of propolis on CCL5 and IFN-γ expression by peripheral blood mononuclear cells from leishmaniasis patientsMarla Karine Amarante
Department of Pathological Sciences, UEL, Londrina, PR, Brazil
J Pharm Pharmacol 64:154-60. 2012....
Effect of three vegetal sources of propolis on macrophages activationF C Lopes
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
Phytomedicine 10:343. 2003
Effects of propolis from Brazil and Bulgaria on fungicidal activity of macrophages against Paracoccidioides brasiliensisJ M Murad
Department of Microbiology and Immunology, Biosciences Institute, IB-UNESP, 18618-000 Botucatu, SP, Brazil
J Ethnopharmacol 79:331-4. 2002..brasiliensis. Data suggest an increase in the fungicidal activity of macrophages by propolis stimulation, independently from its geographic origin...
Effect of propolis, some isolated compounds and its source plant on antibody productionJ M Sforcin
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618-000 Botucatu, S.P, Brazil
J Ethnopharmacol 98:301-5. 2005..Propolis action is a consequence of plant-derived products with synergic effects, while isolated compounds or extracts from its plant sources had no effect in this assay...
Characterisation of protease activity in extracellular products secreted by Giardia duodenalis trophozoites treated with propolisErica Boarato David
Department of Parasitology, Biosciences Institute, Universidade Estadual Paulista, Botucatu, SP, Brazil
Nat Prod Res 26:370-4. 2012..Although propolis had no effect on the proteolytic activity, further studies could identify the active constituents responsible for propolis antigiardial activity and their mechanisms of action...
Green brazilian propolis action on macrophages and lymphoid organs of chronically stressed miceFabiane Missima
Department of Microbiology and Immunology, Biosciences Institute, UNESP, 18618 000 Botucatu, S P, Brazil
Evid Based Complement Alternat Med 5:71-5. 2008..Propolis treatment counteracted the alterations found in the spleen of stressed mice. New research is being carried out in order to elucidate propolis immunomodulatory action during stress...
Anti-poliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real-time PCRM C Búfalo
Department of Microbiology and Immunology, Biosciences Institute, UNESP, Botucatu, SP, Brazil
J Appl Microbiol 107:1669-80. 2009....
In vitro effects of propolis on Giardia duodenalis trophozoitesS F Freitas
Department of Parasitology, Biosciences Institute, IB-UNESP, Botucatu, SP, Brazil
Phytomedicine 13:170-5. 2006..Our results hold the perspective for the utilization of propolis as an antigiardial agent...
Radionuclides in honeybee propolis (Apis mellifera L.)R O Orsi
Department of Production and Animal Exploration, School of Veterinary Medicine and Animal Husbandry, , Botucatu, , Brazil
Bull Environ Contam Toxicol 76:637-40. 2006
