Maria N Sato
de Carvalho G, Hirata F, Domingues R, Figueiredo C, Zaniboni M, Pereira N, et al
. Up-regulation of HMGB1 and TLR4 in skin lesions of lichen planus. Arch Dermatol Res. 2018;310:523-528 pubmed publisher
..Similar HMGB1 serum levels were detected in the LP and control groups. This study demonstrates that HMGB1 and TLR4 could contribute to the inflammatory LP process in skin. ..
de Lollo C, De Moraes Vasconcelos D, da Silva Oliveira L, de Oliveira Titz T, Carneiro Sampaio M, Jacob C, et al
. Impaired CD8(+) T cell responses upon Toll-like receptor activation in common variable immunodeficiency. J Transl Med. 2016;14:138 pubmed publisher
Domingues R, de Carvalho G, Aoki V, da Silva Duarte A, Sato M. Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus. J Transl Med. 2016;14:171 pubmed publisher
..Therefore, TLR activation has an adjuvant role in inducing both innate and adaptive immune responses. ..
Lollo C, De Moraes Vasconcelos D, Oliveira L, Domingues R, Carvalho G, Duarte A, et al
. Chemokine, cytokine and type I interferon production induced by Toll-like receptor activation in common variable immune deficiency. Clin Immunol. 2016;169:121-127 pubmed publisher
..Decreased IFN-? secretion induced by TLR7/TLR8 activation was observed in CVID, which was recovered with TLR9 signaling. Our findings revealed that TLR9 activation has an adjuvant effect on the altered type I response in CVID. ..
Lima J, Oliveira L, Pereira N, Duarte A, Sato M. Polyfunctional natural killer cells with a low activation profile in response to Toll-like receptor 3 activation in HIV-1-exposed seronegative subjects. Sci Rep. 2017;7:524 pubmed publisher