Norma Santos

Summary

Affiliation: Rio de Janeiro
Country: Brazil

Publications

  1. doi request reprint Polymorphism of rotavirus genotype G1 in Brazil: in silico analysis of variant strains circulating in Rio de Janeiro from 1996 to 2004
    Adriana Gonçalves Maranhão
    Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Infect Genet Evol 12:1397-404. 2012
  2. pmc Development of a microtiter plate hybridization-based PCR-enzyme-linked immunosorbent assay for identification of clinically relevant human group A rotavirus G and P genotypes
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro 21 941 590, Brazil
    J Clin Microbiol 46:462-9. 2008
  3. pmc Predominance of rotavirus genotype G9 during the 1999, 2000, and 2002 seasons among hospitalized children in the city of Salvador, Bahia, Brazil: implications for future vaccine strategies
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21 941 590, Brazil
    J Clin Microbiol 43:4064-9. 2005
  4. ncbi request reprint Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21 941 590, Brazil
    Rev Med Virol 15:29-56. 2005
  5. doi request reprint Human bocavirus species 2 and 3 in Brazil
    Norma Santos
    Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941 590, Brazil
    J Clin Virol 48:127-30. 2010
  6. pmc Surveillance of rotavirus strains in Rio de Janeiro, Brazil, from 1997 to 1999
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21 941 590, Brazil
    J Clin Microbiol 41:3399-402. 2003
  7. ncbi request reprint VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCR
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro, RJ 21 941 590, Brazil
    Virus Res 93:127-38. 2003
  8. ncbi request reprint VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCR
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, RJ 21 941 590, Rio de Janeiro, Brazil
    Virus Res 90:1-14. 2002
  9. pmc Genotyping of enteric adenoviruses by using single-stranded conformation polymorphism analysis and heteroduplex mobility assay
    Caroline C Soares
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941 590, Brazil
    J Clin Microbiol 42:1723-6. 2004
  10. pmc Human bocavirus infection in children with gastroenteritis, Brazil
    Maria Carolina M Albuquerque
    Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Emerg Infect Dis 13:1756-8. 2007

Collaborators

  • Maria Carolina M Albuquerque
  • Caroline C Soares
  • Yasutaka Hoshino
  • Roger I Glass
  • Carla Martins
  • Hiroshi Ushijima
  • Stephan S Monroe
  • Sonia Soares Costa
  • Jon R Gentsch
  • George E Armah
  • Miguel L O'Ryan
  • D D Erdman
  • A C Linhares
  • Dmitriy V Volokhov
  • Rafael Brandão Varella
  • A Z Kapikian
  • Osamu Nakagomi
  • Ricardo Q Gurgel
  • Fabrício José Benati
  • Adriana G Maranhão
  • Raquel C Silva
  • Eduardo M Volotão
  • Tatiana F Robaina
  • Danielle P Oliveira-Batista
  • Maria Elisa R Janini
  • Adriana Gonçalves Maranhão
  • Nurimar C Fernandes
  • Fabricio J Benati
  • Flávio Lauretti
  • Renata Otero
  • Gabriella Mendes
  • Maria Luiza Figueiredo Braga Brandão
  • Angelica Ribeiro Soares
  • Maria Teresa Villela Romanos
  • Gabriella da Silva Mendes
  • Fabricio Benati
  • Dianjun Cao
  • Masatoshi Tatsumi
  • Karina Serravalle
  • Shinjiro Honma
  • Eduardo Pietruchinski
  • Carlos Nozawa
  • Maria Carolina Maciel de Albuquerque
  • Fernando P Câmara
  • Giselle A Pena
  • Miguel A R Montes
  • Gabriella S Mendes
  • João Lídio S G Vianez-Júnior
  • Paulo Mascarello Bisch
  • Lísia Gestinari
  • Nelilma Romeiro
  • Gloria Castro
  • Lorena Sigiliano
  • Carlos Kaiser
  • Fernanda Machado
  • Danielle Pereira De Oliveira Batista
  • Dennis Ferreira
  • Giselle P A Pena
  • Lísia Mônica de Souza Gestinari
  • Raquel Cirlene da Silva
  • Rodrigo S Lima
  • Fernanda Otaviano Martins
  • Yocie Yoneshigue-Valentin
  • Ronald W Jones
  • Hugo da Costa Ribeiro Junior
  • Gubio Soares Campos
  • Maria do Carmo S T Timenetsky
  • Sarah Peregrino Santos Silva
  • Vladimir Chizhikov
  • Angela Peixoto de Mattos
  • Silvia Ines Sardi
  • Ludmila N Rocha
  • Jonas Kisielius
  • Rosa Elisa C Linhares
  • Marli Ueda
  • Eduardo de Mello Volotao
  • Rosa Elisa Carvalho Linhares
  • Eduardo de Mello Volotão
  • Fabiano Murga da Silva
  • Fernando Lucas de Melo

Detail Information

Publications35

  1. doi request reprint Polymorphism of rotavirus genotype G1 in Brazil: in silico analysis of variant strains circulating in Rio de Janeiro from 1996 to 2004
    Adriana Gonçalves Maranhão
    Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Infect Genet Evol 12:1397-404. 2012
    ..Consequently, continuous monitoring of rotavirus intragenotypes diversity is critical to understand how it could affect vaccine effectiveness...
  2. pmc Development of a microtiter plate hybridization-based PCR-enzyme-linked immunosorbent assay for identification of clinically relevant human group A rotavirus G and P genotypes
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro 21 941 590, Brazil
    J Clin Microbiol 46:462-9. 2008
    ....
  3. pmc Predominance of rotavirus genotype G9 during the 1999, 2000, and 2002 seasons among hospitalized children in the city of Salvador, Bahia, Brazil: implications for future vaccine strategies
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21 941 590, Brazil
    J Clin Microbiol 43:4064-9. 2005
    ..The next generation of rotavirus vaccines will need to provide adequate protection against disease caused by G9 viruses...
  4. ncbi request reprint Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21 941 590, Brazil
    Rev Med Virol 15:29-56. 2005
    ..g. a geographical P-G type adjustment in the formulation of next generation multivalent vaccines)...
  5. doi request reprint Human bocavirus species 2 and 3 in Brazil
    Norma Santos
    Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941 590, Brazil
    J Clin Virol 48:127-30. 2010
    ....
  6. pmc Surveillance of rotavirus strains in Rio de Janeiro, Brazil, from 1997 to 1999
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21 941 590, Brazil
    J Clin Microbiol 41:3399-402. 2003
    ..Genotypes G9P[8], G9P[6], and a mixture of G9 and other G or P types represented 15.9% (25 of 157) of the isolates. Mixed infections were detected in 25 (15.9%) samples, and rotaviruses in 15 samples (9.6%) were not typed...
  7. ncbi request reprint VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCR
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro, RJ 21 941 590, Brazil
    Virus Res 93:127-38. 2003
    ....
  8. ncbi request reprint VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCR
    Norma Santos
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, RJ 21 941 590, Rio de Janeiro, Brazil
    Virus Res 90:1-14. 2002
    ..the magnitude of difference in nucleotide homology at respective primer binding site between homotypic (G9) and heterotypic (G3 or G4) primers present in a primer pool employed...
  9. pmc Genotyping of enteric adenoviruses by using single-stranded conformation polymorphism analysis and heteroduplex mobility assay
    Caroline C Soares
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941 590, Brazil
    J Clin Microbiol 42:1723-6. 2004
    ..Of the 31 stool samples tested, 15 isolates were identified as EAd and 7 were identified as nonenteric Ad by all methods. An agreement of 100% was found between the SSCP and HMA results...
  10. pmc Human bocavirus infection in children with gastroenteritis, Brazil
    Maria Carolina M Albuquerque
    Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Emerg Infect Dis 13:1756-8. 2007
    ..Coinfection with rotavirus, adenovirus, or norovirus was found in 3 (21.4%) HBoV-positive specimens. None of the HBoV-positive patients had respiratory symptoms...
  11. doi request reprint Multiple-gene characterization of rotavirus strains: evidence of genetic linkage among the VP7-, VP4-, VP6-, and NSP4-encoding genes
    Fabrício José Benati
    Microbiology Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
    J Med Virol 82:1797-802. 2010
    ..3%) strains. The characterization of multiple genes allows a more complete analysis of the rotavirus isolates and provides evidence of natural reassortment of strains...
  12. ncbi request reprint Molecular epidemiology of adenovirus conjunctivitis in Rio de Janeiro, Brazil, between 2004 and 2007
    Adriana G Maranhão
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    Rev Inst Med Trop Sao Paulo 51:227-9. 2009
    ..7%), 7 AdV8 (15.5%), 3 AdV31 (6.7%), and one each AdV1, AdV2, AdV3, AdV4 and AdV6. For nine samples the serotype was not determined. AdV19 was the predominant serotype circulating in Rio de Janeiro during the studied period...
  13. ncbi request reprint Rotavirus surveillance in the city of Rio de Janeiro-Brazil during 2000-2004: detection of unusual strains with G8P[4] or G10P[9] specificities
    Eduardo M Volotão
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    J Med Virol 78:263-72. 2006
    ..Two samples (1.6%) presented mixed P genotypes (P[6] + P[8]). Two unusual strains were isolated: a G8P[4] strain isolated from a non-hospitalized child with diarrhea and a G10P[9] strain isolated from a hospitalized child with diarrhea...
  14. ncbi request reprint Prevalence of enteric adenoviruses among children with diarrhea in four Brazilian cities
    Caroline C Soares
    Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, IIha do Fundão, RJ, 21 941 590, Rio de Janeiro, Brazil
    J Clin Virol 23:171-7. 2002
    ..Enteric adenoviruses are related to child diarrhea and appear to be spread worldwide...
  15. pmc Norovirus detection and genotyping for children with gastroenteritis, Brazil
    Caroline C Soares
    Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Emerg Infect Dis 13:1244-6. 2007
    ..Previous tests showed all samples to be negative for rotavirus and adenovirus. Of 42 (14.5%) no-rovirus-positive specimens, 20 (47.6%) were identified as genogroup GI and 22 (52.3%) as GII...
  16. doi request reprint In vitro anti-HMPV activity of meroditerpenoids from marine alga Stypopodium zonale (Dictyotales)
    Gabriella Mendes
    Laboratório Experimental de Drogas Antivirais e Citotóxicas LEDAC, Departamento de Virologia do, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro UFRJ, CCS, Bloco I, Caixa Postal 68040, 21941 590 Rio de Janeiro, RJ, Brasil
    Molecules 16:8437-50. 2011
    ....
  17. ncbi request reprint Astrovirus detection in sporadic cases of diarrhea among hospitalized and non-hospitalized children in Rio De Janeiro, Brazil, from 1998 to 2004
    Caroline Cordeiro Soares
    Department of Virology, Institute of Microbiology, Universidade Federal do Rio de Janeiro, Rio de Janiero, Brazil
    J Med Virol 80:113-7. 2008
    ..The study documented that astrovirus is an agent of acute diarrhea in children who are inpatients or outpatients in Rio de Janeiro, Brazil although it seems to be less common as a single cause of childhood diarrhea then rotavirus...
  18. ncbi request reprint Molecular characterization of viruses associated with gastrointestinal infection in HIV-positive patients
    Raquel C Silva
    Department of Virology, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Brazil
    Braz J Infect Dis 14:549-52. 2010
    ..Diarrhea is a major cause of morbidity and mortality among HIV-infected patients worldwide...
  19. ncbi request reprint Acute respiratory viral infections in children in Rio de Janeiro and Teresópolis, Brazil
    Maria Carolina M Albuquerque
    Departament of Virology, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    Rev Inst Med Trop Sao Paulo 54:249-55. 2012
    ..The fact that the emerging respiratory viruses were present in 9.2% of the tested samples suggests that these viruses could be important respiratory pathogens in the country...
  20. pmc Novel respiratory virus infections in children, Brazil
    Maria Carolina M Albuquerque
    Universidade Federal do Rio de Janeiro, Brazil
    Emerg Infect Dis 15:806-8. 2009
    ..Five each were positive for human metapneumovirus (HMPV) alone and human bocavirus (HBoV) alone, 3 for human coronaviruses (HCoV-HKU1 or -NL63) alone, and 6 for more than 1 recently discovered virus...
  21. doi request reprint Shedding of polyomavirus in the saliva of immunocompetent individuals
    Tatiana F Robaina
    Microbiology Institute, Federal University of Rio of Janeiro, Rio de Janeiro, RJ, Brazil
    J Med Virol 85:144-8. 2013
    ..These data also demonstrated that JCV, WUV, and KIV may be transmitted in a similar fashion...
  22. doi request reprint Identification of herpesvirus types 1-8 in oral cavity of children/adolescents with chronic renal failure
    Renata Otero
    Department of Pediatric Dentistry Department of Microbiology, Universidade Federal do Rio de Janeiro, RJ, Brazil
    J Oral Pathol Med 40:610-5. 2011
    ..So, more attention should be paid to the oral health of these individuals in order to prevent infection by opportunistic pathogens...
  23. doi request reprint Laboratory diagnosis of herpesvirus infections in patients with Pemphigus vulgaris lesions
    Danielle P Oliveira-Batista
    Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Intervirology 56:231-6. 2013
    ..This study investigates the frequency of herpesvirus infections in patients with PV lesions...
  24. ncbi request reprint Adenoviruses isolated from civilian and military personnel in the city of Rio de Janeiro, Brazil
    Maria Carolina Maciel de Albuquerque
    Departamento de Virologia, Instituto de Microbiologia Prof Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941 590, Brazil
    Rev Inst Med Trop Sao Paulo 45:233-6. 2003
    ..For two isolates the specie could not be identified...
  25. ncbi request reprint Refractory pemphigus vulgaris associated with herpes infection: case report and review
    Maria Luiza Figueiredo Braga Brandão
    Departamento de Dermatologia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    Rev Inst Med Trop Sao Paulo 53:113-7. 2011
    ..Infections caused by members of the Herpesviridae family have been suggested as a possible triggering factor for PV...
  26. ncbi request reprint Antiviral activity of the green marine alga Ulva fasciata on the replication of human metapneumovirus
    Gabriella da Silva Mendes
    Departamento de Virologia, Instituto de Microbiologia Prof Paulo de Goes, Universidade Federal do Rio de Janeiro, Brasil
    Rev Inst Med Trop Sao Paulo 52:3-10. 2010
    ..It is also the first on antiviral activity against HMPV ever done in Brazil. The study also shows the effect of different environment factors and different chemical procedures used to obtain the extract on its biological properties...
  27. ncbi request reprint Use of acridine orange staining for the detection of rotavirus RNA in polyacrylamide gels
    Flávio Lauretti
    Departamento de Microbiologia, Centro de Ciencias Biologicas, Universidade Estadual de Londrina, CEP 86051 900, Londrina, Parana, Brazil
    J Virol Methods 114:29-35. 2003
    ..It is suggested the use of acridine orange as an appropriate stain for various purposes in virology, as well as for the molecular biology of nucleic acid...
  28. ncbi request reprint Human rotavirus strains bearing VP4 gene P[6] allele recovered from asymptomatic or symptomatic infections share similar, if not identical, VP4 neutralization specificities
    Yasutaka Hoshino
    Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
    Virology 316:1-8. 2003
    ..In addition, a close VP4 serotypic relationship between human P[6] rotavirus strains and the porcine P[6] rotavirus Gottfried strain was confirmed...
  29. pmc Rotavirus serotype G9 strains belonging to VP7 gene phylogenetic sequence lineage 1 may be more suitable for serotype G9 vaccine candidates than those belonging to lineage 2 or 3
    Yasutaka Hoshino
    Laboratory of Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
    J Virol 78:7795-802. 2004
    ..These findings may have important implications for the development of G9 rotavirus vaccine candidates, as the strain with the broadest reactivity (i.e., a prime strain) would certainly be the ideal strain for inclusion in a vaccine...
  30. pmc The VP7 genes of two G9 rotaviruses isolated in 1980 from diarrheal stool samples collected in Washington, DC, are unique molecularly and serotypically
    Dianjun Cao
    Epidemiology Section, Laboratory of Infectious Diseases, NIAID, NIH, Building 50, Room 6308, Bethesda, MD 20902, USA
    J Virol 82:4175-9. 2008
    ..Unexpectedly, however, the VP7s of the 1980 G9 viruses were more closely related serotypically to lineage 3 VP7s than to lineage 2 VP7, which may be supported by amino acid sequence analyses of the VP7 proteins...
  31. ncbi request reprint A porcine G9 rotavirus strain shares neutralization and VP7 phylogenetic sequence lineage 3 characteristics with contemporary human G9 rotavirus strains
    Yasutaka Hoshino
    Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 50, Room 6308, 50 South Drive MSC 8026, Bethesda, MD 20892 8026, USA
    Virology 332:177-88. 2005
    ..Furthermore, by sequence analysis, the A2 VP7 was shown to belong to lineage 3 G9. These findings raise intriguing questions regarding possible explanations for the emergence of variations among the G9 strains...
  32. ncbi request reprint A rotavirus strain isolated from pig-tailed macaque (Macaca nemestrina) with diarrhea bears a P6[1]:G8 specificity
    Yasutaka Hoshino
    Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
    Virology 345:1-12. 2006
    ..Because of its unique simian serotype, this virus may prove to be valuable in challenge studies in a non-human primate model in studies of rotavirus immunity...
  33. ncbi request reprint Rotavirus diarrhea in children and adults in a southern city of Brazil in 2003: distribution of G/P types and finding of a rare G12 strain
    Eduardo Pietruchinski
    Departamento de Microbiologia, Centro de Ciencias Biologicas, Universidade Estadual de Londrina, Londrina, PR, Brazil
    J Med Virol 78:1241-9. 2006
    ..The cell-culture grown HC91 strain was shown to belong to serotype G12 by neutralization...
  34. ncbi request reprint Molecular characterization of group A rotavirus isolates obtained from hospitalized children in Salvador, Bahia, Brazil
    Karina Serravalle
    Laboratory of Virology, Institute of Science Health, Federal University of Bahia, Salvador, BA, Brazil
    Braz J Infect Dis 11:35-9. 2007
    ..In this study we discuss the benefit to control the genotypes of Rotavirus through the molecular characterization for the development of potential vaccines...
  35. pmc Development and validation of DNA microarray for genotyping group A rotavirus VP4 (P[4], P[6], P[8], P[9], and P[14]) and VP7 (G1 to G6, G8 to G10, and G12) genes
    Shinjiro Honma
    Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 8026, USA
    J Clin Microbiol 45:2641-8. 2007
    ..Moreover, because the hybridization patterns exhibited by rotavirus strains of different genotypes can vary, this method may be ideal for analyzing the genetic polymorphisms of the VP7 or VP4 genes of rotaviruses...