Research Topics
| Norma SantosSummaryAffiliation: Rio de Janeiro Country: Brazil Publications
| Collaborators
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Detail Information
Publications
Polymorphism of rotavirus genotype G1 in Brazil: in silico analysis of variant strains circulating in Rio de Janeiro from 1996 to 2004Adriana Gonçalves Maranhão
Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Infect Genet Evol 12:1397-404. 2012..Consequently, continuous monitoring of rotavirus intragenotypes diversity is critical to understand how it could affect vaccine effectiveness...
Development of a microtiter plate hybridization-based PCR-enzyme-linked immunosorbent assay for identification of clinically relevant human group A rotavirus G and P genotypesNorma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro 21 941 590, Brazil
J Clin Microbiol 46:462-9. 2008....- Predominance of rotavirus genotype G9 during the 1999, 2000, and 2002 seasons among hospitalized children in the city of Salvador, Bahia, Brazil: implications for future vaccine strategiesNorma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21 941 590, Brazil
J Clin Microbiol 43:4064-9. 2005..The next generation of rotavirus vaccines will need to provide adequate protection against disease caused by G9 viruses... 
Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccineNorma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21 941 590, Brazil
Rev Med Virol 15:29-56. 2005..g. a geographical P-G type adjustment in the formulation of next generation multivalent vaccines)...- Human bocavirus species 2 and 3 in BrazilNorma Santos
Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941 590, Brazil
J Clin Virol 48:127-30. 2010.... - Surveillance of rotavirus strains in Rio de Janeiro, Brazil, from 1997 to 1999Norma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ 21 941 590, Brazil
J Clin Microbiol 41:3399-402. 2003..Genotypes G9P[8], G9P[6], and a mixture of G9 and other G or P types represented 15.9% (25 of 157) of the isolates. Mixed infections were detected in 25 (15.9%) samples, and rotaviruses in 15 samples (9.6%) were not typed... - VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCRNorma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, Rio de Janeiro, RJ 21 941 590, Brazil
Virus Res 93:127-38. 2003.... - VP7 gene polymorphism of serotype G9 rotavirus strains and its impact on G genotype determination by PCRNorma Santos
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Cidade Universitaria, CCS Bl I, Ilha do Fundao, RJ 21 941 590, Rio de Janeiro, Brazil
Virus Res 90:1-14. 2002..the magnitude of difference in nucleotide homology at respective primer binding site between homotypic (G9) and heterotypic (G3 or G4) primers present in a primer pool employed... - Genotyping of enteric adenoviruses by using single-stranded conformation polymorphism analysis and heteroduplex mobility assayCaroline C Soares
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil
J Clin Microbiol 42:1723-6. 2004..Of the 31 stool samples tested, 15 isolates were identified as EAd and 7 were identified as nonenteric Ad by all methods. An agreement of 100% was found between the SSCP and HMA results... - Human bocavirus infection in children with gastroenteritis, BrazilMaria Carolina M Albuquerque
Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Emerg Infect Dis 13:1756-8. 2007..Coinfection with rotavirus, adenovirus, or norovirus was found in 3 (21.4%) HBoV-positive specimens. None of the HBoV-positive patients had respiratory symptoms... - Multiple-gene characterization of rotavirus strains: evidence of genetic linkage among the VP7-, VP4-, VP6-, and NSP4-encoding genesFabrício José Benati
Microbiology Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
J Med Virol 82:1797-802. 2010..3%) strains. The characterization of multiple genes allows a more complete analysis of the rotavirus isolates and provides evidence of natural reassortment of strains... - Rotavirus surveillance in the city of Rio de Janeiro-Brazil during 2000-2004: detection of unusual strains with G8P[4] or G10P[9] specificitiesEduardo M Volotão
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
J Med Virol 78:263-72. 2006..Two samples (1.6%) presented mixed P genotypes (P[6] + P[8]). Two unusual strains were isolated: a G8P[4] strain isolated from a non-hospitalized child with diarrhea and a G10P[9] strain isolated from a hospitalized child with diarrhea... - Molecular epidemiology of adenovirus conjunctivitis in Rio de Janeiro, Brazil, between 2004 and 2007Adriana G Maranhão
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Inst Med Trop Sao Paulo 51:227-9. 2009..7%), 7 AdV8 (15.5%), 3 AdV31 (6.7%), and one each AdV1, AdV2, AdV3, AdV4 and AdV6. For nine samples the serotype was not determined. AdV19 was the predominant serotype circulating in Rio de Janeiro during the studied period... - Norovirus detection and genotyping for children with gastroenteritis, BrazilCaroline C Soares
Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Emerg Infect Dis 13:1244-6. 2007..Previous tests showed all samples to be negative for rotavirus and adenovirus. Of 42 (14.5%) no-rovirus-positive specimens, 20 (47.6%) were identified as genogroup GI and 22 (52.3%) as GII... - Prevalence of enteric adenoviruses among children with diarrhea in four Brazilian citiesCaroline C Soares
Departamento de Virologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, , CCS-Bl. I, , RJ, 21.941-590, Rio de Janeiro, Brazil
J Clin Virol 23:171-7. 2002..These agents were isolated throughout the year demonstrating no specific seasonal distribution. Also, no pattern of serotype distribution between the cities was observed... - Astrovirus detection in sporadic cases of diarrhea among hospitalized and non-hospitalized children in Rio De Janeiro, Brazil, from 1998 to 2004Caroline Cordeiro Soares
Department of Virology, Institute of Microbiology, Universidade Federal do Rio de Janeiro, Rio de Janiero, Brazil
J Med Virol 80:113-7. 2008..The study documented that astrovirus is an agent of acute diarrhea in children who are inpatients or outpatients in Rio de Janeiro, Brazil although it seems to be less common as a single cause of childhood diarrhea then rotavirus... - In vitro anti-HMPV activity of meroditerpenoids from marine alga Stypopodium zonale (Dictyotales)Gabriella Mendes
Laboratório Experimental de Drogas Antivirais e Citotóxicas LEDAC, Departamento de Virologia do, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro UFRJ, CCS, Bloco I, Caixa Postal 68040, 21941 590 Rio de Janeiro, RJ, Brasil
Molecules 16:8437-50. 2011.... - Molecular characterization of viruses associated with gastrointestinal infection in HIV-positive patientsRaquel C Silva
Department of Virology, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Brazil
Braz J Infect Dis 14:549-52. 2010..Diarrhea is a major cause of morbidity and mortality among HIV-infected patients worldwide... - Acute respiratory viral infections in children in Rio de Janeiro and Teresópolis, BrazilMaria Carolina M Albuquerque
Departament of Virology, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
Rev Inst Med Trop Sao Paulo 54:249-55. 2012..The fact that the emerging respiratory viruses were present in 9.2% of the tested samples suggests that these viruses could be important respiratory pathogens in the country... - Novel respiratory virus infections in children, BrazilMaria Carolina M Albuquerque
Universidade Federal do Rio de Janeiro, Brazil
Emerg Infect Dis 15:806-8. 2009..Five each were positive for human metapneumovirus (HMPV) alone and human bocavirus (HBoV) alone, 3 for human coronaviruses (HCoV-HKU1 or -NL63) alone, and 6 for more than 1 recently discovered virus... - Shedding of polyomavirus in the saliva of immunocompetent individualsTatiana F Robaina
Microbiology Institute, Federal University of Rio of Janeiro, Rio de Janeiro, RJ, Brazil
J Med Virol 85:144-8. 2013..These data also demonstrated that JCV, WUV, and KIV may be transmitted in a similar fashion... - Identification of herpesvirus types 1-8 in oral cavity of children/adolescents with chronic renal failureRenata Otero
Department of Pediatric Dentistry Department of Microbiology, Universidade Federal do Rio de Janeiro, RJ, Brazil
J Oral Pathol Med 40:610-5. 2011..So, more attention should be paid to the oral health of these individuals in order to prevent infection by opportunistic pathogens... - Adenoviruses isolated from civilian and military personnel in the city of Rio de Janeiro, BrazilMaria Carolina Maciel de Albuquerque
Departamento de Virologia, , Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-590, Brazil
Rev Inst Med Trop Sao Paulo 45:233-6. 2003..For two isolates the specie could not be identified... - Refractory pemphigus vulgaris associated with herpes infection: case report and reviewMaria Luiza Figueiredo Braga Brandão
Departamento de Dermatologia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil
Rev Inst Med Trop Sao Paulo 53:113-7. 2011..Infections caused by members of the Herpesviridae family have been suggested as a possible triggering factor for PV... - Antiviral activity of the green marine alga Ulva fasciata on the replication of human metapneumovirusGabriella da Silva Mendes
Departamento de Virologia, Instituto de Microbiologia Prof Paulo de Goes, Universidade Federal do Rio de Janeiro, Brasil
Rev Inst Med Trop Sao Paulo 52:3-10. 2010..It is also the first on antiviral activity against HMPV ever done in Brazil. The study also shows the effect of different environment factors and different chemical procedures used to obtain the extract on its biological properties... - Human rotavirus strains bearing VP4 gene P[6] allele recovered from asymptomatic or symptomatic infections share similar, if not identical, VP4 neutralization specificitiesYasutaka Hoshino
Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
Virology 316:1-8. 2003..In addition, a close VP4 serotypic relationship between human P[6] rotavirus strains and the porcine P[6] rotavirus Gottfried strain was confirmed... - Use of acridine orange staining for the detection of rotavirus RNA in polyacrylamide gelsFlávio Lauretti
Departamento de Microbiologia, Centro de Ciencias Biologicas, Universidade Estadual de Londrina, CEP 86051 900, Londrina, Parana, Brazil
J Virol Methods 114:29-35. 2003..It is suggested the use of acridine orange as an appropriate stain for various purposes in virology, as well as for the molecular biology of nucleic acid... - Rotavirus serotype G9 strains belonging to VP7 gene phylogenetic sequence lineage 1 may be more suitable for serotype G9 vaccine candidates than those belonging to lineage 2 or 3Yasutaka Hoshino
Laboratory of Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
J Virol 78:7795-802. 2004..These findings may have important implications for the development of G9 rotavirus vaccine candidates, as the strain with the broadest reactivity (i.e., a prime strain) would certainly be the ideal strain for inclusion in a vaccine... - The VP7 genes of two G9 rotaviruses isolated in 1980 from diarrheal stool samples collected in Washington, DC, are unique molecularly and serotypicallyDianjun Cao
Epidemiology Section, Laboratory of Infectious Diseases, NIAID, NIH, Building 50, Room 6308, Bethesda, MD 20902, USA
J Virol 82:4175-9. 2008..Unexpectedly, however, the VP7s of the 1980 G9 viruses were more closely related serotypically to lineage 3 VP7s than to lineage 2 VP7, which may be supported by amino acid sequence analyses of the VP7 proteins... - A porcine G9 rotavirus strain shares neutralization and VP7 phylogenetic sequence lineage 3 characteristics with contemporary human G9 rotavirus strainsYasutaka Hoshino
Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 50, Room 6308, 50 South Drive MSC 8026, Bethesda, MD 20892 8026, USA
Virology 332:177-88. 2005..Furthermore, by sequence analysis, the A2 VP7 was shown to belong to lineage 3 G9. These findings raise intriguing questions regarding possible explanations for the emergence of variations among the G9 strains... - A rotavirus strain isolated from pig-tailed macaque (Macaca nemestrina) with diarrhea bears a P6[1]:G8 specificityYasutaka Hoshino
Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 8026, USA
Virology 345:1-12. 2006..Because of its unique simian serotype, this virus may prove to be valuable in challenge studies in a non-human primate model in studies of rotavirus immunity... - Rotavirus diarrhea in children and adults in a southern city of Brazil in 2003: distribution of G/P types and finding of a rare G12 strainEduardo Pietruchinski
Departamento de Microbiologia, , Universidade Estadual de Londrina, Londrina, PR, Brazil
J Med Virol 78:1241-9. 2006..The cell-culture grown HC91 strain was shown to belong to serotype G12 by neutralization... - Molecular characterization of group A rotavirus isolates obtained from hospitalized children in Salvador, Bahia, BrazilKarina Serravalle
Laboratory of Virology, Institute of Science Health, Federal University of Bahia, Salvador, BA, Brazil
Braz J Infect Dis 11:35-9. 2007..In this study we discuss the benefit to control the genotypes of Rotavirus through the molecular characterization for the development of potential vaccines... - Development and validation of DNA microarray for genotyping group A rotavirus VP4 (P[4], P[6], P[8], P[9], and P[14]) and VP7 (G1 to G6, G8 to G10, and G12) genesShinjiro Honma
Epidemiology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 8026, USA
J Clin Microbiol 45:2641-8. 2007..Moreover, because the hybridization patterns exhibited by rotavirus strains of different genotypes can vary, this method may be ideal for analyzing the genetic polymorphisms of the VP7 or VP4 genes of rotaviruses...