Leila Mendonça-Lima

Summary

Affiliation: Rio de Janeiro
Country: Brazil

Publications

  1. pmc A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology
    Patrícia M Ferrão
    Laboratório de Genômica Funcional e Bioinformática, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil
    PLoS ONE 7:e38736. 2012
  2. pmc Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis
    Alessandra F Gomes
    Laboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Av, Brasil 4365, Rio de Janeiro 21040 361, Brazil
    BMC Microbiol 11:110. 2011
  3. pmc Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion
    Mariana C Waghabi
    Laboratorios de Biologia Celular, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil
    Am J Pathol 167:993-1003. 2005
  4. pmc Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis
    Leonardo H F Gomes
    Laboratório de Genômica Funcional e Bioinformática, Pavilhão Leonidas Deane sala 104, Instituto Oswaldo Cruz, Fiocruz Av, Brasil 4365, Manguinhos, 21040 900 Rio de Janeiro, Brazil
    J Bacteriol 193:5600-1. 2011
  5. pmc SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion
    Mariana C Waghabi
    Laboratório de Genômica Funcional e Bioinformática, Departamento de Bioquimica e Biologia Molecular, Instituto Oswaldo Cruz, Brasil, Rio de Janeiro, RJ, Brazil
    Antimicrob Agents Chemother 51:2905-10. 2007
  6. ncbi Kinetoplastid membrane protein-11 exacerbates infection with Leishmania amazonensis in murine macrophages
    Daniel Ignacchiti Lacerda
    Laboratorio de Imunoparasitologia, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 107:238-45. 2012
  7. doi Proteomic characterization of the released/secreted proteins of Leishmania (Viannia) braziliensis promastigotes
    Patricia Cuervo
    Laboratorio de Pesquisa em Leishmaniose, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil
    J Proteomics 73:79-92. 2009
  8. pmc Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur
    Marcia Berrêdo-Pinho
    Laboratório de Genômica Funcional e Bioinformática, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, CEP 21040 900 Rio de Janeiro, RJ, Brazil
    BMC Microbiol 11:80. 2011

Collaborators

  • Leonardo Saboia-Vahia
  • Jose B De Jesus
  • Elisa Cupolillo
  • Mariana C Waghabi
  • Patrícia M Ferrão
  • Wim M Degrave
  • Marcia Berrêdo-Pinho
  • Leonardo H F Gomes
  • Tania C Araujo-Jorge
  • Daniel Ignacchiti Lacerda
  • Luiz R R Castello-Branco
  • Alessandra F Gomes
  • Patricia Cuervo
  • Michelle Keramidas
  • Maria de Nazaré C Soeiro
  • Sabine Bailly
  • Jean Jacques Feige
  • Fabiane L de Oliveira
  • Marco Alberto Medeiros
  • Lea Cysne-Finkelstein
  • Marise Pinheiro Nunes
  • Denise Cristina de Souza Matos
  • Leonor Laura Pinto Leon
  • Sergio Coutinho Furtado de Mendonça
  • Marcelo da Silva Genestra
  • Paula Mello De-Luca
  • José R Corrêa
  • Aline S Moreira
  • Helene S Barbosa
  • Renata F da Silva
  • Laís Carvalho
  • Marcelo A Ferreira
  • Erick V Guimarães
  • Melissa P Pereira
  • Erico A Vasconcellos
  • Thomas D Otto
  • Renata M Maia
  • Dario E Kalume
  • Paloma R Correa
  • Gilberto B Domont
  • Marcos Meuser
  • Claudia M Calvet
  • Sidnei Paciornik
  • Wim Degrave
  • Maria de Nazareth L Meirelles

Detail Information

Publications8

  1. pmc A phosphoproteomic approach towards the understanding of the role of TGF-β in Trypanosoma cruzi biology
    Patrícia M Ferrão
    Laboratório de Genômica Funcional e Bioinformática, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil
    PLoS ONE 7:e38736. 2012
    ..In our study, we observed that TGF-β addition favored epimastigote proliferation, corroborating 2DE data in which proteins previously described to be involved in this process were positively stimulated by TGF-β...
  2. pmc Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis
    Alessandra F Gomes
    Laboratório de Biologia Estrutural, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Av, Brasil 4365, Rio de Janeiro 21040 361, Brazil
    BMC Microbiol 11:110. 2011
    ..The myogenesis of SkMC was reproduced in vitro and the ability of T. gondii tachyzoite forms to infect myoblasts and myotubes and its influence on SkMC myogenesis were analyzed...
  3. pmc Uptake of host cell transforming growth factor-beta by Trypanosoma cruzi amastigotes in cardiomyocytes: potential role in parasite cycle completion
    Mariana C Waghabi
    Laboratorios de Biologia Celular, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil
    Am J Pathol 167:993-1003. 2005
    ..These observations represent the first example of a novel mechanism by which a primitive unicellular protozoan can use host cell TGF-beta to control its own intracellular life cycle...
  4. pmc Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis
    Leonardo H F Gomes
    Laboratório de Genômica Funcional e Bioinformática, Pavilhão Leonidas Deane sala 104, Instituto Oswaldo Cruz, Fiocruz Av, Brasil 4365, Manguinhos, 21040 900 Rio de Janeiro, Brazil
    J Bacteriol 193:5600-1. 2011
    ..Here we report the complete genome sequence of M. bovis BCG Moreau, the strain in continuous use in Brazil for vaccine production since the 1920s...
  5. pmc SB-431542, a transforming growth factor beta inhibitor, impairs Trypanosoma cruzi infection in cardiomyocytes and parasite cycle completion
    Mariana C Waghabi
    Laboratório de Genômica Funcional e Bioinformática, Departamento de Bioquimica e Biologia Molecular, Instituto Oswaldo Cruz, Brasil, Rio de Janeiro, RJ, Brazil
    Antimicrob Agents Chemother 51:2905-10. 2007
    ..cruzi infection and T. cruzi cell cycle completion. Our present data demonstrate that small inhibitors of the TGF-beta signaling pathway might be potential pharmacological tools for the treatment of Chagas disease...
  6. ncbi Kinetoplastid membrane protein-11 exacerbates infection with Leishmania amazonensis in murine macrophages
    Daniel Ignacchiti Lacerda
    Laboratorio de Imunoparasitologia, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 107:238-45. 2012
    ..amazonensis. The stimulation of IL-10 production and arginase activity and the inhibition of NO synthesis are likely involved in this effect...
  7. doi Proteomic characterization of the released/secreted proteins of Leishmania (Viannia) braziliensis promastigotes
    Patricia Cuervo
    Laboratorio de Pesquisa em Leishmaniose, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil
    J Proteomics 73:79-92. 2009
    ..This study reports a suitable approach to identify secreted proteins in the culture supernatant of L. braziliensis and provides new perspectives for the study of molecules potentially involved in the early stages of infection...
  8. pmc Proteomic profile of culture filtrate from the Brazilian vaccine strain Mycobacterium bovis BCG Moreau compared to M. bovis BCG Pasteur
    Marcia Berrêdo-Pinho
    Laboratório de Genômica Funcional e Bioinformática, Instituto Oswaldo Cruz, FIOCRUZ, Avenida Brasil, 4365, Manguinhos, CEP 21040 900 Rio de Janeiro, RJ, Brazil
    BMC Microbiol 11:80. 2011
    ..CFPs are considered of great importance given their dominant immunogenicity and role in pathogenesis, being available for interaction with host cells since early infection...