Carlos A Mandarim-de-Lacerda

Summary

Affiliation: Rio de Janeiro
Country: Brazil

Publications

  1. pmc A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet
    Julio C Fraulob
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87 fds CEP 20551 030, Rio de Janeiro, Brazil
    J Clin Biochem Nutr 46:212-23. 2010
  2. pmc Maternal obesity during the preconception and early life periods alters pancreatic development in early and adult life in male mouse offspring
    Isabele Bringhenti
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e55711. 2013
  3. pmc Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice
    D Angelo Carlo Magliano
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e64258. 2013
  4. pmc Renin-angiotensin system blockers protect pancreatic islets against diet-induced obesity and insulin resistance in mice
    Eliete Dalla Corte Frantz
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e67192. 2013
  5. pmc Hepatic adverse effects of fructose consumption independent of overweight/obesity
    Alini Schultz
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de setembro 87 fds, Rio de Janeiro 20551 030, Brazil
    Int J Mol Sci 14:21873-86. 2013
  6. ncbi Volume-weighted mean nuclear volume and numerical nuclear density in the cardiomyocyte following enalapril and verapamil treatment
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Centro Biomedico, Instituto de Biologia, State University of Rio de Janeiro, Brazil
    Virchows Arch 438:92-5. 2001
  7. ncbi Glomerular developmental chronology in human fetuses
    J R Almeida
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    J Cell Mol Med 7:492-3. 2003
  8. ncbi Effect of antihypertensive drugs on the myocardial microvessels in rats with nitric oxide blockade
    L M Meirelles Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Institute of Biology, State University of Rio de Janeiro, Brazil
    Pathol Res Pract 196:305-11. 2000
  9. ncbi Effect of telmisartan on preexistent cardiac and renal lesions in spontaneously hypertensive mature rats
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Brazil
    Histol Histopathol 19:727-33. 2004
  10. ncbi Aorta wall quantitative alterations due to different long-term high-fat diet in rats
    Marcia Barbosa Aguila
    Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551 030 Rio de Janeiro, Brazil
    Food Chem Toxicol 41:1391-7. 2003

Collaborators

  • Marcia Barbosa Aguila
  • Wille Oigman
  • Alfredo de Souza Bomfim
  • J R Machado-Silva
  • Vanessa Souza-Mello
  • Fernanda A M Nascimento
  • Sandra Barbosa-da-Silva
  • Alini Schultz
  • Daniele G Bezerra
  • Isabele Bringhenti
  • L M Pereira
  • Jorge Reis Almeida
  • Leila M M Pereira
  • Fernanda Ornellas
  • Leila Maria Meirelles Pereira
  • Renata Heisler Neves
  • Jorge J Carvalho
  • Bianca M Gregorio
  • Caroline Fernandes-Santos
  • Carla C S Lemos
  • Thereza C Lonzetti Bargut
  • Liliane Soares C Oliveira
  • D Angelo Carlo Magliano
  • Diana F Serapiao-Moraes
  • Eliete Dalla Corte Frantz
  • Tatiane S Faria
  • Thais C Ceciliano
  • Antonio Ludgero-Correia
  • Geraldo O Silva-Junior
  • Rachel Bregman
  • Julio C Fraulob
  • Veronica C Villar-Martini
  • D A B Kasal
  • Daniele Gonçalves Bezerra
  • Bianca Martins Gregório
  • Felipe Nobre Moura
  • Alessandra R Pinheiro
  • Thiago da Silva Torres
  • Emmanuel Bazan
  • Alessandra Rocha Pinheiro
  • Leonardo de Souza Mendonca
  • Sergio da Cunha
  • Renata H Neves
  • Adriana K Burla
  • Alba Cristina Miranda de Barros Alencar
  • Delir Corrêa Gomes
  • Jorge Jose de Carvalho
  • Claudia M M Marques
  • Karla Maria Pereira Pires
  • Fernanda J Medeiros
  • Mariana Catta-Preta
  • Ana Maria Ribeiro Dos Santos
  • Virginia A V Costa
  • N Aparecida de Arantes Montagna
  • Pedro Paulo Horta
  • Fernanda Jurema Medeiros
  • Veronica C V Martini
  • Jorge R Almeida
  • Alfredo de Souza Bomfim
  • Wellington V Santos
  • Noemi Barbuto
  • G S Lopes
  • Anibal Sanchez Moura
  • A Pissinatti
  • J R Almeida
  • Eliete D C Frantz
  • R L de Andrade Zorzi
  • Silvana Regina de Melo
  • Daiane A Santos
  • Debora Neil
  • Michelle Rabello Cunha
  • Camila Crespo-Mascarenhas
  • Simone Nunes de Carvalho
  • Thereza Cristina Lonzetti Bargut
  • Jessica Andrade Moraes-Teixeira
  • Andre Rodrigues C Barreto-Vianna
  • Vanessa Souza Mello
  • Natalia C da Silva
  • Jessica R Lopes
  • Leonardo S Mendonca
  • Julio C Fraulob-Aquino
  • Marco A Bomfim
  • Tamiris Rachid
  • Fernando S Cardoso-de-Lemos
  • L M Meirelles Pereira
  • Lais de Carvalho
  • Rebeca Ogg-Diamantino
  • Mario F Neves
  • Margareth Maria Gomes de Souza
  • M F Neves

Detail Information

Publications89

  1. pmc A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet
    Julio C Fraulob
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87 fds CEP 20551 030, Rio de Janeiro, Brazil
    J Clin Biochem Nutr 46:212-23. 2010
    ..Additionally, the importance of fat accumulation in the pancreas has been recently highlighted. Therefore, this model could help to elucidate target organ alterations associated with metabolic syndrome...
  2. pmc Maternal obesity during the preconception and early life periods alters pancreatic development in early and adult life in male mouse offspring
    Isabele Bringhenti
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e55711. 2013
    ..In conclusion, a maternal HF diet consumed during the preconceptional period and throughout the gestational and lactational periods in mice results in dramatic alterations in the pancreata of the offspring...
  3. pmc Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice
    D Angelo Carlo Magliano
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e64258. 2013
    ....
  4. pmc Renin-angiotensin system blockers protect pancreatic islets against diet-induced obesity and insulin resistance in mice
    Eliete Dalla Corte Frantz
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 8:e67192. 2013
    ..The effect of RAS inhibition on type 2 diabetes is still unclear; however, RAS seems to play an important role in the regulation of the pancreas and glucose intolerance of mice fed high-fat (HF) diet...
  5. pmc Hepatic adverse effects of fructose consumption independent of overweight/obesity
    Alini Schultz
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de setembro 87 fds, Rio de Janeiro 20551 030, Brazil
    Int J Mol Sci 14:21873-86. 2013
    ..These conditions are associated with a poor prognosis. ..
  6. ncbi Volume-weighted mean nuclear volume and numerical nuclear density in the cardiomyocyte following enalapril and verapamil treatment
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Centro Biomedico, Instituto de Biologia, State University of Rio de Janeiro, Brazil
    Virchows Arch 438:92-5. 2001
    ..With respect to cardiomyocyte nuclear size, the present results suggest a beneficial effect of the angiotensin-converting enzyme inhibitor enalapril and the calcium channel blocker verapamil when NO synthesis is blockaded...
  7. ncbi Glomerular developmental chronology in human fetuses
    J R Almeida
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    J Cell Mol Med 7:492-3. 2003
  8. ncbi Effect of antihypertensive drugs on the myocardial microvessels in rats with nitric oxide blockade
    L M Meirelles Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Institute of Biology, State University of Rio de Janeiro, Brazil
    Pathol Res Pract 196:305-11. 2000
    ..These results are compatible with the occurrence of angiogenesis in the verapamil rats...
  9. ncbi Effect of telmisartan on preexistent cardiac and renal lesions in spontaneously hypertensive mature rats
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Brazil
    Histol Histopathol 19:727-33. 2004
    ..Telmisartan is able to attenuate SHR cardiomyocyte and glomerular hypertrophies, and myocardial reactive fibrosis as well. It also is favorable to the intramyocardial microcirculation...
  10. ncbi Aorta wall quantitative alterations due to different long-term high-fat diet in rats
    Marcia Barbosa Aguila
    Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551 030 Rio de Janeiro, Brazil
    Food Chem Toxicol 41:1391-7. 2003
    ..These results suggest that the dietary intake of canola oil could attenuate the aorta structure aging process with a favorable BP maintenance...
  11. ncbi Numerical density of cardiomyocytes in chronic nitric oxide synthesis inhibition
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Pathobiology 68:36-42. 2000
    ..The purpose of this study was to estimate the numerical density of cardiomyocytes that is able to show cardiomyocyte loss as a consequence of NOS inhibition...
  12. ncbi Heart and blood pressure adaptations in Wistar rats fed with different high-fat diets for 18 months
    Marcia B Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Nutrition 19:347-52. 2003
    ..We investigated the effect of long-term administration of four different high-fat diets on systolic blood pressure (SBP), body and heart biometry, and left ventricular myocyte nuclei number (N[lvm])...
  13. ncbi Aortic wall remodeling in rats with nitric oxide deficiency treated by enalapril or verapamil
    Leila M M Pereira
    Laboratório de Morfometria and Morfologia Cardiovascular, Universidade do Estado do Rio de Janeiro, Centro Biomedico, Av 28 de Setembro, 87 fds CEP 20551 030, Rio de Janeiro, RJ, Brazil
    Pathol Res Pract 200:211-7. 2004
    ....
  14. ncbi The effects of spironolactone monotherapy on blood pressure and myocardial remodeling in spontaneously hypertensive rats: a stereological study
    Carlos Alberto Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    J Biomed Sci 10:50-7. 2003
    ..Long-term spironolactone monotherapy showed a partial effect in the preservation of intramyocardial vessels and also in the attenuation of interstitial fibrosis...
  15. ncbi Effect of different high-fat diets on the myocardium stereology and blood pressure in rats
    M B Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro UERJ, Brazil
    Pathol Res Pract 196:841-6. 2000
    ..Comparing three high-fat diets, the data suggest that the diet canola oil had a major beneficial effect, preserving the myocardial structure and the blood pressure in rats...
  16. ncbi Myocardial microcirculation stereological changes in rats subjected to nitric oxide synthesis inhibition
    L M Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro, Brazil
    Pathol Res Pract 195:177-81. 1999
    ..Although these changes may be caused by NO inhibition and not by arterial hypertension, further comparative studies on different models of arterial hypertension are needed to confirm this hypothesis...
  17. ncbi Heart biometry and allometry in rats submitted to nitric oxide synthesis blockade and treatment with antihypertensive drugs
    C A Mandarim-de-Lacerda
    Institute of Biology, State University of Rio de Janeiro, Brazil
    Ann Anat 183:171-6. 2001
    ..Cardiac hypertrophy in rats under inhibition of NO synthesis was prevented by treatment with enalapril and verapamil more efficiently than spironolactone...
  18. ncbi Renal cortical remodelling by NO-synthesis blockers in rats is prevented by angiotensin-converting enzyme inhibitor and calcium channel blocker
    C A Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro UERJ, Brazil
    J Cell Mol Med 5:276-83. 2001
    ..The renal cortical region showed glomerular sclerosis/hypertrophy and tubular remodelling in rats with NOs blockade that was efficiently prevented with the simultaneous treatment with enalapril or verapamil...
  19. ncbi Stereological tools in biomedical research
    Carlos A Mandarim-de-Lacerda
    Laboratorio de Morfometria e Morfologia Cardiovascular, Departamento de Anatomia, Instituto de Biologia, Universidade do Estado do Rio de Janeiro, 20551 030 Rio de Janeiro, Brasil
    An Acad Bras Cienc 75:469-86. 2003
    ..In the present text, a short review of the main stereological tools is done as a background basis to non-expert scientists...
  20. ncbi Cardiomyocyte volume-weighted nuclear volume and spironolactone therapy in spontaneously hypertensive rats
    Carlos Alberto Mandarim-de-Lacerda
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87 fds, 20551 030, Rio de Janeiro, RJ, Brazil
    Anal Quant Cytol Histol 24:331-6. 2002
    ....
  21. ncbi Myocardial stereological adaptations in wistar rats fed with different high-fat diets during 18 months
    M B Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro UERJ, Brasil
    J Nutr Sci Vitaminol (Tokyo) 47:387-93. 2001
    ..These results support the notion that the long-term use of canola oil in the diet is better to preserve the myocardium structure, including microvascularization, than soybean oil or lard and egg yolk...
  22. ncbi Stereology of cardiac hypertrophy induced by NO blockade in rats treated with enalapril and verapamil
    L M Pereira
    Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Anal Quant Cytol Histol 23:330-8. 2001
    ..To quantify the structural myocardial response when chronic NO blockade hypertension is treated with antihypertensive drugs...
  23. ncbi Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet
    Vanessa Souza-Mello
    Laboratory of Morphometry, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551 030 Rio de Janeiro, RJ, Brazil
    Clin Sci (Lond) 119:239-50. 2010
    ..The best results were achieved using telmisartan and sitagliptin as monotherapies or as a dual treatment, combining partial PPAR-gamma agonism and PPAR-alpha activation in the liver with extended incretin action...
  24. ncbi Effects of rosiglitazone (a peroxysome proliferator-activated receptor gamma agonist) on the blood pressure and aortic structure in metabolically programmed (perinatal low protein) rats
    Thiago da Silva Torres
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Hypertens Res 31:965-75. 2008
    ..00001 for TS, two-way ANOVA). We conclude that rosiglitazone has beneficial effects in reducing the BP and the aortic tunica media hypertrophy with consequent balance of the wall stress in metabolically programmed offspring...
  25. doi Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring
    Bianca M Gregorio
    Institute of Biology, Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro, Biomedical Center, Rio de Janeiro, Brazil
    Am J Obstet Gynecol 203:495.e1-8. 2010
    ..This work aimed to verify the hypothesis that maternal intake of high-fat diet in critical periods of pregnancy and/or suckling period predisposes nonalcoholic fatty liver disease in adult C57BL/6 mice offspring...
  26. ncbi Sexual dimorphism in fat distribution and metabolic profile in mice offspring from diet-induced obese mothers
    Fernanda Ornellas
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Life Sci 93:454-63. 2013
    ..To investigate whether the effects of diet-induced obesity in mothers are passed on to their offspring fed a control diet in a gender-specific manner...
  27. doi Adipose tissue, liver and pancreas structural alterations in C57BL/6 mice fed high-fat-high-sucrose diet supplemented with fish oil (n-3 fatty acid rich oil)
    Fernanda A M Nascimento
    Laboratorio de Morfometria e Morfologia Cardiovascular, Centro Biomedico, Instituto de Biologia, Universidade do Estado do Rio de Janeiro, Av 28 de Setembro 87 fds 20551 030 Rio de Janeiro, RJ, Brasil
    Exp Toxicol Pathol 62:17-25. 2010
    ..Furthermore, fish oil improves glucagon and GLUT-2 expressions when it is decreased in insulin, but in hepatocyte binucleation and hepatic steatosis where the effect is reduced...
  28. ncbi Enalapril attenuates cardiorenal damage in nitric-oxide-deficient spontaneously hypertensive rats
    Leila M M Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 20551 030 Rio de Janeiro, Brazil
    Clin Sci (Lond) 106:337-43. 2004
    ..Enalapril administration also decreases cardiac and renal structural damage caused by genetic hypertension, as well as by the interaction between genetic hypertension and NO deficiency...
  29. doi Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease
    Alini Schultz
    Laboratory of Morphometry, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, RJ, Brazil
    Exp Toxicol Pathol 64:273-82. 2012
    ..These data reinforce the notion that swimming exercise can be considered an efficient nonpharmacologic therapy in the treatment of NAFLD, obesity and insulin resistance...
  30. ncbi Hepatic structural alteration in adult programmed offspring (severe maternal protein restriction) is aggravated by post-weaning high-fat diet
    Vanessa Souza-Mello
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de setembro 87 fds, 20551 030 Rio de Janeiro, RJ, Brazil
    Br J Nutr 98:1159-69. 2007
    ..All of these serve to highlight the paramount importance of intra-uterine conditions and postnatal diet quality when it comes to the pathogenesis of chronic diseases...
  31. pmc The effect of enalapril on the cardiac remodelling in ovariectomized spontaneously hypertensive rats
    Wellington V Santos
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Int J Exp Pathol 85:287-94. 2004
    ..In conclusion, ovariectomy, in SHRs, causes cardiac hypertrophy and an unfavourable myocardial remodelling. Of the spectrum of changes seen, the major effect of enalapril appears to be mediated via an increase in the density of ive...
  32. doi Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL/6 mice
    Antonio Ludgero-Correia
    Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Nutrition 28:316-23. 2012
    ..To test this hypothesis, ovariectomized (OVX) mice were fed a HF diet, and we investigated the lipid metabolism, adipose tissue remodeling, adipokines, and inflammatory cytokines...
  33. ncbi Exercise training attenuates cardiovascular adverse remodeling in adult ovariectomized spontaneously hypertensive rats
    Claudia M M Marques
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Menopause 13:87-95. 2006
    ..To study the combined effects of ovariectomy and regular exercise training on hypertension and on cardiac and aortic remodeling in spontaneously hypertensive rats (SHR)...
  34. ncbi Renal cortex remodeling in streptozotocin-induced diabetic spontaneously hypertensive rats treated with olive oil, palm oil and fish oil from Menhaden
    Fernanda J Medeiros
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro UERJ, Rio de Janeiro RJ 20551 030, Brazil
    Prostaglandins Leukot Essent Fatty Acids 75:357-65. 2006
    ..The olive oil, palm oil and mainly fish oil intake retard the usual loss of glomeruli and attenuate the renal cortex adverse remodeling of Db and non-Db SHR...
  35. doi Maternal fish oil supplementation benefits programmed offspring from rat dams fed low-protein diet
    Bianca Martins Gregório
    Department of Anatomy, Biomedical Center, Institute of Biology, Laboratory of Morphometry and Cardiovascular Morphology Rio de Janeiro, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Am J Obstet Gynecol 199:82.e1-7. 2008
    ..We hypothesized that maternal fish oil supplementation would prevent the programming of offspring cardiovascular alterations...
  36. doi An early fish oil-enriched diet reverses biochemical, liver and adipose tissue alterations in male offspring from maternal protein restriction in mice
    Isabele Bringhenti
    Laboratory of Morphometry, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, RJ, Brazil
    J Nutr Biochem 22:1009-14. 2011
    ..Early fish oil intake has beneficial effects on the programming responses that control body fat pad, glucose and lipid metabolism, and liver and adipose tissue structure in adult programmed offspring...
  37. ncbi Maternal caffeine administration leads to adverse effects on adult mice offspring
    Diana F Serapiao-Moraes
    Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87, fundos, FCM, terreo, Rio de Janeiro, 20551 030, Brazil
    Eur J Nutr 52:1891-900. 2013
    ..This study aimed to evaluate the role of caffeine chronic administration during gestation of C57BL/6 mice on cardiac remodeling and the expression of components of the renin-angiotensin system (RAS) in male offspring as adults...
  38. ncbi Protein restriction during gestation and/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats
    Alessandra R Pinheiro
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, 20551 030 Rio de Janeiro, Brazil
    Clin Sci (Lond) 114:381-92. 2008
    ..These findings suggest that low protein during gestation and/or lactation can be passed transgenerationally to the second generation...
  39. ncbi Spontaneously hypertensive rats left ventricular cardiomyocyte loss attenuation through different edible oils long-term intake
    Marcia B Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Int J Cardiol 100:461-6. 2005
    ..There are no information available whether different edible lipids long-term administration does potentiality alter the usual cardiomyocyte loss in SHR or not...
  40. ncbi Eplerenone offsets cardiac and aortic adverse remodeling in spontaneously hypertensive rats
    Adriana K Burla
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, State University of Rio de Janeiro, Av 28 de Setembro 87 fds 20551 030 Rio de Janeiro, Rio de Janeiro, Brazil
    Int J Cardiol 114:64-70. 2007
    ..Several studies have shown beneficial effects of eplerenone in hypertension and left ventricular dysfunction, but its action on cardiac and vascular changes secondary to blood pressure elevation are not clear yet...
  41. ncbi Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats
    Daniele G Bezerra
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Brazil
    Clin Sci (Lond) 108:349-55. 2005
    ....
  42. pmc Maternal vitamin D deficiency delays glomerular maturity in F1 and F2 offspring
    Fernanda A M Nascimento
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    PLoS ONE 7:e41740. 2012
    ..There is a high prevalence of vitamin D insufficiency in women of reproductive age...
  43. ncbi Hypertension and kidney alterations in rat offspring from low protein pregnancies
    Veronica C Villar-Martini
    Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    J Hypertens Suppl 27:S47-51. 2009
    ..Therefore, this study was undertaken to investigate early and late glomerular structural alterations in both sexes of Wistar rat offspring from dams submitted to severe low protein intake during gestation...
  44. ncbi Offspring myocardium alteration from dams submitted to nitric oxide synthesis inhibition during pregnancy
    Veronica C V Martini
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Int J Cardiol 100:377-82. 2005
    ..Nitric oxide synthesis (NOS) inhibition during pregnancy alters offspring cardiac structure...
  45. doi Insights into coronary artery development in model of maternal protein restriction in mice
    Geraldo O Silva-Junior
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Anat Rec (Hoboken) 294:1757-64. 2011
    ..Maternal protein restriction in mice leads to a delay in the growth of the heart in the embryonic period modifying the development of the subepicardial peritruncal plexus and the apoptosis in the future coronary orifice region...
  46. ncbi Maternal gestational protein-calorie restriction decreases the number of glomeruli and causes glomerular hypertrophy in adult hypertensive rats
    Jorge R Almeida
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    Am J Obstet Gynecol 192:945-51. 2005
    ..This work analyzed the renal function and structure in offspring rats that were submitted to maternal protein-calorie restriction during prenatal or lactation periods...
  47. pmc Weight cycling enhances adipose tissue inflammatory responses in male mice
    Sandra Barbosa-da-Silva
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    PLoS ONE 7:e39837. 2012
    ..Nutritional interventions such as dieting are often accompanied by repeated bouts of weight loss and regain, a phenomenon known as weight cycling (WC)...
  48. ncbi Alpha-tocopherol supplementation favorable effects on blood pressure, blood viscosity and cardiac remodeling of spontaneously hypertensive rats
    Virginia A V Costa
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro UERJ, Brazil
    J Nutr Biochem 16:251-6. 2005
    ..This was observed by a reduction of both blood viscosity and BP, and a consequent cardiomyocyte hypertrophy in treated SHRs; an improvement of vessels-to-myocytes ratio in these rats was also observed...
  49. ncbi Transgenerational effects on the liver and pancreas resulting from maternal vitamin D restriction in mice
    Fernanda A M Nascimento
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro
    J Nutr Sci Vitaminol (Tokyo) 59:367-74. 2013
    ....
  50. ncbi Light and confocal microscopic observations of adult Schistosoma mansoni from mice fed on a high-fat diet
    Renata H Neves
    Laboratory of Helminthology Romero Lascasas Porto, Department of Microbiology, Immunology and Parasitology, Faculty of Medical Sciences, Biomedical Center, Rua Prof Manuel de Abreu 444 50 andar, Vila Isabel, Rio de Janeiro, Brazil
    J Helminthol 81:361-8. 2007
    ..The data presented here are the first to report the role of a cholesterol-rich diet affecting the development of S. mansoni worms...
  51. ncbi Myocardial changes after spironolactone in spontaneous hypertensive rats. A laser scanning confocal microscopy study
    Leila Maria Meirelles Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Brazil
    J Cell Mol Med 6:49-57. 2002
    ..This action on the myocardium is more efficient when the spironolactone (even in medium dose) was associated with enalapril or verapamil...
  52. ncbi Amlodipine preserves the glomerular number in spontaneously hypertensive rats
    Daniele G Bezerra
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brasil
    J Cell Mol Med 9:966-71. 2005
    ..05). A possible protective effect of amlodipine against the loss of glomeruli in SHR is a major additional action of amlodipine in the treatment of hypertension mainly when the renal lesion already exists...
  53. doi The inflammatory profile and liver damage of a sucrose-rich diet in mice
    Liliane Soares C Oliveira
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    J Nutr Biochem 25:193-200. 2014
    ..It is still unclear if an isoenergetic, sucrose-rich diet leads to health consequences...
  54. ncbi Liver damage is not reversed during the lean period in diet-induced weight cycling in mice
    Sandra Barbosa-da-Silva
    Laboratory of Morphometry, Metabolism and Cardiovascular Disease, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Hepatol Res . 2013
    ....
  55. pmc The effect of enalapril and verapamil on the left ventricular hypertrophy and the left ventricular cardiomyocyte numerical density in rats submitted to nitric oxide inhibition
    L M Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Brazil
    Int J Exp Pathol 82:115-22. 2001
    ..In conclusion, the left ventricular hypertrophy and the significant decrease of the left ventricular cardiomyocyte number caused by the NO synthesis inhibition are efficiently prevented with the use of enalapril and verapamil...
  56. ncbi Effect of unilateral nephrectomy on renal function of diabetic rats
    G S Lopes
    Nephrology Division, Pedro Ernesto Hospital, University of the State of Rio de Janeiro, Rio de Janeiro, Brazil
    Histol Histopathol 19:1085-8. 2004
    ..The present data suggest that the acceleration of glomerular lesions in DMNx animals was more closely associated to hemodynamic adaptations than to glomerular hypertrophy...
  57. ncbi Beneficial effect of enalapril in spontaneously hypertensive rats cardiac remodeling with nitric oxide synthesis blockade
    R L de Andrade Zorzi
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brasil
    J Cell Mol Med 6:599-608. 2002
    ....
  58. ncbi Gender-related differences in kidney of rats with chronic renal failure
    Carla C S Lemos
    Nephrology Division, Biomedical Center, State University of Rio de Janeiro, Brazil
    Histol Histopathol 29:479-87. 2014
    ..In summary, proteinuria was higher in males and appeared early in the course of CRF, probably contributing to fibrotic events. Data were influenced by gender suggesting that male sex hormones aggravate renal alterations. ..
  59. ncbi Effects of a diet rich in n-3 polyunsaturated fatty acids on hepatic lipogenesis and beta-oxidation in mice
    Thereza C Lonzetti Bargut
    Laboratório de Morfometria, Metabolismo e Doença Cardiovascular, Centro Biomedico Instituto de Biologia, Universidade do Estado do Rio de Janeiro, Av 28 de setembro 87 fds, Rio de Janeiro, RJ, Brazil
    Lipids 49:431-44. 2014
    ..In conclusion, a diet rich in fish oil has beneficial effects on hepatic insulin resistance, lipogenesis and beta-oxidation and prevents hepatic tissue from liver damage and NAFLD. ..
  60. ncbi Allopurinol attenuates L-NAME induced cardiomyopathy comparable to blockade of angiotensin receptor
    D A B Kasal
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, Rio de Janeiro, Brazil
    Histol Histopathol 23:1241-8. 2008
    ..The protective action of this drug is comparable to the results obtained with olmesartan. Antioxidative mechanisms are proposed to account for the pressure independent effects of allopurinol...
  61. ncbi Different edible oil beneficial effects (canola oil, fish oil, palm oil, olive oil, and soybean oil) on spontaneously hypertensive rat glomerular enlargement and glomeruli number
    M B Aguila
    Laboratorio de Morfometria e Morfologia Cardiovascular, Centro Biomedico, Instituto de Biologia, Universidade do Estado do Rio de Janeiro, Brazil
    Prostaglandins Other Lipid Mediat 76:74-85. 2005
    ....
  62. ncbi Glomerular profile numerical density per area and mean glomerular volume in rats submitted to nitric oxide synthase blockade
    L M Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Brazil
    Histol Histopathol 16:15-20. 2001
    ..0001) and, concomitantly, L-NAME rats had the v (glom) 33% higher than the control ones (p=0.004). These results demonstrate morphological renal alterations caused by NOS inhibition and hypertension...
  63. ncbi Stereology of the myocardium in Leontopithecus (Lesson, 1840) callitrichidae - primates
    A Pissinatti
    Centro de Primatologia do Rio de Janeiro CPRJ FEEMA, Rio de Janeiro, Brazil
    J Med Primatol 32:139-47. 2003
    ..These characteristics may explain the faster development of L. rosalia infants as compared with that of L. chrysomelas and L. c. chrysopygus kept under the same handling conditions at the CPRJ-FEEMA...
  64. ncbi Leprosy: contribution of mast cells to epineurial collagenization
    N Aparecida de Arantes Montagna
    Department of Pathology, School of Medicine, State University of Rio de Janeiro, Brazil
    Clin Neuropathol 24:284-90. 2005
    ..Tryptase, the most abundant protein product of human mast cells, has been shown to be mitogenic for fibroblasts and to increase type I collagen production...
  65. ncbi Effects of long-term intake of edible oils on hypertension and myocardial and aortic remodelling in spontaneously hypertensive rats
    Marcia Barbosa Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro, Biomedical Center, Institute of Biology, Av 28 de setembro 87 fds, 20551 030 Rio de Janeiro, RJ, Brazil
    J Hypertens 22:921-9. 2004
    ..The nature of dietary lipid intake contributes to blood pressure control...
  66. ncbi Renal cortex remodeling in nitric oxide deficient rats treated with enalapril
    Noemi Barbuto
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    J Cell Mol Med 8:102-8. 2004
    ....
  67. ncbi Long-term intake of edible oils benefits blood pressure and myocardial structure in spontaneously hypertensive rat (SHR) and streptozotocin diabetic SHR
    Fernanda Jurema Medeiros
    Universidade do Estado do Rio de Janeiro, Centro Biomedico, Instituto de Biologia, Laboratório de Morfometria e Morfologia Cardiovascular Av 28 de Setembro, 87 fds Rio de Janeiro, RJ 20551 030, Brazil
    Prostaglandins Other Lipid Mediat 78:231-48. 2005
    ..Long-term edible oil supplementation showed beneficial effects decreasing BP levels and offsetting adverse myocardial remodeling in diabetic SHR...
  68. ncbi Gender determines long-lasting effects on adult offspring heart after early-life malnourishment
    Anibal Sanchez Moura
    Laboratory of Physiology of Nutrition and Development, Department of Physiological Sciences, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Biol Neonate 85:256-62. 2004
    ..Also this association was observed in the animals at 60 days of age when the insulin/glucose ratio of the MM animals was 45% greater than that observed in the FM group...
  69. ncbi Dietary effect of different high-fat diet on rat liver stereology
    Marcia Barbosa Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro UERJ, RJ, Brazil
    Liver Int 23:363-70. 2003
    ..Dietary habits are considered to be responsible for a fatty liver. The aims of this work are to study the effects of different lipid sources on rat hepatic structure...
  70. ncbi Kidney adaptation in nitric oxide-deficient Wistar and spontaneously hypertensive rats
    Leila Maria Meirelles Pereira
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87 fds 20551 030, Rio de Janeiro, RJ, Brazil
    Life Sci 74:1375-86. 2004
    ..Administration of enalapril, but not L-NAME, changed this tendency. However, enalapril was not totally effective in preventing vascular damage in SHR NO deficient animals...
  71. ncbi Effects of chronic high fat diets on renal function and cortical structure in rats
    Marcia Barbosa Aguila
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro UERJ, Brazil
    Exp Toxicol Pathol 55:187-95. 2003
    ..The addition of canola oil in the LE mixture normally was not efficient to alter the renal damage except in the cortical vessels...
  72. ncbi Enalapril alters the formation of the collagen matrix in spontaneously hypertensive rats
    Alfredo de Souza Bomfim
    Instituto de Biologia Roberto Alcantara Gomes, UERJ, Rio de Janeiro, RJ, Brazil
    Arq Bras Cardiol 81:69-72, 64-8. 2003
    ..To assess the effect of the inhibition of the angiotensin-converting enzyme on the collagen matrix (CM) of the heart of newborn spontaneously hypertensive rats (SHR) during embryonic development...
  73. ncbi Lipid metabolism in rats fed diets containing different types of lipids
    Marcia Barbosa Aguila
    Centro Biomedico, Instituto de Biologia, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, 20551 030, Brazil
    Arq Bras Cardiol 78:25-38. 2002
    ..To assess the effect of different types of lipid diets on the lipid metabolism of aging rats...
  74. ncbi Effects of ACE inhibition during fetal development on cardiac microvasculature in adult spontaneously hypertensive rats
    Alfredo de Souza Bomfim
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Int J Cardiol 101:237-42. 2005
    ..Early angiotensin-converting enzyme (ACE) inhibition is able to re-program spontaneously hypertensive rats (SHR) to express an attenuated form of disease in adulthood...
  75. ncbi Overweight is gender-dependent in prenatal protein--calorie restricted adult rats acting on the blood pressure and the adverse cardiac remodeling
    Jorge Reis Almeida
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Brazil
    Life Sci 77:1307-18. 2005
    ..In conclusion: hypertension and body and cardiac growth were influenced by the interaction between gender and prenatal nutritional conditions, while cardiac remodeling seems to be only programmed by the adverse intrauterine environment...
  76. pmc Cardiac and aortic structural alterations due to surgically-induced menopause associated with renovascular hypertension in rats
    Leonardo de Souza Mendonca
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, Brazil
    Int J Exp Pathol 88:301-9. 2007
    ..However, renovascular hypertension exerts a far greater influence than surgically-induced menopause in this parameter...
  77. ncbi Hepatic stereology of Schistosomiasis mansoni infected-mice fed a high-fat diet
    Renata Heisler Neves
    Laboratorio de Helmintos Parasitos de Vertebrados, Departamento de Helmintologia, Instituto Oswaldo Cruz FIOCRUZ, Av Brasil 4365, 21040 900 Rio de Janeiro, RJ, Brazil
    Mem Inst Oswaldo Cruz 101:253-60. 2006
    ..0004), and Vv[hf] (p = 0.0007). In conclusion, schistosomiasis mansoni infection with concurrent high-fat diet promotes intensive quantitative changes in hepatic structure, contributing to an increasing on hepatic regeneration...
  78. ncbi Cardiac alterations in furosemide-treated thiamine-deprived rats
    Sergio da Cunha
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, State University of Rio de Janeiro, Brazil
    J Card Fail 13:774-84. 2007
    ..Chronic administration of furosemide may induce thiamine deficiency and cause or aggravate myocardial dysfunction...
  79. ncbi Long-term feeding a high-fat diet causes histological and parasitological effects on murine schistosomiasis mansoni outcome
    Renata Heisler Neves
    Laboratory of Helminthology Romero Lascasas Porto, Biomedical Center, Department of Pathology and Laboratories, Faculty of Medical Sciences, State University of Rio de Janeiro, Brazil
    Exp Parasitol 115:324-32. 2007
    ..The morphometric evaluation of hepatic granulomas did not reach statistical significance (p>0.05) between diets assayed. The high-fat diet for long-term produces effects on schistosomiasis mansoni outcome...
  80. doi Atorvastatin attenuates cardiomyocyte loss in adult rats from protein-restricted dams
    Daniele Gonçalves Bezerra
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Centre, Institute of Biology, State University of Rio de Janeiro, Av 28 de Setembro, 87 fds 20551 030 Rio de Janeiro, RJ, Brasil
    J Card Fail 14:151-60. 2008
    ..Statins are cholesterol-lowering drugs that have been proved to prevent cardiac events. Their direct effects on cardiac remodeling, when administered in programmed protein restricted animals, still are unknown...
  81. ncbi Adult cardiorenal benefits from postnatal fish oil supplement in rat offspring of low-protein pregnancies
    Mariana Catta-Preta
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Life Sci 80:219-29. 2006
    ..In conclusion, FO supplement, which is a rich source of n-3 fatty acids (DHA and EPA), has beneficial effects on BP control and cardiac and renal adverse remodeling usually seen in offspring of the LP pregnancies...
  82. ncbi Beneficial effects of physical exercise on hypertension and cardiovascular adverse remodeling of diet-induced obese rats
    Alessandra Rocha Pinheiro
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil
    Nutr Metab Cardiovasc Dis 17:365-75. 2007
    ..Obesity is present among all age groups and in all socioeconomic groups. This study on obese rats aims to quantify the beneficial effects of physical exercise on blood pressure (BP), the heart, the elasticity and resistance of arteries...
  83. ncbi Early renal structure alteration in rat offspring from dams fed low protein diet
    Karla Maria Pereira Pires
    Biomedical Center, Institute of Biology, Laboratory of Morphometry and Cardiovascular Morphology, State University of Rio de Janeiro, Brazil
    Life Sci 79:2128-34. 2006
    ..This supports epidemiological data in humans underlying why fetuses with low birth weight carry an increased risk of mortality from chronic diseases in adulthood, including hypertension...
  84. ncbi Exercise training attenuates blood pressure elevation and adverse remodeling in the aorta of spontaneously hypertensive rats
    Pedro Paulo Horta
    Laboratory of Morphometry and Cardiovascular Morphology, Biomedical Center, Institute of Biology, State University of Rio de Janeiro, Brazil
    Life Sci 77:3336-43. 2005
    ..To observe the extracellular matrix modifications and quantify the structural alterations of the aortic wall in spontaneously hypertensive rats (SHR) submitted to an aerobic physical activity (PA) protocol...
  85. ncbi Nasal bone length in human fetuses by X-ray
    Felipe Nobre Moura
    Department of Orthodontics of Dentistry School, Federal University of Rio de Janeiro, Brazil
    Early Hum Dev 84:459-64. 2008
    ..To construct a normal range for the prenatal nasal bone length (NBL) in Brazilians irrespective to the knowledge of the ethnic genetic background...
  86. ncbi Stereologic study of the sinoatrial node of rats -- age related changes
    Silvana Regina de Melo
    Department of Morphophysiological Sciences, State University of Maringa, Av Colombo, 5790, 87020 900, Maringa, Parana, Brazil
    Biogerontology 3:383-90. 2002
    ..In conclusion, the aging process implies changes in the cell and fiber content of the sinoatrial node...
  87. ncbi Quantitative study of the comma-shaped body, S-shaped body and vascularized glomerulus in the second and third human gestational trimesters
    Jorge Reis Almeida
    Biomedical Center, Laboratory of Morphometry and Cardiovascular Morphology, Institute of Biology, State University of Rio de Janeiro, Brazil
    Early Hum Dev 69:1-13. 2002
    ..The rat developing metanephros has been quantified, but not the human developing kidney...
  88. ncbi Low molecular weight heparin in the treatment of puromycin-induced nephrosis
    Ana Maria Ribeiro Dos Santos
    Nephrology Division, University of State of Rio de Janeiro, Rio de Janeiro, Brazil
    Pathol Res Pract 202:157-63. 2006
    ..In conclusion, LMWH interferes in the complications of PAN model, but not through inhibition of the proteinuria...
  89. ncbi Ultrastructural and biochemical changes of the medial pterygoid muscle induced by unilateral exodontia
    Emmanuel Bazan
    Faculty of Medicine, Federal University of Sao Paulo UNIFESP, Sao Paulo, SP, Brazil
    Micron 39:536-43. 2008
    ....