Abouch Valenty Krymchantowski

Summary

Affiliation: Rio de Janeiro
Country: Brazil

Publications

  1. ncbi Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug
    A V Krymchantowski
    Headache Center of Rio and Institute of Neurology Deolindo Couto UFRJ, Rio de Janeiro, Brasil
    Arq Neuropsiquiatr 59:708-11. 2001
  2. ncbi Rizatriptan in migraine
    Abouch Valenty Krymchantowski
    Instituto de Neurologia Deolindo Couto, Av das Americas 1155 1608 Barra Rio de Janeiro, Brazil
    Expert Rev Neurother 5:597-603. 2005
  3. ncbi Polytherapy in the preventive and acute treatment of migraine: fundamentals for changing the approach
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, 22031 070, Brazil
    Expert Rev Neurother 6:283-9. 2006
  4. ncbi Rizatriptan vs. rizatriptan plus trimebutine for the acute treatment of migraine: a double-blind, randomized, cross-over, placebo-controlled study
    A V Krymchantowski
    Instituto de Neurologia Deolindo Couto, Rio de Janeiro, Brazil
    Cephalalgia 26:871-4. 2006
  5. ncbi The future of acute care and prevention in headache
    A V Krymchantowski
    Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, Brazil
    Neurol Sci 28:S166-78. 2007
  6. ncbi Adherence to headache treatment and profile of previous health professional seeking among patients with chronic headache: a retrospective analysis
    Abouch Valenty Krymchantowski
    Outpatient Headache Unit, Instituto de Neurologia Deolindo Couto, Department of Neurology, Hospital Pasteur, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil
    MedGenMed 9:21. 2007
  7. ncbi The experience of combining agents, specially triptans and non steroidal anti-inflammatory drugs, for the acute treatment of migraine - a review
    Abouch V Krymchantowski
    Headache Center of Rio Rio de Janeiro, Brazil
    Recent Pat CNS Drug Discov 2:141-4. 2007
  8. ncbi Lysine clonixinate versus dipyrone (metamizole) for the acute treatment of severe migraine attacks: a single-blind, randomized study
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Rio de Janeiro, RJ, Brazil
    Arq Neuropsiquiatr 66:216-20. 2008
  9. ncbi Migraine prevention trials and optimized acute therapy: translating lessons learned into clinical practice
    Abouch Valenty Krymchantowski
    Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, Brazil
    Curr Pain Headache Rep 12:220-3. 2008
  10. ncbi Quetiapine for the prevention of migraine refractory to the combination of atenolol + nortriptyline + flunarizine: an open pilot study
    Abouch V Krymchantowski
    Headache Center of Rio, Rio de Janeiro, RJ, Brazil
    Arq Neuropsiquiatr 66:615-8. 2008

Detail Information

Publications27

  1. ncbi Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug
    A V Krymchantowski
    Headache Center of Rio and Institute of Neurology Deolindo Couto UFRJ, Rio de Janeiro, Brasil
    Arq Neuropsiquiatr 59:708-11. 2001
    ..The aim of this study was to evaluate whether patients presenting frequent recurrence with the combination triptan plus NSAID, would decrease it with the association of dexamethasone...
  2. ncbi Rizatriptan in migraine
    Abouch Valenty Krymchantowski
    Instituto de Neurologia Deolindo Couto, Av das Americas 1155 1608 Barra Rio de Janeiro, Brazil
    Expert Rev Neurother 5:597-603. 2005
    ..Rizatriptan is a selective agonist of the 5-hydroxytryptophan(1B/1D )receptors, with proven superiority over placebo, ergotamine and selected oral triptans, demonstrating a good profile of safety and tolerability...
  3. ncbi Polytherapy in the preventive and acute treatment of migraine: fundamentals for changing the approach
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, 22031 070, Brazil
    Expert Rev Neurother 6:283-9. 2006
    ..Although highly speculative, these hypotheses could stimulate further controlled studies to support changing the current paradigm of monotherapeutic migraine treatment in some patients...
  4. ncbi Rizatriptan vs. rizatriptan plus trimebutine for the acute treatment of migraine: a double-blind, randomized, cross-over, placebo-controlled study
    A V Krymchantowski
    Instituto de Neurologia Deolindo Couto, Rio de Janeiro, Brazil
    Cephalalgia 26:871-4. 2006
    ..Recurrence was similar among the two drug regimens, as well as adverse events. The combination rizatriptan and trimebutine is more effective than rizatriptan alone. The combination does not increase adverse events or recurrence of pain...
  5. ncbi The future of acute care and prevention in headache
    A V Krymchantowski
    Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, Brazil
    Neurol Sci 28:S166-78. 2007
    ..The same is true of cluster headache, which affects only about 0.07%-0.4% of most populations. This review focuses on current and emerging agents and procedures for the treatment of migraine and cluster headache...
  6. ncbi Adherence to headache treatment and profile of previous health professional seeking among patients with chronic headache: a retrospective analysis
    Abouch Valenty Krymchantowski
    Outpatient Headache Unit, Instituto de Neurologia Deolindo Couto, Department of Neurology, Hospital Pasteur, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil
    MedGenMed 9:21. 2007
    ..This retrospective study evaluated the relationship between treatment and the profiles of previous health professionals consulted by patients in a tertiary headache center...
  7. ncbi The experience of combining agents, specially triptans and non steroidal anti-inflammatory drugs, for the acute treatment of migraine - a review
    Abouch V Krymchantowski
    Headache Center of Rio Rio de Janeiro, Brazil
    Recent Pat CNS Drug Discov 2:141-4. 2007
    ..This article focuses on the review of available literature for treating migraine attacks with two or more agents, related patents as well as analyzes the characteristics of the recently approved fixed combination sumatriptan-naproxen...
  8. ncbi Lysine clonixinate versus dipyrone (metamizole) for the acute treatment of severe migraine attacks: a single-blind, randomized study
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Rio de Janeiro, RJ, Brazil
    Arq Neuropsiquiatr 66:216-20. 2008
    ..The aim of this study was to evaluate the efficacy and tolerability of the intravenous formulations of LC and dipyrone in the treatment of severe migraine attacks...
  9. ncbi Migraine prevention trials and optimized acute therapy: translating lessons learned into clinical practice
    Abouch Valenty Krymchantowski
    Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, Brazil
    Curr Pain Headache Rep 12:220-3. 2008
    ..We hope that these achievements will create a stable path of management to benefit our patients, without interruption, into the foreseeable future...
  10. ncbi Quetiapine for the prevention of migraine refractory to the combination of atenolol + nortriptyline + flunarizine: an open pilot study
    Abouch V Krymchantowski
    Headache Center of Rio, Rio de Janeiro, RJ, Brazil
    Arq Neuropsiquiatr 66:615-8. 2008
    ..Migraine is a prevalent neurological disorder. Although prevention is the mainstream treatment, some patients are refractory to standard therapies...
  11. ncbi Aura with non-migraine headache
    Abouch Valenty Krymchantowski
    Outpatient Headache Unit, Instituto de Neurologia Deolindo Couto, Headache Center of Rio, Rua Siqueira, Campos 43 1002, Copacabana Rio de Janeiro, 22031 070 Brazil
    Curr Pain Headache Rep 9:264-7. 2005
    ..The possibility of a specific genetic origin for the auras, not related to the primary headache type, also is raised...
  12. ncbi Primary headache diagnosis among chronic daily headache patients
    Abouch Valenty Krymchantowski
    Department of Neurology, Universidade Federal Fluminense, Rio de Janeiro, RJ Brasil
    Arq Neuropsiquiatr 61:364-7. 2003
    ....
  13. ncbi Overuse of symptomatic medications among chronic (transformed) migraine patients: profile of drug consumption
    Abouch Valenty Krymchantowski
    Centro de Avalia o e Tratamento da Dor de Cabe a do Rio de Janeiro, Departamento de Neurologia, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil
    Arq Neuropsiquiatr 61:43-7. 2003
    ....
  14. ncbi Rizatriptan combined with rofecoxib vs. rizatriptan for the acute treatment of migraine: an open label pilot study
    A V Krymchantowski
    Rio Military Police, Department of Neurology, Universidade Federal Fluminense, Headache Center of Rio, Rio de Janeiro, Brazil
    Cephalalgia 22:309-12. 2002
    ..Double-blind, placebo-controlled studies are necessary to confirm these observations...
  15. ncbi Out-patient detoxification in chronic migraine: comparison of strategies
    A V Krymchantowski
    Department of Neurology, Universidade Federal Fluminense, Niteroi, Rio de Janeiro, Brazil
    Cephalalgia 23:982-93. 2003
    ..Further controlled studies are necessary to confirm these observations...
  16. ncbi Acute treatment of migraine. Breaking the paradigm of monotherapy
    Abouch Valenty Krymchantowski
    Department of Neurology, Universidade Federal Fluminense, Rio de Janeiro, Brazil
    BMC Neurol 4:4. 2004
    ....
  17. ncbi [Topiramate in the preventive treatment of migraine: experience in a tertiary center]
    Abouch Valenty Krymchantowski
    Departamento de Neurologia, Universidade Federal Fluminense, Niteroi, RJ, Brazil
    Arq Neuropsiquiatr 62:91-5. 2004
    ..In addition, the side effect profile was acceptable. Further controlled studies are necessary to confirm these observations...
  18. ncbi Rizatriptan versus rizatriptan plus rofecoxib versus rizatriptan plus tolfenamic acid in the acute treatment of migraine
    Abouch Valenty Krymchantowski
    Department of Neurology, Universidade Federal Fluminense, Niteroi, Brazil
    BMC Neurol 4:10. 2004
    ..rizatriptan plus a COX-2 enzyme inhibitor (rofecoxib, RO) vs. rizatriptan plus a traditional NSAID (tolfenamic acid, TO). We were also interested in comparing the efficacy rates within these three groups...
  19. ncbi Rofecoxib in migraine
    Abouch Valenty Krymchantowski
    Expert Rev Neurother 5:55-61. 2005
    ..In addition, the limitations of a monotherapeutic orally administered approach and possible ways of raising the efficacy of rofecoxib and other acute migraine treatments are reviewed...
  20. ncbi New and emerging prophylactic agents for migraine
    Abouch V Krymchantowski
    Department of Neurology, Universidade Federal Fluminense and Institute of Neurology Deolindo Couto, Rio de Janeiro, Brazil
    CNS Drugs 16:611-34. 2002
    ..There is an expectation that modern neuroscience will soon provide more efficacious and better tolerated prophylactic medications for migraine...
  21. ncbi Topiramate plus nortriptyline in the preventive treatment of migraine: a controlled study for nonresponders
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Rua Siqueira Campos 43 1002 Copacabana, Rio de Janeiro, 22031 070, Brazil
    J Headache Pain 13:53-9. 2012
    ..04). Finally we conclude that combination therapy (of TPM and NTP) is effective in patients with incomplete benefit using these agents in monotherapy...
  22. ncbi Lysine clonixinate vs naproxen sodium for the acute treatment of migraine: a double-blind, randomized, crossover study
    Abouch Valenty Krymchantowski
    Outpatient Headache Unit, Instituto de Neurologia Deolindo Couto, Department of Neurology, Hospital Pasteur, Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil
    MedGenMed 7:69. 2005
    ..COMMENTS: Although this study did not include a placebo arm, which impairs any definitive efficacy claims, we found LC and NS to be similarly effective and well tolerated in patients presenting moderate or severe attacks of migraine...
  23. ncbi Low-dose topiramate plus sodium divalproate for positive responders intolerant to full-dose monotherapy
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Headache, Rio de Janeiro, Brazil
    Headache 52:129-32. 2012
    ..Neuromodulators such as topiramate (TPM) and divalproex sodium (DVS) are effective in the preventive treatment of migraine. Nonetheless, patients often discontinue their use due to side effects...
  24. ncbi Headaches due to external compression
    Abouch Valenty Krymchantowski
    Headache Center of Rio, Copacabana, Rio de Janeiro, Brazil
    Curr Pain Headache Rep 14:321-4. 2010
    ..The mechanism responsible is the compression of trigeminal or occipital nerves branches. The headache resolves after pressure is relieved, or is prevented by avoiding the precipitating cause. Drugs are rarely used...
  25. ncbi Amitriptyline versus amitriptyline combined with fluoxetine in the preventative treatment of transformed migraine: a double-blind study
    Abouch Valenty Krymchantowski
    Headache Center of Rio and Instituto de Neurologia Deolindo Couto/UFRJ, Rio de Janeiro, Brazil
    Headache 42:510-4. 2002
    ..Because of the small number of subjects involved and the short duration of our study, a type II error cannot be excluded...
  26. ncbi Chronic (transformed) migraine and medication overuse: to withdraw or not?
    Abouch Valenty Krymchantowski
    Expert Rev Neurother 7:1065-7. 2007
  27. ncbi Combining therapies for the treatment of migraine: is there a role?
    Abouch Valenty Krymchantowski
    Expert Rev Neurother 5:145-7. 2005