Akira Homma

Summary

Affiliation: Rio de Janeiro
Country: Brazil

Publications

  1. pmc Subdoses of 17DD yellow fever vaccine elicit equivalent virological/immunological kinetics timeline
    Ana Carolina Campi-Azevedo
    Centro de Pesquisas Rene Rachou Fiocruz, Belo Horizonte, Minas Gerais, Brazil
    BMC Infect Dis 14:391. 2014
  2. doi request reprint Vaccine research, development, and innovation in Brazil: a translational science perspective
    Akira Homma
    Bio Manguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil
    Vaccine 31:B54-60. 2013
  3. doi request reprint The Brazilian vaccine manufacturers' perspective and its current status
    Akira Homma
    Bio Manguinhos Fiocruz, Pavilhão Rocha Lima, Manguinhos, Rio de Janeiro, Brasil
    Biologicals 37:173-6. 2009
  4. ncbi request reprint [Vaccines, immunization and technological innovation: an update]
    Akira Homma
    Instituto de Tecnologia em Imunobiológicos de Bio Manguinhos, Rio de Janeiro RJ
    Cien Saude Colet 16:445-58. 2011
  5. ncbi request reprint Immunogenicity, reactogenicity and consistency of production of a Brazilian combined vaccine against diphtheria, tetanus, pertussis and Haemophilus influenzae type b
    Reinaldo de Menezes Martins
    Assessoria Clínica, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 103:711-8. 2008
  6. ncbi request reprint Study of the genetic stability of measles virus CAM-70 vaccine strain after serial passages in chicken embryo fibroblasts primary cultures
    Maria Beatriz Borges
    Bio Manguinhos, Fundacao Oswaldo Cruz, Av Brasil, 4365 Manguinhos, Rio de Janeiro, RJ 21040 360, Brazil
    Virus Genes 36:35-44. 2008
  7. doi request reprint Immunogenicity and safety of measles-mumps-rubella vaccine delivered by disposable-syringe jet injector in healthy Brazilian infants: A randomized non-inferiority study
    Reinaldo de Menezes Martins
    Bio Manguinhos Fiocruz, Manguinhos, Rio de Janeiro, Brazil Electronic address
    Contemp Clin Trials 41:1-8. 2015
  8. pmc Historical review of clinical vaccine studies at Oswaldo Cruz Institute and Oswaldo Cruz Foundation--technological development issues
    Reinaldo de Menezes Martins
    Bio Manguinhos Fiocruz, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 110:114-24. 2015
  9. ncbi request reprint Incidence of hypotonic-hyporesponsive episodes associated to the combined DTP/Hib vaccine used in Brazilian National Immunizations Program
    Reinaldo M Martins
    Fundação Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brazil
    J Pediatr (Rio J) 83:523-8. 2007
  10. pmc 17DD yellow fever vaccine: a double blind, randomized clinical trial of immunogenicity and safety on a dose-response study
    Reinaldo M Martins
    Bio Manguinhos, Fiocruz Rio de Janeiro, Brazil
    Hum Vaccin Immunother 9:879-88. 2013

Collaborators

  • Luiz Antonio Bastos Camacho
  • Darin Zehrung
  • Reinaldo Menezes Martins
  • Reinaldo de Menezes Martins
  • Marcos da Silva Freire
  • Maria de Lourdes Sousa Maia
  • Anna Maya Yoshida Yamamura
  • Ana Carolina Campi-Azevedo
  • Ricardo Galler
  • Maria Beatriz Borges
  • Maria Cristina F Lemos
  • Marilda Mendonça Siqueira
  • Michael Royals
  • Elizabeth Maciel de Albuquerque
  • Vanessa Dos Reis von Doellinger
  • Courtney Jarrahian
  • Birute Curran
  • Maria das Graças Tavares Ribeiro
  • Laura Saganic
  • Gabriela Villela-Rezende
  • Edson Pereira Filho
  • Paula de Almeida Estevam
  • Darcy Akemi Hokama
  • Roberto Henrique Guedes Farias
  • Luiz Fernando Carvalho Almeida
  • Sheila Maria Barbosa Lima
  • Olindo Assis Martins-Filho
  • Patrícia Flávia Quaresma
  • Gloria Regina Silva Sá
  • Andréa Teixeira-Carvalho
  • Ricardo Aguiar Villanova Freire
  • Jordana Grazziela Coelho-Dos-Reis
  • Vanessa Peruhype-Magalhães
  • Rita Maria Ribeiro Nogueira
  • Ricardo de Carvalho
  • Maria da Luz Fernandes Leal
  • Alfredo V Jabor
  • José Marcus N Malachias
  • Marcos S Freire
  • Elena Caride

Detail Information

Publications10

  1. pmc Subdoses of 17DD yellow fever vaccine elicit equivalent virological/immunological kinetics timeline
    Ana Carolina Campi-Azevedo
    Centro de Pesquisas Rene Rachou Fiocruz, Belo Horizonte, Minas Gerais, Brazil
    BMC Infect Dis 14:391. 2014
    ..The present work aimed at comparing the serum chemokine and cytokine kinetics triggered by five subdoses of 17DD YF Vaccine...
  2. doi request reprint Vaccine research, development, and innovation in Brazil: a translational science perspective
    Akira Homma
    Bio Manguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil
    Vaccine 31:B54-60. 2013
    ..We also discuss the lessons learned from the Brazilian experience in the implementation of governmental policies on vaccine innovation that could be applicable to other developing countries...
  3. doi request reprint The Brazilian vaccine manufacturers' perspective and its current status
    Akira Homma
    Bio Manguinhos Fiocruz, Pavilhão Rocha Lima, Manguinhos, Rio de Janeiro, Brasil
    Biologicals 37:173-6. 2009
    ....
  4. ncbi request reprint [Vaccines, immunization and technological innovation: an update]
    Akira Homma
    Instituto de Tecnologia em Imunobiológicos de Bio Manguinhos, Rio de Janeiro RJ
    Cien Saude Colet 16:445-58. 2011
    ..Brazil has also established a new innovation policy, creating new laws as well as subsidizing projects in technological innovation and modernization of production infra-structure...
  5. ncbi request reprint Immunogenicity, reactogenicity and consistency of production of a Brazilian combined vaccine against diphtheria, tetanus, pertussis and Haemophilus influenzae type b
    Reinaldo de Menezes Martins
    Assessoria Clínica, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 103:711-8. 2008
    ..Adverse events rates were comparable among the vaccine groups. The Brazilian DTP/Hib vaccine demonstrated an immunogenicity and reactogenicity profile similar to that of the reference vaccine...
  6. ncbi request reprint Study of the genetic stability of measles virus CAM-70 vaccine strain after serial passages in chicken embryo fibroblasts primary cultures
    Maria Beatriz Borges
    Bio Manguinhos, Fundacao Oswaldo Cruz, Av Brasil, 4365 Manguinhos, Rio de Janeiro, RJ 21040 360, Brazil
    Virus Genes 36:35-44. 2008
    ..This study shows that the measles CAM-70 vaccine virus is highly adapted to its cultivation conditions and that its genetic stability contributes, in part, to the safety profile of the vaccine...
  7. doi request reprint Immunogenicity and safety of measles-mumps-rubella vaccine delivered by disposable-syringe jet injector in healthy Brazilian infants: A randomized non-inferiority study
    Reinaldo de Menezes Martins
    Bio Manguinhos Fiocruz, Manguinhos, Rio de Janeiro, Brazil Electronic address
    Contemp Clin Trials 41:1-8. 2015
    ..Recommendations for future DSJI clinical studies include rigorous training of vaccinators, quantitative measurement of wetness on the skin following injection, and regular monitoring of device and vaccinator performance. ..
  8. pmc Historical review of clinical vaccine studies at Oswaldo Cruz Institute and Oswaldo Cruz Foundation--technological development issues
    Reinaldo de Menezes Martins
    Bio Manguinhos Fiocruz, Rio de Janeiro, RJ, Brasil
    Mem Inst Oswaldo Cruz 110:114-24. 2015
    ..We recommend national policy strategies to overcome existing regulatory and financing constraints. ..
  9. ncbi request reprint Incidence of hypotonic-hyporesponsive episodes associated to the combined DTP/Hib vaccine used in Brazilian National Immunizations Program
    Reinaldo M Martins
    Fundação Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brazil
    J Pediatr (Rio J) 83:523-8. 2007
    ..To evaluate the safety of a combined diphtheria-tetanus-whole cell pertussis-Haemophilus influenzae type b vaccine used on the Brazilian National Immunizations Program, chiefly the incidence of hypotonic-hyporesponsive episodes...
  10. pmc 17DD yellow fever vaccine: a double blind, randomized clinical trial of immunogenicity and safety on a dose-response study
    Reinaldo M Martins
    Bio Manguinhos, Fiocruz Rio de Janeiro, Brazil
    Hum Vaccin Immunother 9:879-88. 2013
    ..To verify if the Bio-Manguinhos 17DD yellow fever vaccine (17DD-YFV) used in lower doses is as immunogenic and safe as the current formulation...