Research Topics
| José Rodrigues CouraSummaryAffiliation: Rio de Janeiro Country: Brazil Publications
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Publications
Chagas disease. What is known and what should be improved: a systemic reviewJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
Rev Soc Bras Med Trop 45:286-96. 2012..Finally, we raise the need for to create a new initiative for controlling Chagas disease in the Gran Chaco, which involves parts of Argentina, Bolivia and Paraguay...- Risks of endemicity, morbidity and perspectives regarding the control of Chagas disease in the Amazon RegionJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 107:145-54. 2012.... - A critical review on Chagas disease chemotherapyJosé Rodriques Coura
Departamento de Medicina Tropical, Instituto Oswaldo Cruz FIOCRUZ, Av Brasil 4365, 21045 900 Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 97:3-24. 2002.... - A new challenge for malaria control in Brazil: asymptomatic Plasmodium infection--a reviewJosé Rodrigues Coura
Departamento de Medicina Tropical, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, 21040 900, Brasil
Mem Inst Oswaldo Cruz 101:229-37. 2006..If a mean of 25% is taken for the asymptomatic infection caused by Plasmodium sp. in the Amazon region of Brazil, malaria control will be difficult to achieve in that region with the measures currently utilized for such control... - Epidemiological and control aspects of schistosomiasis in Brazilian endemic areasJ R Coura
Departamento de Medicina Tropical, Instituto Oswaldo Cruz FIOCRUZ, Av Brasil 4365, 21045 900 Rio de Janeiro, RJ, Brazil
Mem Inst Oswaldo Cruz 99:13-9. 2004.... - [Transmission of chagasic infection by oral route in the natural history of Chagas disease]José Rodrigues Coura
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 39:113-7. 2006.... - Chagas disease: what is known and what is needed--a background articleJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, 21045 900, Brasil
Mem Inst Oswaldo Cruz 102:113-22. 2007..Several acute cases have been reported from Amazon region most of them by T. cruzi I, Z3, and a hybrid ZI/Z3. We conclude this article presenting the ten top Chagas disease needs for the near future... - Present situation and new strategies for Chagas disease chemotherapy: a proposalJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro 21040 360, Brasil
Mem Inst Oswaldo Cruz 104:549-54. 2009.... - Epidemiology, control and surveillance of Chagas disease: 100 years after its discoveryJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 104:31-40. 2009..These measures should be complemented by surveillance and primary, secondary and tertiary care... 
Chagas disease: 100 years after its discovery. A systemic reviewJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, Brazil
Acta Trop 115:5-13. 2010..The epidemiological and control characteristics of Chagas disease vary according to each country's ecological conditions and health policies...- Chagas disease in the Brazilian Amazon: IV. a new cross-sectional studyJosé Rodrigues Coura
Instituto Oswaldo Cruz, FIOCRUZ, Brasil
Rev Inst Med Trop Sao Paulo 44:159-65. 2002..8% of them had a positive serology for T. cruzi infection. Electrocardiographic alterations were shown in 9.3% of the seropositives and in 11.9% of the seronegative cases. This was considered not statistically significant... - Emerging Chagas disease in Amazonian BrazilJosé Rodrigues Coura
Dept of Tropical Medicine, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil
Trends Parasitol 18:171-6. 2002..cruziZ3/Z1 ASAT--are present. It appears that T. cruzil has an extant capacity for genetic exchange. Attention is also drawn to the risk of domestic endemicity, in addition to the tasks facing the disease control authorities... - Specific schistosomiasis treatment as a strategy for disease controlJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz FIOCRUZ, FIOCRUZ, Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 105:598-603. 2010..We conclude that specific treatment of schistosomiasis reduces the prevalence of infection in the short-term and the morbidity due to schistosomiasis in medium to long-term time frames, but does not help to control disease transmission... - Chronic phase of Chagas disease: why should it be treated? A comprehensive reviewJosé Rodrigues Coura
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brasil
Mem Inst Oswaldo Cruz 106:641-5. 2011.... - [Morbidity of Chagas disease among autochthonous patients from the Rio Negro microregion, State of Amazonas]Lucia Maria Brum-Soares
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 43:170-7. 2010..A seroepidemiological and clinical study was conducted on 152 autochthonous individuals living in the district of Barcelos, State of Amazonas, to evaluate the seroprevalence of Chagas infection and morbidity of Chagas disease... - Cross-sectional study defines difference in malaria morbidity in two Yanomami communities on Amazonian boundary between Brazil and VenezuelaTeodardo José Marcano
Departamento de Medicina Tropical, Instituto Oswaldo Cruz FIOCRUZ, Av Brasil 4365, 21045 900 Rio de Janeiro, RJ, Brazil
Mem Inst Oswaldo Cruz 99:369-76. 2004.... - Age-dependent acquisition of protective immunity to malaria in riverine populations of the Amazon Basin of BrazilSimone Ladeia-Andrade
Department of Tropical Medicine, Oswaldo Cruz Institute, Rio de Janeiro, Brazil
Am J Trop Med Hyg 80:452-9. 2009..These findings suggest that the continuous exposure to hypo- or mesoendemic malaria may induce significant anti-parasite and anti-disease immunity in native Amazonians... - [Prevalence of left ventricular aneurysms among chronic Chagas disease patients from two areas in the State of Piauí, Brazil]José Borges-Pereira
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Avenida Brasil 4365, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 40:521-6. 2007..These results show that there was low prevalence of left ventricle aneurysms among patients from João Costa and high concentration of thrombi among patients from São João do Piauí... - Mass treatment for intestinal helminthiasis control in an Amazonian endemic area in BrazilMarcio Neves Boia
Laboratório de Doenças Parasitárias, Departamento de Medicina Tropical, IOC, FiocruzRJ, Brasil
Rev Inst Med Trop Sao Paulo 48:189-95. 2006..However, governmental plans for public health, education and urban infrastructure are essential for the sustained reduction of prevalences of those infections... - [Chronic chagasic cardiopathy in the Rio Negro, Amazon State. Report of three new autochthonous cases confirmed by serology, clinical examination, chest X-rays, electro and echocardiography]Sergio Salles Xavier
Instituto de Pesquisa Clinica Evandro Chagas, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 39:211-6. 2006..These are the first autochthonous cases of chronic Chagasic cardiomyopathy from the Brazilian Amazon state with echocardiographic pattern suggestive of Chagas' disease... - [Evaluation of the thick smear in a field condition in a malaria endemic area in the Middle Region of Rio Negro, Amazon]Martha Cecília Suárez-Mútis
Departamento de Medicina Tropical do Instituto Oswaldo Cruz da Fundação Oswaldo Cruz, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 39:495-7. 2006..05). In areas of asymptomatic infection, improvement in the sensibility of thick smears by increasing the number of microscopic fields read or using other more accurate diagnostic malaria techniques alone or in combination is fundamental... - Should Trypanosoma cruzi be called "cruzi" complex? a review of the parasite diversity and the potential of selecting population after in vitro culturing and mice infectionRodolfo Devera
Departmento de Medicina Tropical, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, 21045 900, Brasil
Mem Inst Oswaldo Cruz 98:1-12. 2003..The interaction of the different infecting clones of the cruzi complex and the human host will determine the morbidity of the disease... - Cross sectional study reveals a high percentage of asymptomatic Plasmodium vivax infection in the Amazon Rio Negro area, BrazilMartha C Suarez-Mútis
Laboratório de Doenças Parasitárias, Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
Rev Inst Med Trop Sao Paulo 49:159-64. 2007..Only one 12 year old girl presented a positive thick blood smear for P. vivax. This is the first description of asymptomatic Plasmodium infection in this area studied... - [Seroprevalence of Chagas disease infection in the State of Piauí, 2002]José Borges-Pereira
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brazil
Rev Soc Bras Med Trop 39:530-9. 2006..0% to 1.9%), which was indicative of the efficacy of the vector control measures implemented between 1975 and 2002... - Naturally acquired antibodies to merozoite surface protein (MSP)-1(19) and cumulative exposure to Plasmodium falciparum and Plasmodium vivax in remote populations of the Amazon Basin of BrazilSimone Ladeia-Andrade
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz FIOCRUZ, 21045 900 Rio de Janeiro, Brasil
Mem Inst Oswaldo Cruz 102:943-51. 2007.... - [Changes in the epidemiological pattern of malaria in a rural area of the middle Rio Negro, Brazilian Amazon: a retrospective analysis]Martha Cecília Suárez Mútis
Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Av Brasil 4365, Rio de Janeiro, RJ 21045 900, Brazil
Cad Saude Publica 23:795-804. 2007..vivax from 24% to 35% (all these differences were statistically significant, with p < 0.05). The changes in the epidemiological pattern of malaria in the Padauiri area will be further elucidated through prospective studies... - [Emmanuel Dias: the principal architect of the fight against Chagas disease in the Americas]João Carlos Pinto Dias
Centro de Pesquisa Rene Rachou, Fundacao Oswaldo Cruz, Belo Horizonte, MG
Rev Soc Bras Med Trop 41:502-4. 2008..Dias was recently said to be the scientist who had had the all-time greatest impact on this trypanosomiasis... - A thirty years follow-up study on Schistosomiasis mansoni in a community of Minas Gerais, BrazilMaria José Conceição
Programa de Pós Graduação em Doenças Infecciosas e Parasitárias, Departamento de Medicina Preventiva, Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, 21941 590 Rio de Janeiro, Brasil
Mem Inst Oswaldo Cruz 102:1007-9. 2007..2% in 1984, 27.3% in 1994, and 19.4% in 2003, while the index of hepatosplenomegaly were respectively 5.8%, 2.8%, 2.3% and 1.3%. The maintenance of high prevalence and severity of clinical forms are probably related to reinfection... - Fungal flora of the digestive tract of 5 species of triatomines vectors of Trypanosoma cruzi, Chagas 1909A M Moraes
Departamento de Micologia, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro RJ, Brazil
Mycopathologia 151:41-8. 2001..Among the isolated fungi, we found species that are recognized as entomopathogenic and pathogenic for humans and animals... - Chagas disease: from bush to huts and houses. Is it the case of the Brazilian Amazon?J R Coura
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil
Mem Inst Oswaldo Cruz 94:379-84. 1999..cruzi antibodies. A strong correlation of seroreactivity with the contact of gatherers of piaçava fibers with wild triatomines could be evidenced... - [Dilated cardiomyopathy in patients with chronic chagasic infection: report of two fatal autochthonous cases from Rio Negro, State of Amazonas, Brazil]Pedro Viñas Albajar
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, R J, Brasil
Rev Soc Bras Med Trop 36:401-7. 2003..An in situ PCR was positive for Trypanosoma cruzi... - Effect of a participatory educational program on primary school teachers' knowledge of malariaMartha Cecília Suárez-Mútis
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
Rev Saude Publica 45:931-7. 2011..To describe a participatory educational program for building up knowledge on malaria among primary school teachers in a highly endemic city... - Human study and experimental behavior of Schistosoma mansoni isolates from patients with different clinical forms of schistosomiasisMaria José Conceição
Department of Preventive Medicine, Infectious and Parasitic Diseases Post Graduation, Clementino Fraga Filho Hospital, Universidade Federal do Rio de Janeiro, UFRJ, Rio de Janeiro, Brazil
Acta Trop 108:98-103. 2008.... - Morphobiological aspects of Rhodnius brethesi Matta, 1919 (Hemiptera:Reduviidae) from the Upper and Middle Negro River, Amazon region of Brazil: I - scanning electron microscopyJacenir Reis Dos Santos-Mallet
Departamento de Entomologia, Instituto Oswaldo Cruz, FiocruzRio de Janeiro, RJ, Brazil
Mem Inst Oswaldo Cruz 100:915-23. 2005.... - Tuberculosis and intestinal parasitism among indigenous people in the Brazilian Amazon regionMarcio Neves Boia
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
Rev Saude Publica 43:176-8. 2009..35.4% for Entamoeba histolyticaD dispar and 33.3% vs. 10.7% for Giardia lamblia). It is concluded that tuberculosis and intestinal parasitism are frequent in these communities, thus requiring control measures and better medical care... - Night and crepuscular mosquitoes and risk of vector-borne diseases in areas of piassaba extraction in the middle Negro River basin, state of Amazonas, BrazilMartha Cecília Suárez-Mútis
Laboratório de Doenças Parasitárias, Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brasil, 21045 900
Mem Inst Oswaldo Cruz 104:11-7. 2009..The diversity of insects found reveals the receptivity of the area towards a variety of diseases facilitated by the presence of vectors involved in the transmission of Plasmodium, arboviruses and other infectious agents... - [Biodemes of Trypanosoma cruzi strains isolated from humans from three endemic areas in Minas Gerais State]Rodolfo Devera
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ
Rev Soc Bras Med Trop 35:323-30. 2002..It was not possible to establish a relationship between the biodeme strain and the severity of the disease in the patients... 
Evaluation of three commercial enzyme-linked immunosorbent assays for diagnosis of Chagas' diseaseW M Oelemann
Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
J Clin Microbiol 36:2423-7. 1998..Depending on the area under investigation, the three commercial kits produced specificity values between 93.3 and 100.0%, sensitivity values between 97.7 and 100%, and accuracies ranging from 93.6 to 100.0%...- Two main clusters within Trypanosoma cruzi zymodeme 3 are defined by distinct regions of the ribosomal RNA cistronM B A Mendonça
Departamento de Medicina Tropical and Departamento de Imunologia, Instituto Oswaldo Cruz, Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil
Parasitology 124:177-84. 2002..This study shows that the rDNA cistron allows the definition of 2 distinct subclusters in Z3 isolates... - In vivo and in vitro metacyclogenesis tests of two strains of Trypanosoma cruzi in the triatomine vectors Triatoma pseudomaculata and Rhodnius neglectus: short/long-term and comparative studyC J Carvalho-Moreira
Department of Tropical Medicine, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil 4365, Rio de Janeiro, CEP 21045 RJ, Brazil
Exp Parasitol 103:102-11. 2003..neglectus than in T. pseudomaculata... - Spotted fever in Brazil: a seroepidemiological study and description of clinical cases in an endemic area in the state of São PauloE R de Lemos
Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Rio de Janeiro, Brazil
Am J Trop Med Hyg 65:329-34. 2001..Twenty-two (4.2%) of these samples demonstrated titers > or = 1:64. The results indicate that Brazilian spotted fever is endemic within this region of Brazil... - The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar culturesAlessandra Queiroga Gonçalves
Laboratório de Doenças Parasitárias, Departamento de Medicina Tropical, Fundacao Oswaldo Cruz, Rio de Janeiro, RJ, Brasil
Rev Inst Med Trop Sao Paulo 49:201-2. 2007..hominis from cultures of E. histolytica/E. dispar, thereby maintaining the integrity of the trophozoites of the amebas. Nystatin presented low efficacy (33.3%)... - The genetic diversity of Brazilian Trypanosoma cruzi isolates and the phylogenetic positioning of zymodeme 3, based on the internal transcribed spacer of the ribosomal geneS S Santos
Department of Tropical Medicine, Instituto Oswaldo Cruz, , Avenida Brazil 4365, Manguinhos, Rio de Janeiro, RJ, CEP: 21045-900, Brazil
Ann Trop Med Parasitol 96:755-64. 2002..The results of the subsequent phylogenetic analysis confirmed the presence of the two major groups of T. cruzi and showed that zymodeme 3, a third iso-enzymatic sub-group, is closer to T. cruzi I than to T. cruzi II... - Morphologic, karyotypic, and molecular evidence of a new form of Chiropotes (primates, pitheciinae)C R Bonvicino
Genetics Division, Diretoria de Pesquisa, Instituto Nacional de Cancer, Rio de Janeiro, Brazil
Am J Primatol 61:123-33. 2003..israelita. This species, C. s. chiropotes, and C. s. utahicki are allopatric. Pelage coloration, karyotype, and molecular analysis strongly indicate that C. chiropotes, C. utahicki, and Chiropotes israelita deserve species status...