Research Topics
| F G C AbathSummaryAffiliation: Rio de Janeiro Country: Brazil Publications
| Collaborators
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Detail Information
Publications
Molecular approaches for the detection of Schistosoma mansoni: possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infectionFrederico G C Abath
Departamentos de Imunologia, Centro de Pesquisas Aggeu Magalhaes FIOCRUZ, Av Prof Moraes Rego s n, 50670 420 Recife, PE, Brazil
Mem Inst Oswaldo Cruz 101:145-8. 2006..The present minireview describes sensitive and specific PCR based systems to detect S. mansoni, indicating possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infection...
Single-tube nested PCR using immobilized internal primersF G C Abath
Departamento de Imunologia, , , 50670-420, Recife, Brazil
Biotechniques 33:1210-2, 1214. 2002
Immunopathogenic mechanisms in schistosomiasis: what can be learnt from human studies?Frederico G C Abath
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, Fundacao Oswaldo Cruz, Avenida Professor Moraes Rego s n, Cidade Universitaria, 50670 420 Recife, Brazil
Trends Parasitol 22:85-91. 2006....
Development of molecular approaches for the identification of transmission sites of schistosomiasisFábio L Melo
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes FIOCRUZ, Av Prof Moraes Rego s n, Cidade Universitaria, 50670 420, Recife, Brazil
Trans R Soc Trop Med Hyg 100:1049-55. 2006..These PCR protocols have potential to be used as tools for monitoring of schistosome transmission...
Development of a real time polymerase chain reaction for quantitation of Schistosoma mansoni DNAAna Lisa do Vale Gomes
Departamento de Imunologia, , Av. Prof Moraes Rego s/n, 50670-420 Recife, PE, Brazil
Mem Inst Oswaldo Cruz 101:133-6. 2006..Thus, these PCR protocols have potential to be used as tools for monitoring of schistosome transmission and quantitative diagnosis of human infection...
Canine visceral leishmaniosis: a comparative analysis of the EIE-leishmaniose-visceral-canina-Bio-Manguinhos and the IFI-leishmaniose-visceral-canina-Bio-Manguinhos kitsR A Lira
Departamento de Imunologia, , , Av. Moraes Rego s/n, , 50670-420, Recife-PE, Brazil
Vet Parasitol 137:11-6. 2006....
Single-tube nested PCR using immobilized internal primers for the identification of dengue virus serotypesA L V Gomes
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes FIOCRUZ, Av Moraes Rego s n, Cidade Universitaria, 50670 420 Recife, Brazil
J Virol Methods 145:76-9. 2007....
Diagnosis of canine visceral leishmaniasis: biotechnological advancesY M Gomes
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, Fundação Oswaldo Cruz FIOCRUZ, Av Moraes Rego s n, Cidade Universitaria, 50670 420 Recife, PE, Brazil
Vet J 175:45-52. 2008..The development of polymerase chain reaction based approaches and immunoassays based on the use of recombinant antigens aimed at improving the sensitivity and specificity of CVL diagnosis is discussed...
Immunological diagnosis of tuberculosis based on recombinant antigens ESAT-6 and CFP-10 in children from an endemic area in northeast BrazilD S M Van-Lume
Aggeu Magalhães Research Center Oswaldo Cruz Institute FIOCRUZ, Department of Immunology, Av Moares Rego s n, Recife, Pernambuco, Brazil
Scand J Immunol 72:460-8. 2010..In conclusion, the ESAT-6 test may be the most appropriate for diagnosis of childhood TB, both LTBI and TB disease, when associated with epidemiological and clinical data, especially in endemic areas such as Brazil...
Preliminar evaluation of cytokines in the hepatitis C-schistosomiasis co-infectionClarice N L Morais
, Av. Prof. Moraes Rego, 52020-020 Recife, PE, Brazil
Mem Inst Oswaldo Cruz 101:353-4. 2006..Several studies have proposed serum biological markers of hepatic fibrosis. This communication evaluates the use of serum cytokines as markers of hepatic fibrosis in hepatitis C, schistosomiasis, and co-infection...
Development of a single tube hemi-nested PCR for genus-specific detection of Plasmodium in oligoparasitemic patientsLílian M L Montenegro
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, FIOCRUZ, Av Moraes Rego s n, Cidade Universitaria, 50670 420, Recife, Brazil
Trans R Soc Trop Med Hyg 98:619-25. 2004..We conclude that these sensitive molecular diagnostic systems can be used for the diagnosis of asymptomatic oligoparasitemic patients...
Preliminary results on interleukin-4 and interleukin-10 cytokine production in malnourished, inducible nitric oxide synthase-deficient mice with schistosomiasis mansoni infectionRenata P Ramos
, Departamento de Imunologia, , 52020-020 Recife, PE, Brazil
Mem Inst Oswaldo Cruz 101:331-2. 2006..We are currently investigating the biological significance of these findings...
The development of a real-time PCR assay for the quantification of Leishmania infantum DNA in canine bloodMilena de Paiva Cavalcanti
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes FIOCRUZ, Av Prof Moraes Rego s n, Cidade Universitaria, 50670 420 Recife, Brazil
Vet J 182:356-8. 2009..The use of such a sensitive, reproducible and rapid qPCR-based assay will be useful in the diagnosis and control of L. infantum infection in endemic areas, where serological surveys often underestimate true disease prevalence...
Discrimination of Leishmania braziliensis variants by kDNA signatures produced by LSSP-PCRGermano A Ferreira
Av Prof Moraes Rego, S N, Cidade Universitária 50670 420, Recife, Pernambuco, Brazil
J Parasitol 93:712-4. 2007....
Enhanced interleukin-12 and CD40 ligand activities but reduced Staphylococcus aureus Cowan 1-induced responses suggest a generalized and progressively impaired type 1 cytokine pattern for human schistosomiasisSilvia M L Montenegro
Departamento de Imunologia, , Recife, Brazil
Infect Immun 70:5903-12. 2002....
Evaluation of PCR for diagnosis of American cutaneous leishmaniasis in an area of endemicity in northeastern BrazilEduardo Henrique Gomes Rodrigues
, , Av. Prof. Moraes Rego s/n, , 50670-420 Recife, Brazil
J Clin Microbiol 40:3572-6. 2002..braziliensis. The evidence available at present incriminates L. braziliensis as the only causative agent of ACL in the state of Pernambuco in Brazil...
Partial molecular characterization of Sm8, a tegumental antigen of Schistosoma mansoniFrederico G C Abath
, FIOCRUZ, Recife, PE, 50670-420, Brasil
Mem Inst Oswaldo Cruz 97:91-3. 2002..The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms...
Antibody isotype responses to egg antigens in human chronic Schistosomiasis mansoni before and after treatmentYara M Gomes
Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhaes, FIOCRUZ, Recife, PE, 50670 420, Brasil
Mem Inst Oswaldo Cruz 97:111-2. 2002..Our results suggest that schistosomiasis treatment would not interfere with this sort of immune response...
Treatment of human acute schistosomiasis with oxamniquine induces an increase in interferon-gamma response to Schistosoma mansoni antigensJoelma R de Souza
Departamento de Bioquimica, Universitaria, 52020 020 Recife, PE, Brasil
Mem Inst Oswaldo Cruz 102:225-8. 2007..The oxamniquine treatment of acute schistosomiasis patients is followed by an improvement of a Th1 response in vitro. If this response has a protective aspect is unknown, and some investigations need to be realized...
Persistence of leishmania parasites in scars after clinical cure of American cutaneous leishmaniasis: is there a sterile cure?Mitzi G Mendonça
Departamento de Dermatologia, Universidade Federal de Pernambuco, Recife, Brazil
J Infect Dis 189:1018-23. 2004..Recently, sensitive molecular techniques have allowed the identification of Leishmania parasites directly in specimens from patients' scars...
Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoniLilian Beck
Instituto Oswaldo Cruz FIOCRUZ, Rio de Janeiro, RJ, Brazil
Mem Inst Oswaldo Cruz 99:97-8. 2004..The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis...
