K L Haag

Summary

Affiliation: Porto Alegre
Country: Brazil

Publications

  1. ncbi Selection, recombination and history in a parasitic flatworm (Echinococcus) inferred from nucleotide sequences
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil
    Mem Inst Oswaldo Cruz 93:695-702. 1998
  2. ncbi Breeding systems in Echinococcus granulosus (Cestoda; Taeniidae): selfing or outcrossing?
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Parasitology 118:63-71. 1999
  3. ncbi Redundancy and recombination in the Echinococcus AgB multigene family: is there any similarity with protozoan contingency genes?
    K L Haag
    Department of Genetics, Institute of Biological Sciences, UFRGS, Porto Alegre, 91501 970 RS, Brazil
    Parasitology 133:411-9. 2006
  4. ncbi Reduced genetic variability within coding and non-coding regions of the Echinococcus multilocularis genome
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Parasitology 115:521-9. 1997
  5. ncbi Using mitochondrial and nuclear markers to evaluate the degree of genetic cohesion among Echinococcus populations
    J L Badaraco
    Programa de Pos Graduacao em Genetica e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, CEP 91501 970, Brazil
    Exp Parasitol 119:453-9. 2008
  6. ncbi Livestock trade history, geography, and parasite strains: the mitochondrial genetic structure of Echinococcus granulosus in Argentina
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, CEP 91501 970 Porto Alegre, RS, Brazil
    J Parasitol 90:234-9. 2004
  7. ncbi The Echinococcus granulosus antigen B shows a high degree of genetic variability
    A C Arend
    , Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, CEP 91501-970, Porto Alegre, RS, Brazil
    Exp Parasitol 108:76-80. 2004
  8. ncbi Searching for antigen B genes and their adaptive sites in distinct strains and species of the helminth Echinococcus
    K L Haag
    Departamento de Genetica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Av Bento Goncalves, 9500 Prédio 43323, Caixa Postal 15053, Porto Alegre, RS, CEP 91501 970, Brazil
    Infect Genet Evol 6:251-61. 2006
  9. ncbi Contingent, non-neutral evolution in a multicellular parasite: natural selection and gene conversion in the Echinococcus granulosus antigen B gene family
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Gene 333:157-67. 2004
  10. ncbi Expression and diversity of Echinococcus multilocularis AgB genes in secondarily infected mice: evaluating the influence of T-cell immune selection on antigenic variation
    D A S Graichen
    Programa de Pos Graduacao em Genetica e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Gene 392:98-105. 2007

Collaborators

Detail Information

Publications11

  1. ncbi Selection, recombination and history in a parasitic flatworm (Echinococcus) inferred from nucleotide sequences
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil
    Mem Inst Oswaldo Cruz 93:695-702. 1998
    ..The phylogenetic analyses revealed several ambiguities, indicating that the taxonomic status of the E. granulosus horse strain should be revised...
  2. ncbi Breeding systems in Echinococcus granulosus (Cestoda; Taeniidae): selfing or outcrossing?
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Parasitology 118:63-71. 1999
    ..We suggest that both processes are adaptive. The article also reports, for the first time, the occurrence of the E. granulosus cattle strain in South America...
  3. ncbi Redundancy and recombination in the Echinococcus AgB multigene family: is there any similarity with protozoan contingency genes?
    K L Haag
    Department of Genetics, Institute of Biological Sciences, UFRGS, Porto Alegre, 91501 970 RS, Brazil
    Parasitology 133:411-9. 2006
    ..These results are discussed in light of the role of gene redundancy and recombination in parasite evasion mechanisms of host immunity, which at present are known for protozoan organisms, but virtually unknown for multicellular parasites...
  4. ncbi Reduced genetic variability within coding and non-coding regions of the Echinococcus multilocularis genome
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Parasitology 115:521-9. 1997
    ..granulosus, we suggest that the conventional classification of the former species in 2 separated strains (European and North American) should be reviewed...
  5. ncbi Using mitochondrial and nuclear markers to evaluate the degree of genetic cohesion among Echinococcus populations
    J L Badaraco
    Programa de Pos Graduacao em Genetica e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, CEP 91501 970, Brazil
    Exp Parasitol 119:453-9. 2008
    ..The biologic and epidemiologic consequences of our findings are discussed...
  6. ncbi Livestock trade history, geography, and parasite strains: the mitochondrial genetic structure of Echinococcus granulosus in Argentina
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, CEP 91501 970 Porto Alegre, RS, Brazil
    J Parasitol 90:234-9. 2004
    ..Our results suggest that geographic patterns are not due to actual restricted gene flow between regions but are rather a consequence of past history, probably related to the time and origin of livestock introduction in Argentina...
  7. ncbi The Echinococcus granulosus antigen B shows a high degree of genetic variability
    A C Arend
    , Universidade Federal do Rio Grande do Sul, Caixa Postal 15053, CEP 91501-970, Porto Alegre, RS, Brazil
    Exp Parasitol 108:76-80. 2004
    ..The 45 bp segment encompasses the conserved splicing signals and corresponds to a highly conserved insect promoter motif...
  8. ncbi Searching for antigen B genes and their adaptive sites in distinct strains and species of the helminth Echinococcus
    K L Haag
    Departamento de Genetica, Instituto de Biociencias, Universidade Federal do Rio Grande do Sul, Av Bento Goncalves, 9500 Prédio 43323, Caixa Postal 15053, Porto Alegre, RS, CEP 91501 970, Brazil
    Infect Genet Evol 6:251-61. 2006
    ..No selection is detected in AgB2. We discuss implications of our findings in terms of AgB biology and its use as a diagnostic tool...
  9. ncbi Contingent, non-neutral evolution in a multicellular parasite: natural selection and gene conversion in the Echinococcus granulosus antigen B gene family
    K L Haag
    Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
    Gene 333:157-67. 2004
    ..Contingency genes are common in parasitic protozoa and other microparasites, but the EgAgB family is the first set identified in a multicellular parasite...
  10. ncbi Expression and diversity of Echinococcus multilocularis AgB genes in secondarily infected mice: evaluating the influence of T-cell immune selection on antigenic variation
    D A S Graichen
    Programa de Pos Graduacao em Genetica e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    Gene 392:98-105. 2007
    ..Together, these results pointed to the effect of purifying selection, which seemed to eliminate the detrimental AgB variants generated during the development of the metacestode within the peritoneal cavity of its intermediate host...
  11. ncbi Isolation and characterization of microsatellites from the tapeworm Echinococcus granulosus
    M L Bartholomei-Santos
    Centro de Biotecnologia e Departamento de Biologia Molecular e Biotecnologia, , Universidade Federal do Rio Grande do Sul, Caixa Postal 15.005, Porto Alegre 91.501-970, RS, Brazil
    Parasitology 126:599-605. 2003
    ..This work describes for the first time the isolation and characterization of microsatellites from E. granulosus...