Research Topics
Genomes and GenesSpecies | Ana Luisa Miranda-VilelaSummaryCountry: Brazil Publications
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Publications
Role of polymorphisms in factor V (FV Leiden), prothrombin, plasminogen activator inhibitor type-1 (PAI-1), methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) genes as risk factors for thrombophiliasA L Miranda-Vilela
Department of Genetics and Morphology, Laboratory of Genetics, Institute of Biological Sciences, University of Brasilia, Brasilia DF, Brazil
Mini Rev Med Chem 12:997-1006. 2012....
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levelsAna Luisa Miranda-Vilela
Laboratorio de Genetica, Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
Eur J Appl Physiol 112:941-50. 2012..The results indicate that these polymorphisms can indirectly influence performance, contribute to higher susceptibility to exercise-induced inflammation or protection against it, and perhaps affect future risks of CVD in athletes...
Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levelsAna Luisa Miranda-Vilela
Departamento de Genetica e Morfologia, Universidade de Brasilia, Brasilia, Brazil
Eur J Appl Physiol 112:183-92. 2012..Results indicate that these polymorphisms can indirectly influence performance, contribute to higher susceptibility to exercise-induced inflammation or protection against it, and perhaps affect future risks of CVD in athletes...
Genetic polymorphisms influence runners' responses to the dietary ingestion of antioxidant supplementation based on pequi oil (Caryocar brasiliense Camb.): a before-after studyAna Luisa Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
Genes Nutr 6:369-95. 2011..Knowledge is also expanded on how antioxidant supplementation affects an individual's genes and how athletic genetic makeup can affect the way a person responds to antioxidant supplements...
The protective effects of nutritional antioxidant therapy on Ehrlich solid tumor-bearing mice depend on the type of antioxidant therapy chosen: histology, genotoxicity and hematology evaluationsAna Luisa Miranda-Vilela
Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brasil
J Nutr Biochem 22:1091-8. 2011....
Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control studyA L Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brasil
Genet Mol Res 9:2166-75. 2010..However, a possible association with Hp1-1 and MnSOD Val/Ala genotypes suggests that, at least for the Brazilian population, polymorphisms related to oxidative stress should be more deeply investigated...
The effect of hydrogen peroxide-induced oxidative stress on leukocytes depends on age and physical training in healthy human subjects carrying the same genotypes of antioxidant enzymes' gene polymorphismsAna Luisa Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Campus Universitario Darcy Ribeiro, Brasilia DF, Brazil
Am J Hum Biol 22:807-12. 2010....
Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental studyAna L Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brasil
Environ Health 9:21. 2010....
Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9AlaA L Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brasil
Genet Mol Res 8:1481-95. 2009....
Pequi fruit (Caryocar brasiliense Camb.) pulp oil reduces exercise-induced inflammatory markers and blood pressure of male and female runnersAna L Miranda-Vilela
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, 70910 900 Brasília DF, Brasil
Nutr Res 29:850-8. 2009..However, this finding needs additional investigation. Thus, pequi oil, besides possessing many nutritional properties, may be a good candidate supplement for athletes...
Evaluation of gene polymorphisms in exercise-induced oxidative stress and damageArthur Kenji Akimoto
Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brazil
Free Radic Res 44:322-31. 2010..Higher or lower TBARS and CK values or DNA damage also depended on the interaction between Hp and ACE or GST genotypes, indicating that MnSOD and Hp polymorphisms can be determining factors in performance, at least for runners...
Preliminary biocompatibility investigation of magnetic albumin nanosphere designed as a potential versatile drug delivery systemLuciana Estevanato
Instituto de Ciencias Biologicas, Universidade de Brasilia, 70910 900, Brasilia DF, Brazil
Int J Nanomedicine 6:1709-17. 2011..It is noteworthy that MAN was efficient in treating Ehrlich's tumors by the magnetohyperthermia procedure...
Antioxidant effect of haptoglobin phenotypes against DNA damage induced by hydrogen peroxide in human leukocytesL R S Moreira
Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
Genet Mol Res 8:284-90. 2009..The Hp1-1 genotype had the least DNA damage; this indicates that Hp alleles differ in their protective effects against oxidative damage. Among Hp*1 alleles, Hp*1F was the most protective...
