Ana Luisa Miranda-Vilela

Summary

Country: Brazil

Publications

  1. pmc Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners: influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia (sports anemia)
    Ana L Miranda-Vilela
    Laboratorio de Genetica, Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF Brazil
    Genet Mol Biol 33:359-67. 2010
  2. pmc Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups
    Cássia de Oliveira Hiragi
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Genet Mol Biol 34:11-8. 2011
  3. pmc Haptoglobin gene subtypes in three Brazilian population groups of different ethnicities
    Ana L Miranda-Vilela
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF Brazil
    Genet Mol Biol 32:456-61. 2009
  4. ncbi request reprint Dextran-functionalized magnetic fluid mediating magnetohyperthermia for treatment of Ehrlich-solid-tumor-bearing mice: toxicological and histopathological evaluations
    Ana Luisa Miranda-Vilela
    Institute of Biological Sciences, Department of Genetics and Morphology, University of Brasilia, Brasilia, Brazil
    Tumour Biol 35:3391-403. 2014
  5. ncbi request reprint Dextran-functionalized magnetic fluid mediating magnetohyperthermia combined with preventive antioxidant pequi-oil supplementation: potential use against cancer
    Ana Luisa Miranda-Vilela
    Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasília 70910 900, Brazil
    J Biomed Nanotechnol 9:1261-71. 2013
  6. ncbi request reprint Role of polymorphisms in factor V (FV Leiden), prothrombin, plasminogen activator inhibitor type-1 (PAI-1), methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) genes as risk factors for thrombophilias
    A L Miranda-Vilela
    Department of Genetics and Morphology, Laboratory of Genetics, Institute of Biological Sciences, University of Brasilia, Brasilia DF, Brazil
    Mini Rev Med Chem 12:997-1006. 2012
  7. doi request reprint Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels
    Ana Luisa Miranda-Vilela
    Laboratorio de Genetica, Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Eur J Appl Physiol 112:941-50. 2012
  8. doi request reprint The effect of hydrogen peroxide-induced oxidative stress on leukocytes depends on age and physical training in healthy human subjects carrying the same genotypes of antioxidant enzymes' gene polymorphisms
    Ana Luisa Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Campus Universitario Darcy Ribeiro, Brasilia DF, Brazil
    Am J Hum Biol 22:807-12. 2010
  9. doi request reprint Pequi fruit (Caryocar brasiliense Camb.) pulp oil reduces exercise-induced inflammatory markers and blood pressure of male and female runners
    Ana L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, 70910 900 Brasília DF, Brasil
    Nutr Res 29:850-8. 2009
  10. doi request reprint Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9Ala
    A L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brasil
    Genet Mol Res 8:1481-95. 2009

Collaborators

  • C K Grisolia
  • Raimunda Nonata Ribeiro Sampaio
  • Ricardo Bentes Azevedo
  • Ana Hatagima
  • Ieler Ferreira Ribeiro
  • Antonio Claudio Tedesco
  • Maria de Nazaré Klautau-Guimarães
  • Olímpia Paschoal Martins
  • Flávia Arruda Portilho
  • Ricardo Fontoura de Carvalho
  • Zulmira Guerrero Marques Lacava
  • Cássia de Oliveira Hiragi
  • Luciana Estevanato
  • Arthur Kenji Akimoto
  • L R S Moreira
  • Paulo Cesar Morais
  • Luciana Landim Carneiro Estevanato
  • João Paulo Figueiró Longo
  • Anamélia Lorenzetti Bocca
  • Maria de Fátima Menezes Almeida Santos
  • José de Souza Filho
  • Sônia Nair Báo
  • Débora de Oliveira Cintra e Silva
  • Cláudio Eduardo de Oliveira Cavalcanti
  • Andreza R Simioni
  • Zulmira G M Lacava
  • Olímpia Martins
  • Paulo C Morais
  • Nayara Baldini
  • Débora Cintra
  • Luzirlane Barbosa
  • Flávia Portilho
  • Silviene Fabiana de Oliveira
  • Dulce Maria Sucena Rocha
  • Sônia Báo
  • Bruno Lacava
  • Luiz Carlos da Silva Pereira
  • Penha Cristina Zaidan Alves
  • Izabel Cristina Rodrigues da Silva
  • Cassia de Oliveira Hiragi
  • Graciana Souza Lordelo
  • I C R Silva
  • A K Akimoto
  • M N Klautau-Guimarães

Detail Information

Publications21

  1. pmc Dietary carotenoid-rich oil supplementation improves exercise-induced anisocytosis in runners: influences of haptoglobin, MnSOD (Val9Ala), CAT (21A/T) and GPX1 (Pro198Leu) gene polymorphisms in dilutional pseudoanemia (sports anemia)
    Ana L Miranda-Vilela
    Laboratorio de Genetica, Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF Brazil
    Genet Mol Biol 33:359-67. 2010
    ..The significantly lower RDW and higher MHCH values were related to pequi-oil protective effects. Pequi oil, besides possessing other nutritional properties, showed protective blood effects...
  2. pmc Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups
    Cássia de Oliveira Hiragi
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Genet Mol Biol 34:11-8. 2011
    ..If these studies are designed to comprehensively explore the role of these genetic polymorphisms in the etiology of human diseases they may help to prevent inconsistent genotype-phenotype associations in pharmacogenetic studies...
  3. pmc Haptoglobin gene subtypes in three Brazilian population groups of different ethnicities
    Ana L Miranda-Vilela
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF Brazil
    Genet Mol Biol 32:456-61. 2009
    ..0291) indicated slight genetic differentiation among subpopulations of the general Brazilian population studied here. This is the first Brazilian report of variations in the Hp(*1F) and Hp(*1S) frequencies among non-Amerindian Brazilians...
  4. ncbi request reprint Dextran-functionalized magnetic fluid mediating magnetohyperthermia for treatment of Ehrlich-solid-tumor-bearing mice: toxicological and histopathological evaluations
    Ana Luisa Miranda-Vilela
    Institute of Biological Sciences, Department of Genetics and Morphology, University of Brasilia, Brasilia, Brazil
    Tumour Biol 35:3391-403. 2014
    ..Its physical characteristics also suggest that it is safe to use in other biomedical applications. ..
  5. ncbi request reprint Dextran-functionalized magnetic fluid mediating magnetohyperthermia combined with preventive antioxidant pequi-oil supplementation: potential use against cancer
    Ana Luisa Miranda-Vilela
    Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasília 70910 900, Brazil
    J Biomed Nanotechnol 9:1261-71. 2013
    ..Our findings evidence the potential use of DexMF mediating magnetohyperthermia in cancer treatment and also suggest that the preventive pequi oil administration could increase the efficiency of this process...
  6. ncbi request reprint Role of polymorphisms in factor V (FV Leiden), prothrombin, plasminogen activator inhibitor type-1 (PAI-1), methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) genes as risk factors for thrombophilias
    A L Miranda-Vilela
    Department of Genetics and Morphology, Laboratory of Genetics, Institute of Biological Sciences, University of Brasilia, Brasilia DF, Brazil
    Mini Rev Med Chem 12:997-1006. 2012
    ....
  7. doi request reprint Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels
    Ana Luisa Miranda-Vilela
    Laboratorio de Genetica, Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Eur J Appl Physiol 112:941-50. 2012
    ..The results indicate that these polymorphisms can indirectly influence performance, contribute to higher susceptibility to exercise-induced inflammation or protection against it, and perhaps affect future risks of CVD in athletes...
  8. doi request reprint The effect of hydrogen peroxide-induced oxidative stress on leukocytes depends on age and physical training in healthy human subjects carrying the same genotypes of antioxidant enzymes' gene polymorphisms
    Ana Luisa Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Campus Universitario Darcy Ribeiro, Brasilia DF, Brazil
    Am J Hum Biol 22:807-12. 2010
    ....
  9. doi request reprint Pequi fruit (Caryocar brasiliense Camb.) pulp oil reduces exercise-induced inflammatory markers and blood pressure of male and female runners
    Ana L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, 70910 900 Brasília DF, Brasil
    Nutr Res 29:850-8. 2009
    ..However, this finding needs additional investigation. Thus, pequi oil, besides possessing many nutritional properties, may be a good candidate supplement for athletes...
  10. doi request reprint Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9Ala
    A L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brasil
    Genet Mol Res 8:1481-95. 2009
    ....
  11. doi request reprint Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-reactive protein levels
    Ana Luisa Miranda-Vilela
    Departamento de Genetica e Morfologia, Universidade de Brasilia, Brasilia, Brazil
    Eur J Appl Physiol 112:183-92. 2012
    ..Results indicate that these polymorphisms can indirectly influence performance, contribute to higher susceptibility to exercise-induced inflammation or protection against it, and perhaps affect future risks of CVD in athletes...
  12. pmc Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study
    Ana L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brasil
    Environ Health 9:21. 2010
    ....
  13. pmc Genetic polymorphisms influence runners' responses to the dietary ingestion of antioxidant supplementation based on pequi oil (Caryocar brasiliense Camb.): a before-after study
    Ana Luisa Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Genes Nutr 6:369-95. 2011
    ..Knowledge is also expanded on how antioxidant supplementation affects an individual's genes and how athletic genetic makeup can affect the way a person responds to antioxidant supplements...
  14. doi request reprint The protective effects of nutritional antioxidant therapy on Ehrlich solid tumor-bearing mice depend on the type of antioxidant therapy chosen: histology, genotoxicity and hematology evaluations
    Ana Luisa Miranda-Vilela
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brasil
    J Nutr Biochem 22:1091-8. 2011
    ....
  15. doi request reprint Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study
    A L Miranda-Vilela
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brasil
    Genet Mol Res 9:2166-75. 2010
    ..However, a possible association with Hp1-1 and MnSOD Val/Ala genotypes suggests that, at least for the Brazilian population, polymorphisms related to oxidative stress should be more deeply investigated...
  16. doi request reprint Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage
    Arthur Kenji Akimoto
    Departamento de Genetica e Morfologia, Laboratorio de Genetica, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia DF, Brazil
    Free Radic Res 44:322-31. 2010
    ..Higher or lower TBARS and CK values or DNA damage also depended on the interaction between Hp and ACE or GST genotypes, indicating that MnSOD and Hp polymorphisms can be determining factors in performance, at least for runners...
  17. pmc Antitumor activity of photodynamic therapy performed with nanospheres containing zinc-phthalocyanine
    Flávia Arruda Portilho
    Instituto de Ciencias Biologicas, Departamento de Genetica e Morfologia, Universidade de Brasilia, CEP 70910 970 Brasília, DF, Brazil
    J Nanobiotechnology 11:41. 2013
    ....
  18. doi request reprint Leishmanicidal activity of amphotericin B encapsulated in PLGA-DMSA nanoparticles to treat cutaneous leishmaniasis in C57BL/6 mice
    Ricardo Fontoura de Carvalho
    Faculdade de Ciencias da Saude, Laboratório de Dermatomicologia, Universidade de Brasilia, 70910 900 Brasilia, Brazil
    Exp Parasitol 135:217-22. 2013
    ..It thus favors a longer interval between doses, as expected with development of a new nano drug delivery system, and may be useful in the treatment of many different pathologies, from cancer to neurodegenerative diseases...
  19. ncbi request reprint The influence of erythropoietin (EPO T → G) and α-actinin-3 (ACTN3 R577X) polymorphisms on runners' responses to the dietary ingestion of antioxidant supplementation based on pequi oil ( Caryocar brasiliense Camb.): a before-after study
    Ieler Ferreira Ribeiro
    Department of Genetics and Morphology, Institute of Biological Sciences, University of Brasilia, Brasilia, Brazil
    J Nutrigenet Nutrigenomics 6:283-304. 2013
    ....
  20. pmc Preliminary biocompatibility investigation of magnetic albumin nanosphere designed as a potential versatile drug delivery system
    Luciana Estevanato
    Instituto de Ciencias Biologicas, Universidade de Brasilia, 70910 900, Brasilia DF, Brazil
    Int J Nanomedicine 6:1709-17. 2011
    ..It is noteworthy that MAN was efficient in treating Ehrlich's tumors by the magnetohyperthermia procedure...
  21. ncbi request reprint Antioxidant effect of haptoglobin phenotypes against DNA damage induced by hydrogen peroxide in human leukocytes
    L R S Moreira
    Departamento de Genetica e Morfologia, Instituto de Ciencias Biologicas, Universidade de Brasilia, Brasilia, DF, Brazil
    Genet Mol Res 8:284-90. 2009
    ..The Hp1-1 genotype had the least DNA damage; this indicates that Hp alleles differ in their protective effects against oxidative damage. Among Hp*1 alleles, Hp*1F was the most protective...