Geraldo Lorenzi-Filho

Summary

Country: Brazil

Publications

  1. pmc Effects of intravenous furosemide on mucociliary transport and rheological properties of patients under mechanical ventilation
    Cláudia Seiko Kondo
    Universidade de Sao Paulo, Sao Paulo, Brazil
    Crit Care 6:81-7. 2002
  2. ncbi [Cardiovascular consequences of obstructive sleep apnea syndrome]
    Geraldo Lorenzi Filho
    Disciplina de Pneumologia, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    J Bras Pneumol 36:38-42. 2010
  3. pmc Obstructive sleep apnea: an emerging risk factor for atherosclerosis
    Luciano F Drager
    Hypertension Unit, Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Chest 140:534-42. 2011
  4. ncbi Cheyne-Stokes respiration in patients with congestive heart failure: causes and consequences
    Geraldo Lorenzi-Filho
    Heart Institute, Faculty of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 60:333-44. 2005
  5. doi Time delay of baroreflex control and oscillatory pattern of sympathetic activity in patients with metabolic syndrome and obstructive sleep apnea
    Edgar Toschi-Dias
    Heart Institute Instituto do Coração University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Physiol Heart Circ Physiol 304:H1038-44. 2013
  6. pmc Obstructive sleep apnea is associated with increased chemoreflex sensitivity in patients with metabolic syndrome
    Ivani C Trombetta
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Sleep 36:41-9. 2013
  7. pmc The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    PLoS ONE 5:e12065. 2010
  8. doi Obstructive sleep apnea: the most common secondary cause of hypertension associated with resistant hypertension
    Rodrigo P Pedrosa
    Sleep Laboratory, Pulmonary Division, Heart Institute, Av Enéas Carvalho de Aguiar 44, Sao Paulo, Brazil
    Hypertension 58:811-7. 2011
  9. doi The effects of continuous positive airway pressure on prehypertension and masked hypertension in men with severe obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, 05403 904 São Paulo, Brazil
    Hypertension 57:549-55. 2011
  10. ncbi Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodeling
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, CEP 05403 904, Sao Paulo, Brazil
    Chest 131:1379-86. 2007

Collaborators

Detail Information

Publications70

  1. pmc Effects of intravenous furosemide on mucociliary transport and rheological properties of patients under mechanical ventilation
    Cláudia Seiko Kondo
    Universidade de Sao Paulo, Sao Paulo, Brazil
    Crit Care 6:81-7. 2002
    ..The remaining parameters did not change significantly in either group. Our results support the hypothesis that IV furosemide might acutely impair MCT in patients under MV...
  2. ncbi [Cardiovascular consequences of obstructive sleep apnea syndrome]
    Geraldo Lorenzi Filho
    Disciplina de Pneumologia, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    J Bras Pneumol 36:38-42. 2010
    ....
  3. pmc Obstructive sleep apnea: an emerging risk factor for atherosclerosis
    Luciano F Drager
    Hypertension Unit, Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Chest 140:534-42. 2011
    ..This review provides an update on the role of OSA in atherogenesis and highlights future perspectives in this important research area...
  4. ncbi Cheyne-Stokes respiration in patients with congestive heart failure: causes and consequences
    Geraldo Lorenzi-Filho
    Heart Institute, Faculty of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 60:333-44. 2005
    ..Cheyne-Stokes respiration is an independent marker of poor prognosis and may participate in a vicious cycle, further stressing the failing heart...
  5. doi Time delay of baroreflex control and oscillatory pattern of sympathetic activity in patients with metabolic syndrome and obstructive sleep apnea
    Edgar Toschi-Dias
    Heart Institute Instituto do Coração University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Physiol Heart Circ Physiol 304:H1038-44. 2013
    ..001). In conclusion, MetS decreases the oscillatory pattern of MSNA and the magnitude of the ABRMSNA. OSA exacerbates these autonomic dysfunctions and further increases the time delay of the baroreflex response of MSNA...
  6. pmc Obstructive sleep apnea is associated with increased chemoreflex sensitivity in patients with metabolic syndrome
    Ivani C Trombetta
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Sleep 36:41-9. 2013
    ..However, the mechanisms involved in sympathetic hyperactivation in patients with MetS + OSA remain to be clarified. We tested the hypothesis that chemoreflex sensitivity is heightened in patients with MetS and OSA...
  7. pmc The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    PLoS ONE 5:e12065. 2010
    ..Therefore, it is not clear whether OSA exacerbates the metabolic abnormalities in a representative sample of patients with MetS...
  8. doi Obstructive sleep apnea: the most common secondary cause of hypertension associated with resistant hypertension
    Rodrigo P Pedrosa
    Sleep Laboratory, Pulmonary Division, Heart Institute, Av Enéas Carvalho de Aguiar 44, Sao Paulo, Brazil
    Hypertension 58:811-7. 2011
    ..Age >50 years, large neck circumference measurement, and snoring are good predictors of obstructive sleep apnea in this population...
  9. doi The effects of continuous positive airway pressure on prehypertension and masked hypertension in men with severe obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, 05403 904 São Paulo, Brazil
    Hypertension 57:549-55. 2011
    ..In conclusion, effective CPAP therapy promotes significant reduction in the frequency of prehypertension and masked hypertension by promoting significant blood pressure reductions in patients with severe obstructive sleep apnea...
  10. ncbi Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodeling
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, CEP 05403 904, Sao Paulo, Brazil
    Chest 131:1379-86. 2007
    ..We sought to investigate the impact of OSA, hypertension, and their association with arterial stiffness and heart structure...
  11. ncbi Early signs of atherosclerosis in obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit and Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 900 São Paulo, Brazil
    Am J Respir Crit Care Med 172:613-8. 2005
    ..Recent studies have shown that OSA is associated with multiple markers of endothelial damage. We hypothesized that OSA affects functional and structural properties of large arteries, contributing to atherosclerosis progression...
  12. doi Characteristics and predictors of obstructive sleep apnea in patients with systemic hypertension
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Sao Paulo, Brazil
    Am J Cardiol 105:1135-9. 2010
    ....
  13. pmc Consequences of comorbid sleep apnea in the metabolic syndrome--implications for cardiovascular risk
    Ivani C Trombetta
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Sleep 33:1193-9. 2010
    ..We examined how the presence of OSA in patients with MetSyn affected hemodynamic and autonomic variables associated with poor cardiovascular outcome...
  14. doi The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 904, Sao Paulo, Brazil
    Atherosclerosis 208:490-5. 2010
    ..The main objective of this study is to determine the impact of OSA on markers of atherosclerosis in patients with MS...
  15. doi Sleep quality and quality of life in patients with hypertrophic cardiomyopathy
    Rodrigo P Pedrosa
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, Hospital das Clinicas da Faculdade de Medicina, Universidade de Sao Paulo, Av Enéas Carvalho de Aguiar 44, Sao Paulo, Brazil
    Cardiology 117:200-6. 2010
    ..To evaluate clinical predictors of poor sleep quality and quality of life (QOL) in patients with hypertrophic cardiomyopathy (HCM)...
  16. doi Arousals are frequent and associated with exacerbated blood pressure response in patients with primary hypertension
    Carlos E V Garcia
    Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Am J Hypertens 26:617-23. 2013
    ..We sought to investigate the frequency and magnitude of blood pressure (BP) increases triggered by spontaneous arousals in patients with primary hypertension...
  17. doi Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Am Coll Cardiol 62:569-76. 2013
    ..Taken together, these results support the concept that OSA exacerbates the cardiometabolic risk attributed to obesity and the metabolic syndrome. Recognition and treatment of OSA may decrease the cardiovascular risk in obese patients. ..
  18. doi Day-night pattern of autonomic nervous system modulation in patients with heart failure with and without sleep apnea
    Linda M Ueno
    School of Arts, Sciences and Humanities, University of Sao Paulo, Sao Paulo, Brazil
    Int J Cardiol 148:53-8. 2011
    ..However, the day-night pattern of cardiac autonomic nervous system modulation in CHF patients with and without sleep apnea is unknown...
  19. doi Lack of circadian variation of pulse wave velocity measurements in healthy volunteers
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Clin Hypertens (Greenwich) 13:19-22. 2011
    ..016). In young healthy volunteers, there is no significant circadian variation of carotid-femoral PWV. These findings support the concept that it does not appear mandatory to perform PWV measurements at exactly the same period of the day...
  20. doi Obstructive sleep apnea and hypertrophic cardiomyopathy: a common and potential harmful combination
    Flávia B Nerbass
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo School of Medicine, Brazil
    Sleep Med Rev 17:201-6. 2013
    ..Therefore, the recognition of OSA is a new area of research that may impact the management of patients with HCM...
  21. doi Obstructive sleep apnea is common and independently associated with atrial fibrillation in patients with hypertrophic cardiomyopathy
    Rodrigo P Pedrosa
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, Av Enéas Carvalho de Aguiar, 44, Sao Paulo, Brazil
    Chest 137:1078-84. 2010
    ..Obstructive sleep apnea (OSA) is independently associated with heart remodeling and arrhythmias in other populations. We hypothesized that OSA is common and is associated with heart remodeling and AF in patients with HCM...
  22. doi Obstructive sleep apnea, masked hypertension, and arterial stiffness in men
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Hypertens 23:249-54. 2010
    ..However, it is not clear whether the frequency of masked hypertension in patients with OSA and whether OSA have an independent role on arterial stiffness taking into account ambulatory blood pressure (BP) monitoring (ABPM)...
  23. doi Sleep desaturation and its relationship to lung function, exercise and quality of life in LAM
    Pedro Medeiros
    Interstitial Lung Disease Group, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo 05403 900, SP, Brazil
    Respir Med 106:420-8. 2012
    ..Although sleep may trigger hypoxaemia in patients with airway obstruction, it has not been previously investigated in patients with LAM...
  24. doi Calcium channel blockers are independently associated with short sleep duration in hypertensive patients with obstructive sleep apnea
    Flávia B Nerbass
    Sleep Laboratory, Pulmonary Division, Brazil
    J Hypertens 29:1236-41. 2011
    ..The aim of this study was to evaluate the potential influence of antihypertensive medication on sleep parameters objectively measured by standard polysomnography in hypertensive patients with OSA...
  25. doi Obstructive sleep apnea is common among patients referred for coronary artery bypass grafting and can be diagnosed by portable monitoring
    Naury de Jesus Danzi-Soares
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Coron Artery Dis 23:31-8. 2012
    ....
  26. doi Additive effects of obstructive sleep apnea and hypertension on early markers of carotid atherosclerosis
    Luciano F Drager
    Hypertension Unit, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Hypertension 53:64-9. 2009
    ....
  27. doi Effects of cyclosporine A and bronchial transection on mucociliary transport in rats
    Rogerio Pazetti
    Laboratory of Thoracic Surgery Research, Department of Cardiopneumology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil
    Ann Thorac Surg 85:1925-9; discussion 1929. 2008
    ..We hypothesized that bronchial transection and immunosuppression by cyclosporine both play a key role in the impairment of airway mucociliary clearance, a basic defense system...
  28. pmc Lack of reliable clinical predictors to identify obstructive sleep apnea in patients with hypertrophic cardiomyopathy
    Flávia B Nerbass
    Faculdade de Medicina, Heart Institute InCor, Hospital das Cínicas, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 68:992-6. 2013
    ..However, obstructive sleep apnea is largely unrecognized in this population. We sought to identify the clinical predictors of obstructive sleep apnea among patients with hypertrophic cardiomyopathy...
  29. doi Reciprocal interactions of obstructive sleep apnea and hypertension associated with ACE I/D polymorphism in males
    Renata G Koyama
    Department of Psychobiology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Sleep Med 10:1107-11. 2009
    ..However, ACE is a pleiotropic gene that has several influences, including skeletal muscle and control of ventilation. We therefore tested the hypothesis that ACE polymorphism influences OSA severity...
  30. doi Effects of biomass burning on nasal mucociliary clearance and mucus properties after sugarcane harvesting
    Danielle Miyuki Goto
    Department of Physiotherapy, Communication Science and Disorders, Occupational Therapy, LIM 34, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
    Environ Res 111:664-9. 2011
    ..However, sugarcane harvesting is mostly performed after biomass burning. The aim of this study was to evaluate the effects of harvesting after biomass burning on nasal mucociliary clearance and the nasal mucus properties of farm workers...
  31. ncbi Acute cardiopulmonary alterations induced by fine particulate matter of São Paulo, Brazil
    Dolores Helena Rodriguez Ferreira Rivero
    Department of Pathology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Toxicol Sci 85:898-905. 2005
    ..Pulmonary vasculature was markedly affected by particle instillation, resulting in significant vasoconstriction in healthy rats...
  32. doi Cardiovascular effects of partial sleep deprivation in healthy volunteers
    Josilene L Dettoni
    Sleep Laboratory of Pulmonary Division of Heart Institute, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil
    J Appl Physiol (1985) 113:232-6. 2012
    ..These results may help to explain the association between short sleep and increased cardiovascular risk in epidemiological studies...
  33. doi Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome
    Kátia C Guimarães
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 904, Sao Paulo, Brazil
    Am J Respir Crit Care Med 179:962-6. 2009
    ..Preliminary results suggested that oropharyngeal exercises derived from speech therapy may be an effective treatment option for patients with moderate OSAS...
  34. ncbi [Reduction of central sleep apnea in heart failure patients with beta-blockers therapy]
    Christiano Pereira Silva
    Instituto do Coracao, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    Arq Bras Cardiol 94:223-9, 239-45, 226-32. 2010
    ..Sleep apneas are frequent in patients with heart failure (HF). Estimate of the pre-beta blocker age (BB) point out to 45% of central apneas in these patients...
  35. pmc Effects of exercise training in patients with chronic heart failure and sleep apnea
    Linda M Ueno
    School of Arts, Sciences and Humanities, University of Sao Paulo, Sao Paulo, Brazil
    Sleep 32:637-47. 2009
    ..To test the effects of exercise training on sleep and neurovascular control in patients with systolic heart failure with and without sleep disordered breathing...
  36. doi Nasal mucus transportability in children with cleft palate
    Sergio Henrique Kiemle Trindade
    Laboratory of Experimental Air Pollution, School of Medicine, University of Sao Paulo, Sao Paulo, SP, Brazil
    Int J Pediatr Otorhinolaryngol 72:581-5. 2008
    ..Considering that nasal mucus properties play a pivotal role in the upper airway defense mechanism, the aim of the study was to evaluate nasal mucus transportability and physical properties from children with CP...
  37. pmc Critical closing pressure during midazolam-induced sleep
    Pedro R Genta
    Pulmonary Division, Heart Institute InCor, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
    J Appl Physiol (1985) 111:1315-22. 2011
    ..Pcrit determined during the day with sleep induction is similar to natural overnight sleep and is a valid alternative approach in which to determine Pcrit...
  38. doi Comparison of full versus short induced-sleep polysomnography for the diagnosis of sleep apnea
    Marcelo G Gregório
    Sleep Laboratory, Pulmonary Division Heart Institute Incor University of São Paulo Medical School, Brazil
    Laryngoscope 121:1098-103. 2011
    ..However, the gap between demand and capacity in performing PSG is a major health-care problem. We sought to validate a short day-time induced sleep for the diagnosis of OSA...
  39. ncbi Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema
    Marcelo Park
    Division of Emergency Medicine, Heart Institute InCor, Hospital das Clinicas, University of Sao Paulo, Brazil
    Crit Care Med 32:2407-15. 2004
    ..To compare the effects of oxygen, continuous positive airway pressure (CPAP), and bilevel positive airway pressure (bilevel-PAP) on the rate of endotracheal intubation in patients with acute cardiogenic pulmonary edema...
  40. ncbi Luffa operculata affects mucociliary function of the isolated frog palate
    Mônica Aidar Menon-Miyake
    Department of Otorhinolaryngology, University of Sao Paulo, Sao Paulo, SP, Brazil
    Am J Rhinol 19:353-7. 2005
    ..Given the growing popularity of alternative medicine, a decision was made to evaluate the effects of this substance on mucous membranes...
  41. pmc Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
    Cristiana Marques de Araujo
    Departament of Clinical Cardiology, Instituto do Coração do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo São Paulo SP, Brazil
    Clinics (Sao Paulo) 64:223-30. 2009
    ..There is controversy regarding whether obstructive sleep apnea is responsible for triggering myocardial ischemia, arrhythmias and heart rate variability in patients with coronary artery disease...
  42. doi Furosemide impairs nasal mucociliary clearance in humans
    Danielle M Goto
    Department of Physiotherapy, Communication Science and Disorders, Occupational Therapy, LIM 34, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
    Respir Physiol Neurobiol 170:246-52. 2010
    ..In conclusion, furosemide prolongs STT in healthy young subjects. This effect is not prevented by fluid replacement, suggesting a direct effect of furosemide on the respiratory epithelium...
  43. ncbi Sputum induction as a research tool for the study of human respiratory mucus
    Claudia S Albertini-Yagi
    Division of Respiratory Diseases, Heart Institution InCor HC, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
    Respir Physiol Neurobiol 145:101-10. 2005
    ..025). (4) Rheological properties (no significant difference obtained between SI and DC). These results indicated that SI changes mucus physical properties and transportability in non-expectorators...
  44. doi Sleep in patients with large pleural effusion: impact of thoracentesis
    Bianca Fernandes Marcondes
    Sleep Laboratory, Pulmonary Division Heart Institute InCor, University of Sao Paulo, Av Doutor Altino Arantes, 648, apt 163, Vila Clemetino, Sao Paulo, SP, Brazil, CEP 04042 003
    Sleep Breath 16:483-9. 2012
    ..This study aimed to evaluate the sleep quality and impact of thoracentesis on sleep in patients with a large pleural effusion...
  45. doi Obstructive sleep apnea in patients on conventional and short daily hemodialysis
    Rosilene Motta Elias
    Division of Nephrology, Hospital das Clinicas, Universtiy of São Paulo School of Medicine, Sao Paulo, Brazil
    Am J Nephrol 29:493-500. 2009
    ..Among these patients, OSA is associated with difficult BP control and heart remodeling suggesting that OSA may contribute to poor cardiovascular outcome...
  46. ncbi Short-term effects of nCPAP on nasal mucociliary clearance and mucus transportability in healthy subjects
    Luciana R de Oliveira
    Experimental Air Pollution Laboratory, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Respir Med 100:183-5. 2006
    ..62 min; P=0.70). Mucus transportability was not significantly affected by nCPAP. Our results suggest that nCPAP can acutely increase nasal mucociliary clearance but does not affect in vitro mucus transportability in healthy subjects...
  47. ncbi Prevalence of excessive daytime sleepiness and associated factors in women aged 35-49 years from the "Pindamonhangaba Health Project" (PROSAPIN)
    Elaine Cristina Alves Pereira
    Universitária Vida Cristã, Sao Paulo, Brazil
    Rev Assoc Med Bras 58:447-52. 2012
    ..To estimate the prevalence of excessive daytime sleepiness (EDS) and to identify associated factors in women aged 35 to 49 years from the "Pindamonhangaba Health Project" (PROSAPIN)...
  48. doi Salbutamol improves markers of epithelial function in mice with chronic allergic pulmonary inflammation
    Alessandra C Toledo
    Department of Medicine, Laboratory of Experimental Therapeutics, LIM 20, University of Sao Paulo, Medical School, Sao Paulo, Sao Paulo, Brazil
    Respir Physiol Neurobiol 177:155-61. 2011
    ..This effect may have a positive impact on airway mucociliary transport in asthma and may have clinical implications...
  49. pmc The use of nasal dilator strips as a placebo for trials evaluating continuous positive airway pressure
    Aline C S Amaro
    Faculdade de Medicina, Universidade de Sao Paulo, Brazil
    Clinics (Sao Paulo) 67:469-74. 2012
    ..The aim of the current study was to compare the objective and subjective effects of continuous positive airway pressure to the use of nasal dilator strips in patients with acromegaly and moderate to severe obstructive sleep apnea...
  50. doi Sleep-related changes in hemodynamic and autonomic regulation in human hypertension
    Luciano F Drager
    Hypertension Unit Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, Zip Code 05403 904, Sao Paulo, Brazil
    J Hypertens 27:1655-63. 2009
    ..The present study investigates the hemodynamic and autonomic regulation during sleep-awake transitions and across different sleep cycles in patients with essential hypertension...
  51. ncbi Cyclosporin A reduces airway mucus secretion and mucociliary clearance in rats
    Rogerio Pazetti
    Thoracic Surgery Service, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 62:345-52. 2007
    ..To assay the effects of cyclosporin A on mucus secretion from goblet cells and on mucociliary transport in situ in rats...
  52. ncbi Pharyngeal dimensions in healthy men and women
    Mauro Miguel Daniel
    Department of Radiology, Neuroradiology Division, Sao Paulo University Medical School, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 62:5-10. 2007
    ..Epidemiological studies reveal a high male prevalence of obstructive sleep apnea syndrome. A possible explanation for this male predominance is the existence of anatomical differences in the upper airway between men and women...
  53. pmc Observational study on efficacy of negative expiratory pressure test proposed as screening for obstructive sleep apnea syndrome among commercial interstate bus drivers--protocol study
    Raquel P Hirata
    Master s and Doctoral Degree Programs in Rehabilitation Sciences, Nove de Julho, University, Sao Paulo, Brazil
    BMC Pulm Med 11:57. 2011
    ..2 s during the application of negative expiratory pressure (NEP) are associated with the presence and severity of OSA in a population of professional interstate bus drivers who travel medium and long distances...
  54. ncbi Periodic breathing during incremental exercise predicts mortality in patients with chronic heart failure evaluated for cardiac transplantation
    Joao J Leite
    Division of Respiratory Disease Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Am Coll Cardiol 41:2175-81. 2003
    ..We hypothesized that exercise-related periodic breathing (EPB) would be associated with poor prognosis in advanced chronic heart failure (CHF)...
  55. pmc Effects of massage therapy on sleep quality after coronary artery bypass graft surgery
    Flavia Baggio Nerbass
    Instituto do Coracao, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil
    Clinics (Sao Paulo) 65:1105-10. 2010
    ..Having poor sleep quality is common among patients following cardiopulmonary artery bypass graft surgery. Pain, stress, anxiety and poor sleep quality may be improved by massage therapy...
  56. ncbi PM(2.5) induces acute electrocardiographic alterations in healthy rats
    Dolores Helena Rodriguez Ferreira Rivero
    Experimental Air Pollution Laboratory, Department of Pathology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Environ Res 99:262-6. 2005
    ..5) of 50 and 100 microg. In conclusion, the injection of an aqueous suspension of PM(2.5) induced a reduction of SDNN in healthy rats. The effect was observed 1h after instillation and in a concentration of <100 microg...
  57. ncbi Mucociliary clearance is impaired in acutely ill patients
    Naomi Kondo Nakagawa
    University of São Paulo City UNICID, Sao Paulo, Brazil
    Chest 128:2772-7. 2005
    ..This study aimed to investigate nasal mucociliary clearance in acutely ill patients who were clinically stable and had no airway manipulation...
  58. doi Obstructive sleep apnea is highly prevalent and correlates with impaired glycemic control in consecutive patients with the metabolic syndrome
    Luciano F Drager
    Hypertension Unit, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Cardiometab Syndr 4:89-95. 2009
    ..001) and apnea-hypopnea index (P=.03). The prevalence of OSA is in the same range as all the individual components of MS and is independently associated with impaired glycemic control...
  59. doi The impact of sleep apnea treatment on carbohydrate metabolism in patients with acromegaly
    Felipe Henning Gaia Duarte
    Neuroendocrine Unit, Division of Endocrinology and Metabolism, Hospital das Clinicas, University of Sao Paulo Medical School, Av Dr Eneas de Carvalho, 255, 7ºandar, sala 7037, Instituto Central, Cerqueira Cesar, Sao Paulo, CEP 05403 000, Brazil
    Pituitary 16:341-50. 2013
    ..Our results support the concept that sleep apnea plays an important role on glucose metabolism. Insulin resistance indexes were unable to detect this finding...
  60. pmc Yoga respiratory training improves respiratory function and cardiac sympathovagal balance in elderly subjects: a randomised controlled trial
    Danilo F Santaella
    Sleep Laboratory, Pneumology Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    BMJ Open 1:e000085. 2011
    ..Trial Registration CinicalTrials.gov identifier: NCT00969345; trial registry name: Effects of respiratory yoga training (Bhastrika) on heart rate variability and baroreflex, and quality of life of healthy elderly subjects...
  61. doi Effects of yoga and the addition of Tui Na in patients with fibromyalgia
    Gerson D da Silva
    Rheumatology Division and Pulmonary Division, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    J Altern Complement Med 13:1107-13. 2007
    ..This study aimed to verify whether techniques of yoga with and without the addition of Tui Na might improve pain and the negative impact of fibromyalgia (FMS) on patients' daily life...
  62. ncbi [Quality of sleep of climacteric women in São Paulo: some significant aspects]
    Carmen Lúcia Souza
    Departamento de Psicología Clínica, Istituto de Psicologia, Universidade de Sao Paulo, Rua Inhambu 1307, Moema, Sao Paulo, CEP 04520 010 Brazil
    Rev Assoc Med Bras 51:170-6. 2005
    ..To subjectively evaluate the quality of sleep in menopausal women (35 to 65 years of age)..
  63. ncbi Obstructive sleep apnea syndrome in truck drivers
    Lucia Castro Lemos
    University of São Paulo School of Public Health, Sao Paulo, SP, Brasil
    J Bras Pneumol 35:500-6. 2009
    ..To determine the prevalence of obstructive sleep apnea syndrome (OSAS), as well as to identify factors associated with a greater risk of developing OSAS, among truck drivers...
  64. ncbi Provocation of ventricular ectopy by cheyne-stokes respiration in patients with heart failure
    Richard S T Leung
    University of Toronto Centre for Sleep Medicine and Circadian Biology, Ontario, Canada
    Sleep 27:1337-43. 2004
    ..The objective of this study was to determine whether CSR-CSA directly provokes ventricular ectopy and, if so, whether it is associated with any particular phase of the CSR-CSA breathing cycle...
  65. ncbi Influence of Cheyne-Stokes respiration on cardiovascular oscillations in heart failure
    Richard S T Leung
    Toronto General Hospital UHN, NU 9 112, 200 Elizabeth Street, Toronto ON, M5G 2C4, Canada
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    ....
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