Pedro A Lemos

Summary

Country: Brazil

Publications

  1. pmc Hypotheses, rationale, design, and methods for prognostic evaluation of cardiac biomarker elevation after percutaneous and surgical revascularization in the absence of manifest myocardial infarction. A comparative analysis of biomarkers and cardiac magnet
    Whady Hueb
    Heart Institute of the University of Sao Paulo, Sao Paulo, Brazil
    BMC Cardiovasc Disord 12:65. 2012
  2. doi request reprint Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial
    Pedro A Lemos
    Heart Institute InCor, University of São Paulo Medical School USP, Sao Paulo, Brazil
    EuroIntervention 8:117-9. 2012
  3. ncbi request reprint Rationale and design for the PAINT randomized trial
    Pedro A Lemos
    Instituto do Coracao, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brasil
    Arq Bras Cardiol 93:547-53, 590-7. 2009
  4. ncbi request reprint Randomized evaluation of two drug-eluting stents with identical metallic platform and biodegradable polymer but different agents (paclitaxel or sirolimus) compared against bare stents: 1-year results of the PAINT trial
    Pedro A Lemos
    Catheterization Laboratory, Heart Institute InCor, University of São Paulo Medical School USP, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 74:665-73. 2009
  5. doi request reprint Early days of an ingenious aspirin and sirolimus-eluting stent
    Pedro A Lemos
    Heart Institute InCor University of Sao Paulo Medical School, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 72:195. 2008
  6. ncbi request reprint Angiographic segment size in patients referred for coronary intervention is influenced by constitutional, anatomical, and clinical features
    Pedro A Lemos
    Interventional Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Int J Cardiovasc Imaging 23:1-7. 2007
  7. ncbi request reprint Delayed intravascular catabolism of chylomicron-like emulsions is an independent predictor of coronary artery disease
    Andrei C Sposito
    Heart Institute InCor, University of Sao Paulo Medical School, Hospital, Av Dr Enéas Carvalho Aguiar 44, 1o andar, 5403 900 São Paulo, Brazil
    Atherosclerosis 176:397-403. 2004
  8. doi request reprint Dipyridamole stress and rest transmural myocardial perfusion ratio evaluation by 64 detector-row computed tomography
    Roberto C Cury
    Cardiovascular MR and CT Section, Heart Institute InCor, University of São Paulo Medical School and Heart Hospital HCOR, Sao Paulo, Brazil
    J Cardiovasc Comput Tomogr 5:443-8. 2011
  9. doi request reprint Additional value of dipyridamole stress myocardial perfusion by 64-row computed tomography in patients with coronary stents
    Tiago A Magalhães
    Cardiovascular MR and CT Section, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas de Carvalho Aguiar, 44 Andar AB, Cerqueira Cesar, Sao Paulo, 05403 000, Brazil
    J Cardiovasc Comput Tomogr 5:449-58. 2011
  10. ncbi request reprint Impaired intravascular triglyceride lipolysis constitutes a marker of clinical outcome in patients with stable angina undergoing secondary prevention treatment: a long-term follow-up study
    Andrei C Sposito
    Heart Institute InCor, Zerbini Foundation, Brasilia, Brazil
    J Am Coll Cardiol 43:2225-32. 2004

Collaborators

Detail Information

Publications82

  1. pmc Hypotheses, rationale, design, and methods for prognostic evaluation of cardiac biomarker elevation after percutaneous and surgical revascularization in the absence of manifest myocardial infarction. A comparative analysis of biomarkers and cardiac magnet
    Whady Hueb
    Heart Institute of the University of Sao Paulo, Sao Paulo, Brazil
    BMC Cardiovasc Disord 12:65. 2012
    ....
  2. doi request reprint Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial
    Pedro A Lemos
    Heart Institute InCor, University of São Paulo Medical School USP, Sao Paulo, Brazil
    EuroIntervention 8:117-9. 2012
    ..The long-term clinical performance of drug-eluting stents (DES) coated with biodegradable polymers is poorly known...
  3. ncbi request reprint Rationale and design for the PAINT randomized trial
    Pedro A Lemos
    Instituto do Coracao, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brasil
    Arq Bras Cardiol 93:547-53, 590-7. 2009
    ..We describe the rationale and design for the 'PercutAneous INTervention with biodegradable-polymer based paclitaxel-eluting or sirolimus-eluting versus bare stents for de novo coronary lesions - PAINT trial'...
  4. ncbi request reprint Randomized evaluation of two drug-eluting stents with identical metallic platform and biodegradable polymer but different agents (paclitaxel or sirolimus) compared against bare stents: 1-year results of the PAINT trial
    Pedro A Lemos
    Catheterization Laboratory, Heart Institute InCor, University of São Paulo Medical School USP, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 74:665-73. 2009
    ..The DES differed by the drug, but were identical otherwise, allowing to compare the anti-restenosis effects of sirolimus versus paclitaxel (secondary objective)...
  5. doi request reprint Early days of an ingenious aspirin and sirolimus-eluting stent
    Pedro A Lemos
    Heart Institute InCor University of Sao Paulo Medical School, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 72:195. 2008
  6. ncbi request reprint Angiographic segment size in patients referred for coronary intervention is influenced by constitutional, anatomical, and clinical features
    Pedro A Lemos
    Interventional Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Int J Cardiovasc Imaging 23:1-7. 2007
    ..We aimed to investigate in a large series of patients undergoing percutaneous intervention the relation of constitutional, anatomical, and clinical features with the reference diameter of coronary vessels treated with stenting...
  7. ncbi request reprint Delayed intravascular catabolism of chylomicron-like emulsions is an independent predictor of coronary artery disease
    Andrei C Sposito
    Heart Institute InCor, University of Sao Paulo Medical School, Hospital, Av Dr Enéas Carvalho Aguiar 44, 1o andar, 5403 900 São Paulo, Brazil
    Atherosclerosis 176:397-403. 2004
    ..In conclusion, we presently show that the rate of lipolysis and removal from the circulation of chylomicron-like emulsions constitutes an independent predictor of CAD and a marker of CAD severity...
  8. doi request reprint Dipyridamole stress and rest transmural myocardial perfusion ratio evaluation by 64 detector-row computed tomography
    Roberto C Cury
    Cardiovascular MR and CT Section, Heart Institute InCor, University of São Paulo Medical School and Heart Hospital HCOR, Sao Paulo, Brazil
    J Cardiovasc Comput Tomogr 5:443-8. 2011
    ..Myocardial stress CT perfusion (CTP) can detect myocardial ischemia...
  9. doi request reprint Additional value of dipyridamole stress myocardial perfusion by 64-row computed tomography in patients with coronary stents
    Tiago A Magalhães
    Cardiovascular MR and CT Section, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas de Carvalho Aguiar, 44 Andar AB, Cerqueira Cesar, Sao Paulo, 05403 000, Brazil
    J Cardiovasc Comput Tomogr 5:449-58. 2011
    ..However, coronary segments with prior stent implantation visualized with CTA may have limited evaluation and reduced accuracy...
  10. ncbi request reprint Impaired intravascular triglyceride lipolysis constitutes a marker of clinical outcome in patients with stable angina undergoing secondary prevention treatment: a long-term follow-up study
    Andrei C Sposito
    Heart Institute InCor, Zerbini Foundation, Brasilia, Brazil
    J Am Coll Cardiol 43:2225-32. 2004
    ..We sought to verify whether the intravascular metabolism of chylomicron-like emulsion may predict the clinical evolution of patients with coronary artery disease (CAD) undergoing secondary prevention therapy of CAD...
  11. ncbi request reprint Prognostic heterogeneity among patients with chronic stable coronary disease: determinants of long-term mortality after treatment with percutaneous intervention
    Pedro A Lemos
    Service of Interventional Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    EuroIntervention 5:239-43. 2009
    ..To evaluate the risk and predictors of death in a large population of patients with stable coronary disease treated with percutaneous intervention...
  12. ncbi request reprint Early ambulation and variability in anticoagulation during elective coronary stenting with a single intravenous bolus of low-dose, low-molecular weight heparin enoxaparin
    Silvio Zalc
    Heart Institute InCor, University of Sao Paulo Medical School, Brazil
    J Invasive Cardiol 18:45-8. 2006
    ..The primary objective of this study was to assess the feasibility of immediate sheath removal post-PCI in patients given a single low-dose intravenous (IV) bolus of enoxaparin as the sole anticoagulant...
  13. ncbi request reprint Long term follow-up of drug eluting versus bare metal stents in the treatment of saphenous vein graft lesions
    Luiz F Ybarra
    Department of Interventional Cardiology, Heart Institute InCor, University of Sao Paulo, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 82:E856-63. 2013
    ..The aim of this study was to address the late outcome of DES versus BMS for the treatment of SVG lesions...
  14. ncbi request reprint Stenting vs. balloon angioplasty with provisional stenting for the treatment of vessels with small reference diameter
    Pedro A Lemos
    Catheterization Laboratory, Heart Institute InCor of University of São Paulo Medical School, Sao Paulo, Brazil
    Catheter Cardiovasc Interv 55:309-14. 2002
    ..Treatment of small vessels with balloon dilatation and provisional stenting or with primary stenting yielded similar late outcomes. Operators' choice of treatment strategy was based on particular angiographic characteristics...
  15. ncbi request reprint Luminal recovery from six to twelve months after implantation of "thicker strut" coronary stents
    George C X Meireles
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Cardiol 93:210-3. 2004
    ..At multivariate analysis, lumen loss at 6 months (p = 0.018) and deployment pressure (p = 0.041) independently predicted the changes in MLD between 6 and 12 months...
  16. pmc TCF7L2 polymorphism rs7903146 is associated with coronary artery disease severity and mortality
    André Gustavo P Sousa
    Laboratory of Genetics and Molecular Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    PLoS ONE 4:e7697. 2009
    ..This study aimed to evaluate the association between TCF7L2 polymorphism rs7903146 and coronary artery disease in diabetic and non-diabetic subjects...
  17. doi request reprint Evaluation of plaque composition by intravascular ultrasound "virtual histology": the impact of dense calcium on the measurement of necrotic tissue
    Fernando J R Sales
    Heart Institute, University of Sao Paulo Medical School, Brazil
    EuroIntervention 6:394-9. 2010
    ..We aimed to evaluate if the co-localisation of calcium and necrosis in intravascular ultrasound virtual histology (IVUS-VH) is due to artefact, and whether this effect can be mathematically estimated...
  18. ncbi request reprint [Coronary calcium score as predictor of stenosis and events in pretransplant renal chronic failure]
    Miguel Abraão Rosário
    Instituto do Coracao, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    Arq Bras Cardiol 94:236-43, 252-60, 239-47. 2010
    ..CT Scan evaluation of Coronary Calcium Score (CCS) has proven to be of prognostic value for the population reporting no renal condition...
  19. ncbi request reprint The pre-existence of an acute coronary event predicts differences in biological parameters and clinical evolution among patients with longstanding stable angina
    Andrei C Sposito
    Heart Institute InCor, University of São Paulo Medicine School, Sao Paulo, Brazil
    Int J Cardiol 91:193-200. 2003
    ..In the current study, we investigated whether differences might exist in the clinical, angiographic and biological parameters between these two distinct clinical presentations...
  20. ncbi request reprint Coronary revascularization (surgical or percutaneous) decreases mortality after the first year in diabetic subjects but not in nondiabetic subjects with multivessel disease: an analysis from the Medicine, Angioplasty, or Surgery Study (MASS II)
    Paulo R Soares
    Heart Institute, University of Sao Paulo Medical School, Av Dr Eneas de Carvalho Aguiar, 44 sala 114, São Paulo SP 05403 000, Brazil
    Circulation 114:I420-4. 2006
    ..It is currently unknown whether revascularization procedures are associated with an improvement in mortality among diabetic subjects, as compared with a more conservative medical treatment...
  21. ncbi request reprint First-in-man randomised comparison of a novel sirolimus-eluting stent with abluminal biodegradable polymer and thin-strut cobalt-chromium alloy: INSPIRON-I trial
    Expedito E Ribeiro
    Department of Interventional Cardiology, Heart Institute InCor, University of Sao Paulo, Sao Paulo, Brazil
    EuroIntervention 9:1380-4. 2014
    ..001). At two-year follow-up, incidence of MACE was similar between groups (7.9 vs. 21.1%, respectively; p=0.20), with lower target lesion revascularisation for Inspiron (0 vs. 21.1%, respectively; p=0.01) and no stent thrombosis...
  22. ncbi request reprint Comparison of late luminal loss response pattern after sirolimus-eluting stent implantation or conventional stenting
    Pedro A Lemos
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Circulation 110:3199-205. 2004
    ..We investigated the pattern of late luminal loss after sirolimus-eluting or bare stent implantation...
  23. pmc The role of invasive therapies in elderly patients with acute myocardial infarction
    Jose C Nicolau
    Acute Coronary Disease Unit, Faculdade de Medicina, Heart Institute, Hospital das Clinicas, Universidade de Sao Paulo, Sao Paulo, Brazil
    Clinics (Sao Paulo) 64:553-60. 2009
    ....
  24. ncbi request reprint Impact of baseline renal function on mortality after percutaneous coronary intervention with sirolimus-eluting stents or bare metal stents
    Pedro A Lemos
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Cardiol 95:167-72. 2005
    ..It seems unlikely that restenosis could be a contributing factor that influenced the increased mortality of patients who had impaired renal function...
  25. ncbi request reprint Dipyridamole stress and rest myocardial perfusion by 64-detector row computed tomography in patients with suspected coronary artery disease
    Roberto C Cury
    Cardiovascular MR and CT Section, University of São Paulo Medical, School, Sao Paulo, Brazil
    Am J Cardiol 106:310-5. 2010
    ..The anatomical-perfusion information provided by this combined CT protocol may allow identification of false-positive results by SPECT...
  26. doi request reprint Emerging technologies: polymer-free phospholipid encapsulated sirolimus nanocarriers for the controlled release of drug from a stent-plus-balloon or a stand-alone balloon catheter
    Pedro A Lemos
    Department of Interventional Cardiology, University of Sao Paulo Medical School, Sao Paulo, Brazil
    EuroIntervention 9:148-56. 2013
    ....
  27. ncbi request reprint [Intracoronary inflammatory markers after percutaneous coronary interventions]
    Wilson Salgado Filho
    Instituto do Coracao, Hospital das Clinicas, FMUSP, Sao Paulo, SP
    Arq Bras Cardiol 85:180-5. 2005
    ..To analyze intracoronary release of inflammatory markers (IM) after percutaneous coronary interventions (PCI) and compare their concentrations concerning the type of PCI used (rotablator vs. balloon angioplasty)...
  28. pmc MYLIP p.N342S polymorphism is not associated with lipid profile in the Brazilian population
    Paulo C J L Santos
    Laboratory of Genetics and Molecular Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Lipids Health Dis 11:83. 2012
    ..In this scenario, and because of a possible pharmacotherapeutic target of dyslipidemia, the main aim of this study was to assess the influence of the MYLIP p.N342S polymorphism on lipid profile in Brazilian individuals...
  29. pmc LPA rs10455872 polymorphism is associated with coronary lesions in Brazilian patients submitted to coronary angiography
    Paulo Cjl Santos
    Laboratory of Genetics and Molecular Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Av, Dr, Enéas de Carvalho Aguiar, 44 Cerqueira cesar, Sao Paulo, SP CEP 05403 000, Brazil
    Lipids Health Dis 13:74. 2014
    ..In this scenario, the main aim of this study was to assess the influence of the LPA polymorphisms on coronary lesions in Brazilian patients...
  30. doi request reprint The Supralimus sirolimus-eluting stent
    Pedro A Lemos
    Department of Interventional Cardiology, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Expert Rev Med Devices 10:295-300. 2013
    ....
  31. ncbi request reprint Angiotensinogen M235T polymorphism is associated with coronary artery disease severity
    Jose R Lanz
    Laboratory of Genetics and Molecular Cardiology and Hemodynamics Laboratory, Heart Institute InCor, University of Sao Paulo Medical School, Brazil
    Clin Chim Acta 362:176-81. 2005
    ..The aim of the present study is to determine if there is an association between the M235T variant of the angiotensinogen gene and severity of coronary artery disease in patients with clinically suspected disease undergoing cineangiogram...
  32. ncbi request reprint Value of rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography for detection of coronary artery disease
    Wilson Mathias
    Echocardiographic Laboratory, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Am Coll Cardiol 41:1583-9. 2003
    ..We studied the value of a rapid beta-blocker injection at peak dobutamine-atropine stress echocardiography (DASE) for the detection of coronary artery disease (CAD)...
  33. ncbi request reprint An unusual case of angina pectoris: a patient with isolated non-compaction of the left ventricular myocardium
    André L Dabarian
    Cardiomyopathy Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Eur J Echocardiogr 9:728-30. 2008
    ..It is a possible mechanism for progressive myocardial dysfunction seen in these patients...
  34. ncbi request reprint Noninvasive assessment of coronary plaque burden using multislice computed tomography
    Nico R Mollet
    Department of Cardiology, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 95:1165-9. 2005
    ..Overall, 65% of plaques were calcified, 24% were noncalcified, and 11% were mixed. Plaques were predominantly located in the proximal and middle segments of the main coronary vessels...
  35. ncbi request reprint To heal without renarrowing: is it possible to make it real?
    Pedro A Lemos
    Catheter Cardiovasc Interv 70:661. 2007
  36. ncbi request reprint Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation
    Sjoerd H Hofma
    Department of Cardiology, Thoraxcenter, Erasmus MC, Bd 412, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Heart J 27:166-70. 2006
    ..We assessed local epicardial endothelial function 6 months after sirolimus-eluting stent (SES) or bare metal stent (BS) implantation...
  37. ncbi request reprint Sirolimus-eluting stents remain superior to bare-metal stents at two years: medium-term results from the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry
    Andrew T L Ong
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    J Am Coll Cardiol 47:1356-60. 2006
    ..The purpose of this study was to investigate the medium-term (two year) outcome of the unrestricted utilization of sirolimus-eluting stents (SES) in an all-comer population...
  38. ncbi request reprint Risk factors for impaired health status differ in women and men treated with percutaneous coronary intervention in the drug-eluting stent era
    Susanne S Pedersen
    Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Psychosom Res 61:11-7. 2006
    ....
  39. ncbi request reprint Multi-lesion culotte and crush bifurcation stenting with sirolimus-eluting stents: long-term angiographic outcome
    Joost Daemen
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam
    J Invasive Cardiol 15:653-6. 2003
  40. ncbi request reprint Elective sirolimus-eluting stent implantation for left main coronary artery disease: six-month angiographic follow-up and 1-year clinical outcome
    Chourmouzios A Arampatzis
    Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 62:292-6; discussion 297. 2004
    ..04 +/- 0.65 mm and one focal restenosis (8% of patients). Elective SES implantation for LM disease was associated with zero mortality and a very low incidence of additional major adverse events at 1 year...
  41. ncbi request reprint Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions
    Maniyal Vijayakumar
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    J Invasive Cardiol 17:10-2. 2005
    ..Various stent designs have failed to show significant improvement in target lesion revascularization (TLR) rates. The present study evaluates the clinical outcomes following sirolimus-eluting stent implantation for ostial lesions...
  42. ncbi request reprint Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography
    Koen Nieman
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Circulation 106:2051-4. 2002
    ....
  43. ncbi request reprint Significant reduction in restenosis after the use of sirolimus-eluting stents in the treatment of chronic total occlusions
    Angela Hoye
    Department of Interventional Cardiology, Erasmus MC, Rotterdam, The Netherlands
    J Am Coll Cardiol 43:1954-8. 2004
    ..The aim of this study was to assess sirolimus-eluting stent (SES) implantation for the treatment of chronic total coronary occlusions (CTO)...
  44. ncbi request reprint Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Circulation 109:2500-2. 2004
    ..We evaluated the clinical and angiographic outcomes of patients presenting with restenosis after sirolimus-eluting stent (SES) implantation treated with repeated percutaneous intervention...
  45. ncbi request reprint Incidence of thrombotic stent occlusion during the first three months after sirolimus-eluting stent implantation in 500 consecutive patients
    Evelyn Regar
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Am J Cardiol 93:1271-5. 2004
    ..These cases occurred in diabetic women with complex coronary lesions. Intravascular ultrasound examination showed inadequate stent expansion and uncovered distal dissection as possible mechanical explanations for the thrombosis...
  46. ncbi request reprint Effectiveness of the sirolimus-eluting stent in the treatment of patients with a prior history of coronary artery bypass graft surgery
    Angela Hoye
    Department of Cardiology, Thoraxcenter, Erasmus Medical Centre, Rotterdam, The Netherlands
    Coron Artery Dis 15:171-5. 2004
    ..We evaluated the impact of utilizing the sirolimus-eluting stent (SES) in this high-risk population...
  47. ncbi request reprint Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study
    Francesco Saia
    Erasmus MC, Thoraxcenter, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 61:455-60. 2004
    ..13 +/- 0.34 and restenosis rate was 7.7%. Although not routinely recommended in every patient, SES postdilatation with largely oversized balloons appears a safe and effective strategy for selected patients...
  48. ncbi request reprint Very long sirolimus-eluting stent implantation for de novo coronary lesions
    Muzaffer Degertekin
    Department of Interventional Cardiology, Thoraxcentre, Erasmus MC, Rotterdam, The Netherlands
    Am J Cardiol 93:826-9. 2004
    ..1%), and the overall incidence of major cardiac events was 8.3%. Thus, SES implantation appears safe and effective for de novo coronary lesions requiring multiple stent placement over a very long vessel segment...
  49. ncbi request reprint Treatment of very small vessels with 2.25-mm diameter sirolimus-eluting stents (from the RESEARCH registry)
    Pedro A Lemos
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Am J Cardiol 93:633-6. 2004
    ..7% versus 3.9%, respectively (p = 0.1). The 12-month target lesion revascularization rate was 5.5%. In conclusion, 2.25-mm SESs were associated with low rates of clinical and angiographic late complications...
  50. ncbi request reprint Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Circulation 109:1366-70. 2004
    ..The factors associated with the occurrence of restenosis after sirolimus-eluting stent (SES) implantation in complex cases are currently unknown...
  51. ncbi request reprint Effectiveness of sirolimus-eluting stent for treatment of left main coronary artery disease
    Chourmouzios A Arampatzis
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 92:327-9. 2003
    ..The implantation of this stent was associated with abolition of post-discharge fatal events and percutaneous reintervention...
  52. ncbi request reprint Intravascular ultrasound evaluation after sirolimus eluting stent implantation for de novo and in-stent restenosis lesions
    Muzaffer Degertekin
    Department of Cardiology, Erasmus Medical Center, Thoraxcenter, Bd 48, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Heart J 25:32-8. 2004
    ..The aim of this study is to compare the efficacy of sirolimus-eluting stents (SES) on neointimal growth and vessel remodelling for in-stent restenosis versus de novo coronary artery lesions using serial intravascular ultrasound (IVUS)...
  53. ncbi request reprint Sirolimus-eluting stent implantation in ST-elevation acute myocardial infarction: a clinical and angiographic study
    Francesco Saia
    Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Circulation 108:1927-9. 2003
    ..Sirolimus-eluting stents (SES) have recently been proven to reduce restenosis and reintervention compared with bare stents. Safety and effectiveness of SES in acute myocardial infarction remain unknown...
  54. ncbi request reprint Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Bd 406, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Circulation 108:257-60. 2003
    ..We describe the clinical and morphological patterns of restenosis after sirolimus-eluting stent (SES) implantation...
  55. ncbi request reprint Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry
    Pedro A Lemos
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Dr Molewaterplein 40, NL 3015 GD Rotterdam, The Netherlands
    J Am Coll Cardiol 41:2093-9. 2003
    ..This study evaluated the early outcomes of patients with acute coronary syndromes (ACS) treated with sirolimus-eluting stents (SES)...
  56. ncbi request reprint Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris
    Nico R Mollet
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, Netherlands
    J Am Coll Cardiol 43:2265-70. 2004
    ....
  57. ncbi request reprint Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter
    Angela Hoye
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 94:112-4. 2004
    ..At a mean follow-up of 399 +/- 120 days, the survival-free of major adverse events was 95%, with no patient requiring target lesion revascularization...
  58. ncbi request reprint The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease
    Ron T van Domburg
    Thoraxcenter, room H 539, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Heart J 26:675-81. 2005
    ..Therefore, we investigated the impact of SES on the clinical practice of CABG and PCI in a series of unselected consecutive patients...
  59. ncbi request reprint Elective sirolimus-eluting stent implantation for multivessel disease involving significant LAD stenosis: one-year clinical outcomes of 99 consecutive patients--the Rotterdam experience
    Chourmouzios A Arampatzis
    Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 63:57-60. 2004
    ..6%. SES implantation for multivessel disease in a consecutive series of patients is associated with low incidence of adverse events. The reported results are related predominantly to the reduction in repeat revascularization...
  60. ncbi request reprint Predictors of survival after contemporary percutaneous coronary revascularization for acute myocardial infarction in the real world
    Chi Hang Lee
    Cardiac Department, National University Hospital, Level 3, Main Building 5, Lower Kent Ridge Road, Singapore, 119074
    J Invasive Cardiol 16:627-31. 2004
    ..Among patients with cardiogenic shock, similar mortality was observed in patients with anterior myocardial infarction (MI) or inferior MI with/without right ventricle involvement...
  61. ncbi request reprint Effectiveness of sirolimus-eluting stent implantation for the treatment of coronary artery disease in octogenarians
    Maniyal Vijayakumar
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 94:909-13. 2004
    ..SES implantation in octogenarians appears to be feasible and is associated with very small subsequent need for repeat target vessel revascularization at 1 year...
  62. ncbi request reprint Type D personality predicts death or myocardial infarction after bare metal stent or sirolimus-eluting stent implantation: a Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry substudy
    Susanne S Pedersen
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    J Am Coll Cardiol 44:997-1001. 2004
    ..Type D patients experience increased negative emotions and tend not to express these emotions in social interactions...
  63. ncbi request reprint Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings
    Kengo Tanabe
    Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 94:115-8. 2004
    ..At 6 months, the incidence of major adverse cardiac events was 10.3% (1 death and 5 target lesion revascularizations) with no episodes of acute myocardial infarction or stent thrombosis...
  64. ncbi request reprint Effectiveness of the sirolimus-eluting stent in the treatment of saphenous vein graft disease
    Angela Hoye
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    J Invasive Cardiol 16:230-3. 2004
    ..Increased utilization of distal protection devices might reduce the peri-procedural rate of AMI...
  65. ncbi request reprint Standard versus user-interactive assessment of significant coronary stenoses with multislice computed tomography coronary angiography
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 94:1590-3. 2004
    ..Sensitivity and specificity were 58% and 96% and 96% and 97%, for standard projections and interactive postprocessing protocol, respectively...
  66. ncbi request reprint Fluvastatin reduces the 4-year cardiac risk in patients with multivessel disease
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, Netherlands
    Int J Cardiol 98:479-86. 2005
    ..To evaluate the impact of the extent of coronary disease (single- or multivessel) and of fluvastatin treatment on the incidence of long-term cardiac atherosclerotic complications in the Lescol Intervention Prevention Study (LIPS)...
  67. ncbi request reprint Effect of fluvastatin on long-term outcome after coronary revascularization with stent implantation
    Francesco Saia
    Erasmus MC, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 93:92-5. 2004
    ..4, p = 0.03)...
  68. ncbi request reprint Long-term fluvastatin reduces the hazardous effect of renal impairment on four-year atherosclerotic outcomes (a LIPS substudy)
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 95:445-51. 2005
    ..The benefit of fluvastatin was unrelated to any effect on renal function...
  69. ncbi request reprint Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy
    Francesco Saia
    Erasmus MC, Thoraxcenter, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Am J Cardiol 92:200-3. 2003
  70. ncbi request reprint Clinical features and outcomes of primary percutaneous coronary intervention for subacute stent thrombosis--a case series
    Chi Hang Lee
    Int J Cardiol 98:171-2. 2005
  71. ncbi request reprint Higher intracoronary attenuation improves diagnostic accuracy in MDCT coronary angiography
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Dr Molewaterplein 40, Rotterdam, The Netherlands
    AJR Am J Roentgenol 187:W430-3. 2006
    ..The purpose of this study was to investigate whether the amount of intracoronary attenuation influences the diagnostic accuracy of MDCT coronary angiography in the detection of clinically significant stenosis...
  72. ncbi request reprint Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the "real world": the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Circulation 109:190-5. 2004
    ..The effectiveness of sirolimus-eluting stents in unselected patients treated in the daily practice is currently unknown...
  73. ncbi request reprint Stent fracture and restenosis in the drug-eluting stent era
    Georgios Sianos
    Department of Interventional Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 61:111-6. 2004
  74. ncbi request reprint Cost-effectiveness of the unrestricted use of sirolimus-eluting stents vs. bare metal stents at 1 and 2-year follow-up: results from the RESEARCH Registry
    Andrew T L Ong
    Thoraxcenter, Erasmus Medical Center, Ba 583, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Heart J 27:2996-3003. 2006
    ....
  75. ncbi request reprint Short- and long-term clinical benefit of sirolimus-eluting stents compared to conventional bare stents for patients with acute myocardial infarction
    Pedro A Lemos
    Erasmus Medical Center, Thoraxcenter, Rotterdam, Netherlands
    J Am Coll Cardiol 43:704-8. 2004
    ..This study investigated the clinical outcomes of patients with ST-segment elevation myocardial infarction (MI) treated with sirolimus-eluting stents (SESs) or with conventional bare stents...
  76. ncbi request reprint Drug-eluting stents show delayed healing: paclitaxel more pronounced than sirolimus
    Heleen M M van Beusekom
    Department of Cardiology, Ee 2355b, Erasmus Medical Center Rotterdam, Dr Molewaterplein 50, PO Box 1738, 3000 Rotterdam, The Netherlands
    Eur Heart J 28:974-9. 2007
    ....
  77. ncbi request reprint One-year outcomes of coronary artery bypass graft surgery versus percutaneous coronary intervention with multiple stenting for multisystem disease: a meta-analysis of individual patient data from randomized clinical trials
    Nestor Mercado
    Department of Interventional Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
    J Thorac Cardiovasc Surg 130:512-9. 2005
    ....
  78. ncbi request reprint Polymeric stents: degradable but strong
    Pedro A Lemos
    Catheter Cardiovasc Interv 70:524. 2007
  79. ncbi request reprint No change in endothelial-dependent vasomotion late after coronary irradiation
    Sjoerd H Hofma
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Cardiovasc Radiat Med 5:156-61. 2004
    ..This study was conducted to assess endothelial function late after the irradiation of atherosclerotic coronary arteries...
  80. ncbi request reprint Successful use of a new guidewire with radiofrequency ablation capability for the treatment of chronic total occlusion at the ostium of the left anterior descending artery
    Angela Hoye
    Department of Interventional Cardiology, Erasmus MC Rotterdam, Thoraxcentre Bd 404, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    J Invasive Cardiol 17:277-9. 2005
  81. ncbi request reprint Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis
    Francesco Saia
    Thoraxcenter, Erasmus University Medical Center, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 62:283-8. 2004
    ..1% VBT vs. 81.5% SES; P = 0.8 by log rank). The result of this nonrandomized study suggests that sirolimus-eluting stent implantation is at least as effective as vascular brachytherapy in the treatment of in-stent restenosis...
  82. ncbi request reprint Drug-eluting stents in the treatment of atherosclerotic coronary heart disease
    Pedro A Lemos
    Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam
    Indian Heart J 54:212-6. 2002