Katia Ramos M Leite

Summary

Country: Brazil

Publications

  1. pmc The role of micro RNAs let7c, 100 and 218 expression and their target RAS, C-MYC, BUB1, RB, SMARCA5, LAMB3 and Ki-67 in prostate cancer
    Sabrina T Reis
    Faculdade de Medicina da Universidade de Sao Paulo, Urology Department, Laboratory of Medical Research, LIM55, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 68:652-7. 2013
  2. pmc Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model
    Fábio T Watanabe
    Universidade de Sao Paulo, Laboratory of Medical Investigation, Department of Urology Lim55, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 66:2121-4. 2011
  3. pmc miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer
    Sabrina Thalita Reis
    Laboratory of Medical Investigation LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    BMC Urol 12:14. 2012
  4. pmc MicroRNA 100: a context dependent miRNA in prostate cancer
    Katia R M Leite
    Faculdade de Medicina da Universidade de Sao Paulo, Laboratory of Medical Research, Department of Urology, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 68:797-802. 2013
  5. doi request reprint MicroRNA expression profiles in the progression of prostate cancer--from high-grade prostate intraepithelial neoplasia to metastasis
    Katia R M Leite
    Laboratory of Medical Investigation, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 31:796-801. 2013
  6. pmc Immunomodulatory effects of recombinant BCG expressing pertussis toxin on TNF-alpha and IL-10 in a bladder cancer model
    Daher C Chade
    Division of Urology, Laboratory of Medical Investigation University of São Paulo, Sao Paulo, Brazil
    J Exp Clin Cancer Res 27:78. 2008
  7. ncbi request reprint Monoclonality of asynchronous bilateral lymphoma of the testis
    K R Leite
    Laboratory of Molecular and Surgical Pathology, Sirio Libanes Hospital, Sao Paulo, Brazil
    Eur Urol 38:774-7. 2000
  8. doi request reprint Change in expression of miR-let7c, miR-100, and miR-218 from high grade localized prostate cancer to metastasis
    Katia R M Leite
    Laboratory of Medical Investigation, LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 29:265-9. 2011
  9. doi request reprint miRNA analysis of prostate cancer by quantitative real time PCR: comparison between formalin-fixed paraffin embedded and fresh-frozen tissue
    Katia R M Leite
    Laboratory of Medical Investigation LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 29:533-7. 2011
  10. ncbi request reprint Effects of curcumin in an orthotopic murine bladder tumor model
    Katia R M Leite
    Laboratory of Medical Investigation, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Int Braz J Urol 35:599-606; discussion 606-7. 2009

Collaborators

Detail Information

Publications27

  1. pmc The role of micro RNAs let7c, 100 and 218 expression and their target RAS, C-MYC, BUB1, RB, SMARCA5, LAMB3 and Ki-67 in prostate cancer
    Sabrina T Reis
    Faculdade de Medicina da Universidade de Sao Paulo, Urology Department, Laboratory of Medical Research, LIM55, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 68:652-7. 2013
    ....
  2. pmc Curcumin, but not Prima-1, decreased tumor cell proliferation in the syngeneic murine orthotopic bladder tumor model
    Fábio T Watanabe
    Universidade de Sao Paulo, Laboratory of Medical Investigation, Department of Urology Lim55, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 66:2121-4. 2011
    ..Prima-1 is a compound that induces apoptosis in human tumor cells, restoring the function of mutant p53. Our study aimed to evaluate the effects of curcumin and prima-1 in an animal model of bladder cancer...
  3. pmc miR-21 may acts as an oncomir by targeting RECK, a matrix metalloproteinase regulator, in prostate cancer
    Sabrina Thalita Reis
    Laboratory of Medical Investigation LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    BMC Urol 12:14. 2012
    ..Our aim is to investigate the levels of expression of RECK and miR-21 in PCa comparing with classical prognostic factors and disease outcome and also test if RECK is a target of miR-21 in in vitro study using PCa cell line...
  4. pmc MicroRNA 100: a context dependent miRNA in prostate cancer
    Katia R M Leite
    Faculdade de Medicina da Universidade de Sao Paulo, Laboratory of Medical Research, Department of Urology, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 68:797-802. 2013
    ..This suggests that miR-100 may be a context-dependent miRNA, acting as oncogene or tumor suppressor miRNA. Our aim is to demonstrate the role of miR-100 in the control of predicted target genes in prostate cancer cell lines...
  5. doi request reprint MicroRNA expression profiles in the progression of prostate cancer--from high-grade prostate intraepithelial neoplasia to metastasis
    Katia R M Leite
    Laboratory of Medical Investigation, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 31:796-801. 2013
    ..The aim of this study is to propose a new model including a possible role for recently described micro RNAs in prostate cancer (CaP) progression...
  6. pmc Immunomodulatory effects of recombinant BCG expressing pertussis toxin on TNF-alpha and IL-10 in a bladder cancer model
    Daher C Chade
    Division of Urology, Laboratory of Medical Investigation University of São Paulo, Sao Paulo, Brazil
    J Exp Clin Cancer Res 27:78. 2008
    ..This preclinical study was designed to compare the modulatory effects of BCG and rBCG-S1PT on bladder TNF-alpha and IL-10 expression and to evaluate antitumour activity...
  7. ncbi request reprint Monoclonality of asynchronous bilateral lymphoma of the testis
    K R Leite
    Laboratory of Molecular and Surgical Pathology, Sirio Libanes Hospital, Sao Paulo, Brazil
    Eur Urol 38:774-7. 2000
    ..The question is raised whether either the patient has a predisposition to present new clones of transformed lymphocytes, or the same disease using the same pathway from a systemic reservoir infiltrates the contralateral testis...
  8. doi request reprint Change in expression of miR-let7c, miR-100, and miR-218 from high grade localized prostate cancer to metastasis
    Katia R M Leite
    Laboratory of Medical Investigation, LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 29:265-9. 2011
    ..The aim of this study is to find miRNAs involved in prostate cancer progression comparing the profile of miRNA expressed by localized high grade carcinoma and bone metastasis...
  9. doi request reprint miRNA analysis of prostate cancer by quantitative real time PCR: comparison between formalin-fixed paraffin embedded and fresh-frozen tissue
    Katia R M Leite
    Laboratory of Medical Investigation LIM55, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Urol Oncol 29:533-7. 2011
    ..Our aim is to compare miRNA profiles from formalin-fixed paraffin embedded (FFPE) tissues with fresh-frozen prostate cancer tissues...
  10. ncbi request reprint Effects of curcumin in an orthotopic murine bladder tumor model
    Katia R M Leite
    Laboratory of Medical Investigation, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Int Braz J Urol 35:599-606; discussion 606-7. 2009
    ..The results of our study suggest that further research is warranted to confirm our findings...
  11. ncbi request reprint The use of immunohistochemistry for diagnosis of prostate cancer
    Katia R M Leite
    Laboratory of Medical Investigation, Division of Urology, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Int Braz J Urol 36:583-90. 2010
    ..There has been no reported study that has reviewed characteristics of radical prostatectomies (RPs) when immunohistochemistry (IHC) was necessary for definitive diagnosis...
  12. doi request reprint MicroRNA-100 expression is independently related to biochemical recurrence of prostate cancer
    Katia R M Leite
    Laboratory of Medical Investigation, Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Urol 185:1118-22. 2011
    ..Abnormal miRNA expression has emerged as crucial factors in carcinogenesis and is important in the comprehension of prostate cancer behavior. We determined the correlation of miRNA expression profiles with prostate cancer progression...
  13. doi request reprint Cdx2, cytokeratin 20, thyroid transcription factor 1, and prostate-specific antigen expression in unusual subtypes of prostate cancer
    Katia Ramos Moreira Leite
    Laboratory of Surgical and Molecular Pathology, Hospital Sirio Libanes, São Paulo 01308 050, Brazil
    Ann Diagn Pathol 12:260-6. 2008
    ..Pathologist should be alert when evaluating immunohistochemical profiles of unusual histologic findings of prostate cancer, mostly in distant sites...
  14. ncbi request reprint Histopathological findings in extended prostate biopsy with PSA < or = 4 ng/mL
    Katia R Leite
    Laboratory of Medical Investigation LIM55 University of Sao Paulo, USP, SP, Brazil
    Int Braz J Urol 34:283-90; discussion 290-2. 2008
    ..This study describes the incidence of malignancy and tumor characteristics in extended prostate biopsies with PSA <or= 4 ng/mL...
  15. ncbi request reprint Abnormal expression of MDM2 in prostate carcinoma
    K R Leite
    Laboratory of Surgical and Molecular Pathology, Hospital Sirio Libanes, Sao Paulo, Brazil
    Mod Pathol 14:428-36. 2001
    ..Finally, we propose that the MDM2-positive/p53-positive phenotype identifies prostate cancers with aggressive behavior...
  16. ncbi request reprint Solitary fibrous tumor in bladder wall
    Katia R M Leite
    Laboratory of Surgical and Molecular Pathology, Syrian Lebanese Hospital, Discipline of Urology, Paulista School of Medicine, Federal University of Sao Paulo UNIFESP, Sao Paulo, SP, Brazil
    Int Braz J Urol 30:406-9. 2004
    ..We report the seventh case of solitary fibrous tumor in bladder wall, discussing differential diagnoses, and call the attention to this rarely occurring entity, which has benign behavior and should be managed conservatively...
  17. ncbi request reprint Primary lymphoma of the bladder
    Katia R M Leite
    Laboratory of Surgical and Molecular Pathology, Syrian Lebanese Hospital, Sao Paulo, SP, Brazil
    Int Braz J Urol 30:37-9. 2004
    ..The authors emphasize the differential diagnosis due to the great differences concerning prognosis and therapeutic approach...
  18. ncbi request reprint Repeat prostate biopsies following diagnoses of prostate intraepithelial neoplasia and atypical small gland proliferation
    Katia R Leite
    Laboratory of Surgical and Molecular Pathology, Syrian Lebanese Hospital, Sao Paulo, SP, Brazil
    Int Braz J Urol 31:131-6. 2005
    ..To assess the indexes and findings on repeat biopsies...
  19. ncbi request reprint Helicobacter pylori and cagA gene detected by polymerase chain reaction in gastric biopsies: correlation with histological findings, proliferation and apoptosis
    Katia Ramos Moreira Leite
    Surgical and Molecular Pathology Laboratory, Hospital Sirio Libanes, Sao Paulo, Brazil
    Sao Paulo Med J 123:113-8. 2005
    ..Our objective was to detect HP and the cagA gene (cagPAI marker) by polymerase chain reaction (PCR) and to correlate these results to histological findings, epithelial cell proliferation and apoptosis...
  20. ncbi request reprint [Well differentiated localized prostate carcinoma: prognostic relevance of tertiary Gleason pattern 4 and tumor volume]
    Katia R M Leite
    Laboratório de Patologia Cirúrgica e Molecular, Hospital Sirio Libanes, SP
    Rev Assoc Med Bras 51:329-33. 2005
    ..The purpose of this study was to evaluate the importance of presence and percentage of a Gleason pattern 4 and of tumor volume in the outcome of patients treated for well-differentiated prostate adenocarcinoma...
  21. ncbi request reprint Paratesticular rhabdomyoma
    Katia Ramos Moreira Leite
    Laboratório de Patologia Cirúrgica e Molecular, Hospital Sirio Libanes, Sao Paulo, Brazil 01308 050
    Ann Diagn Pathol 10:239-40. 2006
    ..An inguinal resection was performed, and the patient is well with no local recurrence or metastasis 13 months after surgery...
  22. ncbi request reprint Benign glandular inclusion in obturator lymph node of a man treated for prostate carcinoma
    Katia Ramos Moreira Leite
    Laboratory of Surgical and Molecular Pathology, Syrian Lebanese Hospital, University of Sao Paulo Medical School, Sao Paolo, Brazil
    Pathol Int 57:454-7. 2007
    ..Pathologists should be aware of benign glandular inclusion in obturator lymph nodes dissected during a radical prostatectomy for treatment of prostate cancer in order to avoid the incorrect diagnosis of metastatic disease...
  23. pmc Prostate cancer detection at rebiopsy after an initial benign diagnosis: results using sextant extended prostate biopsy
    Katia Ramos Moreira Leite
    Laboratório de Investigação Médica da Disciplina de Urologia, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 63:339-42. 2008
    ..It is well known that after a diagnosis of small acinar proliferation (ASAP) or high grade prostate intraepithelial neoplasia (HGPIN), the possibility of finding cancer is approximately 40% and 30%, respectively...
  24. pmc Increased expression of MMP-9 and IL-8 are correlated with poor prognosis of Bladder Cancer
    Sabrina Thalita Reis
    Urology Department, University of Sao Paulo Medical School, Sao Paulo, Brazil
    BMC Urol 12:18. 2012
    ..The purpose of this study was to investigate whether the expression of MMP-9, MMP-2 and its specific inhibitors, are expressed in a reproducible, specific pattern and if the profiles are related to prognosis in Bladder Cancer (BC)...
  25. ncbi request reprint Discrimination of prostate carcinoma from benign prostate tissue fragments in vitro by estimating the gross biochemical alterations through Raman spectroscopy
    Landulfo Silveira
    Biomedical Engineering Institute, Universidade Camilo Castelo Branco UNICASTELO, Parque Tecnológico de São José dos Campos, Estr Dr Altino Bondesan, 500, Eugênio de Melo, Sao Jose dos Campos, SP, 12247 016, Brazil
    Lasers Med Sci 29:1469-77. 2014
    ..Raman spectroscopy is an analytical technique with possibility for identifying biochemical constitution of prostate and could be used for diagnostic purposes. ..
  26. ncbi request reprint Cystectomy with orthotopic reconstruction following radical retropubic prostatectomy
    Ari Miotto
    Division of Urology, Paulista School of Medicine, Federal University of Sao Paulo, UNIFESP, Syrian Lebanese Hospital, Sao Paulo, SP, Brazil
    Int Braz J Urol 30:125-7. 2004
    ..Nevertheless, despite possible technical difficulties found during surgery, the orthotopic urinary shunt is a reasonable option in selected cases...
  27. ncbi request reprint Value of various PSA parameters for diagnosing prostate cancer in men with normal digital rectal examination
    Ari Miotto
    Division of Urology, Paulista School of Medicine, Federal University of Sao Paulo, UNIFESP, Syrian Lebanese Hospital, Sao Paulo, SP, Brazil
    Int Braz J Urol 30:109-13. 2004
    ..The objective in this work was to define the incidence of disease in a population of men with abnormal values of PSA variables and normal digital rectal examination...