Holzhausen M, Cortelli J, da Silva V, Franco G, Cortelli S, Vergnolle N. Protease-activated receptor-2 (PAR(2)) in human periodontitis. J Dent Res. 2010;89:948-53 pubmed publisher
..We conclude that PAR(2) mRNA expression and its potential activators are elevated in human chronic periodontitis, therefore suggesting that PAR(2) may play a role in periodontal inflammation. ..
Holzhausen M, Balejo R, Lara G, Cortelli S, Saad W, Cortelli J. Nafamostat mesilate, a potent tryptase inhibitor, modulates periodontitis in rats. Clin Oral Investig. 2011;15:967-73 pubmed publisher
..05). These data provided evidence that tryptase inhibition with NM attenuates gingival granulocyte infiltration and ABL in an experimental model of periodontitis in rats...