Renata Gorjao

Summary

Country: Brazil

Publications

  1. ncbi request reprint Regulation of interleukin-2 signaling by fatty acids in human lymphocytes
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil
    J Lipid Res 48:2009-19. 2007
  2. ncbi request reprint Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte function
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Av Prof Lineu Prestes, 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
    Clin Nutr 25:923-38. 2006
  3. ncbi request reprint Regulation of human lymphocyte proliferation by fatty acids
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Cell Biochem Funct 25:305-15. 2007
  4. doi request reprint Comparative effects of DHA and EPA on cell function
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Pharmacol Ther 122:56-64. 2009
  5. ncbi request reprint Effects of EPA and DHA on proliferation, cytokine production, and gene expression in Raji cells
    Rozangela Verlengia
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Lipids 39:857-64. 2004
  6. ncbi request reprint Toxicity of a soybean oil emulsion on human lymphocytes and neutrophils
    Maria Fernanda Cury-Boaventura
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, and the Division of Clinical Emergency, Faculty of Medicine, University of Sao Paulo, Av Prof Lineu Prestes 1524, CEP 05508 900 São Paulo, Brazil
    JPEN J Parenter Enteral Nutr 30:115-23. 2006
  7. ncbi request reprint Genes regulated by arachidonic and oleic acids in Raji cells
    Rozangela Verlengia
    Methodist University of Piracicaba, Faculty of Sciences of Health, Physical Education, Sao Paulo, Brazil
    Lipids 38:1157-65. 2003
  8. ncbi request reprint Effect of olive oil-based emulsion on human lymphocyte and neutrophil death
    Maria Fernanda Cury-Boaventura
    Post Graduate Program in Human Movement Science, Biological Sciences and Health Center, Cruzeiro do Sul University, Sao Paulo, Brazil
    JPEN J Parenter Enteral Nutr 32:81-7. 2008
  9. doi request reprint Induction of lymphocyte death by short- and long-duration triathlon competitions
    Adriana Cristina Levada-Pires
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Med Sci Sports Exerc 41:1896-901. 2009
  10. doi request reprint Effects of exercise on leukocyte death: prevention by hydrolyzed whey protein enriched with glutamine dipeptide
    Maria Fernanda Cury-Boaventura
    Post Graduate Program in Human Movement Science, Physical Education Post Graduate Studies, Biological Sciences and Health Center, Cruzeiro do Sul University, Rua Galvão Bueno, 868, Sao Paulo, CEP 01506 000, Brazil
    Eur J Appl Physiol 103:289-94. 2008

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Regulation of interleukin-2 signaling by fatty acids in human lymphocytes
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil
    J Lipid Res 48:2009-19. 2007
    ..The inhibition of JAK1, JAK3, STAT5, ERK1/2, and Akt phosphorylation caused by DHA, SA, and PA is associated with an alteration of CD25 expression at the cell surface...
  2. ncbi request reprint Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte function
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Av Prof Lineu Prestes, 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
    Clin Nutr 25:923-38. 2006
    ..The effect of a docosahexaenoic acid (DHA)-rich fish oil (FO) supplementation on human leukocyte function was investigated...
  3. ncbi request reprint Regulation of human lymphocyte proliferation by fatty acids
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Cell Biochem Funct 25:305-15. 2007
    ..In conclusion, PA, SA, DHA and EPA decreased lymphocyte proliferation, whereas OA and LA stimulated it at non-toxic concentrations...
  4. doi request reprint Comparative effects of DHA and EPA on cell function
    Renata Gorjao
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Pharmacol Ther 122:56-64. 2009
    ..Substantial improvement in the therapeutic usage of omega-3 fatty acid-rich FO will be possible with the discovery of the different mechanisms of actions of DHA and EPA...
  5. ncbi request reprint Effects of EPA and DHA on proliferation, cytokine production, and gene expression in Raji cells
    Rozangela Verlengia
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Lipids 39:857-64. 2004
    ..However, remarkable differences were observed between DHA and EPA, demonstrating that specific effects of these FA may be responsible for the marked differences in edible oil effects on immune function in vivo reported by others...
  6. ncbi request reprint Toxicity of a soybean oil emulsion on human lymphocytes and neutrophils
    Maria Fernanda Cury-Boaventura
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, and the Division of Clinical Emergency, Faculty of Medicine, University of Sao Paulo, Av Prof Lineu Prestes 1524, CEP 05508 900 São Paulo, Brazil
    JPEN J Parenter Enteral Nutr 30:115-23. 2006
    ..In this study, the toxicity of a lipid emulsion rich (60%) in triacylglycerol of omega-6 polyunsaturated fatty acids on leukocytes from healthy volunteers was investigated...
  7. ncbi request reprint Genes regulated by arachidonic and oleic acids in Raji cells
    Rozangela Verlengia
    Methodist University of Piracicaba, Faculty of Sciences of Health, Physical Education, Sao Paulo, Brazil
    Lipids 38:1157-65. 2003
    ..These results led us to conclude that the effect of these FA on B-lymphocytes includes regulation of gene expression. Thus, diets enriched with fat containing OA or AA may affect B lymphocyte function in vivo...
  8. ncbi request reprint Effect of olive oil-based emulsion on human lymphocyte and neutrophil death
    Maria Fernanda Cury-Boaventura
    Post Graduate Program in Human Movement Science, Biological Sciences and Health Center, Cruzeiro do Sul University, Sao Paulo, Brazil
    JPEN J Parenter Enteral Nutr 32:81-7. 2008
    ..In this study, the toxicity of an olive oil-based emulsion (OOE) on lymphocytes and neutrophils from healthy volunteers was investigated...
  9. doi request reprint Induction of lymphocyte death by short- and long-duration triathlon competitions
    Adriana Cristina Levada-Pires
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Med Sci Sports Exerc 41:1896-901. 2009
    ..The effect of triathlon competitions on death of lymphocytes from elite athletes was investigated...
  10. doi request reprint Effects of exercise on leukocyte death: prevention by hydrolyzed whey protein enriched with glutamine dipeptide
    Maria Fernanda Cury-Boaventura
    Post Graduate Program in Human Movement Science, Physical Education Post Graduate Studies, Biological Sciences and Health Center, Cruzeiro do Sul University, Rua Galvão Bueno, 868, Sao Paulo, CEP 01506 000, Brazil
    Eur J Appl Physiol 103:289-94. 2008
    ..MGln supplementation partially prevented lymphocyte apoptosis induced by exhaustive exercise possibly by a protective effect on mitochondrial function...
  11. doi request reprint Gene expression reprogramming protects macrophage from septic-induced cell death
    Edielle Sant Anna Melo
    Emergency Medicine Department, Medical School, University of Sao Paulo, Sao Paulo, Brazil
    Mol Immunol 47:2587-93. 2010
    ..Thus, in the current study we provide evidence for the selective reprogramming of the gene expression of cell death pathways during LPS tolerance and link these changes to protection from cell death and enhanced survival rates...
  12. ncbi request reprint Comparative effects of eicosapentaenoic acid and docosahexaenoic acid on proliferation, cytokine production, and pleiotropic gene expression in Jurkat cells
    Rozangela Verlengia
    Methodist University of Piracicaba, Faculty of Physical Education, Faculdade de Educação Física, Sao Paulo, Brazil
    J Nutr Biochem 15:657-65. 2004
    ..Marked differences were observed between the effects of EPA and DHA, indicating that it is an over-simplification to generalize the effects of n-3 fatty acids...
  13. doi request reprint Fish oil supplementation for two generations increases insulin sensitivity in rats
    Sandro M Hirabara
    Institute of Physical Activity Sciences and Sport, Cruzeiro do Sul University, Sao Paulo, Brazil
    J Nutr Biochem 24:1136-45. 2013
    ....
  14. ncbi request reprint Oxidative state in platelets and erythrocytes in aging and Alzheimer's disease
    Elisa Mitiko Kawamoto
    Department of Pharmacology, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    Neurobiol Aging 26:857-64. 2005
    ..SNP increased cGMP platelets production in all groups. In conclusion, we demonstrated in platelets and erythrocytes a disruption in systemic modulation of oxidative stress in aging and with more intensity in AD...
  15. ncbi request reprint Mechanisms by which fatty acids regulate leucocyte function
    Thais Martins De Lima
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Clin Sci (Lond) 113:65-77. 2007
    ....
  16. doi request reprint UPR-mediated TRIB3 expression correlates with reduced AKT phosphorylation and inability of interleukin 6 to overcome palmitate-induced apoptosis in RINm5F cells
    José Edgar Nicoletti-Carvalho
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Prof Lineu Prestes Ave 1524, 05508 900 Sao Paulo, SP, Brazil
    J Endocrinol 206:183-93. 2010
    ..In this way, CHOP and ATF4 might mediate PA-induced TRIB3 expression and, by extension, the suppression of IL6 activation of pro-survival kinase AKT...
  17. doi request reprint Neutrophil death induced by a triathlon competition in elite athletes
    Adriana Cristina Levada-Pires
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Med Sci Sports Exerc 40:1447-54. 2008
    ..The effect of a triathlon competition on death of neutrophils from elite athletes was investigated...
  18. pmc Molecular targets related to inflammation and insulin resistance and potential interventions
    Sandro M Hirabara
    Institute of Physical Activity Sciences and Sports, Cruzeiro do Sul University, 01506 000 São Paulo, SP, Brazil
    J Biomed Biotechnol 2012:379024. 2012
    ..Finally, we address biotechnological studies for the development of new potential therapies and interventions...
  19. ncbi request reprint Changes of gene expression in electrically stimulated and contralateral rat soleus muscles
    Aurélio Pimenta
    National Institute of Obesity and Diabetes Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Avenida Prof Lineu Prestes 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
    Muscle Nerve 40:838-46. 2009
    ..These findings may indicate an association with tissue hypertrophy and metabolic adaptations induced by physical exercise training not only in the ES but also in the CL non-stimulated muscle, suggesting a cross-education phenomenon...
  20. ncbi request reprint Glutamine, gene expression, and cell function
    Rui Curi
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brasil
    Front Biosci 12:344-57. 2007
    ..In this review, we have attempted to identify some of the common mechanisms underlying glutamine dependent changes in gene and protein expression and cellular function...
  21. ncbi request reprint Mechanisms involved in Jurkat cell death induced by oleic and linoleic acids
    Maria Fernanda Cury-Boaventura
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, Av Prof Lineu Prestes, 1524, CEP 05508 900, University of Sao Paulo, SP, Brazil
    Clin Nutr 25:1004-14. 2006
    ..The mechanisms involved in the toxicity induced by OA and LA on Jurkat cells were determined in vitro...
  22. ncbi request reprint Influence of the bilayer composition on the binding and membrane disrupting effect of Polybia-MP1, an antimicrobial mastoparan peptide with leukemic T-lymphocyte cell selectivity
    Marcia Perez Dos Santos Cabrera
    UNESP Sao Paulo State University, Center of Studies of Social Insects, Institute of Biosciences, 13506 900 Rio Claro, SP, Brazil
    Biochemistry 51:4898-908. 2012
    ..Additionally, the absence of cholesterol resulted in enhanced pore activity. These findings may drive the selective toxicity of MP-1 to Jurkat cells...
  23. pmc Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function
    Amanda R Martins
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Professor Lineu Prestes 1524, Butanta, Sao Paulo, SP, Brazil
    Lipids Health Dis 11:30. 2012
    ....
  24. ncbi request reprint Comparative toxicity of oleic and linoleic acid on human lymphocytes
    Maria F Cury-Boaventura
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, Av Prof Lineu Prestes, 1524, CEP 05508 900, University of Sao Paulo, SP, Brazil
    Life Sci 78:1448-56. 2006
    ..OA may offer an immunological less problematic alternative to LA with respect to fatty acid composition of parenteral nutritional emulsions...
  25. ncbi request reprint Effect of arachidonic acid on proliferation, cytokines production and pleiotropic genes expression in Jurkat cells--a comparison with oleic acid
    Rozangela Verlengia
    Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
    Life Sci 73:2939-51. 2003
    ..Therefore, the effect of AA on T-lymphocyte function does involve regulation of expression of important genes, whereas oleic acid did not markedly affect gene expression of Jurkat cells...
  26. doi request reprint Endotoxin tolerance: selective alterations in gene expression and protection against lymphocyte death
    Edielle S Melo
    Emergency Medicine Department, Medical School, University of Sao Paulo, Sao Paulo, Brazil
    Immunobiology 215:435-42. 2010
    ..These alterations may play a significant role in the observed protection of the animals from a subsequent lethal polymicrobial sepsis challenge...
  27. pmc Chronic inflammation and neutrophil activation as possible causes of joint diseases in ballet dancers
    Leandro da Silva Borges
    Instituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13 andar, Bloco B, 01506 000 Liberdade, Sao Paulo, SP, Brazil
    Mediators Inflamm 2014:846021. 2014
    ..These findings are important in preventing the development of chronic lesions that are commonly observed in dancers, such as those with arthritis and synovitis. ..
  28. doi request reprint UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expression
    Carla R Bromati
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
    Am J Physiol Regul Integr Comp Physiol 300:R92-100. 2011
    ..The UPR is likely to counteract prosurvival actions of PRL by reducing pAKT through ATF4/CHOP-induced TRB3 expression...
  29. ncbi request reprint Apolipoprotein E genotype is related to nitric oxide production in platelets
    Tania Marcourakis
    Department of Clinical Chemistry and Toxicology, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Brazil
    Cell Biochem Funct 26:852-8. 2008
    ..These results suggest a possible influence of APOE genotype on nitric oxide (NO) production that might enhance the effects of age-related specific factor(s) associated with neurodegenerative disorders...
  30. ncbi request reprint Effect of a single session of electrical stimulation on activity and expression of citrate synthase and antioxidant enzymes in rat soleus muscle
    Aurélio da Silva Pimenta
    Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
    Eur J Appl Physiol 102:119-26. 2007
    ..This increase in expression of CAT may play an important role in counteracting the potential deleterious effects of elevated oxidative stress induced by a high oxidative demand in skeletal muscles subjected to exercise training...