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Genomes and Genes | Renata GorjaoSummaryCountry: Brazil Publications
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Publications
Comparative effects of DHA and EPA on cell functionRenata Gorjao
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
Pharmacol Ther 122:56-64. 2009..Substantial improvement in the therapeutic usage of omega-3 fatty acid-rich FO will be possible with the discovery of the different mechanisms of actions of DHA and EPA...
Effect of docosahexaenoic acid-rich fish oil supplementation on human leukocyte functionRenata Gorjao
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Av Prof Lineu Prestes, 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
Clin Nutr 25:923-38. 2006..The effect of a docosahexaenoic acid (DHA)-rich fish oil (FO) supplementation on human leukocyte function was investigated...- Regulation of interleukin-2 signaling by fatty acids in human lymphocytesRenata Gorjao
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil
J Lipid Res 48:2009-19. 2007..The inhibition of JAK1, JAK3, STAT5, ERK1/2, and Akt phosphorylation caused by DHA, SA, and PA is associated with an alteration of CD25 expression at the cell surface... - Regulation of human lymphocyte proliferation by fatty acidsRenata Gorjao
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
Cell Biochem Funct 25:305-15. 2007..In conclusion, PA, SA, DHA and EPA decreased lymphocyte proliferation, whereas OA and LA stimulated it at non-toxic concentrations... - Toxicity of a soybean oil emulsion on human lymphocytes and neutrophilsMaria Fernanda Cury-Boaventura
Department of Physiology and Biophysics, Institute of Biomedical Sciences, and the Division of Clinical Emergency, Faculty of Medicine, University of Sao Paulo, Av Prof Lineu Prestes 1524, CEP 05508 900 São Paulo, Brazil
JPEN J Parenter Enteral Nutr 30:115-23. 2006..In this study, the toxicity of a lipid emulsion rich (60%) in triacylglycerol of omega-6 polyunsaturated fatty acids on leukocytes from healthy volunteers was investigated... - Effect of olive oil-based emulsion on human lymphocyte and neutrophil deathMaria Fernanda Cury-Boaventura
Post Graduate Program in Human Movement Science, Biological Sciences and Health Center, Cruzeiro do Sul University, Sao Paulo, Brazil
JPEN J Parenter Enteral Nutr 32:81-7. 2008..In this study, the toxicity of an olive oil-based emulsion (OOE) on lymphocytes and neutrophils from healthy volunteers was investigated... - Effects of exercise on leukocyte death: prevention by hydrolyzed whey protein enriched with glutamine dipeptideMaria Fernanda Cury-Boaventura
Post Graduate Program in Human Movement Science, Physical Education Post Graduate Studies, Biological Sciences and Health Center, Cruzeiro do Sul University, Rua Galvão Bueno, 868, Sao Paulo, CEP 01506 000, Brazil
Eur J Appl Physiol 103:289-94. 2008..MGln supplementation partially prevented lymphocyte apoptosis induced by exhaustive exercise possibly by a protective effect on mitochondrial function... - Induction of lymphocyte death by short- and long-duration triathlon competitionsAdriana Cristina Levada-Pires
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
Med Sci Sports Exerc 41:1896-901. 2009..The effect of triathlon competitions on death of lymphocytes from elite athletes was investigated... - Gene expression reprogramming protects macrophage from septic-induced cell deathEdielle Sant Anna Melo
Emergency Medicine Department, Medical School, University of Sao Paulo, Sao Paulo, Brazil
Mol Immunol 47:2587-93. 2010..Thus, in the current study we provide evidence for the selective reprogramming of the gene expression of cell death pathways during LPS tolerance and link these changes to protection from cell death and enhanced survival rates... - Comparative effects of eicosapentaenoic acid and docosahexaenoic acid on proliferation, cytokine production, and pleiotropic gene expression in Jurkat cellsRozangela Verlengia
Methodist University of Piracicaba, Faculty of Physical Education, Faculdade de Educação Física, Sao Paulo, Brazil
J Nutr Biochem 15:657-65. 2004..Marked differences were observed between the effects of EPA and DHA, indicating that it is an over-simplification to generalize the effects of n-3 fatty acids... - Mechanisms by which fatty acids regulate leucocyte functionThais Martins De Lima
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
Clin Sci (Lond) 113:65-77. 2007.... - UPR-mediated TRIB3 expression correlates with reduced AKT phosphorylation and inability of interleukin 6 to overcome palmitate-induced apoptosis in RINm5F cellsJosé Edgar Nicoletti-Carvalho
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Prof Lineu Prestes Ave 1524, 05508 900 Sao Paulo, SP, Brazil
J Endocrinol 206:183-93. 2010..In this way, CHOP and ATF4 might mediate PA-induced TRIB3 expression and, by extension, the suppression of IL6 activation of pro-survival kinase AKT... - Neutrophil death induced by a triathlon competition in elite athletesAdriana Cristina Levada-Pires
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
Med Sci Sports Exerc 40:1447-54. 2008..The effect of a triathlon competition on death of neutrophils from elite athletes was investigated... 
Molecular targets related to inflammation and insulin resistance and potential interventionsSandro M Hirabara
Institute of Physical Activity Sciences and Sports, Cruzeiro do Sul University, 01506 000 São Paulo, SP, Brazil
J Biomed Biotechnol 2012:379024. 2012..Finally, we address biotechnological studies for the development of new potential therapies and interventions...- Mechanisms involved in Jurkat cell death induced by oleic and linoleic acidsMaria Fernanda Cury-Boaventura
Department of Physiology and Biophysics, Institute of Biomedical Sciences, Av Prof Lineu Prestes, 1524, CEP 05508 900, University of Sao Paulo, SP, Brazil
Clin Nutr 25:1004-14. 2006..The mechanisms involved in the toxicity induced by OA and LA on Jurkat cells were determined in vitro... - Glutamine, gene expression, and cell functionRui Curi
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brasil
Front Biosci 12:344-57. 2007..In this review, we have attempted to identify some of the common mechanisms underlying glutamine dependent changes in gene and protein expression and cellular function... - Changes of gene expression in electrically stimulated and contralateral rat soleus musclesAurélio Pimenta
National Institute of Obesity and Diabetes Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Avenida Prof Lineu Prestes 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
Muscle Nerve 40:838-46. 2009..These findings may indicate an association with tissue hypertrophy and metabolic adaptations induced by physical exercise training not only in the ES but also in the CL non-stimulated muscle, suggesting a cross-education phenomenon... - Influence of the bilayer composition on the binding and membrane disrupting effect of Polybia-MP1, an antimicrobial mastoparan peptide with leukemic T-lymphocyte cell selectivityMarcia Perez Dos Santos Cabrera
UNESP Sao Paulo State University, Center of Studies of Social Insects, Institute of Biosciences, 13506 900 Rio Claro, SP, Brazil
Biochemistry 51:4898-908. 2012..Additionally, the absence of cholesterol resulted in enhanced pore activity. These findings may drive the selective toxicity of MP-1 to Jurkat cells... - Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial functionAmanda R Martins
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Professor Lineu Prestes 1524, Butanta, Sao Paulo, SP, Brazil
Lipids Health Dis 11:30. 2012.... - Comparative toxicity of oleic and linoleic acid on human lymphocytesMaria F Cury-Boaventura
Department of Physiology and Biophysics, Institute of Biomedical Sciences, Av Prof Lineu Prestes, 1524, CEP 05508 900, University of Sao Paulo, SP, Brazil
Life Sci 78:1448-56. 2006..OA may offer an immunological less problematic alternative to LA with respect to fatty acid composition of parenteral nutritional emulsions... - Effect of arachidonic acid on proliferation, cytokines production and pleiotropic genes expression in Jurkat cells--a comparison with oleic acidRozangela Verlengia
Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1524, 05508 900, Butanta, Sao Paulo, SP, Brazil
Life Sci 73:2939-51. 2003..Therefore, the effect of AA on T-lymphocyte function does involve regulation of expression of important genes, whereas oleic acid did not markedly affect gene expression of Jurkat cells... - Endotoxin tolerance: selective alterations in gene expression and protection against lymphocyte deathEdielle S Melo
Emergency Medicine Department, Medical School, University of Sao Paulo, Sao Paulo, Brazil
Immunobiology 215:435-42. 2010..These alterations may play a significant role in the observed protection of the animals from a subsequent lethal polymicrobial sepsis challenge... - Effect of a single session of electrical stimulation on activity and expression of citrate synthase and antioxidant enzymes in rat soleus muscleAurélio da Silva Pimenta
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil
Eur J Appl Physiol 102:119-26. 2007..This increase in expression of CAT may play an important role in counteracting the potential deleterious effects of elevated oxidative stress induced by a high oxidative demand in skeletal muscles subjected to exercise training... - Apolipoprotein E genotype is related to nitric oxide production in plateletsTania Marcourakis
Department of Clinical Chemistry and Toxicology, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Brazil
Cell Biochem Funct 26:852-8. 2008..These results suggest a possible influence of APOE genotype on nitric oxide (NO) production that might enhance the effects of age-related specific factor(s) associated with neurodegenerative disorders... - UPR induces transient burst of apoptosis in islets of early lactating rats through reduced AKT phosphorylation via ATF4/CHOP stimulation of TRB3 expressionCarla R Bromati
Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Brazil
Am J Physiol Regul Integr Comp Physiol 300:R92-100. 2011..The UPR is likely to counteract prosurvival actions of PRL by reducing pAKT through ATF4/CHOP-induced TRB3 expression...