Research Topics

Genomes and Genes


Mário Luiz Conte da Frota


Country: Brazil


  1. da Frota Junior M, Pires A, Zeidán Chuliá F, Bristot I, Lopes F, de Bittencourt Pasquali M, et al. In vitro optimization of retinoic acid-induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox. Mol Cell Biochem. 2011;358:325-34 pubmed publisher
    ..Therefore, our data demonstrate that concomitant decreases in basal reactive oxygen species (ROS) production could exert a positive effect on the neuritogenic process of RA-treated SH-SY5Y cells. ..
  2. da Frota M, Braganhol E, Cañedo A, Klamt F, Apel M, Mothes B, et al. Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line. Invest New Drugs. 2009;27:440-6 pubmed publisher
    ..This is a first report demonstrating that marine sponge extracts of P. janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway. ..
  3. request reprint
    Frota M, Klamt F, Dal Pizzol F, Schiengold M, Moreira J. Retinol-induced mdr1 and mdr3 modulation in cultured rat Sertoli cells is attenuated by free radical scavengers. Redox Rep. 2004;9:161-5 pubmed
    ..The results suggest that retinol may play an important role in the modulation of the mdr gene family in cultured rat Sertoli cells and that these effects appear to be mediated by ROS...