Zuleica B Fortes
de Queiroz E, Akamine E, de Carvalho M, Sampaio S, Fortes Z. Metformin reduces the Walker-256 tumor development in obese-MSG rats via AMPK and FOXO3a. Life Sci. 2015;121:78-87 pubmed publisher
..Our data allow us to suggest that metformin, reducing the stimulatory effect of obesity on tumor development, has a potential role in the management of cancers. ..
Bomfim G, Echem C, Martins C, Costa T, Sartoretto S, dos Santos R, et al
. Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats. Life Sci. 2015;122:1-7 pubmed publisher
..Together, these results suggest that TLR4 is a key player in hypertension and vascular inflammatory process by a NFÎºB signaling pathway. ..