L F Drager

Summary

Country: Brazil

Publications

  1. doi request reprint Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil Electronic address
    J Am Coll Cardiol 62:569-76. 2013
  2. doi request reprint The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 904, Sao Paulo, Brazil
    Atherosclerosis 208:490-5. 2010
  3. doi request reprint Sleep-related changes in hemodynamic and autonomic regulation in human hypertension
    Luciano F Drager
    Hypertension Unit Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, Zip Code 05403 904, Sao Paulo, Brazil
    J Hypertens 27:1655-63. 2009
  4. doi request reprint Characteristics and predictors of obstructive sleep apnea in patients with systemic hypertension
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Sao Paulo, Brazil
    Am J Cardiol 105:1135-9. 2010
  5. doi request reprint Additive effects of obstructive sleep apnea and hypertension on early markers of carotid atherosclerosis
    Luciano F Drager
    Hypertension Unit, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Hypertension 53:64-9. 2009
  6. pmc The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    PLoS ONE 5:e12065. 2010
  7. ncbi request reprint Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Respir Crit Care Med 176:706-12. 2007
  8. doi request reprint Obstructive sleep apnea, masked hypertension, and arterial stiffness in men
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Hypertens 23:249-54. 2010
  9. doi request reprint Lack of circadian variation of pulse wave velocity measurements in healthy volunteers
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Clin Hypertens (Greenwich) 13:19-22. 2011
  10. ncbi request reprint Phenotypic characteristics associated with hypertension in patients with obstructive sleep apnea
    L F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Hum Hypertens 20:523-8. 2006

Collaborators

Detail Information

Publications24

  1. doi request reprint Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil Electronic address
    J Am Coll Cardiol 62:569-76. 2013
    ..Taken together, these results support the concept that OSA exacerbates the cardiometabolic risk attributed to obesity and the metabolic syndrome. Recognition and treatment of OSA may decrease the cardiovascular risk in obese patients. ..
  2. doi request reprint The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 904, Sao Paulo, Brazil
    Atherosclerosis 208:490-5. 2010
    ..The main objective of this study is to determine the impact of OSA on markers of atherosclerosis in patients with MS...
  3. doi request reprint Sleep-related changes in hemodynamic and autonomic regulation in human hypertension
    Luciano F Drager
    Hypertension Unit Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, Zip Code 05403 904, Sao Paulo, Brazil
    J Hypertens 27:1655-63. 2009
    ..The present study investigates the hemodynamic and autonomic regulation during sleep-awake transitions and across different sleep cycles in patients with essential hypertension...
  4. doi request reprint Characteristics and predictors of obstructive sleep apnea in patients with systemic hypertension
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Sao Paulo, Brazil
    Am J Cardiol 105:1135-9. 2010
    ....
  5. doi request reprint Additive effects of obstructive sleep apnea and hypertension on early markers of carotid atherosclerosis
    Luciano F Drager
    Hypertension Unit, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Hypertension 53:64-9. 2009
    ....
  6. pmc The impact of obstructive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome
    Luciano F Drager
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    PLoS ONE 5:e12065. 2010
    ..Therefore, it is not clear whether OSA exacerbates the metabolic abnormalities in a representative sample of patients with MetS...
  7. ncbi request reprint Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Respir Crit Care Med 176:706-12. 2007
    ..Atherosclerosis is a key mechanism for these cardiovascular events. Recent cross-sectional studies showed the presence of early signs of atherosclerosis in patients with OSA who were free of comorbidities...
  8. doi request reprint Obstructive sleep apnea, masked hypertension, and arterial stiffness in men
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Hypertens 23:249-54. 2010
    ..However, it is not clear whether the frequency of masked hypertension in patients with OSA and whether OSA have an independent role on arterial stiffness taking into account ambulatory blood pressure (BP) monitoring (ABPM)...
  9. doi request reprint Lack of circadian variation of pulse wave velocity measurements in healthy volunteers
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Clin Hypertens (Greenwich) 13:19-22. 2011
    ..016). In young healthy volunteers, there is no significant circadian variation of carotid-femoral PWV. These findings support the concept that it does not appear mandatory to perform PWV measurements at exactly the same period of the day...
  10. ncbi request reprint Phenotypic characteristics associated with hypertension in patients with obstructive sleep apnea
    L F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Hum Hypertens 20:523-8. 2006
    ..We concluded that increasing age and BMI, familial history of hypertension as well as female gender are phenotypic characteristics associated with hypertension among OSA patients with similar disease severity...
  11. doi request reprint The effects of continuous positive airway pressure on prehypertension and masked hypertension in men with severe obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, 05403 904 São Paulo, Brazil
    Hypertension 57:549-55. 2011
    ..In conclusion, effective CPAP therapy promotes significant reduction in the frequency of prehypertension and masked hypertension by promoting significant blood pressure reductions in patients with severe obstructive sleep apnea...
  12. ncbi request reprint Early signs of atherosclerosis in obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit and Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 900 São Paulo, Brazil
    Am J Respir Crit Care Med 172:613-8. 2005
    ..Recent studies have shown that OSA is associated with multiple markers of endothelial damage. We hypothesized that OSA affects functional and structural properties of large arteries, contributing to atherosclerosis progression...
  13. ncbi request reprint Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodeling
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar 44, CEP 05403 904, Sao Paulo, Brazil
    Chest 131:1379-86. 2007
    ..We sought to investigate the impact of OSA, hypertension, and their association with arterial stiffness and heart structure...
  14. doi request reprint Obstructive sleep apnea is highly prevalent and correlates with impaired glycemic control in consecutive patients with the metabolic syndrome
    Luciano F Drager
    Hypertension Unit, University of Sao Paulo Medical School, Sao Paulo, Brazil
    J Cardiometab Syndr 4:89-95. 2009
    ..001) and apnea-hypopnea index (P=.03). The prevalence of OSA is in the same range as all the individual components of MS and is independently associated with impaired glycemic control...
  15. doi request reprint Reciprocal interactions of obstructive sleep apnea and hypertension associated with ACE I/D polymorphism in males
    Renata G Koyama
    Department of Psychobiology, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Sleep Med 10:1107-11. 2009
    ..However, ACE is a pleiotropic gene that has several influences, including skeletal muscle and control of ventilation. We therefore tested the hypothesis that ACE polymorphism influences OSA severity...
  16. pmc Consequences of comorbid sleep apnea in the metabolic syndrome--implications for cardiovascular risk
    Ivani C Trombetta
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Sleep 33:1193-9. 2010
    ..We examined how the presence of OSA in patients with MetSyn affected hemodynamic and autonomic variables associated with poor cardiovascular outcome...
  17. doi request reprint Obstructive sleep apnea is common and independently associated with atrial fibrillation in patients with hypertrophic cardiomyopathy
    Rodrigo P Pedrosa
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, Av Enéas Carvalho de Aguiar, 44, Sao Paulo, Brazil
    Chest 137:1078-84. 2010
    ..Obstructive sleep apnea (OSA) is independently associated with heart remodeling and arrhythmias in other populations. We hypothesized that OSA is common and is associated with heart remodeling and AF in patients with HCM...
  18. pmc Effects of exercise training in patients with chronic heart failure and sleep apnea
    Linda M Ueno
    School of Arts, Sciences and Humanities, University of Sao Paulo, Sao Paulo, Brazil
    Sleep 32:637-47. 2009
    ..To test the effects of exercise training on sleep and neurovascular control in patients with systolic heart failure with and without sleep disordered breathing...
  19. doi request reprint Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome
    Kátia C Guimarães
    Sleep Laboratory, Pulmonary Division, Heart Institute InCor, University of Sao Paulo Medical School, Av Dr Eneas Carvalho de Aguiar, 44, CEP 05403 904, Sao Paulo, Brazil
    Am J Respir Crit Care Med 179:962-6. 2009
    ..Preliminary results suggested that oropharyngeal exercises derived from speech therapy may be an effective treatment option for patients with moderate OSAS...
  20. pmc Effects of sinoaortic denervation on hemodynamic parameters during natural sleep in rats
    Neide P Silveira
    Hypertension Unit of the Heart Institute InCor do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil
    Sleep 31:328-33. 2008
    ..To analyze the role of arterial baroreflex on hemodynamic changes during synchronized and desynchronized sleep phases of natural sleep in rats...
  21. ncbi request reprint Obstructive sleep apnea and atherosclerosis: a new paradigm
    Geraldo Lorenzi-Filho
    Am J Respir Crit Care Med 175:1219-21. 2007
  22. ncbi request reprint Sympathetic activity, heart failure, obesity, and metabolic syndrome: is there any role for obstructive sleep apnea?
    Luciano F Drager
    Hypertension 49:e38; author reply e39. 2007
  23. ncbi request reprint Letter regarding article by Law et al, "headaches and the treatment of blood pressure: results from a meta-analysis of 94 randomized placebo-controlled trials with 24,000 participants"
    Luciano F Drager
    Circulation 113:e164. 2006
  24. ncbi request reprint [Genetic aspects of endocrine hypertensive disorders]
    Luciano F Drager
    Unidade de Hipertensão do InCor, HCFMUSP, USP, Sao Paulo, SP
    Arq Bras Endocrinol Metabol 48:659-65. 2004
    ..These syndromes are of particular interest since they highlight the importance of cell pathways that can be affected in the more common forms of hypertension...