Janete M Cerutti
Bastos A, Oler G, Nozima B, MoysÃ©s R, Cerutti J. BRAF V600E and decreased NIS and TPO expression are associated with aggressiveness of a subgroup of papillary thyroid microcarcinoma. Eur J Endocrinol. 2015;173:525-40 pubmed publisher
..We believe that our findings will help to decide the realistic usefulness of BRAF V600E mutation as a preoperative marker of poor prognosis in small PTC, primarily in microPTC. ..
Cordioli M, Moraes L, Cury A, Cerutti J. Are we really at the dawn of understanding sporadic pediatric thyroid carcinoma?. Endocr Relat Cancer. 2015;22:R311-24 pubmed publisher
..The aim of this review is to present an extensive literature review with emphasis on the molecular differences between pediatric sporadic and radiation-exposed differentiated thyroid carcinomas and adult population. ..
Pinheiro Dos Santos M, Bastos A, da Costa V, Delcelo R, Lindsey S, Colozza Gama G, et al
. LIMD2 Is Overexpressed in BRAF V600E-Positive Papillary Thyroid Carcinomas and Matched Lymph Node Metastases. Endocr Pathol. 2018;29:222-230 pubmed publisher
..Our data suggest that LIMD2 may play an important role in the metastatic process of PTC, predominantly in BRAF V600E-positive tumors. ..
Cerutti J, Oler G, Delcelo R, Gerardt R, Michaluart P, de Souza S, et al
. PVALB, a new Hürthle adenoma diagnostic marker identified through gene expression. J Clin Endocrinol Metab. 2011;96:E151-60 pubmed publisher
..This improved test would help physicians rapidly focus treatment on true malignancies and avoid unnecessary treatment of benign tumors, simultaneously improving medical care and reducing costs. ..
Mendes T, Nozima B, Budu A, de Souza R, Braga Catroxo M, Delcelo R, et al
. PVALB diminishes [Ca2+] and alters mitochondrial features in follicular thyroid carcinoma cells through AKT/GSK3Î² pathway. Endocr Relat Cancer. 2016;23:769-82 pubmed publisher
..Finally, PVALB expression coincides with Ca(2+) deposits in HCA tissues. Our data support the hypothesis that the loss of PVALB plays a role in the pathogenesis of thyroid tumors. ..
Bastos A, de Jesus A, Cerutti J. ETV6-NTRK3 and STRN-ALK kinase fusions are recurrent events in papillary thyroid cancer of adult population. Eur J Endocrinol. 2018;178:85-93 pubmed publisher
..Further analysis is needed to define if they can also be useful for prognosis and guiding therapy. ..
Latini F, Hemerly J, Freitas B, Oler G, Riggins G, Cerutti J. ABI3 ectopic expression reduces in vitro and in vivo cell growth properties while inducing senescence. BMC Cancer. 2011;11:11 pubmed publisher
..These results also suggest that the pathways through which ABI3 works should be further characterized. ..