Leda R Castilho

Summary

Country: Brazil

Publications

  1. ncbi request reprint Cell retention devices for suspended-cell perfusion cultures
    Leda R Castilho
    GBF German National Research Center for Biotechnology, Biochemical Engineering Division, Braunschweig
    Adv Biochem Eng Biotechnol 74:129-69. 2002
  2. ncbi request reprint An integrated process for mammalian cell perfusion cultivation and product purification using a dynamic filter
    Leda R Castilho
    GBF German Research Centre for Biotechnology, Biochemical Engineering Division, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Biotechnol Prog 18:776-81. 2002
  3. ncbi request reprint CFD-aided design of a dynamic filter for mammalian cell separation
    Leda R Castilho
    Biochemical Engineering Division, GBF German Research Centre for Biotechnology, Braunschweig, Germany
    Biotechnol Bioeng 83:514-24. 2003
  4. ncbi request reprint Lipase production by solid-state fermentation: cultivation conditions and operation of tray and packed-bed bioreactors
    Melissa L E Gutarra
    Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Centro de Tecnologia CT, Laboratory 549 2, Ilha do Fundao, CEP 21945 970, Rio de Janeiro RJ, Brazil
    Appl Biochem Biotechnol 121:105-16. 2005
  5. ncbi request reprint High-yield Bacillus subtilis protease production by solid-state fermentation
    Valeria F Soares
    Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Brazil
    Appl Biochem Biotechnol 121:311-9. 2005

Collaborators

  • Melissa L E Gutarra
  • Valeria F Soares
  • Denise M G Freire
  • Elisa D C Cavalcanti
  • Elba P S Bon
  • Geraldo L Sant'anna

Detail Information

Publications5

  1. ncbi request reprint Cell retention devices for suspended-cell perfusion cultures
    Leda R Castilho
    GBF German National Research Center for Biotechnology, Biochemical Engineering Division, Braunschweig
    Adv Biochem Eng Biotechnol 74:129-69. 2002
    ..The advantages and disadvantages of each of these methods will be discussed...
  2. ncbi request reprint An integrated process for mammalian cell perfusion cultivation and product purification using a dynamic filter
    Leda R Castilho
    GBF German Research Centre for Biotechnology, Biochemical Engineering Division, Mascheroder Weg 1, D 38124 Braunschweig, Germany
    Biotechnol Prog 18:776-81. 2002
    ....
  3. ncbi request reprint CFD-aided design of a dynamic filter for mammalian cell separation
    Leda R Castilho
    Biochemical Engineering Division, GBF German Research Centre for Biotechnology, Braunschweig, Germany
    Biotechnol Bioeng 83:514-24. 2003
    ..5 h), and no indication of fouling was observed. It was shown that the designed dynamic filter is able to effectively avoid both cell damage and membrane fouling, and thus can be used for mammalian cell harvesting and perfusion...
  4. ncbi request reprint Lipase production by solid-state fermentation: cultivation conditions and operation of tray and packed-bed bioreactors
    Melissa L E Gutarra
    Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Centro de Tecnologia CT, Laboratory 549 2, Ilha do Fundao, CEP 21945 970, Rio de Janeiro RJ, Brazil
    Appl Biochem Biotechnol 121:105-16. 2005
    ..Maximum lipase activities obtained in these bioreactors (26.4 U/g) were 30% higher than in tray-type reactors...
  5. ncbi request reprint High-yield Bacillus subtilis protease production by solid-state fermentation
    Valeria F Soares
    Department of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Brazil
    Appl Biochem Biotechnol 121:311-9. 2005
    ..These results indicate that this bacterial strain shows a high biotechnological potential for protease production in solid-state fermentation...