Joao T Marques


Affiliation: Belo Horizonte
Country: Brazil


  1. Donald C, Varjak M, Aguiar E, Marques J, Sreenu V, Schnettler E, et al. Antiviral RNA Interference Activity in Cells of the Predatory Mosquito, Toxorhynchites amboinensis. Viruses. 2018;10: pubmed publisher
    ..Understanding their ability to manage arboviral infections will be advantageous when assessing these and similar species as biological control agents. ..
  2. Olmo R, Ferreira A, Izidoro Toledo T, Aguiar E, de Faria I, de Souza K, et al. Control of dengue virus in the midgut of Aedes aegypti by ectopic expression of the dsRNA-binding protein Loqs2. Nat Microbiol. 2018;3:1385-1393 pubmed publisher
    ..Together, our data reveal a mechanism of tissue-specific regulation of the mosquito siRNA pathway controlled by Loqs2. ..
  3. Aguiar E, Olmo R, Marques J. Virus-derived small RNAs: molecular footprints of host-pathogen interactions. Wiley Interdiscip Rev RNA. 2016;7:824-837 pubmed publisher
    ..WIREs RNA 2016, 7:824-837. doi: 10.1002/wrna.1361 For further resources related to this article, please visit the WIREs website. ..
  4. Sedda L, Vilela A, Aguiar E, Gaspar C, Gonçalves A, Olmo R, et al. The spatial and temporal scales of local dengue virus transmission in natural settings: a retrospective analysis. Parasit Vectors. 2018;11:79 pubmed publisher
    ..Nevertheless, localized vector control at distances lower than 2.5 km around premises with infected vectors in densely populated areas are not likely to be effective. ..
  5. Marques J, Wang J, Wang X, de Oliveira K, Gao C, Aguiar E, et al. Functional specialization of the small interfering RNA pathway in response to virus infection. PLoS Pathog. 2013;9:e1003579 pubmed publisher
    ..We speculate that this unique framework might be necessary for a prompt and efficient antiviral response. ..
  6. Soares Z, Gonçalves A, de Oliveira K, Marques J. Viral RNA recognition by the Drosophila small interfering RNA pathway. Microbes Infect. 2014;16:1013-21 pubmed publisher
    ..This antiviral response in fruit flies can help understand general principles of nucleic acid recognition. ..
  7. Aguiar E, Olmo R, Paro S, Ferreira F, de Faria I, Todjro Y, et al. Sequence-independent characterization of viruses based on the pattern of viral small RNAs produced by the host. Nucleic Acids Res. 2015;43:6191-206 pubmed publisher
    ..Additionally, our results suggest that virus detection utilizing small RNAs can also be applied to vertebrates, although not as efficiently as to plants and insects. ..
  8. Marques J, Imler J. The diversity of insect antiviral immunity: insights from viruses. Curr Opin Microbiol. 2016;32:71-76 pubmed publisher
    ..Viral suppressors can offer unique perspective on host pathways and emphasize the importance of RNA interference, apoptosis, but also NF-?B pathways and translation control in insect antiviral immunity. ..