M L Andersen

Summary

Country: Brazil

Publications

  1. pmc Dietary fish oil did not prevent sleep deprived rats from a reduction in adipose tissue adiponectin gene expression
    Ana Barbosa Marcondes de Mattos
    Department of Physiology, Federal University of Sao Paulo, Sao Paulo, Brazil
    Lipids Health Dis 7:43. 2008
  2. pmc Validation of commonly used reference genes for sleep-related gene expression studies
    Kil S Lee
    Associação Fundo de Incentivo à Psicofarmacologia, Sao Paulo, Brazil
    BMC Mol Biol 10:45. 2009
  3. doi request reprint The association of testosterone, sleep, and sexual function in men and women
    Monica L Andersen
    Departmento de Psicobiologia, Universidade Federal de Sao Paulo, Brazil
    Brain Res 1416:80-104. 2011
  4. ncbi request reprint Influence of chronic cocaine treatment and sleep deprivation on sexual behavior and neurogenesis of the male rat
    Monica L Andersen
    Psychobiology Department, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:1224-9. 2007
  5. pmc Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats
    Monica L Andersen
    Psychobiology Department, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Napoleão de Barros, Clementino, Sao Paulo, SP, Brazil
    Reprod Biol Endocrinol 5:7. 2007
  6. ncbi request reprint Involvement of nitric oxide in cocaine-induced erections and ejaculations after paradoxical sleep deprivation
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:652-7. 2007
  7. doi request reprint Angiotensin-converting enzyme polymorphism and erectile dysfunction complaints in the Brazilian population
    Monica L Andersen
    Universidade Federal de Sao Paulo UNIFESP, Department of Psychobiology, Sao Paulo, SP, Brazil
    J Sex Med 7:2791-7. 2010
  8. doi request reprint Androgen receptor CAG repeat polymorphism is not associated with erectile dysfunction complaints, gonadal steroids, and sleep parameters: data from a population-based survey
    Monica L Andersen
    Departamento de Psicobiologia, Universidade Federal de Sa o Paulo, Sao Paulo, Brazil
    J Androl 32:524-9. 2011
  9. doi request reprint Hormonal profile, the PROGINS polymorphism, and erectile dysfunction complaints: data from a population-based survey
    Monica L Andersen
    Departamento de Psicobiologia Universidade Federal de São Paulo, Sao Paulo, Brazil
    Fertil Steril 95:621-4. 2011
  10. ncbi request reprint Cocaine-induced genital reflexes in paradoxical sleep deprived rats: Indications of mediation by serotonin receptors
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:496-502. 2007

Collaborators

Detail Information

Publications92

  1. pmc Dietary fish oil did not prevent sleep deprived rats from a reduction in adipose tissue adiponectin gene expression
    Ana Barbosa Marcondes de Mattos
    Department of Physiology, Federal University of Sao Paulo, Sao Paulo, Brazil
    Lipids Health Dis 7:43. 2008
    ..Thus, the stress induced by sleep deprivation lead to a desbalance of adiponectin gene expression...
  2. pmc Validation of commonly used reference genes for sleep-related gene expression studies
    Kil S Lee
    Associação Fundo de Incentivo à Psicofarmacologia, Sao Paulo, Brazil
    BMC Mol Biol 10:45. 2009
    ....
  3. doi request reprint The association of testosterone, sleep, and sexual function in men and women
    Monica L Andersen
    Departmento de Psicobiologia, Universidade Federal de Sao Paulo, Brazil
    Brain Res 1416:80-104. 2011
    ....
  4. ncbi request reprint Influence of chronic cocaine treatment and sleep deprivation on sexual behavior and neurogenesis of the male rat
    Monica L Andersen
    Psychobiology Department, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:1224-9. 2007
    ..These findings show that long-term cocaine treatment from brain development through adulthood had a marked effect on sexual responses and neuronal proliferation...
  5. pmc Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats
    Monica L Andersen
    Psychobiology Department, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Napoleão de Barros, Clementino, Sao Paulo, SP, Brazil
    Reprod Biol Endocrinol 5:7. 2007
    ..We also extended our study to examine how PSD affect steroid hormone concentrations involved in genital events in both experimental models...
  6. ncbi request reprint Involvement of nitric oxide in cocaine-induced erections and ejaculations after paradoxical sleep deprivation
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:652-7. 2007
    ..As nitric oxide (NO) is involved in penile erectile (PE) function and also influences the sleep-wake cycle, we speculated that NO could play a role in PE and ejaculation of paradonical sleep deprivation (PSD) rats...
  7. doi request reprint Angiotensin-converting enzyme polymorphism and erectile dysfunction complaints in the Brazilian population
    Monica L Andersen
    Universidade Federal de Sao Paulo UNIFESP, Department of Psychobiology, Sao Paulo, SP, Brazil
    J Sex Med 7:2791-7. 2010
    ..Limited and conflicting data have been published on the influence of this genetic variant on the pathophysiology of erectile dysfunction (ED)...
  8. doi request reprint Androgen receptor CAG repeat polymorphism is not associated with erectile dysfunction complaints, gonadal steroids, and sleep parameters: data from a population-based survey
    Monica L Andersen
    Departamento de Psicobiologia, Universidade Federal de Sa o Paulo, Sao Paulo, Brazil
    J Androl 32:524-9. 2011
    ..AR CAG repeat polymorphism is not associated with ED complaints, gonadal steroids, and sleep parameters in men from a population-based sample in Brazil...
  9. doi request reprint Hormonal profile, the PROGINS polymorphism, and erectile dysfunction complaints: data from a population-based survey
    Monica L Andersen
    Departamento de Psicobiologia Universidade Federal de São Paulo, Sao Paulo, Brazil
    Fertil Steril 95:621-4. 2011
    ..To evaluate a potential association among the hormonal profile, PROGINS polymorphism, and erectile dysfunction (ED) complaints in a large population-based sample in Sao Paulo, Brazil...
  10. ncbi request reprint Cocaine-induced genital reflexes in paradoxical sleep deprived rats: Indications of mediation by serotonin receptors
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:496-502. 2007
    ..Taken together, the results suggest that serotonergic receptors play an important role in genital reflexes induced by cocaine in sleep deprived males...
  11. ncbi request reprint Effects of progesterone on sleep: a possible pharmacological treatment for sleep-breathing disorders?
    M L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Curr Med Chem 13:3575-82. 2006
    ..This review attempts to outline the specific role of progesterone in normal sleep and breathing as well as its possible therapeutic effects in the treatment of sleep-disordered breathing...
  12. doi request reprint Prevalence of erectile dysfunction complaints associated with sleep disturbances in Sao Paulo, Brazil: a population-based survey
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Brazil
    Sleep Med 11:1019-24. 2010
    ....
  13. ncbi request reprint Sexsomnia: abnormal sexual behavior during sleep
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Sao Paulo, SP, Brazil
    Brain Res Rev 56:271-82. 2007
    ..The characteristics of several individuals described in literature including their family/personal history of parasomnia as well as the abnormal behaviors occurring during sleep are reported...
  14. ncbi request reprint Effect of sildenafil (Viagra) on the genital reflexes of paradoxical sleep-deprived male rats
    M L Andersen
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 40:1473-80. 2007
    ..The stimulation of the genital reflexes by sildenafil did not result in potentiating effects in PSD rats...
  15. doi request reprint Genetics of erectile dysfunction: a review of the interface between sex and molecular biomarkers
    Monica L Andersen
    Departamento de Psicobiologia Universidade Federal de São Paulo, Sao Paulo, Brazil
    J Sex Med 8:3030-9. 2011
    ..The potential use of genetic variations as biomarkers in the management of current and future conditions is generating considerable excitement in health care for disorders such as erectile dysfunction (ED)...
  16. doi request reprint Increased susceptibility to development of anhedonia in rats with chronic peripheral nerve injury: involvement of sleep deprivation?
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 33:960-6. 2009
    ..Accordingly, this anhedonic condition that constitutes to the core manifestation of depressive states did not occur in response to a single episode of total RSD...
  17. doi request reprint Paradoxical sleep deprivation influences sexual behavior in female rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de São Paulo UNIFESP São Paulo, SP, Brazil
    J Sex Med 6:2162-72. 2009
    ..Rodents have been used as models to examine the effects of sleep deprivation on hormonal and behavioral changes. Among the many comorbidities common to sleep disorders, sexual behavior remains the least well studied...
  18. doi request reprint Electrophysiological correlates of sleep disturbance induced by acute and chronic administration of D-amphetamine
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Brain Res 1249:162-72. 2009
    ..Given that some of these abnormalities are observed in individuals with BD, this animal model can provide a means to investigate neurobiological aspects of sleep disturbance in BD, as well as their response to mood stabilizers...
  19. pmc Altered sleep patterns and physiologic characteristics in spontaneous dwarf rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, Brazil
    Comp Med 59:344-9. 2009
    ..Immunoblotting data showed that the levels of ceruloplasmin in serum were lower in dwarf rats. Our findings provide insight into pathologic processes related to growth hormone deficiency...
  20. doi request reprint Association analysis of endothelial nitric oxide synthase G894T gene polymorphism and erectile dysfunction complaints in a population-based survey
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, SP, Brazil
    J Sex Med 7:1229-36. 2010
    ....
  21. doi request reprint Are endogenous sex hormones related to DNA damage in paradoxically sleep-deprived female rats?
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Vila Clementino, SP, Sao Paulo, Brazil
    Horm Behav 57:216-21. 2010
    ..In conclusion, our data are consistent with the notion that genetic damage in the form of DNA breakage in brain cells induced by sleep deprivation overrides the effects related to endogenous female sex hormones...
  22. doi request reprint Effects of sleep loss on sleep architecture in Wistar rats: gender-specific rebound sleep
    M L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, R Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 32:975-83. 2008
    ..Thus, the females and males displayed distinct patterns as a result of sleep disruption...
  23. ncbi request reprint Possible participation of D3 and D4 dopaminergic receptors on genital reflexes induced by cocaine in paradoxical sleep deprived male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo, Brazil
    Scand J Psychol 48:443-7. 2007
    ..Although our studies indicate that there is a relevant participation of D3 receptors in male sexual function, D4 receptors seem not to exert an essential role in this model...
  24. ncbi request reprint Association of paradoxical sleep deprivation and ecstasy (MDMA) enhances genital reflexes in male rats
    M L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Behav Brain Res 170:287-92. 2006
    ..Thus, the present results showed a great enhancement of the genital reflexes of PSD rats that might have occurred due to serotoninergic alterations induced by this illicit substance when associated to sleep deprivation...
  25. doi request reprint Distinct gender-related sleep pattern in an acute model of TMJ pain
    T C B Schütz
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Rua Napoleao de Barros, 925, Vila Clementino, SP 04024 002, Sao Paulo, SP, Brazil
    J Dent Res 88:471-6. 2009
    ..Behavior and sleep architecture in the females remained unaffected. Our results suggest that females and males present distinct responses to an acute model of orofacial pain...
  26. ncbi request reprint Influence of temporomandibular joint pain on sleep patterns: role of nitric oxide
    T C B Schütz
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Rua Napoleao de Barros, 925 Vila Clementino SP 04024 002, SP, Brazil
    J Dent Res 83:693-7. 2004
    ..L-arginine did not alter sleep parameters. Thus, L-NAME improved sleep efficiency, whereas L-arginine did not modify it, suggesting the involvement of nitric oxide in painful temporomandibular joint conditions...
  27. doi request reprint Sleep pattern in an experimental model of osteoarthritis
    A Silva
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Rua Napoleao de Barros, 925, Vila Clementino, 04024 002 São Paulo, SP, Brazil
    Pain 140:446-55. 2008
    ..Thus, pain associated with the rat OA model causes alterations in sleep architecture by disrupting the sleep pattern...
  28. doi request reprint Sleep loss and acute drug abuse can induce DNA damage in multiple organs of mice
    T A Alvarenga
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Hum Exp Toxicol 30:1275-81. 2011
    ..Taken together, our results suggest that cocaine and ecstasy/MDMA act as potent genotoxins in multiple organs of mice when associated with sleep loss...
  29. ncbi request reprint Effects of progesterone blockade over cocaine-induced genital reflexes of paradoxical sleep-deprived male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Horm Behav 47:477-84. 2005
    ..In addition, mifepristone administration induced a significant decrease in the duration of PS episodes at all doses. These data suggest that progesterone exerts an essential role in erectile response induced by cocaine in PSD male rats...
  30. ncbi request reprint Effects of paradoxical sleep deprivation and cocaine on genital reflexes in hyperlipidic-fed rats
    Monica L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina, R Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Pharmacol Biochem Behav 81:758-63. 2005
    ..Although there were no hormonal alterations, the findings showed that a long-term HD might modify the stimulating effects of cocaine in potentiating genital reflexes in PSD rats...
  31. ncbi request reprint Effects of paradoxical sleep deprivation on genital reflexes in five rat strains
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP EPM, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Horm Behav 49:173-80. 2006
    ..In the other strains, this hormone was significantly lower compared to the Wistar and Long-Evans PSD. This study demonstrates that genital reflexes are differently influenced by PSD associated to cocaine in five rat strains...
  32. doi request reprint Polysomnographic study of the prevalence of sleep bruxism in a population sample
    M Maluly
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Dent Res 92:97S-103S. 2013
    ..These findings demonstrate the prevalence of SB in a population sampled by PSG, the gold standard methodology in the investigation of sleep disorders, combined with validated questionnaires...
  33. ncbi request reprint Sleep pattern in rats under different stress modalities
    L A Papale
    Department of Psychobiology Universidade Federal de São Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Brain Res 1060:47-54. 2005
    ..Immobilization decreased PS throughout the 4 days of the stress sessions. Thus, the data suggest that different stress modalities result in distinct sleep responses, with immobilization producing the most dramatic alterations...
  34. doi request reprint Distinct effects of acute and chronic sleep loss on DNA damage in rats
    M L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 33:562-7. 2009
    ..Since DNA damage is an important step in events leading to genomic instability, this study represents a relevant contribution to the understanding of the potential health risks associated with sleep deprivation...
  35. ncbi request reprint Effects of COX-2 inhibitor in temporomandibular joint acute inflammation
    T C B Schütz
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, SP, Brazil
    J Dent Res 86:475-9. 2007
    ..These parameters returned progressively to those found in the SHAM group. Etoricoxib improved the sleep parameters, suggesting the involvement of the cyclo-oxygenase-2 enzyme in acute inflammation of the TMJ, specifically in REM sleep...
  36. ncbi request reprint Gender and age differences in polysomnography findings and sleep complaints of patients referred to a sleep laboratory
    A Silva
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 41:1067-75. 2008
    ..We did not find significant differences between genders in the percentage of REM sleep and sleep efficiency. The results of the current study suggest that there are specific gender differences in sleep pattern...
  37. pmc Dopamine transporter regulation during four nights of REM sleep deprivation followed by recovery--an in vivo molecular imaging study in humans
    R C S Martins
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Brazil
    Sleep 33:243-51. 2010
    ..To assess the influence of total or selective REM sleep deprivation on the dopamine transporter (DAT) densities and sleep patterns of healthy volunteers...
  38. ncbi request reprint Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in intact and ovariectomized rats compared with male rats
    I B Antunes
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros 925, Vila Clementino, 04024 002 São Paulo, SP, Brazil
    Behav Brain Res 176:187-92. 2007
    ..Similarities in blood parameters observed between OVX and male rats are likely due to the suppression of ovarian hormone release after ovariectomy...
  39. ncbi request reprint Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats
    R C S Martins
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 41:68-77. 2008
    ..Therefore, our results suggest that abuse of these psychostimulants in a PSD paradigm aggravates their impact on sleep patterns...
  40. doi request reprint Does the reproductive cycle influence sleep patterns in women with sleep complaints?
    H Hachul
    Departments of Gynecology, Universidade Federal de Sao Paulo, Brazil
    Climacteric 13:594-603. 2010
    ..The aim of the present study was to investigate how prominent gynecological factors (regular/irregular menstrual cycle, premenstrual complaints, or menopause) can influence both subjective and objective sleep data...
  41. ncbi request reprint Cocaine-induced genital reflexes during paradoxical sleep deprivation and recovery
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925 Vila Clementino, SP 04024 002, Sao Paulo, Brazil
    Physiol Behav 78:255-9. 2003
    ..Even short periods of PSD probably cause supersensitivity of dopamine (DA) receptors and exacerbate the effects of cocaine on dopaminergic pathways to induce frequent PE and EJ...
  42. ncbi request reprint Effects of different substance misuse in genital reflexes of paradoxical sleep deprived male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP EPM, Sao Paulo, Brazil
    Scand J Psychol 48:191-5. 2007
    ..These findings show that Delta(9)THC, alcohol and caffeine when administrated isolated did not produce alterations in genital reflexes in the PSD male rats...
  43. ncbi request reprint Effects of long-term food restriction on genital reflexes in paradoxically sleep-deprived male rats
    Tathiana A F Alvarenga
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Brain Res 1115:148-54. 2006
    ..Further studies are warranted to dissect the effect of food restriction on sexual behavior...
  44. ncbi request reprint Does paradoxical sleep deprivation and cocaine induce penile erection and ejaculation in old rats?
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Brazil
    Addict Biol 7:285-90. 2002
    ..The interaction of PSD and cocaine probably enhances dopamine transmission in the brain and may elicit penile erection in old rats...
  45. ncbi request reprint The effects of dopaminergic agonists on genital reflexes in paradoxical sleep-deprived male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino, SP 04024 002, Sao Paulo, Brazil
    Physiol Behav 84:205-10. 2005
    ..These DA agonists showed distinct effects in sexual response suggesting that these effects are probably due to PSD-induced DA receptor supersensitivity even though different mechanisms are involved...
  46. doi request reprint Whole blood genome-wide gene expression profile in males after prolonged wakefulness and sleep recovery
    R Pellegrino
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Physiol Genomics 44:1003-12. 2012
    ..Thus, the present findings confirm that the effects of sleep loss are not restricted to the brain and can occur intensely in peripheral tissues...
  47. ncbi request reprint Different stress modalities result in distinct steroid hormone responses by male rats
    M L Andersen
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 37:791-7. 2004
    ..Thus, the data suggest that different stress modalities result in distinct steroid hormone responses, with PSD and footshock being the most similar...
  48. ncbi request reprint Noradrenergic system interacts with genital reflexes induced by cocaine in paradoxical sleep-deprived male rats
    Monica L Andersen
    Department of Psychobiology, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Behav Neurosci 119:473-82. 2005
    ..The results showed that noradrenergic drugs inhibited genital reflexes in PSD rats, with distinct responses in relation to their respective action over the adrenoceptor...
  49. ncbi request reprint Acute cocaine effects in paradoxical sleep deprived male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925 Vila Clementino, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 29:245-51. 2005
    ..Thus, the present study indicated that the behavioural effects of cocaine could be modified by PSD. This in turn may have relevant implications in the cocaine effect in abusers under sleep deprived condition...
  50. ncbi request reprint Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats
    L A Papale
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 41:782-8. 2008
    ..Although the mechanism by which ethanol induces PS suppression is not fully understood, these data suggest that the cholinergic system is not the only system involved in this interaction...
  51. doi request reprint Stress, immunity and skin collagen integrity: evidence from animal models and clinical conditions
    V Kahan
    Department of Psychobiology, Universidade Federal de São Paulo UNIFESP São Paulo, SP, Brazil
    Brain Behav Immun 23:1089-95. 2009
    ..This review will briefly present comprehensive data from both animal and human studies delineating processes that modulate alterations in collagen in general, and will treat in more detail the consequences of stress on skin collagen...
  52. ncbi request reprint Effects of paradoxical sleep deprivation on blood parameters associated with cardiovascular risk in aged rats
    M L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Exp Gerontol 39:817-24. 2004
    ..These results indicate that PSD has significant but heterogeneous physiological effects in aged rats and may intensify certain aging-related effects which contribute to cardiovascular disease risk while attenuating others...
  53. ncbi request reprint Cholinergic mechanisms in cocaine-induced genital reflexes in paradoxical sleep-deprived male rats
    M L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925, Villa Clementino, 4024 002, Sao Paulo, SP, Brazil
    Pharmacol Biochem Behav 77:525-31. 2004
    ..The data also suggest that the stimulating action of cocaine in potentiating the sexual effects in PSD rats does not override the effects of the cholinergic mechanisms of sexual behavior...
  54. ncbi request reprint Sleep alterations in an experimental orofacial pain model in rats
    T C B Schütz
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925 Vila Clementino, Sao Paulo, SP 04024 002, Brazil
    Brain Res 993:164-71. 2003
    ..001) were reduced reestablishing the normal sleep pattern. The results showed the reliability and usefulness of the temporomandibular joint pain model to characterize sleep disturbances related to pain and its response to indomethacin...
  55. ncbi request reprint Inhibitory effect of GABAergic drugs in cocaine-induced genital reflexes in paradoxical sleep-deprived male rats
    M L Andersen
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Pharmacol Biochem Behav 78:301-7. 2004
    ..These data show that GABAergic compounds inhibited PE in male PSD rats suggesting that this inhibition points to a differential role of GABA receptor subtypes...
  56. ncbi request reprint Effects of acute and chronic sleep loss on immune modulation of rats
    A Zager
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Am J Physiol Regul Integr Comp Physiol 293:R504-9. 2007
    ..Such alterations during sleep deprivation suggest only minor alterations of nonspecific immune parameters during acute PSD, and a significant impairment in cellular response during chronic SR...
  57. doi request reprint Food restriction or sleep deprivation: which exerts a greater influence on the sexual behaviour of male rats?
    Tathiana A Alvarenga
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Rua Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Behav Brain Res 202:266-71. 2009
    ....
  58. doi request reprint Impact of sex on hyperalgesia induced by sleep loss
    P Araujo
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Brazil
    Horm Behav 59:174-9. 2011
    ..This finding indicates that, although different periods of sleep deprivation change the nociceptive sensitivity in male and female mice, sex could influence hyperalgesia induced by chronic sleep loss...
  59. doi request reprint Does sleep deprivation and morphine influence wound healing?
    F Egydio
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, SP, Brazil
    Med Hypotheses 77:353-5. 2011
    ..Thus, it is important that future studies consider the paradigm of sleep curtailment when investigating the mechanisms involved in the process of skin healing in individuals who are dependent on morphine...
  60. ncbi request reprint Effects of morphine or naloxone on cocaine-induced genital reflexes in paradoxical sleep-deprived rats
    M L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Pharmacol Biochem Behav 79:515-21. 2004
    ..The findings suggest that the stimulating effects of cocaine in potentiating genital reflexes in PSD rats can be unidirectionally modified by opioidergic systems...
  61. ncbi request reprint Sleep deprivation reduces the lymphocyte count in a non-obese mouse model of type 1 diabetes mellitus
    F S Ruiz
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 40:633-7. 2007
    ..Since many cases of autoimmunity present reduced numbers of lymphocytes and, in this study, it was more evident in the NOD strain, our results suggest that SD should be considered a risk factor in the onset of autoimmune disorders...
  62. ncbi request reprint The effects of paradoxical sleep deprivation on estrous cycles of the female rats
    Isabela B Antunes
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, UNIFESP EPM, Rua Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Horm Behav 49:433-40. 2006
    ..These data indicate that PSD may modulate the ovarian hormone release through alterations in hormonal-neurochemical mechanisms...
  63. doi request reprint To what extent is sleep rebound effective in reversing the effects of paradoxical sleep deprivation on gene expression in the brain?
    Camila Guindalini
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Vila Clementino, SP, Brazil
    Behav Brain Res 201:53-8. 2009
    ..In summary, our results provide a unique set of transcripts that might be specific related to regulation of paradoxical sleep phase and sleep homeostasis processes, as well as to the biological basis of sleep disorders...
  64. ncbi request reprint The effect of apomorphine on genital reflexes in male rats deprived of paradoxical sleep
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Rua Napoleao de Barros, 925 Vila Clementino, São Paulo SP 04024 002, Brazil
    Physiol Behav 80:211-5. 2003
    ..We suggest that the potentiating effects of apomorphine on PE are likely due to PSD-induced DA receptor supersensitivity...
  65. doi request reprint The association between TNF-α and erectile dysfunction complaints
    G Matos
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Andrology 1:872-8. 2013
    ..95 pg/mL) and the presence of ED complaints. The results showed that there was an association between TNF-α levels and ED complaints in men independent of OSAS. ..
  66. ncbi request reprint Sleep disturbance induced by substance P in mice
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Brazil
    Behav Brain Res 167:212-8. 2006
    ..To examine the reversal of SP effects, eight mice were administered with an NK1 receptor antagonist before SP administration. Prior administration of the NK1 antagonist prevented the disturbances in sleep...
  67. ncbi request reprint Distinct effects of paradoxical sleep deprivation and cocaine administration on sexual behavior in male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Vila Clementino, Brazil
    Addict Biol 7:251-3. 2002
    ..These findings are due probably to PSD causing supersensitivity of dopamine (DA) receptors exacerbating the cocaine actions on dopaminergic pathways inducing penile erection and ejaculation...
  68. pmc The role of the substantia nigra pars compacta in regulating sleep patterns in rats
    Marcelo M S Lima
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    PLoS ONE 2:e513. 2007
    ..Evidence contained in the literature lends support to the hypothesis that the dopaminergic nigrostriatal pathway is closely involved in the regulation of sleep patterns...
  69. doi request reprint Blockage of dopaminergic D(2) receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation
    Marcelo M S Lima
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Behav Brain Res 188:406-11. 2008
    ..In conclusion we report a particular action of the dopaminergic neurotransmission in REM sleep relying on D(2) activation...
  70. doi request reprint Single exposure to cocaine or ecstasy induces DNA damage in brain and other organs of mice
    Tathiana A Alvarenga
    Department of Psychobiology, Universidade Federal de Sao Paulo, Brazil
    Addict Biol 15:96-9. 2010
    ..Extensive genotoxic damage was induced by cocaine or MDMA at the highest doses used in liver cells. Brain cells were affected by all doses administrated. These findings demonstrate that cocaine and MDMA are potent genotoxins...
  71. doi request reprint Clinical profile of menopausal insomniac women referred to sleep laboratory
    Helena Hachul
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Brazil
    Acta Obstet Gynecol Scand 88:422-7. 2009
    ..The primary purpose of this study was to assess the overall clinical profile of menopausal women complaining of insomnia who were referred to a sleep laboratory...
  72. doi request reprint The influence of orofacial pain on sleep pattern: a review of theory, animal models and future directions
    Teresa C B Schütz
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Rua Napoleao de Barros 925, Vila Clementino, Sao Paulo, SP, Brazil
    Sleep Med 10:822-8. 2009
    ....
  73. doi request reprint Modulation of sickness behavior by sleep: the role of neurochemical and neuroinflammatory pathways in mice
    Adriano Zager
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP EPM, Sao Paulo, Brazil
    Eur Neuropsychopharmacol 19:589-602. 2009
    ..The study provides some insights into how the sleep-wake cycle affects the expression of sickness behavior induced by LPS...
  74. doi request reprint Effects of hormone therapy with estrogen and/or progesterone on sleep pattern in postmenopausal women
    Helena Hachul
    Department of Gynecology, Federal University of Sao Paulo UNIFESP EPM, Sao Paulo, Brazil
    Int J Gynaecol Obstet 103:207-12. 2008
    ..To investigate the effects of estrogen and progesterone on sleep in postmenopausal women...
  75. ncbi request reprint Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research
    Sergio Tufik
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    An Acad Bras Cienc 81:521-38. 2009
    ..More specifically, we highlight relevant experimental studies and our group's contribution over the last three decades...
  76. doi request reprint Differential sympathetic activation induced by intermittent hypoxia and sleep loss in rats: Action of angiotensin (1-7)
    Juliana C Perry
    Department of Psychobiology, Universidade Federal de Sao Paulo, SP, Brazil
    Auton Neurosci 160:32-6. 2011
    ..These results suggest that CIH and sleep restriction impaired the cardiovascular system, and its association to sleep loss can modify these effects by partially restoring circulating angiotensin (1-7)...
  77. ncbi request reprint Role of hippocampal oxidative stress in memory deficits induced by sleep deprivation in mice
    R H Silva
    Department of Pharmacology, Universidade Federal de Sao Paulo UNIFESP, Rua Botucatu, 862 Ed Leal Prado, CEP 04023 062 São Paulo, SP, Brazil
    Neuropharmacology 46:895-903. 2004
    ..The results indicate an important role of hippocampal oxidative stress in passive avoidance memory deficits induced by sleep deprivation in mice...
  78. ncbi request reprint The reciprocal interaction between sleep and type 2 diabetes mellitus: facts and perspectives
    R C Martins
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 41:180-7. 2008
    ..Furthermore, major advances in care coupled with healthy lifestyles can ensure a higher quality of life for people with diabetes...
  79. ncbi request reprint Gentle handling temporarily increases c-Fos in the substantia nigra pars compacta
    C A Santos
    Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Braz J Med Biol Res 41:920-5. 2008
    ..This finding suggests that this range (2-5-fold) of neuronal activation may serve as a marker of SD...
  80. ncbi request reprint Endocrinological and catecholaminergic alterations during sleep deprivation and recovery in male rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, Sao Paulo, SP, Brazil
    J Sleep Res 14:83-90. 2005
    ..Thus, SD showed long lasting, differential effects upon these neurochemicals suggesting that each has its own pattern of responses to SD as well as variable periods of recovery...
  81. pmc Sleep complaints in the adult Brazilian population: a national survey based on screening questions
    Lia Rita A Bittencourt
    Department of Psychobiology, Universidade Federal Sao Paulo, UNIFESP, Sao Paulo, Brazil
    J Clin Sleep Med 5:459-63. 2009
    ..The aim of the current survey was to investigate the prevalence of sleep complaints in a randomized cluster sample of the Brazilian population...
  82. ncbi request reprint Pain hypersensitivity induced by paradoxical sleep deprivation is not due to altered binding to brain mu-opioid receptors
    Danielle C Nascimento
    Department of Psychobiology, Universidade Federal de Sao Paulo, Escola Paulista de Medicina Unifesp EPM, R Napoleao de Barros, 925, V Clementino 04024 002, Sao Paulo, SP, Brazil
    Behav Brain Res 178:216-20. 2007
    ..However, the fact no changes were seen in [3H]DAMGO binding indicates that mechanisms other than altered mu-opioid binding must be sought to explain the phenomenon...
  83. doi request reprint Can poor sleep affect skin integrity?
    V Kahan
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, SP, Brazil
    Med Hypotheses 75:535-7. 2010
    ..In fact, the reduction of sleep time affects the composition and integrity of various systems. Thus, we hypothesized that lack of sleep as well as other types of stress can impair skin integrity...
  84. ncbi request reprint Chronic stress may modulate periodontal disease: a study in rats
    Daiane C Peruzzo
    School of Dentistry at Piracicaba, State University of Campinas, Piracicaba, SP, Brazil
    J Periodontol 79:697-704. 2008
    ....
  85. ncbi request reprint Sleep deprivation abolishes the locomotor stimulant effect of ethanol in mice
    Nilza P Araujo
    Departamento de Farmacologia, Universidade Federal de Sao Paulo, Sao Paulo, SP 04023 062, Brazil
    Brain Res Bull 69:332-7. 2006
    ..The present findings demonstrate that the acute effect of ETOH on mice's motor activity are behaviorally complex and can be specifically modulated by SD...
  86. ncbi request reprint Influence of long-term food restriction on sleep pattern in male rats
    Tathiana A F Alvarenga
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino SP 04024 002, Sao Paulo, Brazil
    Brain Res 1057:49-56. 2005
    ..These results suggest that dietary restriction, regardless to the feeding schedule, caused increase in total sleep time, during the active period...
  87. doi request reprint Paradoxical sleep deprivation impairs acquisition, consolidation, and retrieval of a discriminative avoidance task in rats
    Tathiana A Alvarenga
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino, SP 04021 002, Sao Paulo, Brazil
    Neurobiol Learn Mem 90:624-32. 2008
    ..In addition, it suggests that PSD effects on acquisition and consolidation do not seem to be related to other behavioral alterations induced by this procedure...
  88. doi request reprint Age-related changes during a paradigm of chronic sleep restriction
    Luciane de Souza
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino 04024 002, Sao Paulo, SP, Brazil
    Behav Brain Res 214:201-5. 2010
    ..Furthermore, sleep latency and mean wake bout length progressively increased during the protocol. These findings indicate that older rats have an inability to restore their sleep patterns during extended sleep deprivation...
  89. ncbi request reprint Evaluation of acute and chronic treatments with Harpagophytum procumbens on Freund's adjuvant-induced arthritis in rats
    Monica L Andersen
    Department of Psychobiology, Universidade Federal de Sao Paulo, Rua Napoleao de Barros, 925, Vila Clementino, SP 04024 002 São Paulo, Brazil
    J Ethnopharmacol 91:325-30. 2004
    ..Thus, the data showed anti-inflammatory and peripheral analgesic properties of Harpagophytum procumbens extract with all doses tested, thus confirming its indication for inflammatory processes...
  90. doi request reprint Influence of genotype on dopamine transporter availability in human striatum and sleep architecture
    Camila Guindalini
    Department of Psychobiology Universidade Federal de São Paulo, Escola Paulista de Medicina Unifesp EPM, Sao Paulo, Brazil
    Psychiatry Res 179:238-40. 2010
    ..No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and [(⁹⁹m)Tc]TRODAT-1 was observed...
  91. doi request reprint The influence of obstructive sleep apnea on the expression of glycerol-3-phosphate dehydrogenase 1 gene
    Camila Guindalini
    Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, Brazil
    Exp Biol Med (Maywood) 235:52-6. 2010
    ..This suggests that GPD1 may not play a major role in the OSA manifestation...
  92. doi request reprint Sleep pattern in an experimental model of chronic kidney disease
    Camila Hirotsu
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Am J Physiol Renal Physiol 299:F1379-88. 2010
    ..Collectively, these metabolic and cardiovascular changes were associated with the persistent alterations in sleep architecture observed in CKD rats...