Kathleen T Brady

Summary

Publications

  1. pmc Substance use disorders and anxiety: a treatment challenge for social workers
    Kathleen T Brady
    Department of Psychiatry, Clinical Neuroscience Division, Medical University of South Carolina, Charleston, SC 29425, USA
    Soc Work Public Health 28:407-23. 2013
  2. pmc Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
  3. pmc Volitional reduction of anterior cingulate cortex activity produces decreased cue craving in smoking cessation: a preliminary real-time fMRI study
    Xingbao Li
    Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
    Addict Biol 18:739-48. 2013
  4. doi Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory
    Bryan K Tolliver
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 36:106-13. 2010
  5. ncbi The impact of alcohol dependence and posttraumatic stress disorder on cold pressor task response
    Kathleen T Brady
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, South Carolina 29425, USA
    J Stud Alcohol 67:700-6. 2006
  6. pmc Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Affect Disord 110:167-73. 2008
  7. pmc Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation
    Sudie E Back
    Department of Psychiatry, Clinical Neuroscience Division, Medical University of South Carolina, 67 President Street, PO Box 250861, Charleston, SC, USA
    Psychoneuroendocrinology 33:560-8. 2008
  8. pmc Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues
    Angela E Waldrop
    Medical University of South Carolina, 67 President St, Charleston, SC 29403, United States
    Psychoneuroendocrinology 35:798-806. 2010
  9. pmc Reactivity to laboratory stress provocation predicts relapse to cocaine
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Drug Alcohol Depend 106:21-7. 2010
  10. ncbi Symptom improvement in co-occurring PTSD and alcohol dependence
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Charleston, South Carolina 29425, USA
    J Nerv Ment Dis 194:690-6. 2006

Detail Information

Publications64

  1. pmc Substance use disorders and anxiety: a treatment challenge for social workers
    Kathleen T Brady
    Department of Psychiatry, Clinical Neuroscience Division, Medical University of South Carolina, Charleston, SC 29425, USA
    Soc Work Public Health 28:407-23. 2013
    ..This article, written for social workers in a variety of practice settings, reviews the prevalence, diagnostic, and treatment issues at the interface of substance use disorders and anxiety disorders...
  2. pmc Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trials
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 69:1057-63. 2008
    ..To compare clinical variables in patients with rapid-cycling bipolar I or II disorder and a recent history of substance use disorder (SUD)...
  3. pmc Volitional reduction of anterior cingulate cortex activity produces decreased cue craving in smoking cessation: a preliminary real-time fMRI study
    Xingbao Li
    Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
    Addict Biol 18:739-48. 2013
    ..Further research is needed to determine the optimal parameters of neurofeedback rtfMRI, and whether it might eventually become a therapeutic tool for nicotine dependence...
  4. doi Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory
    Bryan K Tolliver
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 36:106-13. 2010
    ..In this study, clinical and demographic correlates of methamphetamine craving and the optimal conditions for its measurement in the laboratory are explored...
  5. ncbi The impact of alcohol dependence and posttraumatic stress disorder on cold pressor task response
    Kathleen T Brady
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, South Carolina 29425, USA
    J Stud Alcohol 67:700-6. 2006
    ..The objective of this study was to investigate HPA axis reactivity to the cold pressor task (CPT) among individuals with alcohol dependence, PTSD, and comorbid alcohol dependence and PTSD...
  6. pmc Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorder
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    J Affect Disord 110:167-73. 2008
    ..Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions...
  7. pmc Effects of gender and cigarette smoking on reactivity to psychological and pharmacological stress provocation
    Sudie E Back
    Department of Psychiatry, Clinical Neuroscience Division, Medical University of South Carolina, 67 President Street, PO Box 250861, Charleston, SC, USA
    Psychoneuroendocrinology 33:560-8. 2008
    ..In addition, there is some evidence for a more robust neuroendocrine and physiologic response to acute laboratory stress in women as compared to men...
  8. pmc Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues
    Angela E Waldrop
    Medical University of South Carolina, 67 President St, Charleston, SC 29403, United States
    Psychoneuroendocrinology 35:798-806. 2010
    ..Subjective and HPA-axis responses to a social evaluative stressor, the Trier Social Stress Test (TRIER), and in vivo cocaine-related cues were examined in the present study...
  9. pmc Reactivity to laboratory stress provocation predicts relapse to cocaine
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Drug Alcohol Depend 106:21-7. 2010
    ..Elevated levels of stress have been associated with relapse to cocaine; however, the nature of this association is not well understood...
  10. ncbi Symptom improvement in co-occurring PTSD and alcohol dependence
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Charleston, South Carolina 29425, USA
    J Nerv Ment Dis 194:690-6. 2006
    ....
  11. ncbi Stress reactivity: biological and subjective responses to the cold pressor and Trier Social stressors
    Aimee L McRae
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Hum Psychopharmacol 21:377-85. 2006
    ..The results suggest that the TSST results in a greater HPA response than the CPT; however, the CPT may have utility in diagnostically heterogeneous patients...
  12. pmc Influence of cocaine dependence and early life stress on pituitary-adrenal axis responses to CRH and the Trier social stressor
    Megan M Moran-Santa Maria
    Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States
    Psychoneuroendocrinology 35:1492-500. 2010
    ....
  13. pmc Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals
    Kathleen T Brady
    Department of Psychiatry and Behavioral Sciences, Clinical Neurosciences Division, Medical University of South Carolina, 67 President St, PO Box 250861, Charleston, SC 29425, USA
    Arch Gen Psychiatry 66:422-30. 2009
    ..Little is known about the response of cocaine-dependent individuals to CRH administration...
  14. pmc Impact of DCS-facilitated cue exposure therapy on brain activation to cocaine cues in cocaine dependence
    James J Prisciandaro
    Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Drug Alcohol Depend 132:195-201. 2013
    ....
  15. pmc Independent predictors for lifetime and recent substance use disorders in patients with rapid-cycling bipolar disorder: focus on anxiety disorders
    Keming Gao
    Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
    Am J Addict 19:440-9. 2010
    ....
  16. doi Impaired cognitive performance in subjects with methamphetamine dependence during exposure to neutral versus methamphetamine-related cues
    Bryan K Tolliver
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
    Am J Drug Alcohol Abuse 38:251-9. 2012
    ..Exposure to methamphetamine-related cues can elicit intense craving in chronic users of the drug, but the effects of exposure to drug cues on cognitive performance in these individuals are unknown...
  17. pmc A placebo-controlled trial of buspirone for the treatment of marijuana dependence
    Aimee L McRae-Clark
    Department of Psychiatry, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Drug Alcohol Depend 105:132-8. 2009
    ..054). Further study with buspirone in this population may be warranted; however, strategies to enhance study retention and improve outcome measurement should be considered in future trials...
  18. pmc Resisting the urge to smoke and craving during a smoking quit attempt on varenicline: results from a pilot fMRI study
    Karen J Hartwell
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Drug Alcohol Abuse 39:92-8. 2013
    ..Varenicline has been shown to reduce cigarette craving during a quit attempt...
  19. pmc Real-time fMRI in the treatment of nicotine dependence: a conceptual review and pilot studies
    Karen J Hartwell
    Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
    Psychol Addict Behav 27:501-9. 2013
    ..While rtfMRI feedback remains an intriguing possibility for the treatment of addictions, much work remains to be done in establishing its efficacy...
  20. pmc Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate
    James J Prisciandaro
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 36:490-6. 2012
    ..The present study examined the impact of depressive symptoms and alcohol craving on proximal alcohol use in patients with co-occurring bipolar disorder and alcohol dependence...
  21. ncbi Cold pressor task reactivity: predictors of alcohol use among alcohol-dependent individuals with and without comorbid posttraumatic stress disorder
    Kathleen T Brady
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 30:938-46. 2006
    ..This study investigated the relationship between subjective and neuroendocrine stress reactivity to the cold pressor task (CPT) and prospective alcohol use among individuals with alcohol dependence, with and without comorbid PTSD...
  22. pmc Relationship between child abuse and adult smoking
    Eve G Spratt
    Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USA
    Int J Psychiatry Med 39:417-26. 2009
    ..In this study, the relationship between severe childhood abuse and smoking were examined in a group of adults without significant psychopathology...
  23. pmc Motives for using: a comparison of prescription opioid, marijuana and cocaine dependent individuals
    Karen J Hartwell
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, United States
    Addict Behav 37:373-8. 2012
    ..The marked differences revealed in motives for drug use could be used in the development and implementation of specific treatment interventions for prescription opioid, marijuana and cocaine dependent individuals...
  24. ncbi Assessment of club drug use in a treatment-seeking sample of individuals with marijuana dependence
    Marcia L Verduin
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    Am J Addict 16:484-7. 2007
    ..This appears to be the first study to report on club drug use in treatment-seeking marijuana-dependent individuals. Clinical implications and directions for future research are discussed...
  25. pmc The impact of clinical and demographic variables on cognitive performance in methamphetamine-dependent individuals in rural South Carolina
    Kimber L Price
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29403, USA
    Am J Addict 20:447-55. 2011
    ..Characterization of the impact of clinical and/or demographic features on cognitive deficits could be important in guiding the development of treatment interventions...
  26. ncbi Differences in early onset alcohol use and heavy drinking among persons with childhood and adulthood trauma
    Angela E Waldrop
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA
    Am J Addict 16:439-42. 2007
    ....
  27. pmc Reduction of cue-induced craving through realtime neurofeedback in nicotine users: the role of region of interest selection and multiple visits
    Colleen A Hanlon
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Psychiatry Res 213:79-81. 2013
    ..g. ventral anterior cingulate cortex (vACC)) rather than increasing activity in regions involved in "resisting" (e.g. dorsal medial prefrontal cortex (dmPFC))...
  28. pmc Does alexithymia explain variation in cue-elicited craving reported by methamphetamine-dependent individuals?
    Michael E Saladin
    Department of Health Sciences and Research, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Addict 21:130-5. 2012
    ..Thus, the results suggest that increasing difficulty-identifying feelings may be associated with higher cue-elicited craving. Clinical implications for this finding are discussed...
  29. pmc Improving the transition from residential to outpatient addiction treatment: gender differences in response to supportive telephone calls
    Rickey E Carter
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 34:47-59. 2008
    ..The findings revealed that women were more likely than men to attend aftercare. This "gender effect" persisted after adjustment for a number of potential mediators...
  30. pmc A double blind, placebo-controlled study of the effects of post-retrieval propranolol on reconsolidation of memory for craving and cue reactivity in cocaine dependent humans
    Michael E Saladin
    Department of Health Sciences and Research, Medical University of South Carolina MUSC, Charleston, SC, USA
    Psychopharmacology (Berl) 226:721-37. 2013
    ..Secondarily, it was expected that group differences identified in the test session would be evident at a 1-week follow-up CCE session. Exploratory analyses of treatment effects on cocaine use were also performed at follow-up...
  31. ncbi Sertraline in the treatment of co-occurring alcohol dependence and posttraumatic stress disorder
    Kathleen T Brady
    The Medical University of South Carolina, Department of Psychiatry, Charleston, SC 29425, USA
    Alcohol Clin Exp Res 29:395-401. 2005
    ..Posttraumatic stress disorder (PTSD) frequently co-occurs with alcohol use disorders. This study investigated the use of sertraline, a serotonin reuptake inhibitor, in treating co-occurring symptoms of alcohol dependence and PTSD...
  32. doi A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report
    Bryan K Tolliver
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Bipolar Disord 14:54-63. 2012
    ..The current study assessed the effects of acamprosate on alcohol use and mood symptoms in subjects with co-occurring bipolar disorder and active alcohol dependence...
  33. pmc Early life trauma and sensitivity to current life stressors in individuals with and without cocaine dependence
    Sudie E Back
    Division of Clinical Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 34:389-96. 2008
    ..Adverse childhood events may lead to an altered view of the environment that contributes to increased irritability with daily life events among cocaine-dependent individuals...
  34. pmc Sustained reduction of nicotine craving with real-time neurofeedback: exploring the role of severity of dependence
    Melanie Canterberry
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC
    Nicotine Tob Res 15:2120-4. 2013
    ..The current study examined the role of nicotine-dependence severity and the efficacy of multiple visits of neurofeedback from a single region of interest (ROI) in the anterior cingulate cortex (ACC) on craving reduction...
  35. pmc Stress- and cue-elicited craving and reactivity in marijuana-dependent individuals
    Aimee L McRae-Clark
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    Psychopharmacology (Berl) 218:49-58. 2011
    ..Cue-elicited craving and stress responses have been identified as predictors of relapse in drug dependence, but little research exists on the contribution of these factors to marijuana use specifically...
  36. pmc D-cycloserine and cocaine cue reactivity: preliminary findings
    Kimber L Price
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, Charleston, SC 29425, USA
    Am J Drug Alcohol Abuse 35:434-8. 2009
    ..D-cycloserine (DCS), a partial glutamate N-methyl-D-aspartic acid (NMDA) receptor agonist, enhances extinction of conditioned fear responding in rodents and facilitates exposure-based learning in humans with anxiety disorders...
  37. pmc Extinction of drug cue reactivity in methamphetamine-dependent individuals
    Kimber L Price
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
    Behav Res Ther 48:860-5. 2010
    ..These results indicate that extinction of drug cue conditioned responding occurs in methamphetamine-dependent individuals, offering promise for the development of extinction- based treatment strategies...
  38. pmc A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on craving in cocaine-dependent individuals
    Kimber L Price
    Department of Psychiatry and Behavioral Sciences, Division of Clinical Neuroscience, Medical University of South Carolina, 67 President Street MSC 861, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 226:739-46. 2013
    ..D-Cycloserine (DCS), a partial glutamate N-methyl-D-aspartate (NMDA) receptor agonist, enhances extinction of conditioned fear responding; preliminary data suggest that it may facilitate extinction of drug cue reactivity...
  39. pmc Individual variability in the locus of prefrontal craving for nicotine: implications for brain stimulation studies and treatments
    Colleen A Hanlon
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Drug Alcohol Depend 125:239-43. 2012
    ..This investigation aims to guide these studies by assessing individual variability in the location of peak cortical activity during cue-elicited craving...
  40. ncbi PTSD and the HPA axis: differences in response to the cold pressor task among individuals with child vs. adult trauma
    Elizabeth J Santa Ana
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Psychoneuroendocrinology 31:501-9. 2006
    ..The findings reveal differences in the neuroendocrine response to the CPT in individuals with PTSD compared to control subjects, and differences in PTSD subjects when examined by age of index trauma...
  41. doi Comorbid anxiety disorders and baseline medication regimens predict clinical outcomes in individuals with co-occurring bipolar disorder and alcohol dependence: Results of a randomized controlled trial
    James J Prisciandaro
    Medical University of South Carolina, Department of Psychiatry of Psychiatry and Behavioral Sciences, Clinical Neurosciences Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Psychiatry Res 188:361-5. 2011
    ..Conversely, lithium was associated with decreased alcohol craving and depressive symptoms. The findings from the present study suggest areas for future research in this population...
  42. pmc Psychoticism and neuroticism predict cocaine dependence and future cocaine use via different mechanisms
    James J Prisciandaro
    Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Charleston, SC 29425, USA
    Drug Alcohol Depend 116:80-5. 2011
    ..e., impulsivity, neuroticism) and problematic cocaine use. Reactivity to a pharmacological stressor as a potential mediator of the relationship between neuroticism and future cocaine use was also examined...
  43. pmc Daily stressor sensitivity, abuse effects, and cocaine use in cocaine dependence
    Angela E Waldrop
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, SC 29425, USA
    Addict Behav 32:3015-25. 2007
    ..Reactivity to cocaine cues was related to daily hassle sensitivity among women only. Limitations and implications of the findings are discussed...
  44. pmc Effect of oxytocin on craving and stress response in marijuana-dependent individuals: a pilot study
    Aimee L McRae-Clark
    Clinical Neuroscience Division, Department of Psychiatry, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 228:623-31. 2013
    ..Oxytocin is a hypothalamic neuropeptide that has been shown to moderate behavioral responding to stress as well as play a role in the neuroadaptations that occur as a consequence of long-term drug use...
  45. pmc Prospective associations between brain activation to cocaine and no-go cues and cocaine relapse
    James J Prisciandaro
    Medical University of South Carolina, Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, 67 President Street, Charleston, SC 29425, USA
    Drug Alcohol Depend 131:44-9. 2013
    ..The purpose of the present study was to use fMRI to investigate prospective associations between brain reactivity to cocaine and response inhibition cues and relapse to cocaine use...
  46. ncbi Cognitive-behavioral stress management for individuals with substance use disorders: a pilot study
    Sudie E Back
    Division of Clinical Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Nerv Ment Dis 195:662-8. 2007
    ..Although preliminary, the findings suggest that systematic investigation of interventions specifically targeting stress management in individuals with substance use disorders should be undertaken...
  47. ncbi Pharmacotherapy of comorbid mood, anxiety, and substance use disorders
    Kathleen T Brady
    Institute of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Subst Use Misuse 40:2021-41, 2043-8. 2005
    ..Some of the barriers to the use of pharmacotherapy in individuals with substance use disorders are discussed...
  48. pmc Prescription opioid aberrant behaviors: a pilot study of sex differences
    Sudie E Back
    Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Medical University of South Carolina, Charleston, SC 29425, USA
    Clin J Pain 25:477-84. 2009
    ..Little is known about the sex differences in specific types of aberrant behaviors or sex-specific predictors of such behaviors. The current study is aimed to begin addressing this gap in the literature...
  49. pmc Gender differences in the effect of early life trauma on hypothalamic-pituitary-adrenal axis functioning
    Stacia M DeSantis
    Department of Medicine, Division of Biostatistics and Epidemiology, Medical University of South Carolina, 135 Cannon Street, Charleston, SC 29425, USA
    Depress Anxiety 28:383-92. 2011
    ..Individuals with major depressive disorder, posttraumatic stress disorder, bipolar disorder, or psychotic or eating disorders were excluded...
  50. pmc Right anterior insula connectivity is important for cue-induced craving in nicotine-dependent smokers
    Megan M Moran-Santa Maria
    Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Medical University of South Carolina, Charleston, SC, USA
    Addict Biol 20:407-14. 2015
    ..Moreover, treatment strategies that incorporate mindful attention may be effective in attenuating cue-induced craving and relapse in nicotine-dependent smokers. ..
  51. pmc Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies
    Huiping Zhang
    Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 66:128-36. 2009
    ..The pro-opiomelanocortin gene (POMC) encodes several peptides important for endogenous opioidergic neurotransmission. We tested whether POMC genetic variation affects risk for substance dependence...
  52. ncbi Does comorbid anxiety or depression affect clinical outcomes in patients with post-traumatic stress disorder and alcohol use disorders?
    Lawrence A Labbate
    Mental Health Service, VA Medical Center, and Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, USA
    Compr Psychiatry 45:304-10. 2004
    ..Hence, contrary to our hypothesis, having additional anxiety or mood disorder comorbidity did not decrease treatment response in individuals with comorbid PTSD and an alcohol use disorder...
  53. pmc A placebo-controlled trial of atomoxetine in marijuana-dependent individuals with attention deficit hyperactivity disorder
    Aimee L McRae-Clark
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Addict 19:481-9. 2010
    ..These results suggest that atomoxetine may improve some ADHD symptoms but does not reduce marijuana use in this population. ..
  54. ncbi Treatment of patients comorbid for addiction and other psychiatric disorders
    Kathleen T Brady
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Curr Psychiatry Rep 9:374-80. 2007
    ..Current treatment options and implications for future research are highlighted...
  55. pmc Some considerations for excess zeroes in substance abuse research
    Dipankar Bandyopadhyay
    Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Am J Drug Alcohol Abuse 37:376-82. 2011
    ..However, there is a need to consider the design aspects of those studies before using such a statistical model to ascertain the sources of zeroes...
  56. pmc Neural correlates of craving and resisting craving for tobacco in nicotine dependent smokers
    Karen J Hartwell
    Medical University of South Carolina, Charleston, 29425, USA
    Addict Biol 16:654-66. 2011
    ..Different strategies for resisting, such as distraction, activated different regions. Understanding the underlying neurobiology of resisting craving to smoke may identify new foci for treatments...
  57. pmc Non-treatment laboratory stress- and cue-reactivity studies are associated with decreased substance use among drug-dependent individuals
    Stacia M DeSantis
    Department of Biostatistics, Bioinformatics, and Epidemiology, 135 Cannon Street Suite 303, Charleston, SC 29425, USA
    Drug Alcohol Depend 105:227-33. 2009
    ..This study examines whether participation in such studies alters drug-seeking behavior and which patient attributes contribute to increased use...
  58. pmc Mood disorders and substance use disorder: a complex comorbidity
    Susan B Quello
    Medical University of South Carolina, Charleston, SC 29425, USA
    Sci Pract Perspect 3:13-21. 2005
    ..Expanded communication and collaboration between substance abuse and mental health providers is crucial to improving outcomes for patients with these complex, difficult co-occurring disorders...
  59. ncbi Alcohol use and anxiety: diagnostic and management issues
    Kathleen T Brady
    Medical University of South Carolina, Department of Psychiatry, 67 President St, PO Box 250861, Charleston, SC 29425, USA
    Am J Psychiatry 164:217-21; quiz 372. 2007
  60. ncbi Comparison of nefazodone and sertraline for the treatment of posttraumatic stress disorder
    Aimee L McRae
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Depress Anxiety 19:190-6. 2004
    ..This study did not find significant differences in the effectiveness of nefazodone and sertraline for the treatment of PTSD. Larger trials are warranted...
  61. ncbi Triggers for cocaine and alcohol use in the presence and absence of posttraumatic stress disorder
    Angela E Waldrop
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Box 250861, Charleston, SC 29425, USA
    Addict Behav 32:634-9. 2007
    ..The findings highlight the importance of addressing individual-specific high-risk situations in relapse prevention...
  62. doi Frequency and severity of comorbid mood and anxiety disorders in prescription opioid dependence
    Daniel F Gros
    Ralph H Johnson Veterans Affairs Medical Center, Medical University of South Carolina, Charleston, SC 29401, USA
    Am J Addict 22:261-5. 2013
    ..To address this gap in the literature, the present cross-sectional study investigated the clinical profiles of individuals with prescription opioid dependence with or without comorbid mood and anxiety disorders...
  63. pmc Sleep disturbances associated with posttraumatic stress disorder and alcohol dependence
    Angela E Waldrop
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Addict Behav 33:328-35. 2008
    ..These findings suggest a need for thorough assessment of sleep symptoms in patients presenting with PTSD or alcohol dependence...
  64. pmc Contingency management in community programs treating adolescent substance abuse: a feasibility study
    Therese K Killeen
    College of Medicine, Institute of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA
    J Child Adolesc Psychiatr Nurs 25:33-41. 2012
    ..Adolescent substance abuse remains a public health problem, and more effective treatment approaches are needed...