Research Topics

Marie Christine Boutron Ruault



  1. van Roekel E, Trijsburg L, Assi N, Carayol M, Achaintre D, Murphy N, et al. Circulating Metabolites Associated with Alcohol Intake in the European Prospective Investigation into Cancer and Nutrition Cohort. Nutrients. 2018;10: pubmed publisher
    ..This provides further leads for future research studies aiming at elucidating the mechanisms underlying the effects of alcohol in relation to morbid conditions. ..
  2. Savoye I, Jegou D, Kvaskoff M, Rommens K, Boutron Ruault M, Coppieters Y, et al. Is melanoma survival influenced by month of diagnosis?. Cancer Epidemiol. 2015;39:727-33 pubmed publisher
    ..Our findings do not support an influence of season of diagnosis on melanoma prognosis. ..
  3. Bastide N, Morois S, Cadeau C, Kangas S, Serafini M, Gusto G, et al. Heme Iron Intake, Dietary Antioxidant Capacity, and Risk of Colorectal Adenomas in a Large Cohort Study of French Women. Cancer Epidemiol Biomarkers Prev. 2016;25:640-7 pubmed publisher
    ..These results emphasize the need for a global assessment of diet when considering nutritional prevention of colorectal carcinogenesis. Cancer Epidemiol Biomarkers Prev; 25(4); 640-7. ©2016 AACR. ..
  4. Bastide N, Dartois L, Dyevre V, Dossus L, Fagherazzi G, Serafini M, et al. Dietary antioxidant capacity and all-cause and cause-specific mortality in the E3N/EPIC cohort study. Eur J Nutr. 2017;56:1233-1243 pubmed publisher
    ..This prospective cohort study highlights the importance of antioxidant consumption for mortality prevention, especially among current smokers. ..
  5. Cadeau C, Fournier A, Mesrine S, Clavel Chapelon F, Fagherazzi G, Boutron Ruault M. Vitamin C supplement intake and postmenopausal breast cancer risk: interaction with dietary vitamin C. Am J Clin Nutr. 2016;104:228-34 pubmed publisher
    ..Our data suggest a potential U- or J-shaped relation between total vitamin C intake and postmenopausal breast cancer risk that deserves further investigation. ..
  6. Cadeau C, Fournier A, Mesrine S, Clavel Chapelon F, Fagherazzi G, Boutron Ruault M. Interaction between current vitamin D supplementation and menopausal hormone therapy use on breast cancer risk: evidence from the E3N cohort. Am J Clin Nutr. 2015;102:966-73 pubmed publisher
    ..These findings should be confirmed before considering vitamin D supplementation to partly balance the MHT-associated increased breast cancer risk. ..
  7. Lajous M, Rossignol E, Fagherazzi G, Perquier F, Scalbert A, Clavel Chapelon F, et al. Flavonoid intake and incident hypertension in women. Am J Clin Nutr. 2016;103:1091-8 pubmed publisher
    ..In this large prospective cohort of French middle-aged women, participants with greater flavonol, anthocyanin, and polymeric flavonoid intakes and greater total flavonoid intake were less likely to develop hypertension. ..
  8. Cadeau C, Fournier A, Mesrine S, Clavel Chapelon F, Fagherazzi G, Boutron Ruault M. Postmenopausal breast cancer risk and interactions between body mass index, menopausal hormone therapy use, and vitamin D supplementation: Evidence from the E3N cohort. Int J Cancer. 2016;139:2193-200 pubmed publisher
    ..e. non-overweight MHT-non users, especially in the present context of increasing vitamin D supplement use and decreasing MHT use. ..
  9. Faure E, Danjou A, Clavel Chapelon F, Boutron Ruault M, Dossus L, Fervers B. Accuracy of two geocoding methods for geographic information system-based exposure assessment in epidemiological studies. Environ Health. 2017;16:15 pubmed publisher
    ..Accuracy of the two automatic geocoding methods was comparable. The in-house method (B) allowed a better control of the geocoding process and was less time consuming. ..

More Information


  1. Noh H, Freisling H, Assi N, Zamora Ros R, Achaintre D, Affret A, et al. Identification of Urinary Polyphenol Metabolite Patterns Associated with Polyphenol-Rich Food Intake in Adults from Four European Countries. Nutrients. 2017;9: pubmed publisher
    ..This proposed strategy of biomarker pattern identification has the potential of expanding the currently still limited list of available dietary intake biomarkers. ..
  2. Affret A, Wagner S, El Fatouhi D, Dow C, Correia E, Niravong M, et al. Validity and reproducibility of a short food frequency questionnaire among patients with chronic kidney disease. BMC Nephrol. 2017;18:297 pubmed publisher
    ..It may also serve as a basis for the development of FFQs in international CKD cohort networks. ..
  3. Chanoine S, Pin I, Sanchez M, Temam S, Pison C, Le Moual N, et al. Asthma Medication Ratio Phenotypes in Elderly Women. J Allergy Clin Immunol Pract. 2018;6:897-906.e5 pubmed publisher
    ..The level and the long-term fluctuations of the controller-to-total asthma medication ratio predict poor asthma-related outcomes in elderly women. ..
  4. Mancini F, Affret A, Dow C, Balkau B, Bonnet F, Boutron Ruault M, et al. Dietary antioxidant capacity and risk of type 2 diabetes in the large prospective E3N-EPIC cohort. Diabetologia. 2018;61:308-316 pubmed publisher
    ..More studies are warranted to better understand the biological mechanisms underlying this inverse association. ..