Alex Bottle

Summary

Publications

  1. pmc Hospital standardized mortality ratios: sensitivity analyses on the impact of coding
    Alex Bottle
    Department of Primary Care and PublicHealth, Imperial College London, 12 Smithfield St, London EC1A 9LA, UK
    Health Serv Res 46:1741-61. 2011
  2. doi Impact of transfer for angioplasty and distance on AMI in-hospital mortality
    Roxana Alexandrescu
    Dr Foster Unit at Imperial College, Department of Primary Care and Public Health, School of Public Health, Imperial College London, UK
    Acute Card Care 14:5-12. 2012
  3. ncbi Provider profiling models for acute coronary syndrome mortality using administrative data
    Alex Bottle
    Dr Foster Unit at Imperial, School of Public Health, Imperial College London, London, UK
    Int J Cardiol 168:338-43. 2013
  4. doi Significantly increasing hospital admissions for acute throat infections among children in England: is this related to tonsillectomy rates?
    Elizabeth Koshy
    Department of Primary Care and Public Health, Imperial College London, St Dunstan s Rd, London, UK
    Arch Dis Child 97:1064-8. 2012
  5. doi Preoperative stroke and outcomes after coronary artery bypass graft surgery
    Alex Bottle
    School of Public Health, Imperial College London, UK
    Anesthesiology 118:885-93. 2013
  6. pmc Using routine data to monitor inequalities in an acute trust: a retrospective study
    Katharine M Langford
    School of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK
    BMC Health Serv Res 12:104. 2012
  7. doi Single measures of performance do not reflect overall institutional quality in colorectal cancer surgery
    Alex M Almoudaris
    Department of Surgery and Cancer, Imperial College London, St Mary s Hospital, Praed Street, London W21NY, UK
    Gut 62:423-9. 2013
  8. pmc Intelligent information: a national system for monitoring clinical performance
    Alex Bottle
    Dr Foster Unit at Imperial College, Department of Primary Care and Social Medicine, Imperial College London, First Floor, Jarvis House, 12 Smithfield Street, London EC1A 9LA, U K
    Health Serv Res 43:10-31. 2008
  9. pmc Use of administrative data or clinical databases as predictors of risk of death in hospital: comparison of models
    Paul Aylin
    Dr Foster Unit, Imperial College London, London EC1A 9LA
    BMJ 334:1044. 2007
  10. doi Comorbidity scores for administrative data benefited from adaptation to local coding and diagnostic practices
    Alex Bottle
    Dr Foster Unit, Department of Primary Care and Public Health, Imperial College London, 12 Smithfield Street, London EC1A 9LA, UK
    J Clin Epidemiol 64:1426-33. 2011

Detail Information

Publications36

  1. pmc Hospital standardized mortality ratios: sensitivity analyses on the impact of coding
    Alex Bottle
    Department of Primary Care and PublicHealth, Imperial College London, 12 Smithfield St, London EC1A 9LA, UK
    Health Serv Res 46:1741-61. 2011
    ..They have been criticized for being sensitive to issues such as clinical coding but on the basis of limited quantitative evidence...
  2. doi Impact of transfer for angioplasty and distance on AMI in-hospital mortality
    Roxana Alexandrescu
    Dr Foster Unit at Imperial College, Department of Primary Care and Public Health, School of Public Health, Imperial College London, UK
    Acute Card Care 14:5-12. 2012
    ..The aim of the study was to evaluate the impact of transfer status and distance on in-hospital mortality for acute myocardial infarction (AMI) patients undergoing angioplasty on the same or next day of hospital admission...
  3. ncbi Provider profiling models for acute coronary syndrome mortality using administrative data
    Alex Bottle
    Dr Foster Unit at Imperial, School of Public Health, Imperial College London, London, UK
    Int J Cardiol 168:338-43. 2013
    ..We assess the impact on risk model performance and hospital-level mortality rate ratios (SMRs) of three key issues: comorbidity measurement methods, inter-hospital transfers and post-discharge deaths...
  4. doi Significantly increasing hospital admissions for acute throat infections among children in England: is this related to tonsillectomy rates?
    Elizabeth Koshy
    Department of Primary Care and Public Health, Imperial College London, St Dunstan s Rd, London, UK
    Arch Dis Child 97:1064-8. 2012
    ..To examine trends in hospital admissions for acute throat infection (ATI) and peritonsillar abscess (PTA) alongside tonsillectomy trends in children...
  5. doi Preoperative stroke and outcomes after coronary artery bypass graft surgery
    Alex Bottle
    School of Public Health, Imperial College London, UK
    Anesthesiology 118:885-93. 2013
    ..The authors investigated the preoperative predictors of adverse outcomes in patients undergoing CABG, with a focus on the importance of the time interval between prior stroke and CABG...
  6. pmc Using routine data to monitor inequalities in an acute trust: a retrospective study
    Katharine M Langford
    School of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK
    BMC Health Serv Res 12:104. 2012
    ..However, there is no standard system for monitoring inequalities in the care provided by acute trusts. We explore the feasibility of monitoring inequalities within an acute trust using routine data...
  7. doi Single measures of performance do not reflect overall institutional quality in colorectal cancer surgery
    Alex M Almoudaris
    Department of Surgery and Cancer, Imperial College London, St Mary s Hospital, Praed Street, London W21NY, UK
    Gut 62:423-9. 2013
    ..To evaluate overall performance of English colorectal cancer surgical units identified as outliers for a single quality measure--30 day inhospital mortality...
  8. pmc Intelligent information: a national system for monitoring clinical performance
    Alex Bottle
    Dr Foster Unit at Imperial College, Department of Primary Care and Social Medicine, Imperial College London, First Floor, Jarvis House, 12 Smithfield Street, London EC1A 9LA, U K
    Health Serv Res 43:10-31. 2008
    ..To use statistical process control charts to monitor in-hospital outcomes at the hospital level for a wide range of procedures and diagnoses...
  9. pmc Use of administrative data or clinical databases as predictors of risk of death in hospital: comparison of models
    Paul Aylin
    Dr Foster Unit, Imperial College London, London EC1A 9LA
    BMJ 334:1044. 2007
    ....
  10. doi Comorbidity scores for administrative data benefited from adaptation to local coding and diagnostic practices
    Alex Bottle
    Dr Foster Unit, Department of Primary Care and Public Health, Imperial College London, 12 Smithfield Street, London EC1A 9LA, UK
    J Clin Epidemiol 64:1426-33. 2011
    ..Our objective was to compare the original Charlson index, a modified set of Charlson codes after advice from clinical coders, and a published modified Elixhauser index in predicting in-hospital mortality...
  11. doi The performance of automated case-mix adjustment regression model building methods in a health outcome prediction setting
    Min Hua Jen
    Dr Foster Unit at Imperial College, Department of Primary Care and Public Health, Imperial College London, London, W6 8RP, UK
    Health Care Manag Sci 14:267-78. 2011
    ....
  12. doi Quality of routine hospital birth records and the feasibility of their use for creating birth cohorts
    Joanna Murray
    Department of Primary Care and Public Health, Imperial College London, St Dunstan s Road, London W6 8RP, UK
    J Public Health (Oxf) 35:298-307. 2013
    ..Data from births in English National Health Service hospitals are collected in the Hospital Episode Statistics (HES) database but are of uncertain quality...
  13. ncbi Association of population and primary healthcare factors with hospital admission rates for chronic obstructive pulmonary disease in England: national cross-sectional study
    Amaia Calderón-Larrañaga
    Department of Primary Care and Public Health, Imperial College London, 3rd Floor, Reynolds Building, Charing Cross Campus, Imperial College London, London, UK
    Thorax 66:191-6. 2011
    ..Hospital admission rates for chronic obstructive pulmonary disease (COPD) are known to be strongly associated with population factors. Primary care services may also affect admission rates, but there is little direct supporting evidence...
  14. pmc Nationwide study on trends in hospital admissions for major cardiovascular events and procedures among people with and without diabetes in England, 2004-2009
    Eszter P Vamos
    Department of Primary Care and Public Health, Imperial College London, London, UK
    Diabetes Care 35:265-72. 2012
    ....
  15. doi Independent preoperative predictors of outcomes in orthopedic and vascular surgery: the influence of time interval between an acute coronary syndrome or stroke and the operation
    Robert D Sanders
    Magill Department of Anaesthetics, Intensive Care and Pain Medicine, Imperial College London, Chelsea and Westminster Hospital, London, UK
    Ann Surg 255:901-7. 2012
    ....
  16. doi Logistic versus hierarchical modeling: an analysis of a statewide inpatient sample
    Roxana Alexandrescu
    Dr Foster Unit at Imperial College, Department of Primary Care and Public Health, Imperial College London, London, UK
    J Am Coll Surg 213:392-401. 2011
    ..Hierarchical models allow examination of the effect of data clustering on outcomes...
  17. doi The volume-outcome relationship for radical cystectomy in England: an analysis of outcomes other than mortality
    Erik K Mayer
    Department of Surgery and Cancer, 10th Floor QEQM Building, St Mary s Hospital Campus, Imperial College London, London W2 1NY, UK
    BJU Int 108:E258-65. 2011
    ..To evaluate the volume-outcome relationship for radical cystectomy in England using outcomes other than mortality...
  18. pmc Changes in the incidence of lower extremity amputations in individuals with and without diabetes in England between 2004 and 2008
    Eszter P Vamos
    Department of Primary Care and Public Health, Imperial College London, London, UK
    Diabetes Care 33:2592-7. 2010
    ..To describe recent trends in the incidence of nontraumatic amputations among individuals with and without diabetes and estimate the relative risk of amputations among individuals with diabetes in England...
  19. doi Towards a scientific workflow methodology for primary care database studies
    Vasa Curcin
    Department of Computing, Imperial College London, London SW7 2AZ, UK
    Stat Methods Med Res 19:378-93. 2010
    ....
  20. doi Admission rates and in-hospital mortality for hip fractures in England 1998 to 2009: time trends study
    Tai Yin Wu
    Department of Primary Care and Public Health, Imperial College London, Charing Cross Campus, London W6 8RP, UK
    J Public Health (Oxf) 33:284-91. 2011
    ..Fractures of the proximal femur are an important public health concern. The incidence of hip fractures is an index of osteoporosis burden. There have been no recent studies examining national trends in hip fractures in England...
  21. pmc Association between quality of primary care and hospitalization for coronary heart disease in England: national cross-sectional study
    Alex Bottle
    Dr Foster Unit, Department of Primary Care and Social Medicine, Imperial College London, London, UK
    J Gen Intern Med 23:135-41. 2008
    ..A new pay-for-performance scheme for primary care physicians was introduced in England in 2004 as part of an initiative to link the quality of primary care with physician pay...
  22. pmc Meeting the ambition of measuring the quality of hospitals' stroke care using routinely collected administrative data: a feasibility study
    William L Palmer
    Dr Foster Unit, Department of Primary Care and Social Medicine, Imperial College London, London, UK
    Int J Qual Health Care 25:429-36. 2013
    ..To examine the potential for using routinely collected administrative data to compare the quality and safety of stroke care at a hospital level, including evaluating any bias due to variations in coding practice...
  23. doi Staff perceptions of quality of care: an observational study of the NHS Staff Survey in hospitals in England
    Richard J Pinder
    Department of Primary Care and Public Health, Imperial College London, London, UK
    BMJ Qual Saf 22:563-70. 2013
    ..This study aimed to assess the potential of staff satisfaction to be used as an indicator of institutional performance across all acute National Health Service (NHS) hospitals in England...
  24. doi What is the role of risk-adjusted funnel plots in the analysis of radical cystectomy volume-outcome relationships?
    Erik K Mayer
    Division of Surgery, Department of Surgery and Cancer, Imperial College London, London, UK
    BJU Int 108:844-50. 2011
    ....
  25. doi Impact of the seven-valent pneumococcal conjugate vaccination (PCV7) programme on childhood hospital admissions for bacterial pneumonia and empyema in England: national time-trends study, 1997-2008
    Elizabeth Koshy
    Department of Primary Care and Public Health, Reynolds Building, Imperial College London, Charing Cross Campus, London W6 8RP, UK
    Thorax 65:770-4. 2010
    ..The aim of this study was to report national time trends in hospital admissions for childhood bacterial pneumonia and empyema in England before and after the introduction of PCV7...
  26. doi Blood pressure monitoring and control by cardiovascular disease status in UK primary care: 10 year retrospective cohort study 1998-2007
    Anthony A Laverty
    Department of Primary Care and Public Health, Imperial College London, St Dunstan s Road, London W6 8RP, UK
    J Public Health (Oxf) 33:302-9. 2011
    ..Strategies to reduce the burden of cardiovascular disease (CVD) in the UK have emphasized improved management of high-risk individuals rather than population-based approaches...
  27. ncbi Classifying hospitals as mortality outliers: logistic versus hierarchical logistic models
    Roxana Alexandrescu
    Dr Foster Unit at Imperial College, Department of Primary Care and Public Health, Imperial College London, London, EC4Y 8EN, UK
    J Med Syst 38:29. 2014
    ..The choice of methodological approach should, however, also consider whether the modelling aim is judgment or improvement, as shrinkage may be more appropriate for the former than the latter...
  28. doi Current ICD10 codes are insufficient to clearly distinguish acute myocardial infarction type: a descriptive study
    Roxana Alexandrescu
    Dr, Foster Unit at Imperial College, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London EC1A 9LA, UK
    BMC Health Serv Res 13:468. 2013
    ..The aim of the paper was to determine the feasibility of distinguishing AMI type, either ST elevation myocardial infarction (STEMI) or non-ST elevation myocardial infarction (NSTEMI), using ICD10 codes...
  29. doi Systematic review of comorbidity indices for administrative data
    Mansour T A Sharabiani
    Dr Foster Unit, Department of Primary Care and Public Health, School of Public Health, Imperial College London, London, UK
    Med Care 50:1109-18. 2012
    ....
  30. pmc Increasing skin infections and Staphylococcus aureus complications in children, England, 1997-2006
    Sonia Saxena
    Imperial College London, London, UK
    Emerg Infect Dis 16:530-3. 2010
    ..8 to 29.1/1,000 child-years. During the same time period, hospital admissions for Staphylococcus aureus infections rose 49% from 53.4 to 79.3/100,000 child-years...
  31. doi Trends in lower extremity amputations in people with and without diabetes in England, 1996-2005
    Eszter Panna Vamos
    Department of Primary Care and Public Health, Imperial College London, UK
    Diabetes Res Clin Pract 87:275-82. 2010
    ..To examine trends in non-traumatic lower extremity amputations over a 10-year-period in people with and without diabetes (DM) in England...
  32. pmc Adverse events recorded in English primary care: observational study using the General Practice Research Database
    Carmen Tsang
    Dr Foster Unit at Imperial, Department of Primary Care and Public Health, Imperial College London, London
    Br J Gen Pract 63:e534-42. 2013
    ..More accurate and recent estimates of adverse events in primary care are necessary to assign resources for improvement of patient safety, while predictors must be identified to ameliorate patient risk...
  33. pmc Identifying patients at high risk of emergency hospital admissions: a logistic regression analysis
    Alex Bottle
    Department of Primary Care and Social Medicine, Imperial College London, London W6 8RP, UK
    J R Soc Med 99:406-14. 2006
    ..To use routine data to identify patients at high risk of future emergency hospital admissions...
  34. doi Examining the 'gold standard': a comparative critical analysis of three consecutive decades of monopolar transurethral resection of the prostate (TURP) outcomes
    Erik K Mayer
    Department of Urology, St Mary s Hospital, Imperial College Healthcare NHS Trust, London, UK
    BJU Int 110:1595-601. 2012
    ..Delaying surgery by prolonged medical monotherapy may compound this. Trials methodology in this area requires quality improvement and standardisation in future...
  35. ncbi Variations in vaginal and abdominal hysterectomy by region and trust in England
    Alex Bottle
    Dr Foster Unit at Imperial, Department of Epidemiology and Piblic Health, Imperial College London, London W2 1PG, UK
    BJOG 112:326-8. 2005
    ..To examine variations between regions and hospitals in the proportion of hysterectomies performed abdominally...
  36. ncbi Following Shipman: a pilot system for monitoring mortality rates in primary care
    Paul Aylin
    Department of Epidemiology and Public Health, Imperial College London, St Mary s Campus, Norfolk Place, W2 1PF, London, UK
    Lancet 362:485-91. 2003
    ..If used appropriately, such charts represent a useful tool for monitoring deaths in primary care. However, improvement in data quality is essential...