C J Boos

Summary

Publications

  1. ncbi request reprint Danazol treatment and acute myocardial infarction
    C J Boos
    Department of Cardiology, St Mary s Hospital, Portsmouth, UK
    J Obstet Gynaecol 23:327-8. 2003
  2. doi request reprint The effects of exercise at high altitude on high-sensitivity cardiac troponin release and associated biventricular cardiac function
    Christopher John Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Longfleet Rd Poole, Dorset, BH15 2JB, UK
    Clin Res Cardiol 103:291-9. 2014
  3. doi request reprint The effects of prolonged acute hypobaric hypoxia on novel measures of biventricular performance
    Christopher J Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Dorset, United Kingdom
    Echocardiography 30:534-41. 2013
  4. doi request reprint The effects of acute hypobaric hypoxia on arterial stiffness and endothelial function and its relationship to changes in pulmonary artery pressure and left ventricular diastolic function
    C J Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Longfleet Road, Poole, Dorset BH15 2JB, United Kingdom
    High Alt Med Biol 13:105-11. 2012
  5. ncbi request reprint Cardiology
    C J Boos
    Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, UK
    J R Army Med Corps 156:172-5. 2010
  6. ncbi request reprint Dietary supplements and military operations: caution is advised
    C J Boos
    MDHU Portsmouth, Queen Alexandra Hospital, Cosham PO6 3LY
    J R Army Med Corps 156:41-3. 2010
  7. ncbi request reprint Cardiovascular protection with ace inhibitors--more HOPE for EUROPA?
    Christopher J Boos
    Department of Cardiology, Southampton General Hospital, Southampton, UK
    Med Sci Monit 10:SR23-8. 2004
  8. ncbi request reprint Novel therapies for the prevention of stroke
    Christopher J Boos
    Southampton General Hospital, Department of Cardiology, UK
    Expert Opin Investig Drugs 13:1615-30. 2004
  9. ncbi request reprint Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: from pathophysiology to clinical trials
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Hum Hypertens 19:855-9. 2005
  10. doi request reprint An unusual case of misdiagnosed ventricular tachycardia
    C J Boos
    Department of Cardiology, University Hospital Birmingham, Edgbaston, Birmingham, B15 2TH, UK
    Emerg Med J 25:173-4. 2008

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Danazol treatment and acute myocardial infarction
    C J Boos
    Department of Cardiology, St Mary s Hospital, Portsmouth, UK
    J Obstet Gynaecol 23:327-8. 2003
  2. doi request reprint The effects of exercise at high altitude on high-sensitivity cardiac troponin release and associated biventricular cardiac function
    Christopher John Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Longfleet Rd Poole, Dorset, BH15 2JB, UK
    Clin Res Cardiol 103:291-9. 2014
    ..This study assessed the effects of exercise at progressively increasing HA on high-sensitivity (hs)-cTnT levels and their relationship to biventricular cardiac function and severity of acute mountain sickness (AMS)...
  3. doi request reprint The effects of prolonged acute hypobaric hypoxia on novel measures of biventricular performance
    Christopher J Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Dorset, United Kingdom
    Echocardiography 30:534-41. 2013
    ..There are limited data on the effects of prolonged acute hypoxia on individual and global measures of biventricular function...
  4. doi request reprint The effects of acute hypobaric hypoxia on arterial stiffness and endothelial function and its relationship to changes in pulmonary artery pressure and left ventricular diastolic function
    C J Boos
    Department of Cardiology, Poole Hospital NHS Foundation Trust, Longfleet Road, Poole, Dorset BH15 2JB, United Kingdom
    High Alt Med Biol 13:105-11. 2012
    ..However, the degree of hypoxia influences both the systemic endothelial and pulmonary vascular responses. This noted association is intriguing and requires further investigation...
  5. ncbi request reprint Cardiology
    C J Boos
    Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, UK
    J R Army Med Corps 156:172-5. 2010
    ..Cardiac disease remains a significant threat to both local and deployed military populations. In this article we present several cardiac case reports which may be of educational use to the military clinician...
  6. ncbi request reprint Dietary supplements and military operations: caution is advised
    C J Boos
    MDHU Portsmouth, Queen Alexandra Hospital, Cosham PO6 3LY
    J R Army Med Corps 156:41-3. 2010
    ..This has important implications for both serving soldiers and the wider medical community...
  7. ncbi request reprint Cardiovascular protection with ace inhibitors--more HOPE for EUROPA?
    Christopher J Boos
    Department of Cardiology, Southampton General Hospital, Southampton, UK
    Med Sci Monit 10:SR23-8. 2004
    ..In addition, they have been shown to slow the progression of chronic kidney disease and reduce the recurrence of stroke and vascular events...
  8. ncbi request reprint Novel therapies for the prevention of stroke
    Christopher J Boos
    Southampton General Hospital, Department of Cardiology, UK
    Expert Opin Investig Drugs 13:1615-30. 2004
    ..Finally, a controversial novel polypill, which would include fixed combinations of several pharmacological agents, may yet become a realistic and promising stroke prevention option...
  9. ncbi request reprint Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: from pathophysiology to clinical trials
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Hum Hypertens 19:855-9. 2005
  10. doi request reprint An unusual case of misdiagnosed ventricular tachycardia
    C J Boos
    Department of Cardiology, University Hospital Birmingham, Edgbaston, Birmingham, B15 2TH, UK
    Emerg Med J 25:173-4. 2008
    ..However, later analysis of his ECGs revealed that the apparent VT was, in fact, an artefact related to his parkinsonian tremor...
  11. ncbi request reprint Endotoxemia, inflammation, and atrial fibrillation
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
    Am J Cardiol 100:986-8. 2007
    ..In conclusion, experimental LPS challenge led to a significant increase in acute inflammatory indexes, but did not increase the propensity to new-onset AF in a young low-risk population...
  12. pmc An unusual case of chronic meningitis
    Christopher Boos
    Department of General Medicine, Portsmouth Hospitals NHS Trust, Milton Rd, Portsmouth, UK
    BMC Fam Pract 5:21. 2004
    ..Chronic meningitis is defined as symptoms and signs of meningeal inflammation and persisting cerebrospinal fluid abnormalities such as elevated protein level and pleocytosis for at least one month...
  13. ncbi request reprint Effects of transvenous pacing on cardiac troponin release
    Christopher J Boos
    Department of Cardiology, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom
    Pacing Clin Electrophysiol 27:1264-8. 2004
    ..39 +/- 0.37 microg/L, normal < 0.15 microg/L). The only factor that correlated with this rise was prolonged x ray screening time for lead implantation...
  14. pmc Fever six weeks after trauma
    C J Boos
    Department of Cardiology, St Mary s Hospital, Portsmouth PO3 6AD, UK
    J R Soc Med 96:187-8. 2003
  15. ncbi request reprint Higher energy monophasic DC cardioversion for persistent atrial fibrillation: is it time to start at 360 joules?
    C Boos
    St Mary s Hospital, Milton Road, Portsmouth, PO3 6AD, UK
    Ann Noninvasive Electrocardiol 8:121-6. 2003
    ....
  16. ncbi request reprint Rate or rhythm control in persistent atrial fibrillation?
    C J Boos
    Department of Cardiology, Portsmouth Hospitals NHS Trust, Portsmouth, UK
    QJM 96:881-92. 2003
    ..We draw conclusions from these studies and present evidence-based guidance on when to adopt which approach in routine clinical practice...
  17. ncbi request reprint Self-administration of exercise and dietary supplements in deployed British military personnel during Operation TELIC 13
    C J Boos
    MDHU Portsmouth
    J R Army Med Corps 156:32-6. 2010
    ..This study aimed to establish the point prevalence of dietary and exercise supplement usage in British soldiers on Op TELIC during January 2009...
  18. pmc Smoking rates in the staff of a military field hospital before and after wartime deployment
    C J Boos
    34 Field Hospital, Op TELIC, British Forces Post Office 647, UK
    J R Soc Med 97:20-2. 2004
    ..However, even the pre-existing rate of 42% in regular army personnel is high enough to demand urgent action by an employer...
  19. ncbi request reprint The use of exercise and dietary supplements among British soldiers in Afghanistan
    C J Boos
    MDHU Portsmouth, Cosham, Portsmouth, Hants
    J R Army Med Corps 157:229-32. 2011
    ..Consequently, an exploratory pilot study was undertaken to assess whether the findings of the previous Iraq study were applicable to current deployed British servicemen in Afghanistan...
  20. doi request reprint Antithrombotic treatment in atrial fibrillation
    G Y H Lip
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
    Postgrad Med J 84:252-8. 2008
    ..Stroke is the most serious complication. Evidence from AF antithrombotic treatment trials is reviewed, risk stratification of patients with AF is discussed, and recommendations for anticoagulation are presented...
  21. pmc Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer
    P K Y Goon
    Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England, UK
    Neoplasia 8:79-88. 2006
    ....
  22. doi request reprint The relationship of circulating endothelial cells to plasma indices of endothelial damage/dysfunction and apoptosis in acute coronary syndromes: implications for prognosis
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Thromb Haemost 6:1841-50. 2008
    ..While coronary artery disease has been linked to both endothelial damage and cellular apoptosis, their inter-relationships and impact on cardiovascular (CV) outcomes has been barely explored...
  23. ncbi request reprint Elevated high-sensitive C-reactive protein, large arterial stiffness and atherosclerosis: a relationship between inflammation and hypertension?
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Hum Hypertens 19:511-3. 2005
  24. ncbi request reprint Endothelial progenitor cells in the vascular pathophysiology of hypertension: arterial stiffness, ageing and more
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Hum Hypertens 20:475-7. 2006
  25. ncbi request reprint Total knee arthroplasty infection due to Abiotrophia defectiva
    A Ince
    Department of Orthopedics, Luebeck University Hospital, Germany
    J Med Microbiol 51:899-902. 2002
    ..The microbiology of this bacterium is discussed and clinical features of previously reported cases of infections by NVS are reviewed briefly...
  26. pmc Antithrombotic treatment in atrial fibrillation
    G Y H Lip
    University Department of Medicine, City Hospital, Birmingham, UK
    Heart 92:155-61. 2006
    ..In this article, the evidence for AF treatment trial of antithrombotic therapy is reviewed. Stroke risk stratification of patients with AF is discussed, and practical recommendations for thromboprophylaxis are presented...
  27. ncbi request reprint Platelet activation and cardiovascular outcomes in acute coronary syndromes
    C J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    J Thromb Haemost 4:2542-3. 2006
  28. ncbi request reprint Circulating endothelial cells: markers of vascular dysfunction
    P K Y Goon
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    Clin Lab 51:531-8. 2005
    ..In this article we present an overview of CECs and their association with a broad spectrum of disease processes...
  29. ncbi request reprint Back pain in a Bangladeshi worker in Iraq
    S H White
    Royal Centre for Defence Medicine, Birmingham, and Hospital Squadron, UK Medical Group, Op TELIC, BFPO 641
    J R Army Med Corps 156:44-6. 2010
    ..The patient was repatriated to Bangladesh for MRI and definitive surgical treatment...
  30. ncbi request reprint Is hypertension an inflammatory process?
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England, UK
    Curr Pharm Des 12:1623-35. 2006
    ..The inflammatory state in hypertension may pose a new therapeutic target for future drug design...
  31. pmc Management of atrial fibrillation
    Puneet Kakar
    Hemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    Vasc Health Risk Manag 3:109-16. 2007
    ....
  32. ncbi request reprint Inflammation and atrial fibrillation: cause or effect?
    Christopher J Boos
    Heart 94:133-4. 2008
  33. ncbi request reprint Blood clotting, inflammation, and thrombosis in cardiovascular events: perspectives
    Christopher J Boos
    University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
    Front Biosci 11:328-36. 2006
    ....
  34. ncbi request reprint Ximelagatran for stroke prevention in atrial fibrillation
    Christopher J Boos
    City Hospital, Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, Birmingham B18 7QH, UK
    Expert Rev Cardiovasc Ther 3:551-63. 2005
    ..Unfortunately, initial optimism has been tempered by serious concerns over its safety data in view of its propensity to cause elevation in liver enzymes...
  35. pmc Gastroenteritis outbreak in British troops, Iraq
    Mark S Bailey
    Army Medical Directorate, Camberley, UK
    Emerg Infect Dis 11:1625-8. 2005
    ..In a survey of 500 hospital staff, 76% reported gastroenteritis, which was more likely in clinical workers. Investigations showed only caliciviruses...
  36. ncbi request reprint The role of inflammation in atrial fibrillation
    Christopher J Boos
    Int J Clin Pract 59:870-2. 2005
  37. ncbi request reprint C-reactive protein and lone atrial fibrillation: potential confounders
    Christopher J Boos
    Am J Cardiol 98:991-2. 2006
  38. ncbi request reprint Biomarkers in atrial fibrillation: further observations on biologic plausibility, cause and effect
    Christopher J Boos
    J Thromb Thrombolysis 20:189-90. 2005
  39. ncbi request reprint ACE cardiovascular protection: EUROPA versus HOPE
    Christopher J Boos
    Cardiovasc Drugs Ther 18:179-80. 2004
  40. ncbi request reprint Prevention of atrial fibrillation by angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers
    Christopher J Boos
    J Am Coll Cardiol 47:889-90; author reply 890-1. 2006
  41. ncbi request reprint Is atrial fibrillation an inflammatory disorder?
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
    Eur Heart J 27:136-49. 2006
    ....
  42. pmc Persistent atrial fibrillation: rate control or rhythm control. Rate control is not inferior to rhythm control
    Christopher J Boos
    BMJ 326:1411-2. 2003
  43. ncbi request reprint Effects of percutaneous coronary intervention on peripheral venous blood circulating endothelial cells and plasma indices of endothelial damage/dysfunction
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, UK
    Chest 132:1920-6. 2007
    ....
  44. ncbi request reprint Relationship between C-reactive protein concentrations during glucocorticoid therapy and recurrent atrial fibrillation
    Christopher J Boos
    Eur Heart J 25:1761-2. 2004
  45. ncbi request reprint Assessment of endothelial damage/dysfunction: a focus on circulating endothelial cells
    Christopher J Boos
    Haemostasis Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, England, UK
    Methods Mol Med 139:211-24. 2007
    ..Increased CECs have been noted in a number of disease states and is evolving as a novel method of assessment of both disease severity and response to treatment...
  46. ncbi request reprint Oral anticoagulation and stroke in atrial fibrillation
    Christopher J Boos
    N Engl J Med 349:2360-1; author reply 2360-1. 2003
  47. ncbi request reprint Atrial fibrillation
    Christopher J Boos
    Cleve Clin J Med 70:998; author reply 998. 2003
  48. ncbi request reprint The effects of exercise stress testing on soluble E-selectin, von Willebrand factor, and circulating endothelial cells as indices of endothelial damage/dysfunction
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    Ann Med 40:66-73. 2008
    ..The quantification of circulating endothelial cells (CECs) in whole blood is an increasingly recognized index of endothelial damage/dysfunction. Abnormal CECs have been linked to the severity of coronary artery disease (CAD)...
  49. ncbi request reprint Circulating endothelial progenitor cells
    Christopher J Boos
    N Engl J Med 353:2613-6; author reply 2613-6. 2005
  50. ncbi request reprint The endothelium, inflammation, and coagulation in sepsis
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
    Clin Pharmacol Ther 79:20-2. 2006
  51. ncbi request reprint Assessment of hemostatic risk factors in predicting arterial thrombotic events
    Christopher J Boos
    Arterioscler Thromb Vasc Biol 26:e18. 2006
  52. ncbi request reprint Ethnic differences in arterial responses, inflammation, and metabolic profiles: possible insights into ethnic differences in cardiovascular disease and stroke
    Gregory Y H Lip
    Arterioscler Thromb Vasc Biol 25:2240-2. 2005
  53. ncbi request reprint Ximelagatran: an eulogy
    Christopher J Boos
    Thromb Res 118:301-4. 2006
  54. ncbi request reprint Urotensin and cardiovascular risk among patients with end-stage renal disease: fact or fiction?
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, England
    Am J Hypertens 19:511-2. 2006
  55. ncbi request reprint Anticoagulation control with vitamin K antagonists: how well are we doing?
    Deirdre A Lane
    Chest 129:1122-4. 2006
  56. ncbi request reprint Temporal and venepuncture-related decline in circulating endothelial cell capture from mixed venous blood
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK, B18 7QH
    J Thromb Thrombolysis 22:125-31. 2006
    ..We hypothesized that there is a temporal decline in CEC counts in static venesected blood and that venepuncture itself may lead to increased CEC detachment...
  57. ncbi request reprint Circulating endothelial cells in cardiovascular disease
    Christopher J Boos
    Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, United Kingdom
    J Am Coll Cardiol 48:1538-47. 2006
    ..This article presents an overview of the pathophysiology of CECs in the setting of cardiovascular disease and a brief comparison with EPCs...
  58. ncbi request reprint Assessment of platelet activation indices using the ADVIATM 120 amongst 'high-risk' patients with hypertension
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, UK
    Ann Med 39:72-8. 2007
    ....
  59. ncbi request reprint Relationship between circulating endothelial cells and the predicted risk of cardiovascular events in acute coronary syndromes
    Christopher J Boos
    Haemostasis, Thrombosis, and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH UK
    Eur Heart J 28:1092-101. 2007
    ..We hypothesized that there would be a significant relationship between increasing CEC counts and predicted CV risk in a broad spectrum of patients presenting with acute coronary syndrome (ACS)...
  60. ncbi request reprint The effects of coronary artery disease severity on time-dependent changes in platelet activation indices in stored whole blood
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham, B18 7QH, UK
    J Thromb Thrombolysis 25:135-40. 2008
    ..Whilst there has been some investigation into the effects of storage time on several of these indices, the effects of underlying disease severity on these temporal changes have not been previously studied...
  61. ncbi request reprint Uterine artery embolisation for massive uterine fibroids in the presence of submassive pulmonary emboli
    Christopher J Boos
    Department of Cardiology, Southampton General Hospital, Southampton, UK
    BJOG 112:1440-2. 2005
  62. ncbi request reprint Circulating endothelial cells, arterial stiffness, and cardiovascular risk stratification in hypertension
    Christopher J Boos
    Haemostasis, Thrombosis and Vascular Biology Unit, University Department of Medicine, City Hospital, Birmingham B18 7QH, England, UK
    Chest 132:1540-7. 2007
    ..Aims: To investigate the relationship between endothelial damage/dysfunction, arterial stiffness, and their association with predicted risk of future cardiovascular death among patients with hypertension...