Wendy B Bollag
Choudhary V, Olala L, Kaddour Djebbar I, Helwa I, Bollag W. Protein kinase D1 deficiency promotes differentiation in epidermal keratinocytes. J Dermatol Sci. 2014;76:186-95 pubmed publisher
..However, PKD1 loss had no effect on stem cell marker expression. Cre-recombinase-mediated knockdown represents an additional approach demonstrating that PKD1 is an anti-differentiative, pro-proliferative signal in mouse keratinocytes. ..
Olala L, Shapiro B, Merchen T, Wynn J, Bollag W. Protein kinase C and Src family kinases mediate angiotensin II-induced protein kinase D activation and acute aldosterone production. Mol Cell Endocrinol. 2014;392:173-81 pubmed publisher
..Taken together, our results demonstrate that AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production. ..
Choudhary V, Olala L, Qin H, Helwa I, Pan Z, Tsai Y, et al
. Aquaporin-3 re-expression induces differentiation in a phospholipase D2-dependent manner in aquaporin-3-knockout mouse keratinocytes. J Invest Dermatol. 2015;135:499-507 pubmed publisher
..Thus, our results indicate that AQP3 has a pro-differentiative role in epidermal keratinocytes and that PLD2 activity is necessary for this effect. ..