Ropinirole in the treatment of patients with restless legs syndrome: a US-based randomized, double-blind, placebo-controlled clinical trialRichard K Bogan
SleepMed of South Carolina, 1333 Taylor St, Columbia, SC 29201, USA
Mayo Clin Proc 81:17-27. 2006
..To assess the efficacy, safety, and tolerability of the dopamine agonist ropinirole in the treatment of patients with moderate to severe primary restless legs syndrome (RLS)...
Ropinirole treatment for restless legs syndromeRichard K Bogan
SleepMed of South Carolina, 1333 Taylor St, Suite 6B, Columbia, SC 29201, USA
Expert Opin Pharmacother 9:611-23. 2008
..Restless legs syndrome (RLS) is a chronic neurological disorder associated with sleep disturbance...
- Treatment options for insomnia--pharmacodynamics of zolpidem extended-release to benefit next-day performance
Richard K Bogan
SleepMed Inc, Columbia, SC 29201, USA
Postgrad Med 120:161-71. 2008
..A concern with insomnia medications is the risk of next-day residual effects, which can impair memory and ability to perform certain tasks, such as driving, and may increase the risk of accidents and falls, especially in the elderly...
- Armodafinil in the treatment of excessive sleepiness
Richard K Bogan
SleepMed, Inc, University of South Carolina School of Medicine, Columbia, SC 29201, USA
Expert Opin Pharmacother 11:993-1002. 2010
..It is the R-enantiomer of modafinil, which is a racemic mixture of R- and S-enantiomers...
Long-term maintenance treatment of restless legs syndrome with gabapentin enacarbil: a randomized controlled studyRichard K Bogan
SleepMed, Columbia, SC 2920, USA
Mayo Clin Proc 85:512-21. 2010
..To assess maintenance of efficacy and tolerability of gabapentin enacarbil in patients with moderate to severe primary restless legs syndrome (RLS)...
- No effect of 8-week time in bed restriction on glucose tolerance in older long sleepers
Mark R Zielinski
Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
J Sleep Res 17:412-9. 2008
..These results suggest that healthy older long sleepers can tolerate 8 weeks of moderate TIB restriction without impairments in glucose tolerance or insulin sensitivity...
- Tolerance of chronic 90-minute time-in-bed restriction in older long sleepers
Shawn D Youngstedt
Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA
Sleep 32:1467-79. 2009
..To examine the influence of chronic time-in-bed (TIB) restriction on selected health-related outcome variables in older long sleepers...
- Dosing regimen effects of modafinil for improving daytime wakefulness in patients with narcolepsy
Jonathan R L Schwartz
Integris Sleep Disorders Center of Oklahoma, Integris Southwest and Baptist Medical Centers, 4200 S Douglas Avenue, Suite 313, Oklahoma City, OK 73109, USA
Clin Neuropharmacol 26:252-7. 2003
..Some patients may benefit from 400-mg doses of modafinil taken once daily compared with 200-mg doses. A split-dose 400-mg regimen may be superior to once-daily dosing for sustaining wakefulness throughout the entire waking day...
- Dose effects of modafinil in sustaining wakefulness in narcolepsy patients with residual evening sleepiness
Jonathan R L Schwartz
Integris Sleep Disorders Center of Oklahoma, Integris Southwest and Baptist Medical Centers, 4200 S Douglas, Suite 313, Oklahoma City, OK 73109, USA
J Neuropsychiatry Clin Neurosci 17:405-12. 2005
..In patients who experience excessive sleepiness in the late afternoon/evening, despite satisfactory treatment earlier in the day, a split dose of modafinil may promote wakefulness throughout the waking day...
