Paolo Boffetta

Summary

Publications

  1. doi request reprint Epidemiologic studies of styrene and cancer: a review of the literature
    Paolo Boffetta
    International Prevention Research Institute, Lyon, France
    J Occup Environ Med 51:1275-87. 2009
  2. pmc Smoking water-pipe, chewing nass and prevalence of heart disease: a cross-sectional analysis of baseline data from the Golestan Cohort Study, Iran
    Farhad Islami
    One Gustave L Levy Place, New York, NY 10029, USA
    Heart 99:272-8. 2013
  3. pmc Estimation of cancer incidence and mortality attributable to alcohol drinking in China
    Hao Liang
    Department of Cancer Epidemiology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China
    BMC Public Health 10:730. 2010
  4. doi request reprint Acetaldehyde level in spirits from central European countries
    Paolo Boffetta
    International Prevention Research Institute, Lyon, France
    Eur J Cancer Prev 20:526-9. 2011
  5. doi request reprint Occupational exposure to arsenic, cadmium, chromium, lead and nickel, and renal cell carcinoma: a case-control study from Central and Eastern Europe
    Paolo Boffetta
    International Prevention Research Institute, 95 cours Lafayette, Lyon 69006, France
    Occup Environ Med 68:723-8. 2011
  6. doi request reprint Biomarkers in cancer epidemiology: an integrative approach
    Paolo Boffetta
    International Prevention Research Institute, 95 cours Lafayette, 69006 Lyon, France
    Carcinogenesis 31:121-6. 2010
  7. doi request reprint Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)
    Paolo Boffetta
    The Tisch Cancer Institute, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Cancer Causes Control 22:463-8. 2011
  8. pmc Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO)
    Paolo Boffetta
    The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY, USA
    Cancer Causes Control 22:73-9. 2011
  9. ncbi request reprint The association of sequence variants in DNA repair and cell cycle genes with cancers of the upper aerodigestive tract
    Janet Hall
    International Agency for Research on Cancer, Lyon, France
    Carcinogenesis 28:665-71. 2007
  10. doi request reprint Dietary risk factors for hypopharyngeal cancer in India
    Julia E Heck
    International Agency for Research on Cancer, Lyon, France
    Cancer Causes Control 19:1329-37. 2008

Detail Information

Publications89

  1. doi request reprint Epidemiologic studies of styrene and cancer: a review of the literature
    Paolo Boffetta
    International Prevention Research Institute, Lyon, France
    J Occup Environ Med 51:1275-87. 2009
    ..To review the epidemiologic literature on styrene and cancer...
  2. pmc Smoking water-pipe, chewing nass and prevalence of heart disease: a cross-sectional analysis of baseline data from the Golestan Cohort Study, Iran
    Farhad Islami
    One Gustave L Levy Place, New York, NY 10029, USA
    Heart 99:272-8. 2013
    ..Therefore, we investigated the association of smoking water-pipe and chewing nass (a mixture of tobacco, lime and ash) with prevalent HD...
  3. pmc Estimation of cancer incidence and mortality attributable to alcohol drinking in China
    Hao Liang
    Department of Cancer Epidemiology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China
    BMC Public Health 10:730. 2010
    ..Due to the current lack of data and the imperative need to guide policymakers on issues of cancer prevention and control, we aim to estimate the role of alcohol on the cancer burden in China in 2005...
  4. doi request reprint Acetaldehyde level in spirits from central European countries
    Paolo Boffetta
    International Prevention Research Institute, Lyon, France
    Eur J Cancer Prev 20:526-9. 2011
    ..The acetaldehyde level should be monitored and high-level exposure should be avoided...
  5. doi request reprint Occupational exposure to arsenic, cadmium, chromium, lead and nickel, and renal cell carcinoma: a case-control study from Central and Eastern Europe
    Paolo Boffetta
    International Prevention Research Institute, 95 cours Lafayette, Lyon 69006, France
    Occup Environ Med 68:723-8. 2011
    ..To investigate the risk of renal cell carcinoma (RCC) in Central and Eastern Europe in relation to exposure to known and suspected carcinogenic metals...
  6. doi request reprint Biomarkers in cancer epidemiology: an integrative approach
    Paolo Boffetta
    International Prevention Research Institute, 95 cours Lafayette, 69006 Lyon, France
    Carcinogenesis 31:121-6. 2010
    ..The overarching goal is the integration of different types of biomarkers to derive risk and outcome profiles for healthy individuals as well as patients...
  7. doi request reprint Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)
    Paolo Boffetta
    The Tisch Cancer Institute, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Cancer Causes Control 22:463-8. 2011
    ..An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report...
  8. pmc Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO)
    Paolo Boffetta
    The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY, USA
    Cancer Causes Control 22:73-9. 2011
    ..This framework offered the opportunity to investigate the role of tobacco smoking in the development of bronchioloalveolar carcinoma (BAC), a rare form of lung cancer...
  9. ncbi request reprint The association of sequence variants in DNA repair and cell cycle genes with cancers of the upper aerodigestive tract
    Janet Hall
    International Agency for Research on Cancer, Lyon, France
    Carcinogenesis 28:665-71. 2007
    ..While some of these associations are consistent with previous studies, we cannot rule out the possibility of false-positive associations. The positive findings should be explored in another large-scale study on UADT cancers...
  10. doi request reprint Dietary risk factors for hypopharyngeal cancer in India
    Julia E Heck
    International Agency for Research on Cancer, Lyon, France
    Cancer Causes Control 19:1329-37. 2008
    ..The Indian subcontinent has among the highest rates of hypopharyngeal cancer worldwide. The purpose of this study was to examine the associations between the Indian diet and hypopharyngeal cancer...
  11. ncbi request reprint Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study
    Rayjean J Hung
    International Agency for Research on Cancer, Lyon, France
    J Natl Cancer Inst 97:567-76. 2005
    ..We examined associations among four well-characterized polymorphisms of BER genes (OGG1 Ser326Cys, XRCC1 Arg194Trp, XRCC1 Arg280His, and XRCC1 Arg399Gln) and lung cancer risk...
  12. ncbi request reprint Cancer mortality among European asphalt workers: an international epidemiological study. II. Exposure to bitumen fume and other agents
    Paolo Boffetta
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Am J Ind Med 43:28-39. 2003
    ..An increased risk of lung cancers among asphalt workers has been suggested in epidemiological studies based on large scale statistical analyses...
  13. ncbi request reprint Occupational exposure to meat and risk of lymphoma: a multicenter case-control study from Europe
    Tina Moore
    Department of Lifestyle, Environment and Cancer, International Agency for Research on Cancer, Lyon, France
    Int J Cancer 121:2761-6. 2007
    ..Occupational exposure to meat does not appear to represent an important risk factor of lymphoma, although an increased risk of specific types of non-Hodgkin lymphoma cannot be excluded...
  14. ncbi request reprint Lung cancer and occupation in nonsmokers: a multicenter case-control study in Europe
    Ariana Zeka
    International Agency for Research on Cancer, Lyon, France
    Epidemiology 17:615-23. 2006
    ..Therefore, the present study aimed to investigate the association between lung cancer and occupation independent of smoking...
  15. pmc A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium
    James D McKay
    International Agency for Research on Cancer IARC, Lyon, France
    PLoS Genet 7:e1001333. 2011
    ..02). These results implicate two variants at 4q21 and 12q24 and further highlight three ADH variants in UADT cancer susceptibility...
  16. doi request reprint Exposure to ultraviolet radiation and risk of malignant lymphoma and multiple myeloma--a multicentre European case-control study
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 37:1080-94. 2008
    ..Three recent studies have reported a decreased risk of non-Hodgkin lymphoma (NHL) for high ultraviolet (UV) radiation exposure...
  17. ncbi request reprint Esophageal cancer in Central and Eastern Europe: tobacco and alcohol
    Mia Hashibe
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 120:1518-22. 2007
    ..A synergistic interaction between tobacco and alcohol was observed for the risk of esophageal SCC, highlighting the importance of both factors for esophageal cancers in Central and Eastern Europe...
  18. ncbi request reprint Contribution of tobacco and alcohol to the high rates of squamous cell carcinoma of the supraglottis and glottis in Central Europe
    Mia Hashibe
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 165:814-20. 2007
    ..Preventive efforts to encourage current smokers to quit are likely to be the most effective way to reduce the incidence of laryngeal cancer in this region...
  19. doi request reprint Indoor air pollution from solid fuels and risk of hypopharyngeal/laryngeal and lung cancers: a multicentric case-control study from India
    Amir Sapkota
    International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 37:321-8. 2008
    ..Although as much as 74% of the Indian population relies on solid fuels for cooking, very little information is available on cancer risk associated with these fuels in India...
  20. pmc Occupational exposure to asbestos and man-made vitreous fibres and risk of lung cancer: a multicentre case-control study in Europe
    Rafael Carel
    International Agency for Research on Cancer, Lyon, France
    Occup Environ Med 64:502-8. 2007
    ..To investigate the contribution of occupational exposure to asbestos and man-made vitreous fibres (MMVF) to lung cancer in high-risk populations in Europe...
  21. pmc Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals
    Esther H Lips
    International Agency for Research on Cancer IARC, Lyon, France
    Int J Epidemiol 39:563-77. 2010
    ....
  22. ncbi request reprint Sequence variants in cell cycle control pathway, X-ray exposure, and lung cancer risk: a multicenter case-control study in Central Europe
    Rayjean J Hung
    IARC, Lyon, France
    Cancer Res 66:8280-6. 2006
    ..However, a definite conclusion can only be drawn on replication by different studies among individuals who are highly exposed to IR...
  23. ncbi request reprint Exon 5 polymorphisms in the O6-alkylguanine DNA alkyltransferase gene and lung cancer risk in non-smokers exposed to second-hand smoke
    Catherine Cohet
    International Agency of Research on Cancer, Lyon, France
    Cancer Epidemiol Biomarkers Prev 13:320-3. 2004
    ....
  24. ncbi request reprint Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study
    Paul Brennan
    International Agency for Research on Cancer IARC, Lyon, France
    Hum Mol Genet 16:1794-801. 2007
    ..g. by forcing nearby stem cells to divide before they have repaired their own DNA damage from tobacco smoke). If so, reducing the rate of apoptosis by reducing CHEK2 activity could be protective-although not smoking would be far more so...
  25. ncbi request reprint Patterns of EGFR, HER2, TP53, and KRAS mutations of p14arf expression in non-small cell lung cancers in relation to smoking history
    Mounia Mounawar
    IARC, Lyon, France
    Cancer Res 67:5667-72. 2007
    ....
  26. ncbi request reprint Lung cancer risk and occupational exposure to meat and live animals
    Raika Durusoy
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 118:2543-7. 2006
    ..The authors identified a more consistent association with exposure to live animals...
  27. doi request reprint Lung cancer risk attributable to occupational exposures in a multicenter case-control study in Central and Eastern Europe
    Ann C Olsson
    International Agency for Research on Cancer, Lyon, France
    J Occup Environ Med 53:1262-7. 2011
    ..To estimate the lung cancer risk attributable to occupational lung carcinogens...
  28. doi request reprint Fruit and vegetable intake and overall cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Paolo Boffetta
    The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Natl Cancer Inst 102:529-37. 2010
    ..However, inconsistent results from many studies have not been able to conclusively establish an inverse association between fruit and vegetable intake and overall cancer risk...
  29. doi request reprint Multiple ADH genes are associated with upper aerodigestive cancers
    Mia Hashibe
    International Agency for Research on Cancer, Lyon, France
    Nat Genet 40:707-9. 2008
    ..0002 and 0.065, respectively). Both gene effects were independent of each other, implying that multiple ADH genes may be involved in upper aerodigestive cancer etiology...
  30. ncbi request reprint Lifestyle habits as prognostic factors in survival of laryngeal and hypopharyngeal cancer: a multicentric European study
    Rajesh P Dikshit
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 117:992-5. 2005
    ..Our results support the hypothesis that there is a role for dietary intervention to improve survival of laryngeal and hypopharyngeal cancer patients...
  31. pmc Lung cancer susceptibility locus at 5p15.33
    James D McKay
    International Agency for Research on Cancer IARC, Lyon, France
    Nat Genet 40:1404-6. 2008
    ..016). The susceptibility region contains two genes, TERT and CLPTM1L, suggesting that one or both may have a role in lung cancer etiology...
  32. ncbi request reprint Effect of cruciferous vegetables on lung cancer in patients stratified by genetic status: a mendelian randomisation approach
    Paul Brennan
    International Agency for Research on Cancer, Lyon, France
    Lancet 366:1558-60. 2005
    ..These data provide strong evidence for a substantial protective effect of cruciferous vegetable consumption on lung cancer...
  33. ncbi request reprint High cumulative risk of lung cancer death among smokers and nonsmokers in Central and Eastern Europe
    Paul Brennan
    Group of Genetic Epidemiology, International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 164:1233-41. 2006
    ..This substantial reduction in risk among former smokers confirms that lung cancer mortality in Central Europe over the next three decades will be determined by the extent to which current smokers can successfully quit smoking...
  34. ncbi request reprint Associations between ocular melanoma and other primary cancers: an international population-based study
    Ghislaine Scelo
    International Agency for Research on Cancer IARC, Lyon, France
    Int J Cancer 120:152-9. 2007
    ..The high SIR found for liver cancer may be explained by misclassification bias. Common etiological factors may be involved in ocular and prostate cancers...
  35. ncbi request reprint A pooled analysis of second primary pancreatic cancer
    Min Shen
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 163:502-11. 2006
    ..The elevated pancreatic cancer risk in young patients observed among several types of cancer implies a role of genetic factors. Radiotherapy is also suggested as a risk factor...
  36. pmc Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium
    Mia M Gaudet
    Department of Epidemiology and Population Health and of Obstetrics and Gynecology and Women s Health, Albert Einstein College of Medicine, Bronx, NY, USA
    Int J Epidemiol 39:1091-102. 2010
    ....
  37. doi request reprint Risk of second primary cancer among esophageal cancer patients: a pooled analysis of 13 cancer registries
    Shu Chun Chuang
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 17:1543-9. 2008
    ..The objective of this study is to assess the risk of second primary cancers following a first primary esophageal cancer as well as the risk of esophageal cancer as a second primary, following first primary cancers of other sites...
  38. ncbi request reprint Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review
    Rayjean J Hung
    Genetic Epidemiology Group, International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 162:925-42. 2005
    ..Recommendations for future studies include pooling of individual data to facilitate evaluation of multigenic effects and detailed analysis of effect modification by environmental exposure...
  39. ncbi request reprint Dietary risk factors for kidney cancer in Eastern and Central Europe
    Charles C Hsu
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 166:62-70. 2007
    ..The increased risk associated with dairy products, preserved vegetables, and red meat provides clues to the high rates of kidney cancer in this population...
  40. doi request reprint Risk of second primary cancer among patients with head and neck cancers: A pooled analysis of 13 cancer registries
    Shu Chun Chuang
    International Agency for Research on Cancer IARC, Lyon, France
    Int J Cancer 123:2390-6. 2008
    ..These patterns were consistent with the notion that the pattern of cancer in survivors of head and neck cancer is dominated by the effect of tobacco smoking and alcohol drinking...
  41. pmc Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls
    Darren R Brenner
    International Agency for Research on Cancer, Lyon, France
    Hum Genet 132:579-89. 2013
    ..HM allows for prior knowledge such as from bioinformatic sources to be incorporated into the analysis systematically, and it represents a complementary analytical approach to the conventional GWAS analysis...
  42. ncbi request reprint GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population
    Rayjean J Hung
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 110:598-604. 2004
    ..26 (95% CI = 1.06-9.95). SULT1A1 Arg213His polymorphism showed a marginal protective effect. These findings suggest that individual susceptibility to bladder cancer may be modulated by GSTM1, GSTT1 and NAT2 polymorphisms...
  43. doi request reprint Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions
    Karina Braga Ribeiro
    International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 40:489-502. 2011
    ..We have evaluated the HPV deoxyribonucleic acid (DNA) prevalence as well as the association between serological response to HPV infection and HNSCC in two distinct populations from Central Europe (CE) and Latin America (LA)...
  44. ncbi request reprint Occupational X-ray examinations and lung cancer risk
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 115:263-7. 2005
    ....
  45. pmc A U-shaped relationship between haematocrit and mortality in a large prospective cohort study
    Paolo Boffetta
    Institute for Transitional Epidemiology and the Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    Int J Epidemiol 42:601-15. 2013
    ..We investigated the association between baseline HCT and mortality in a prospective cohort study of 49,983 adult subjects in Iran with a broad spectrum of HCT values...
  46. ncbi request reprint Is the risk of lung cancer reduced among eczema patients?
    Marine Castaing
    Gene Environment Epidemiology Group, International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 162:542-7. 2005
    ..This study provides further evidence for an inverse association between history of eczema and lung cancer risk, which is unlikely to be due to chance, bias, or confounding...
  47. doi request reprint Exposure to diesel motor exhaust and lung cancer risk in a pooled analysis from case-control studies in Europe and Canada
    Ann C Olsson
    International Agency for Research on Cancer, Lyon, France
    Am J Respir Crit Care Med 183:941-8. 2011
    ..The epidemiologic evidence is evaluated as limited because most studies lack adequate control for potential confounders and only a few studies have reported on exposure-response relationships...
  48. pmc Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium
    Mia Hashibe
    IARC, Lifestyle, Environment and Cancer Group, Genetics and Epidemiology Cluster, Lyon, France
    Cancer Epidemiol Biomarkers Prev 18:541-50. 2009
    ..The magnitude of risk conferred by the interaction between tobacco and alcohol use on the risk of head and neck cancers is not clear because studies have used various methods to quantify the excess head and neck cancer burden...
  49. doi request reprint Sensitivity of the association between increased lung cancer risk and bitumen fume exposure to the assumptions in the assessment of exposure
    Frank de Vocht
    Gene Environment Epidemiology Group, International Agency for Research on Cancer IARC, Lyon, France
    Int Arch Occup Environ Health 82:723-33. 2009
    ..Sensitivity analyses were conducted to assess whether these associations were robust to assumptions in the exposure assessment for which support could not be obtained due to lack of either measurements or direct observations...
  50. doi request reprint Alcohol drinking and esophageal squamous cell carcinoma with focus on light-drinkers and never-smokers: a systematic review and meta-analysis
    Farhad Islami
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 129:2473-84. 2011
    ..Light alcohol intake appears to be associated to ESCC mainly in studies in Asia, which suggests a possible role of genetic susceptibility factors...
  51. pmc Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk
    Manuela Marron
    International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 39:182-96. 2010
    ..However, it is unclear how many years must pass following cessation of these habits before the risk is reduced, and whether the risk ultimately declines to the level of never smokers or never drinkers...
  52. ncbi request reprint Second primary cancers in patients with nasopharyngeal carcinoma: a pooled analysis of 13 cancer registries
    Ghislaine Scelo
    International Agency for Research on Cancer, 150 cours Albert Thomas, Lyon, 69008, France
    Cancer Causes Control 18:269-78. 2007
    ..To study the risk of second primary cancers in nasopharyngeal carcinoma (NPC) patients and the risk of NPC as second primary cancer...
  53. ncbi request reprint Lack of association between -251 T>A polymorphism of IL8 and lung cancer risk
    Daniele Campa
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 14:2457-8. 2005
  54. ncbi request reprint Cancer mortality among European asphalt workers: an international epidemiological study. I. Results of the analysis based on job titles
    Paolo Boffetta
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Am J Ind Med 43:18-27. 2003
    ..Inhalation of bitumen fumes is potentially carcinogenic to humans...
  55. ncbi request reprint A cross-sectional study of cardiovascular disease and associated factors
    Farhad Islami
    Tisch Cancer Institute and Institute for Transitional Epidemiology, Mount Sinai School of Medicine, New York, United States
    Ann Agric Environ Med 18:255-9. 2011
    ..Data on risk factors of CVD in this country are limited. The presented study investigated risk factors of self-reported CVD within the Polish- Norwegian Study (PONS)...
  56. doi request reprint Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations
    Mazda Jenab
    Lifestyle and Cancer Group, IARC, 150 cours Albert Thomas, 69008, Lyon, France
    Cancer Epidemiol Biomarkers Prev 18:2485-91. 2009
    ..These results confirm a role for the BsmI polymorphism of the VDR gene in CRC risk, independent of serum 25OHD concentration and dietary calcium intake...
  57. ncbi request reprint Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer
    Mia Hashibe
    International Agency for Research on Cancer, Lyon, France
    Cancer Epidemiol Biomarkers Prev 12:1509-17. 2003
    ....
  58. doi request reprint An estimate of cancers attributable to occupational exposures in France
    Paolo Boffetta
    International Prevention Research Institute, Lyon, France
    J Occup Environ Med 52:399-406. 2010
    ..To perform a quantitative estimate of the proportion of cancers attributable to occupational exposures in France in 2000...
  59. ncbi request reprint Oral health and risk of squamous cell carcinoma of the head and neck and esophagus: results of two multicentric case-control studies
    Neela Guha
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 166:1159-73. 2007
    ..18, 95% CI: 1.04, 4.59). These results indicate that periodontal disease (as indicated by poor condition of the mouth and missing teeth) and daily mouthwash use may be independent causes of cancers of the head, neck, and esophagus...
  60. doi request reprint N2-ethyldeoxyguanosine as a potential biomarker for assessing effects of alcohol consumption on DNA
    Silvia Balbo
    IARC, Cours Albert Thomas 150, 69008, Lyon, France
    Cancer Epidemiol Biomarkers Prev 17:3026-32. 2008
    ..These results show the feasibility of quantifying N2-ethyl-dGuo in small-volume blood samples and are consistent with the hypothesis that ethanol contributes to carcinogenesis through DNA adducts formation...
  61. pmc Vitamin or mineral supplement intake and the risk of head and neck cancer: pooled analysis in the INHANCE consortium
    Qian Li
    National Office of Cancer Prevention and Control, Cancer Hospital Institute, Chinese Academy of Medical Sciences, Beijing, China International Agency for Research on Cancer, Lyon, France
    Int J Cancer 131:1686-99. 2012
    ..36, 95% CI = 0.16-0.83), but linear trends were not observed for the frequency or duration of any supplement intake. We did not observe any strong associations between vitamin or mineral supplement intake and the risk of HNC...
  62. doi request reprint Serum levels of IGF-I, IGFBP-3 and colorectal cancer risk: results from the EPIC cohort, plus a meta-analysis of prospective studies
    Sabina Rinaldi
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 126:1702-15. 2010
    ..07 [1.01-1.14] for 1 standard deviation increase in IGF-I). Overall, data from our present study and previous prospective studies combined indicate a relatively modest association of colorectal cancer risk with serum IGF-I...
  63. pmc Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer
    Anupam Paliwal
    International Agency for Research on Cancer, Lyon, France
    Cancer Res 70:2779-88. 2010
    ..1 and lung cancer, and suggest nAChRs to be theranostic targets for cancer detection and chemoprevention...
  64. doi request reprint Cigar and pipe smoking and cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
    Valerie A McCormack
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 127:2402-11. 2010
    ..Cigar and pipe smoking is not a safe alternative to cigarette smoking. The lower cancer risk of cigar and pipe smokers as compared to cigarette smokers is explained by lesser degree of inhalation and lower smoking intensity...
  65. ncbi request reprint Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma
    Rajesh P Dikshit
    Gene Environment Epidemiology Group, International Agency for Research on Cancer, Lyon, France
    Cancer 103:2326-33. 2005
    ..However, to the authors' knowledge little is known regarding the risk factors for developing SPTs or about the strategy to be followed to avoid them...
  66. ncbi request reprint Glutathione S-transferases M1, T1, and P1 and breast cancer: a pooled analysis
    Florian D Vogl
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 13:1473-9. 2004
    ..The results conclusively show that single gene GST polymorphisms do not confer a substantial risk of breast cancer to its carriers. Furthermore, GSTs did not interact with smoking or reproductive history to modify cancer risk...
  67. pmc Bladder cancer incidence and exposure to polycyclic aromatic hydrocarbons among asphalt pavers
    Igor Burstyn
    International Agency for Research on Cancer, Lyon, France
    Occup Environ Med 64:520-6. 2007
    ..To investigate the association between exposures to polycyclic aromatic hydrocarbons (PAH) that arises during asphalt paving, and risk of bladder cancer...
  68. doi request reprint CDH1 gene polymorphisms, smoking, Helicobacter pylori infection and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    Mazda Jenab
    International Agency for Research on Cancer IARC WHO, Lyon, France
    Eur J Cancer 44:774-80. 2008
    ..However, three CDH1 polymorphisms in the same haplotype block, including the CDH1-160C/A, interacted with smoking to increase GC risk in smokers but not in never smokers. These findings should be confirmed in larger independent studies...
  69. ncbi request reprint Chromosomal aberrations and cancer risk: results of a cohort study from Central Europe
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Am J Epidemiol 165:36-43. 2007
    ....
  70. ncbi request reprint Smokeless tobacco and increased risk of hypopharyngeal and laryngeal cancers: a multicentric case-control study from India
    Amir Sapkota
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 121:1793-8. 2007
    ....
  71. ncbi request reprint Hypermethylation, risk factors, clinical characteristics, and survival in 235 patients with laryngeal and hypopharyngeal cancers
    Rajesh P Dikshit
    Department of Lifestyle, Environment, and Cancer, International Agency for Research on Cancer, Lyon, France
    Cancer 110:1745-51. 2007
    ..The authors investigated the role played by the hypermethylation of 4 cancer-related genes in the survival of patients who had laryngeal and hypopharyngeal cancer and in the occurrence of second primary tumors...
  72. doi request reprint Serum B vitamin levels and risk of lung cancer
    Mattias Johansson
    International Agency for Research on Cancer, Lyon, France
    JAMA 303:2377-85. 2010
    ..B vitamins and factors related to 1-carbon metabolism help to maintain DNA integrity and regulate gene expression and may affect cancer risk...
  73. doi request reprint A cohort study of cancer among sarcoidosis patients
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 124:2697-700. 2009
    ..These results provide further evidence for an increased risk of specific cancers in patients with sarcoidosis, but do not support any additional increase in overall cancer risk...
  74. ncbi request reprint Tobacco smoking, alcohol drinking and non-Hodgkin's lymphoma: A European multicenter case-control study (Epilymph)
    Herve Besson
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 119:901-8. 2006
    ..The results of this large-scale European study did not support an association between tobacco and NHL and suggested a protective effect of alcohol on development of NHL for men and in non-Mediterranean countries...
  75. doi request reprint Interaction between cigarette smoking and hepatitis B and C virus infection on the risk of liver cancer: a meta-analysis
    Shu Chun Chuang
    IARC, International Prevention Research Institute, 95 cours Lafayette, 69006 Lyon, France
    Cancer Epidemiol Biomarkers Prev 19:1261-8. 2010
    ..We conducted a meta-analysis to evaluate the interaction of HBV and HCV infection and cigarette smoking on the risk of HCC...
  76. pmc Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium
    Julia E Heck
    Lifestyle, Environment, and Cancer Group, International Agency for Research on Cancer, Lyon, France
    Int J Epidemiol 39:166-81. 2010
    ..Sexual contact may be the means by which head and neck cancer patients are exposed to human papillomavirus (HPV)...
  77. doi request reprint Genome-wide association study of HPV seropositivity
    Dan Chen
    International Agency for Research on Cancer, Lyon, France
    Hum Mol Genet 20:4714-23. 2011
    ..This study provides a proof of principle that genetic variation plays a role in antibody reactivity to HPV infection...
  78. doi request reprint Smokeless tobacco and cancer
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Lancet Oncol 9:667-75. 2008
    ..Animal carcinogenicity studies strongly support clinical results. Cancer risk of smokeless tobacco users is probably lower than that of smokers, but higher than that of non-tobacco users...
  79. ncbi request reprint A geographic correlation study of the incidence of pancreatic and other cancers in Whites
    Paolo Boffetta
    Gene Environment Epidemiology Group, International Agency for Research on Cancer, Lyon, France
    Eur J Epidemiol 21:39-46. 2006
    ..Tobacco smoking is a plausible explanation of the association between pancreatic and lung cancer; the association with kidney cancer likely reflects additional common etiologic and pathogenetic factors of the two neoplasms...
  80. ncbi request reprint Contribution of environmental factors to cancer risk
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Br Med Bull 68:71-94. 2003
    ....
  81. ncbi request reprint Amount of DNA in plasma and cancer risk: a prospective study
    Emmanuelle Gormally
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 111:746-9. 2004
    ..e., a time elapsed between blood drawing and disease onset lower than 36 months. This was particularly true for COPD deaths (OR = 12.7; 95% CI = 1.57-103) and leukemia (OR = 2.37; 95% CI = 1.20-4.67)...
  82. ncbi request reprint Cancer incidence among male Swedish veterinarians and other workers of the veterinary industry: a record-linkage study
    Noemie Travier
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Cancer Causes Control 14:587-93. 2003
    ..To investigate the risk of cancer among veterinarians in a large record-linkage study from Sweden...
  83. ncbi request reprint Alcohol and cancer: benefits in addition to risks?
    Paolo Boffetta
    Gene Environment Epidemiology Group, International Agency for Research on Cancer, Lyon, France
    Lancet Oncol 6:443-4. 2005
  84. ncbi request reprint Cancer incidence of dry cleaning, laundry and ironing workers in Sweden
    Noomie Travier
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Scand J Work Environ Health 28:341-8. 2002
    ..This study investigated the risk of cancer among dry cleaners, launderers, and pressers in a large record-linkage study in Sweden...
  85. ncbi request reprint Alcohol and cancer
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Lancet Oncol 7:149-56. 2006
    ..Alcohol consumption is increasing in many countries and is an important cause of cancer worldwide...
  86. ncbi request reprint Cancer mortality among butchers: a 24-state death certificate study
    Herve Besson
    International Agency for Research on Cancer, Lyon, France
    J Occup Environ Med 48:289-93. 2006
    ..The objective of this study was to document cancer mortality among American butchers...
  87. ncbi request reprint The burden of cancer attributable to alcohol drinking
    Paolo Boffetta
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 119:884-7. 2006
    ..Although our estimates are based on simplified assumptions, the burden of alcohol-associated cancer appears to be substantial and needs to be considered when making public health recommendations on alcohol drinking...
  88. doi request reprint A prospective study of gout and cancer
    Paolo Boffetta
    International Agency for Research on Cancer, 150 cours Albert Thomas, Lyon, France
    Eur J Cancer Prev 18:127-32. 2009
    ..With the exception of lung cancer, the risk remained elevated during the entire follow-up. This study provides no evidence of a protective effect of uric acid. Hyperuricemia may be an early manifestation of the carcinogenic process...
  89. ncbi request reprint Meta-analysis of studies of occupational exposure to vinyl chloride in relation to cancer mortality
    Paolo Boffetta
    Unit of Environmental Cancer Epidemiology, International Agency for Research on Cancer, Lyon, France
    Scand J Work Environ Health 29:220-9. 2003
    ..A meta-analysis was made of studies addressing occupational exposure to vinyl chloride in relation to cancer mortality...