A Pautsch

Summary

Affiliation: Boehringer Ingelheim

Publications

  1. ncbi Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation
    A Pautsch
    Boehringer Ingelheim Pharma KG Deutschland, Birkendorferstrasse 65, D 88400 Biberach, Germany
    Structure 9:955-65. 2001
  2. ncbi High-resolution structure of the OmpA membrane domain
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Albertstrasse 21, Freiburg im Breisgau, D 79104, Germany
    J Mol Biol 298:273-82. 2000
  3. ncbi Structure of the outer membrane protein A transmembrane domain
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Freiburg im Breisgau, Germany
    Nat Struct Biol 5:1013-7. 1998
  4. ncbi Strategy for membrane protein crystallization exemplified with OmpA and OmpX
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Freiburg im Breisgau, Germany
    Proteins 34:167-72. 1999

Collaborators

Detail Information

Publications4

  1. ncbi Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation
    A Pautsch
    Boehringer Ingelheim Pharma KG Deutschland, Birkendorferstrasse 65, D 88400 Biberach, Germany
    Structure 9:955-65. 2001
    ..Structures of the homologous insulin receptor kinase (IRK) exist in an open, unphosphorylated form and a closed, trisphosphorylated form...
  2. ncbi High-resolution structure of the OmpA membrane domain
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Albertstrasse 21, Freiburg im Breisgau, D 79104, Germany
    J Mol Biol 298:273-82. 2000
    ..The beta-barrel was related to those of lipocalins. Two further crystal forms with exceptionally dense packing arrangements were established at medium resolution...
  3. ncbi Structure of the outer membrane protein A transmembrane domain
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Freiburg im Breisgau, Germany
    Nat Struct Biol 5:1013-7. 1998
    ..The structure constitutes a beta-barrel membrane anchor that appears to be the outer membrane equivalent of the single-chain alpha-helix anchor of the inner membrane...
  4. ncbi Strategy for membrane protein crystallization exemplified with OmpA and OmpX
    A Pautsch
    Institut fur Organische Chemie und Biochemie, Albert Ludwigs Universitat, Freiburg im Breisgau, Germany
    Proteins 34:167-72. 1999
    ..The procedure involved semi-directed mutagenesis, mass production into inclusion bodies, and (re)naturation therefrom; it should be applicable for a broader range of membrane proteins...