Karin M Danzer

Summary

Affiliation: Boehringer Ingelheim

Publications

  1. ncbi Different species of alpha-synuclein oligomers induce calcium influx and seeding
    Karin M Danzer
    Central Nervous System Research, Boehringer Ingelheim Pharma, 88397 Biberach, Germany
    J Neurosci 27:9220-32. 2007
  2. ncbi Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers
    Karin M Danzer
    Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 103:2401-7. 2007
  3. doi Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers
    Marcus Kostka
    CNS Research, Boehringer Ingelheim Pharma GmbH and Co KG, CNS Research, Birkendorferstrasse 65, 88397 Biberach, Germany
    J Biol Chem 283:10992-1003. 2008

Detail Information

Publications3

  1. ncbi Different species of alpha-synuclein oligomers induce calcium influx and seeding
    Karin M Danzer
    Central Nervous System Research, Boehringer Ingelheim Pharma, 88397 Biberach, Germany
    J Neurosci 27:9220-32. 2007
    ..This has important implications for the development of disease-modifying drugs for the treatment of PD and other synucleinopathies...
  2. ncbi Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers
    Karin M Danzer
    Boehringer Ingelheim Pharma GmbH and Co KG, Biberach, Germany
    J Neurochem 103:2401-7. 2007
    ..Thus, PAKs may represent a target for various neurotoxic protein oligomers, and signaling deficits may contribute to the behavioral defects in chronic neurodegenerative diseases...
  3. doi Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers
    Marcus Kostka
    CNS Research, Boehringer Ingelheim Pharma GmbH and Co KG, CNS Research, Birkendorferstrasse 65, 88397 Biberach, Germany
    J Biol Chem 283:10992-1003. 2008
    ..Moreover, scanning for intensely fluorescent targets allows high throughput screening for aggregation inhibitors and may provide new approaches for drug development and therapy...