- Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug designBrian N Cook
Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, Inc, 900 Ridgebury Road, PO Box 368, Ridgefield, CT 06877, USA
Bioorg Med Chem Lett 19:773-7. 2009....
- 5-Aminomethylbenzimidazoles as potent ITK antagonistsDoris Riether
Medicinal Chemistry Department, Boehringer Ingelheim Pharmaceuticals Inc, 900 Ridgebury Rd PO Box 368, Ridgefield, CT 06877, USA
Bioorg Med Chem Lett 19:1588-91. 2009..SAR studies around the benzylamines and the identification of 10n and 10o as excellent tools for proof-of-concept studies are described...