Brian N Cook

Summary

Affiliation: Boehringer Ingelheim

Publications

  1. ncbi Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design
    Brian N Cook
    Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, Inc, 900 Ridgebury Road, PO Box 368, Ridgefield, CT 06877, USA
    Bioorg Med Chem Lett 19:773-7. 2009
  2. ncbi 5-Aminomethylbenzimidazoles as potent ITK antagonists
    Doris Riether
    Medicinal Chemistry Department, Boehringer Ingelheim Pharmaceuticals Inc, 900 Ridgebury Rd PO Box 368, Ridgefield, CT 06877, USA
    Bioorg Med Chem Lett 19:1588-91. 2009

Detail Information

Publications2

  1. ncbi Discovery of potent inhibitors of interleukin-2 inducible T-cell kinase (ITK) through structure-based drug design
    Brian N Cook
    Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, Inc, 900 Ridgebury Road, PO Box 368, Ridgefield, CT 06877, USA
    Bioorg Med Chem Lett 19:773-7. 2009
    ....
  2. ncbi 5-Aminomethylbenzimidazoles as potent ITK antagonists
    Doris Riether
    Medicinal Chemistry Department, Boehringer Ingelheim Pharmaceuticals Inc, 900 Ridgebury Rd PO Box 368, Ridgefield, CT 06877, USA
    Bioorg Med Chem Lett 19:1588-91. 2009
    ..SAR studies around the benzylamines and the identification of 10n and 10o as excellent tools for proof-of-concept studies are described...