Bela Bodey

Summary

Publications

  1. ncbi request reprint The significance of immunohistochemistry in the diagnosis and therapy of neoplasms
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Expert Opin Biol Ther 2:371-93. 2002
  2. ncbi request reprint Restoration of the thymic cellular microenvironment following autologous bone marrow transplantation
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    In Vivo 16:127-40. 2002
  3. ncbi request reprint Expression in childhood primary brain tumors of NY-ESO-1, a cancer/testis antigen: an immunohistochemical study
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    In Vivo 22:83-7. 2008
  4. ncbi request reprint Spontaneous regression of neoplasms: new possibilities for immunotherapy
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Expert Opin Biol Ther 2:459-76. 2002
  5. ncbi request reprint Neuroendocrine influence on thymic haematopoiesis via the reticulo-epithelial cellular network
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Expert Opin Ther Targets 6:57-72. 2002
  6. ncbi request reprint Thymic hormones in cancer diagnostics and treatment
    B Bodey
    Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Expert Opin Biol Ther 1:93-107. 2001
  7. ncbi request reprint Genetically engineered antibodies for direct antineoplastic treatment and systematic delivery of various therapeutic agents to cancer cells
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California and Department of Pediatrics, Division of Hematology and Oncology, Childrens Hospital, Los Angeles, Los Angeles, CA, USA
    Expert Opin Biol Ther 1:603-17. 2001
  8. ncbi request reprint Matrix metalloproteinases in neoplasm-induced extracellular matrix remodeling in breast carcinomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 21:2021-8. 2001
  9. ncbi request reprint Immunocytochemical detection of leukocyte-associated and apoptosis-related antigen expression in childhood brain tumors
    B Bodey
    Department of Pathology, University of Southern California, 8000 1 Canby Avenue, Reseda, Los Angeles, CA, USA
    Crit Rev Oncol Hematol 39:3-16. 2001
  10. ncbi request reprint Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung
    B Bodey
    Department of Pathology, University of Southern California, 8000 1 Canby Avenue, Reseda, CA 91335, USA
    In Vivo 15:175-80. 2001

Collaborators

Detail Information

Publications51

  1. ncbi request reprint The significance of immunohistochemistry in the diagnosis and therapy of neoplasms
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Expert Opin Biol Ther 2:371-93. 2002
    ....
  2. ncbi request reprint Restoration of the thymic cellular microenvironment following autologous bone marrow transplantation
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    In Vivo 16:127-40. 2002
    ..Our radiation, stem cell transplantation, and hormone treatment experiments in animals resulted in age- and time-dependent regeneration of the cytoarchitecture of the TCM, as well as intrathymic lymphopoiesis...
  3. ncbi request reprint Expression in childhood primary brain tumors of NY-ESO-1, a cancer/testis antigen: an immunohistochemical study
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    In Vivo 22:83-7. 2008
    ....
  4. ncbi request reprint Spontaneous regression of neoplasms: new possibilities for immunotherapy
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Expert Opin Biol Ther 2:459-76. 2002
    ..The application of the newest immunological, molecular biological and genetic insights for more individualised and adequate antineoplastic immunotherapy (alternative biotherapy) is also discussed...
  5. ncbi request reprint Neuroendocrine influence on thymic haematopoiesis via the reticulo-epithelial cellular network
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Expert Opin Ther Targets 6:57-72. 2002
    ..The intrathymic T-lymphocyte selection is a complex, multistep process, influenced by several functionally specialised RE cells and under immuno-neuroendocrine regulation control reflecting the dynamic changes of the mammalian organism...
  6. ncbi request reprint Thymic hormones in cancer diagnostics and treatment
    B Bodey
    Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    Expert Opin Biol Ther 1:93-107. 2001
    ..Generally, haematopoietic toxicity of every chemotherapeutical clinical trial can be reduced significantly by the immunotherapy, compared to 50% in patients treated with chemotherapy alone...
  7. ncbi request reprint Genetically engineered antibodies for direct antineoplastic treatment and systematic delivery of various therapeutic agents to cancer cells
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California and Department of Pediatrics, Division of Hematology and Oncology, Childrens Hospital, Los Angeles, Los Angeles, CA, USA
    Expert Opin Biol Ther 1:603-17. 2001
    ..In addition, a variety of agents (e.g. toxins, radionuclides, chemotherapeutic drugs) have been conjugated to mouse and human mAbs for selective delivery to neoplastic cells...
  8. ncbi request reprint Matrix metalloproteinases in neoplasm-induced extracellular matrix remodeling in breast carcinomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 21:2021-8. 2001
    ....
  9. ncbi request reprint Immunocytochemical detection of leukocyte-associated and apoptosis-related antigen expression in childhood brain tumors
    B Bodey
    Department of Pathology, University of Southern California, 8000 1 Canby Avenue, Reseda, Los Angeles, CA, USA
    Crit Rev Oncol Hematol 39:3-16. 2001
    ....
  10. ncbi request reprint Invasion and metastasis: the expression and significance of matrix metalloproteinases in carcinomas of the lung
    B Bodey
    Department of Pathology, University of Southern California, 8000 1 Canby Avenue, Reseda, CA 91335, USA
    In Vivo 15:175-80. 2001
    ....
  11. ncbi request reprint Immunocytochemical detection of the expression of members of the matrix metalloproteinase family in adenocarcinomas of the pancreas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 15:71-6. 2001
    ....
  12. ncbi request reprint Cancer-testis antigens: promising targets for antigen directed antineoplastic immunotherapy
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, 8000 1 Canby Avenue, Reseda, CA 91335, USA
    Expert Opin Biol Ther 2:577-84. 2002
    ..Immunotherapeutic protocols directed against the CTAs have already been initiated to analyse the induction of antigen-specific cellular and humoral immune responses in vivo...
  13. ncbi request reprint MAGE-1, a cancer/testis-antigen, expression in childhood astrocytomas as an indicator of tumor progression
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, and Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    In Vivo 16:583-8. 2002
    ....
  14. ncbi request reprint Thymic reticulo-epithelial cells: key cells of neuroendocrine regulation
    Bela Bodey
    University of Southern California, Department of Pathology, Keck School of Medicine, Los Angeles, CA, USA
    Expert Opin Biol Ther 7:939-49. 2007
    ..The thymic RE cell network represents an important cellular and humoral microenvironment in the neuroendocrine homeopathic regulatory mechanisms of the multicellular organism...
  15. ncbi request reprint Cyclooxygenase-2 (COX-2) overexpression in childhood brain tumors
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, USA
    In Vivo 20:519-25. 2006
    ..In view of these findings, it would appear likely that COX-2 inhibitors may represent a chemo-preventive tool in treating childhood brain tumors, which are the leading cause of solid tumor cancer death in children under the age of 20...
  16. ncbi request reprint Up-regulation of VEGF expression and related neo-angiogenesis in childhood high-grade gliomas: implications for anti-angiogenic anti-neoplastic therapy
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, USA
    In Vivo 20:511-8. 2006
    ....
  17. ncbi request reprint Mechanisms and markers of carcinogenesis and neoplastic progression
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Reseda, Los Angeles, CA 91335, USA
    Expert Opin Biol Ther 5:1317-32. 2005
    ..This paper reviews carcinogenesis from nutritional, genetic and molecular, and humoral aspects, and discusses the importance of tumour markers in the diagnosis and therapeutic management of human cancer...
  18. ncbi request reprint Epidermal growth factor receptor (EGFR) expression in childhood brain tumors
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    In Vivo 19:931-41. 2005
    ..Moreover, c-erbB-2 (HER-2) expression may also be of use in better classifying brain tumors...
  19. ncbi request reprint Immunocytochemical detection of members of the caspase cascade of apoptosis in childhood medulloblastomas
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    In Vivo 19:749-60. 2005
    ....
  20. ncbi request reprint Survivin expression in childhood medulloblastomas: a possible diagnostic and prognostic marker
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, USA
    In Vivo 18:713-8. 2004
    ..Furthermore, the almost exclusive neoplastic expression of survivin will allow development of new antineoplastic, immunotherapeutic strategies...
  21. ncbi request reprint Immunocytochemical detection of members of the caspase cascade of apoptosis in high-grade astrocytomas
    Bela Bodey
    Department of Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    In Vivo 18:593-602. 2004
    ..We suggest that caspase-3, -6, -8 and -9 immunocytochemistry could have prognostic and immunotherapeutic significance in the treatment of these highly malignant glial tumors...
  22. ncbi request reprint Antigen presentation by dendritic cells and their significance in antineoplastic immunotherapy
    Bela Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    In Vivo 18:81-100. 2004
    ....
  23. ncbi request reprint Expression of proline-directed protein kinase, (p34cdc2/p58cyclin A), a novel cell proliferation marker in childhood brain tumors
    B Bodey
    Department of Pathology, Keck School of Medicine, University of Southern California, Childrens Center for Cancer and Blood Diseases, Childrens Hospital Los Angeles, Los Angeles, CA, USA
    In Vivo 16:589-94. 2002
    ..Further systematic neoplasm studies and regular employment of these two polyclonal antibodies for immunocytochemical screening experiments are necessary to determine their true diagnostic and prognostic significance...
  24. ncbi request reprint Immunocytochemical detection of matrix metalloproteinase expression in prostate cancer
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 15:65-70. 2001
    ....
  25. ncbi request reprint Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 15:57-64. 2001
    ....
  26. ncbi request reprint Significant differences in the matrix metalloproteinase expression profiles of spontaneous medulloblastomas/primitive neuroectodermal tumors as compared with their xenografted, established tumor cell line derived counterparts
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 14:675-82. 2000
    ....
  27. ncbi request reprint Novel insights into the function of the thymic Hassall's bodies
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    In Vivo 14:407-18. 2000
    ....
  28. ncbi request reprint Review of thymic hormones in cancer diagnosis and treatment
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    Int J Immunopharmacol 22:261-73. 2000
    ....
  29. ncbi request reprint Fas (APO-1, CD95) receptor expression and new options for immunotherapy in childhood medulloblastomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    Anticancer Res 19:3293-314. 1999
    ..It seems that the therapeutical use of FasR-FasL (main apoptotic pathway) represents a new and exciting immunotherapeutical possibility in the treatment of primary childhood neuroectodermal tumors...
  30. ncbi request reprint Immunophenotypical analysis and immunobiology of childhood brain tumors
    B Bodey
    University of Southern California, Los Angeles, USA
    Anticancer Res 19:2973-92. 1999
    ..An indirect, four-step, enzyme linked [alkaline phosphatase (AP) and peroxidase (PO)], biotin-streptavidin based, antigen detection technique was employed. (ABSTRACT TRUNCATED)..
  31. ncbi request reprint Genetically engineered monoclonal antibodies for direct anti-neoplastic treatment and cancer cell specific delivery of chemotherapeutic agents
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California, Los Angeles, CA, USA
    Curr Pharm Des 6:261-76. 2000
    ..Finally, we propose that MoAB-based immunotherapy be accepted as a conventional form of therapy and employed not only in terminal cancer patients but also, for instance, during and following surgical resection...
  32. ncbi request reprint Fas (Apo-1, CD95) receptor expression in childhood astrocytomas. Is it a marker of the major apoptotic pathway or a signaling receptor for immune escape of neoplastic cells?
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    In Vivo 13:357-73. 1999
    ..It seems that the therapeutical use of FasR-FasL (main apoptotic pathway) may represent a new and exciting type of immunotherapy in the treatment of primary childhood glial tumors...
  33. ncbi request reprint Molecular biological ontogenesis of the thymic reticulo-epithelial cell network during the organization of the cellular microenvironment
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    In Vivo 13:267-94. 1999
    ..Intrathymic T lymphocyte selection is a complex, multistep process, influenced by several functionally specialized RE cell subtypes and under constant immuno-neuroendocrine regulation, reflecting the dynamic changes of the organism...
  34. ncbi request reprint The role of zinc in pre- and postnatal mammalian thymic immunohistogenesis
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California, Los Angeles, USA
    In Vivo 12:695-722. 1998
    ..In PBMCs, zinc induces several cytokines, predominantly IL-1, IL-6 and TNF-alpha, and therefore, has an immense immunoregulative capacity. (ABSTRACT TRUNCATED)..
  35. ncbi request reprint Intrathymic non-lymphatic hematopoiesis during mammalian ontogenesis
    B Bodey
    University of Southern California, Los Angeles, USA
    In Vivo 12:599-618. 1998
    ....
  36. ncbi request reprint Over-expression of endoglin (CD105): a marker of breast carcinoma-induced neo-vascularization
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California, Los Angeles, USA
    Anticancer Res 18:3621-8. 1998
    ..Further studies should substantiate the importance of EDG expression in the earliest possible detection, diagnosis and NRA inhibition-based treatment of solid tumors, including BCs...
  37. ncbi request reprint Immunocytochemical detection of the homeobox B3, B4, and C6 gene products within the human thymic cellular microenvironment
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    In Vivo 14:419-24. 2000
    ..The precise role of these and other HOX gene products in the various steps of intrathymic T lymphopoieis should be elucidated through further basic molecular biological research...
  38. ncbi request reprint Controversies on the prognostic significance of tumor infiltrating leukocytes in solid human tumors
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    Anticancer Res 20:1759-68. 2000
    ....
  39. ncbi request reprint Matrix metalloproteinase expression in childhood medulloblastomas/primitive neuroectodermal tumors
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 14:667-73. 2000
    ..Further characterization of the expression and utilization of MMPs and their inhibitors in the progression of solid human malignancies should lead to the development of novel anti-cancer therapies...
  40. ncbi request reprint Prognostic significance of matrix metalloproteinase expression in colorectal carcinomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    In Vivo 14:659-66. 2000
    ..Further characterization of the expression and utilization of MMPs and their inhibitors in the progression of solid human neoplasms should lead to the development of novel anti-cancer therapies...
  41. ncbi request reprint Immunocytochemical detection of MMP-3 and -10 expression in hepatocellular carcinomas
    B Bodey
    Department of Pathology, University of Southern California, 8000 1 Canby Avenue, Reseda, CA 91335, USA
    Anticancer Res 20:4585-90. 2000
    ..No immunoreactivity was detected using antibodies directed against MMP-2, -9, and -13...
  42. ncbi request reprint Matrix metalloproteinase expression in childhood astrocytomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:3287-92. 2000
    ....
  43. ncbi request reprint Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in breast carcinomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:3281-6. 2000
    ..Therefore, we are always seeking novel tumor associated antigens (TAAs), including oncofetal antigens, to use as molecular targets in cancer cell directed fourth modality immunotherapy...
  44. ncbi request reprint Homeobox B3, B4, and C6 gene product expression in osteosarcomas as detected by immunocytochemistry
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:2717-21. 2000
    ..The significance of the expression of class I HOX proteins in the pathobiology, diagnosis and prognostication of human OS should be established by further investigations...
  45. ncbi request reprint Immunocytochemical detection of homeobox B3, B4, and C6 gene product expression in lung carcinomas
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:2711-6. 2000
    ..The significance of these novel oncofetal antigens in tumor cell biology and as target molecules in the immunotherapy of lung carcinomas should be established by future studies...
  46. ncbi request reprint Failure of cancer vaccines: the significant limitations of this approach to immunotherapy
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:2665-76. 2000
    ....
  47. ncbi request reprint The role of the reticulo-epithelial (RE) cell network in the immuno-neuroendocrine regulation of intrathymic lymphopoiesis
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles, USA
    Anticancer Res 20:1871-88. 2000
    ..abstract trunca..
  48. ncbi request reprint Immunocytochemical detection of the homeobox B3, B4, and C6 gene products in childhood medulloblastomas/primitive neuroectodermal tumors
    B Bodey
    Department of Pathology, University of Southern California, Los Angeles 91335, USA
    Anticancer Res 20:1769-80. 2000
    ..The value of these genes and proteins in the early diagnosis and possible treatment of various human neoplasms, including childhood brain tumors, should be assessed in further immunocytochemical and molecular biological experiments...
  49. ncbi request reprint MTH-68/H oncolytic viral treatment in human high-grade gliomas
    L K Csatary
    United Cancer Research Institute, Alexandria, VA 22307, USA
    J Neurooncol 67:83-93. 2004
    ....
  50. ncbi request reprint Immunocytochemical detection of endoglin is indicative of angiogenesis in malignant melanoma
    B Bodey
    Department of Pathology, School of Medicine, University of Southern California, Los Angeles, USA Bodey
    Anticancer Res 18:2701-10. 1998
    ..The importance of TGF-beta in all of the various aspects of neoplastic transformation, as well as malignant disease progression should also be studied more extensively in the future...
  51. ncbi request reprint Racial differences in childhood tumors
    Hans E Kaiser
    International Society for the Study of Comparative Oncology, Inc, Silver Spring, MD 20901, USA
    In Vivo 16:417-22. 2002
    ..Special emphasis was put on the racial and other variabilities producing various combinations and specific responses to treatment...