Christopher C Blyth

Summary

Publications

  1. pmc Detection of occult Scedosporium species in respiratory tract specimens from patients with cystic fibrosis by use of selective media
    C C Blyth
    Centre of Infectious Diseases and Microbiology Laboratory Services, ICPMR, Westmead Hospital, Darcy Rd, Westmead, NSW 2145, Australia
    J Clin Microbiol 48:314-6. 2010
  2. pmc Influenza outbreaks during World Youth Day 2008 mass gathering
    Christopher C Blyth
    Westmead Hospital, Sydney, New South Wales, Australia
    Emerg Infect Dis 16:809-15. 2010
  3. doi request reprint The impact of bacterial and viral co-infection in severe influenza
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research ICPMR, Westmead Hospital, Sydney, NSW, Australia
    Influenza Other Respir Viruses 7:168-76. 2013
  4. doi request reprint Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors?
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, NSW, Australia
    Med Mycol 48:S37-44. 2010
  5. pmc Viral pneumonitis is increased in obese patients during the first wave of pandemic A(H1N1) 2009 virus
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia
    PLoS ONE 8:e55631. 2013
  6. pmc Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis
    Azian Harun
    Molecular Mycology Research Laboratory, Medical School Westmead Hospital, Westmead, NSW 2145, Australia
    J Clin Microbiol 49:1508-12. 2011
  7. pmc Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection
    Adrian Ong
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, New South Wales, Australia
    J Clin Microbiol 49:2067-71. 2011
  8. doi request reprint Pandemic (H1N1) 2009 influenza virus seroconversion rates in HIV-infected individuals
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    J Acquir Immune Defic Syndr 56:91-4. 2011
  9. pmc Pandemic clinical case definitions are non-specific: multiple respiratory viruses circulating in the early phases of the 2009 influenza pandemic in New South Wales, Australia
    Vigneswary Mala Ratnamohan
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    Virol J 11:113. 2014
  10. doi request reprint Pneumonia and lung infections due to emerging and unusual fungal pathogens
    Sharon C A Chen
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, Australia
    Semin Respir Crit Care Med 32:703-16. 2011

Detail Information

Publications18

  1. pmc Detection of occult Scedosporium species in respiratory tract specimens from patients with cystic fibrosis by use of selective media
    C C Blyth
    Centre of Infectious Diseases and Microbiology Laboratory Services, ICPMR, Westmead Hospital, Darcy Rd, Westmead, NSW 2145, Australia
    J Clin Microbiol 48:314-6. 2010
    ..9%) patients yielded a Scedosporium sp., most frequently Scedosporium aurantiacum (17/218). Scedosporium was recovered on SceSel+, Mycosel, and SABD from 90.6%, 50.0%, and 46.9% of the specimens tested, respectively...
  2. pmc Influenza outbreaks during World Youth Day 2008 mass gathering
    Christopher C Blyth
    Westmead Hospital, Sydney, New South Wales, Australia
    Emerg Infect Dis 16:809-15. 2010
    ..Greater flexibility by public health authorities and hospitals is required to appropriately manage and contain these outbreaks...
  3. doi request reprint The impact of bacterial and viral co-infection in severe influenza
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research ICPMR, Westmead Hospital, Sydney, NSW, Australia
    Influenza Other Respir Viruses 7:168-76. 2013
    ..Many questions remain concerning the burden, risk factors and impact of bacterial and viral co-infection in patients with pandemic influenza admitted to the intensive care unit (ICU)...
  4. doi request reprint Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors?
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, NSW, Australia
    Med Mycol 48:S37-44. 2010
    ..Studies are required to confirm independent risk factors for Scedosporium colonization and to determine its impact on lung disease...
  5. pmc Viral pneumonitis is increased in obese patients during the first wave of pandemic A(H1N1) 2009 virus
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Sydney Institute for Emerging Infections and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia
    PLoS ONE 8:e55631. 2013
    ..It is postulated that excess inflammation and cytokine production in obese patients following severe influenza infection leads to viral pneumonitis and/or acute respiratory distress syndrome...
  6. pmc Development and validation of a multiplex PCR for detection of Scedosporium spp. in respiratory tract specimens from patients with cystic fibrosis
    Azian Harun
    Molecular Mycology Research Laboratory, Medical School Westmead Hospital, Westmead, NSW 2145, Australia
    J Clin Microbiol 49:1508-12. 2011
    ..1% and 97.2%, respectively. This highly species-specific multiplex PCR assay offers a rapid and simple method of detection of the most clinically important Scedosporium species in respiratory tract specimens...
  7. pmc Fatal mycotic aneurysms due to Scedosporium and Pseudallescheria infection
    Adrian Ong
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, New South Wales, Australia
    J Clin Microbiol 49:2067-71. 2011
    ..The thoracoabdominal aorta was affected in one patient, and cerebral vessels were affected in the other. Despite voriconazole therapy and surgical resection, the patients died. Previously reported cases are reviewed...
  8. doi request reprint Pandemic (H1N1) 2009 influenza virus seroconversion rates in HIV-infected individuals
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    J Acquir Immune Defic Syndr 56:91-4. 2011
    ..Neither HIV infection, nor severe immunosuppression, was a significant risk factor for pandemic influenza during the first southern hemisphere pandemic wave...
  9. pmc Pandemic clinical case definitions are non-specific: multiple respiratory viruses circulating in the early phases of the 2009 influenza pandemic in New South Wales, Australia
    Vigneswary Mala Ratnamohan
    Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia
    Virol J 11:113. 2014
    ..During the early phases of the 2009 pandemic, subjects with influenza-like illness only had laboratory testing specific for the new A(H1N1)pdm09 virus...
  10. doi request reprint Pneumonia and lung infections due to emerging and unusual fungal pathogens
    Sharon C A Chen
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, Australia
    Semin Respir Crit Care Med 32:703-16. 2011
    ..Surgical resection of diseased tissue and support of the host immune system are often required to optimize outcomes...
  11. ncbi request reprint Enhanced diagnosis of pandemic (H1N1) 2009 influenza infection using molecular and serological testing in intensive care unit patients with suspected influenza
    Jenna M Iwasenko
    Department of Microbiology, South Eastern Area Laboratory Services, Prince of Wales Hospital, Randwick, New South Wales, Australia
    Clin Infect Dis 51:70-2. 2010
    ..These results indicate that up to one-third of pH1N1 cases may not have laboratory confirmation of infection unless serological testing is included for suspected cases...
  12. ncbi request reprint Detection of the rapid emergence of the H275Y mutation associated with oseltamivir resistance in severe pandemic influenza virus A/H1N1 09 infections
    Bin Wang
    Retroviral Genetics Laboratory, Center for Virus Research, Westmead Millennium Institute, Westmead, NSW 2145, Australia
    Antiviral Res 87:16-21. 2010
    ..In the light of emerging resistance, close monitoring and understanding of the nature and dynamics of resistance mutations in newly emerging strains should be a priority...
  13. ncbi request reprint Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections
    Christopher C Blyth
    Centre for Infectious Disease and Microbiology, ICPMR, Westmead Hospital, Darcy Road, Westmead, New South Wales, Australia, 2145
    Cochrane Database Syst Rev 2:CD006343. 2010
    ..Further comparative paediatric antifungal drug trials and epidemiological and pharmacological studies are required highlighting the differences between neonates, children and adults with invasive fungal infections...
  14. pmc Influenza outbreak during Sydney World Youth Day 2008: the utility of laboratory testing and case definitions on mass gathering outbreak containment
    Sebastiaan J van Hal
    Centre for Infectious Diseases and Microbiology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, Sydney, New South Wales, Australia
    PLoS ONE 4:e6620. 2009
    ..However, the utility of these clinical case definitions and laboratory testing in mass gathering outbreaks remains unknown...
  15. pmc Comparison of a rapid antigen test with nucleic acid testing during cocirculation of pandemic influenza A/H1N1 2009 and seasonal influenza A/H3N2
    Jen Kok
    Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales 2145, Australia
    J Clin Microbiol 48:290-1. 2010
    ..4% versus 74.2%, P < 0.001). Nucleic acid tests should be used to detect pandemic influenza virus when rapid antigen tests are negative...
  16. doi request reprint Nontuberculous mycobacterial infection in children: a prospective national study
    Christopher C Blyth
    Department of Immunology and Infectious Diseases, Sydney Children s Hospital, New South Wales, Australia
    Pediatr Infect Dis J 28:801-5. 2009
    ..The epidemiology and management of nontuberculous mycobacterial (NTM) infection in Australian children is unknown...
  17. doi request reprint Point of care testing: diagnosis outside the virology laboratory
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Sydney, NSW, Australia
    Methods Mol Biol 665:415-33. 2011
    ..The sensitivity, specificity, and turn-around time of available POCTs are included for common conditions including respiratory viral infections (e.g. influenza, RSV) and blood-borne viral infections (e.g. HIV)...
  18. doi request reprint Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients
    Christopher C Blyth
    Centre for Infectious Diseases and Microbiology, Westmead Hospital, Hawkesbury Road, Westmend, New South Wales 2145, Australia
    Pediatrics 123:1360-8. 2009
    ..The purpose of this work was to identify differences in incidence, risk factors, microbiology, treatment, and clinical outcome of candidemia in neonates, children, and adults that might impact on management...