Martin Blomberg Jensen

Summary

Publications

  1. ncbi Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Mol Cell Endocrinol 377:93-102. 2013
  2. pmc Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Neoplasia 14:952-63. 2012
  3. ncbi Non-genomic effects of vitamin D in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Steroids 77:903-9. 2012
  4. ncbi Vitamin D metabolism, sex hormones, and male reproductive function
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Reproduction 144:135-52. 2012
  5. ncbi Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
    M Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark
    Ann Oncol 19:1910-4. 2008
  6. ncbi Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Hum Reprod 26:1307-17. 2011
  7. ncbi Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
    Martin Blomberg Jensen
    University Department of Growth and Reproduction GR, Rigshospitalet Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 25:1303-11. 2010
  8. ncbi Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    Martin Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 121:376-82. 2010
  9. ncbi Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model
    Anne Jørgensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Science, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 136:238-46. 2013
  10. ncbi PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men
    Ulla Nordström Joensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Hum Reprod 28:599-608. 2013

Detail Information

Publications16

  1. ncbi Characterization of the testicular, epididymal and endocrine phenotypes in the Leuven Vdr-deficient mouse model: targeting estrogen signalling
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Mol Cell Endocrinol 377:93-102. 2013
    ..In conclusion, vitamin D seems dispensable for murine spermatogenesis and sex hormone production, but aberrant estrogen-signalling may elicit some of the VDR-mediated effects on male reproduction...
  2. pmc Vitamin D metabolism and effects on pluripotency genes and cell differentiation in testicular germ cell tumors in vitro and in vivo
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Neoplasia 14:952-63. 2012
    ....
  3. ncbi Non-genomic effects of vitamin D in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Steroids 77:903-9. 2012
    ..A functional role of the VD-mediated Ca(2+) increase was supported by showing that 1,25(OH)(2)D(3) increased sperm motility and induced the acrosome reaction in vitro...
  4. ncbi Vitamin D metabolism, sex hormones, and male reproductive function
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Reproduction 144:135-52. 2012
    ..The reviewed evidence suggests some effects of VD on estrogen and testosterone biosynthesis and implicates involvement of both systemic and local VD metabolism in the regulation of male fertility potential...
  5. ncbi Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
    M Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Blegdamsvej, Copenhagen, Denmark
    Ann Oncol 19:1910-4. 2008
    ....
  6. ncbi Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Hum Reprod 26:1307-17. 2011
    ..We investigated the role of activated VD (1,25(OH)(2)D(3)) in human spermatozoa and whether VD serum levels are associated with semen quality...
  7. ncbi Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
    Martin Blomberg Jensen
    University Department of Growth and Reproduction GR, Rigshospitalet Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Hum Reprod 25:1303-11. 2010
    ..Therefore, we performed a comprehensive analysis of the expression of VDR, VD activating (CYP2R1, CYP27A1, CYP27B1) and inactivating (CYP24A1) enzymes in the testis, epididymis, seminal vesicle (SV), prostate and spermatozoa...
  8. ncbi Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer
    Martin Blomberg Jensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 121:376-82. 2010
    ....
  9. ncbi Influence of vitamin D on cisplatin sensitivity in testicular germ cell cancer-derived cell lines and in a NTera2 xenograft model
    Anne Jørgensen
    Department of Growth and Reproduction, Rigshospitalet, Faculty of Health Science, University of Copenhagen, Denmark
    J Steroid Biochem Mol Biol 136:238-46. 2013
    ..This article is part of a Special Issue entitled 'Vitamin D Workshop'...
  10. ncbi PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men
    Ulla Nordström Joensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Hum Reprod 28:599-608. 2013
    ..Is exposure to perfluorinated compounds (PFCs) associated with testicular function (reproductive hormone levels and semen quality) in healthy men?..
  11. ncbi Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry
    Anne Jørgensen
    Department of Growth and Reproduction, University of Copenhagen, Blegdamsvej 9, Copenhagen DK 2100, Denmark
    Mol Hum Reprod 18:523-34. 2012
    ..The biological importance of the changes in expression of DMRT1 in Sertoli cells remains to be established, but it is consistent with DMRT1 reinforcing the inhibition of meiosis in the testis...
  12. ncbi Vitamin D and male reproduction
    Martin Blomberg Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Nat Rev Endocrinol 10:175-86. 2014
    ..Future studies are needed to determine when 1α,25-dihydroxyvitamin D acts in a paracrine manner and whether systemic changes, which are subject to pharmacological modulation, could influence male reproductive function. ..
  13. ncbi [Antioxidants and male subfertility--a survey of a Cochrane review]
    Tina Kold Jensen
    Klinik for Vækst og Reproduktion, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark
    Ugeskr Laeger 173:3253-5. 2011
    ..Future studies should be large, randomized placebo-controlled trials...
  14. pmc Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men
    Ulla Nordström Joensen
    Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
    Environ Health Perspect 120:1397-403. 2012
    ..In animals, some phthalates impair male reproductive development and function. Epidemiological studies have reported inconsistent evidence of associations between phthalates and markers of human testicular function...
  15. ncbi High dietary intake of saturated fat is associated with reduced semen quality among 701 young Danish men from the general population
    Tina K Jensen
    University Department of Growth and Reproduction, Rigshospitalet, Copenhagen, Denmark
    Am J Clin Nutr 97:411-8. 2013
    ..Saturated fat intake has been associated with both cardiovascular disease and cancer risk, and a newly published study found an association between saturated fat intake and a lower sperm concentration in infertile men...
  16. ncbi Regional differences and temporal trends in male reproductive health disorders: semen quality may be a sensitive marker of environmental exposures
    Loa Nordkap
    University Department of Growth and Reproduction, Rigshospitalet, Section 5064, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Mol Cell Endocrinol 355:221-30. 2012
    ....