Effect of GB virus C viremia on HIV acquisition and HIV set-pointGregory P Bisson
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
AIDS 19:1910-2. 2005
..32; 95% confidence interval 0.6-2.6). Pre-existing GBV-C viremia at the time of HIV acquisition was also not associated with lower plasma HIV-RNA levels...
- Diagnostic accuracy of CD4 cell count increase for virologic response after initiating highly active antiretroviral therapy
Gregory P Bisson
Department of Medicine, Division of Infectious Diseases, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104 6021, USA
AIDS 20:1613-9. 2006
..To derive and internally validate a clinical prediction rule for virologic response based on CD4 cell count increase after initiation of HAART in a resource-limited setting...
Antiretroviral failure despite high levels of adherence: discordant adherence-response relationship in BotswanaGregory P Bisson
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Acquir Immune Defic Syndr 49:107-10. 2008
..Although adherence to antiretroviral therapy may be higher in sub-Saharan Africa, knowledge regarding the magnitude of adherence needed to maintain virological suppression in this setting is limited...
Overestimates of survival after HAART: implications for global scale-up effortsGregory P Bisson
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
PLoS ONE 3:e1725. 2008
..Determining definitive outcomes of these lost patients, and the effects of losses to follow-up on estimates of survival and risk factors for death after HAART, are key to monitoring the effectiveness of global HAART scale-up efforts...
- Pharmacy refill adherence compared with CD4 count changes for monitoring HIV-infected adults on antiretroviral therapy
Gregory P Bisson
Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
PLoS Med 5:e109. 2008
....
- The use of HAART is associated with decreased risk of death during initial treatment of cryptococcal meningitis in adults in Botswana
Gregory P Bisson
Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
J Acquir Immune Defic Syndr 49:227-9. 2008
..The objective of this study was to evaluate outcomes among adults with a first episode of cryptococcal meningitis (CM), comparing those on highly active antiretroviral therapy (HAART) with those not on HAART...
- Out-of-pocket costs of HAART limit HIV treatment responses in Botswana's private sector
Gregory P Bisson
Division of Infectious Disease, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
AIDS 20:1333-6. 2006
..001]. HAART costs should be minimized as scale-up efforts in sub-Saharan Africa progress...
- Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis
Gregory P Bisson
Division of Infectious Diseases, Department of Medicine, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
J Bacteriol 194:6441-52. 2012
..These findings may assist in developing novel methods to diagnose and treat drug-resistant M. tuberculosis infections...
- Early mortality and AIDS progression despite high initial antiretroviral therapy adherence and virologic suppression in Botswana
Katherine T Steele
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
PLoS ONE 6:e20010. 2011
..We sought to determine the relationship between very early ART adherence and early adverse outcomes in HIV-infected adults in Botswana...
- Isoniazid-resistant tuberculous meningitis, United States, 1993-2005
Christopher Vinnard
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Emerg Infect Dis 17:539-42. 2011
..Foreign-born patients were more likely to be infected with an isoniazid-resistant strain...
- Early versus delayed antiretroviral therapy and cerebrospinal fluid fungal clearance in adults with HIV and cryptococcal meningitis
Gregory P Bisson
Department of Medicine, Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, and The Children s Hospital of Philadelphia, Philadelphia, PA 19104 6021, USA
Clin Infect Dis 56:1165-73. 2013
..This study tested the hypothesis that initiation of ART during initial treatment of HIV/CM would improve CSF clearance of C. neoformans...
- HIV infection and glycemic response to newly initiated diabetic medical therapy
Jennifer H Han
Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, 3rd Floor, Silverstein Building, Ste E, Philadelphia, PA 19104, USA
AIDS 26:2087-95. 2012
..The objective of this study was to compare the effectiveness of initial diabetic medical therapy in patients with and without HIV infection...
- Cryptococcus and lymphocytic meningitis in Botswana
Gregory P Bisson
Infectious Diseases Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
S Afr Med J 98:724-5. 2008
..Moreover, almost 70% of CSF samples with significant lymphocytosis did not yield a pathogen, suggesting that many causes of lymphocytic meningitis go undiagnosed...
- Lost but not forgotten--the economics of improving patient retention in AIDS treatment programs
Gregory P Bisson
University of Pennsylvania School of Medicine, Department of Medicine, Division of Infectious Diseases, Philadelphia, Pennsylvania, USA
PLoS Med 6:e1000174. 2009
..Gregory Bisson and Jeffrey Stringer discuss the implications of a new study showing how loss to follow-up affects the effectiveness of a public sector HIV program in Côte d'Ivoire...
- A simple novel method for determining mortality rates in HIV treatment programs worldwide
Gregory P Bisson
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
PLoS Med 8:e1000392. 2011
....
- Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections
Zahoor Ahmad
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Antimicrob Agents Chemother 55:1527-32. 2011
..Clinical studies are warranted to investigate the sterilizing activity and tolerability of higher doses of pyrazinamide in combination tuberculosis regimens...
- Isoniazid resistance and death in patients with tuberculous meningitis: retrospective cohort study
Christopher Vinnard
Department of Medicine, Division of Infectious Diseases, University of Pennsylvania School of Medicine, 502 Johnson Pavilion, 3610 Hamilton Walk, Philadelphia, PA 19104, USA
BMJ 341:c4451. 2010
..To determine whether initial isoniazid resistance is associated with death during the treatment of tuberculous meningitis...
