Gerald F Bills

Summary

Publications

  1. pmc Hypoxylon pulicicidum sp. nov. (Ascomycota, Xylariales), a pantropical insecticide-producing endophyte
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain
    PLoS ONE 7:e46687. 2012
  2. doi request reprint The "FERMEX" method for metabolite-enriched fungal extracts
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Armilla, Granada, Spain
    Methods Mol Biol 944:79-96. 2012
  3. doi request reprint Kabatiella bupleuri sp. nov. (Dothideales), a pleomorphic epiphyte and endophyte of the Mediterranean plant Bupleurum gibraltarium (Apiaceae)
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Granada, Spain
    Mycologia 104:962-73. 2012
  4. ncbi request reprint Discovery of the parnafungins, antifungal metabolites that inhibit mRNA polyadenylation, from the Fusarium larvarum complex and other Hypocrealean fungi
    Gerald F Bills
    Centro de Investigación Básica, Merck, SHARP and DOHME de ESPANA S A, Josefa Valcárcel 38, Madrid, E 28027, Spain
    Mycologia 101:449-72. 2009
  5. doi request reprint Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica
    Ignacio Pérez-Victoria
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 3, Parque Tecnológico de Ciencias de la Salud, E 18100 Armilla, Granada, Spain
    J Nat Prod 75:1210-4. 2012
  6. doi request reprint Distribution of the antifungal agents sordarins across filamentous fungi
    Francisca Vicente
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, Josefa Valcarcel, 38, 28027 Madrid, Spain
    Mycol Res 113:754-70. 2009
  7. ncbi request reprint High-throughput culturing of fungi from plant litter by a dilution-to-extinction technique
    Javier Collado
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, S A, Madrid, Spain
    FEMS Microbiol Ecol 60:521-33. 2007
  8. ncbi request reprint Studies on Morinia: recognition of Morinia longiappendiculata sp. nov. as a new endophytic fungus, and a new circumscription of Morinia pestalozzioides
    Javier Collado
    Centro de Investigación Básica, Merck Research Laboratories, Merck, Sharp and Dohme de España, josefa Valcárcel 38 E 28027 Madrid, Espana
    Mycologia 98:616-27. 2006
  9. doi request reprint Manipulating filamentous fungus chemical phenotypes by growth on nutritional arrays
    José R Tormo
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Armilla, Granada, Spain
    Methods Mol Biol 944:59-78. 2012
  10. ncbi request reprint Conspecificity of the cerulenin and helvolic acid producing 'Cephalosporium caerulens', and the hypocrealean fungus Sarocladium oryzae
    Gerald F Bills
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, Josefa Valcárcel 38, ES 28027 Madrid, Spain
    Mycol Res 108:1291-300. 2004

Collaborators

Detail Information

Publications12

  1. pmc Hypoxylon pulicicidum sp. nov. (Ascomycota, Xylariales), a pantropical insecticide-producing endophyte
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain
    PLoS ONE 7:e46687. 2012
    ....
  2. doi request reprint The "FERMEX" method for metabolite-enriched fungal extracts
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Armilla, Granada, Spain
    Methods Mol Biol 944:79-96. 2012
    ..The necessary equipment, protocol, and media recipes are described along with examples of bioactive fungal metabolites produced in this system...
  3. doi request reprint Kabatiella bupleuri sp. nov. (Dothideales), a pleomorphic epiphyte and endophyte of the Mediterranean plant Bupleurum gibraltarium (Apiaceae)
    Gerald F Bills
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Granada, Spain
    Mycologia 104:962-73. 2012
    ..This new species is a sister species of the morphologically similar clover pathogen, K. caulivora...
  4. ncbi request reprint Discovery of the parnafungins, antifungal metabolites that inhibit mRNA polyadenylation, from the Fusarium larvarum complex and other Hypocrealean fungi
    Gerald F Bills
    Centro de Investigación Básica, Merck, SHARP and DOHME de ESPANA S A, Josefa Valcárcel 38, Madrid, E 28027, Spain
    Mycologia 101:449-72. 2009
    ..rubrum represents a species distinct from var. larvarum. Finally we report that two other species from the Hypocreales, Trichonectria rectipila and Cladobotryum pinarense, are able to produce parnafungins and their open-ring forms...
  5. doi request reprint Isolation and structural elucidation of cyclic tetrapeptides from Onychocola sclerotica
    Ignacio Pérez-Victoria
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avenida del Conocimiento 3, Parque Tecnológico de Ciencias de la Salud, E 18100 Armilla, Granada, Spain
    J Nat Prod 75:1210-4. 2012
    ..2) but did not inhibit the hERG potassium channel and were not cytotoxic. These peptides are the first secondary metabolites ever reported from fungi of the order Arachnomycetales...
  6. doi request reprint Distribution of the antifungal agents sordarins across filamentous fungi
    Francisca Vicente
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, Josefa Valcarcel, 38, 28027 Madrid, Spain
    Mycol Res 113:754-70. 2009
    ..e., Sordariales, Eurotiales, and Microascales), suggesting that the production of sordarin is a trait more frequently associated to members of the Xylariales than to any other fungal order...
  7. ncbi request reprint High-throughput culturing of fungi from plant litter by a dilution-to-extinction technique
    Javier Collado
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, S A, Madrid, Spain
    FEMS Microbiol Ecol 60:521-33. 2007
    ..Intercolony interactions are reduced, permitting longer incubation times, and colony initiation and recovery improved. Effort to evaluate and recover colonies from fungal isolation plates was substantially reduced...
  8. ncbi request reprint Studies on Morinia: recognition of Morinia longiappendiculata sp. nov. as a new endophytic fungus, and a new circumscription of Morinia pestalozzioides
    Javier Collado
    Centro de Investigación Básica, Merck Research Laboratories, Merck, Sharp and Dohme de España, josefa Valcárcel 38 E 28027 Madrid, Espana
    Mycologia 98:616-27. 2006
    ..A lectotype and epitype are designated for the species. A study of bioactive metabolites revealed that M. pestalozzioides cultures produced moriniafungin, a novel sordarin analog with potent antifungal activity...
  9. doi request reprint Manipulating filamentous fungus chemical phenotypes by growth on nutritional arrays
    José R Tormo
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Armilla, Granada, Spain
    Methods Mol Biol 944:59-78. 2012
    ..The necessary equipment, custom tools, and protocols to grow fungi in nutritional arrays are described along with examples of bioactive secondary metabolites discovered using this system...
  10. ncbi request reprint Conspecificity of the cerulenin and helvolic acid producing 'Cephalosporium caerulens', and the hypocrealean fungus Sarocladium oryzae
    Gerald F Bills
    Centro de Investigación Básica, Merck Sharp and Dohme de Espana, Josefa Valcárcel 38, ES 28027 Madrid, Spain
    Mycol Res 108:1291-300. 2004
    ..At least two of the isolates of S. oryzae produced titres of cerulenin and helvolic acid similar to those of KF-140. This finding demonstrates that manufacture of cerulenin need not be limited to the original strain...
  11. pmc Prescreening bacterial colonies for bioactive molecules with Janus plates, a SBS standard double-faced microbial culturing system
    Marina Sanchez-Hidalgo
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Parque Tecnológico de Ciencias de la Salud, Armilla, Granada, Spain
    Antonie Van Leeuwenhoek 102:361-74. 2012
    ..We also envisage the method's utility for functional prescreening colonies of clones from genomic and metagenomic libraries or improved strains originating from mutagenized cells...
  12. doi request reprint Chemical and physical modulation of antibiotic activity in emericella species
    Mercedes de la Cruz
    Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Avda del Conocimiento 3, Parque Tecnológico de Ciencias de la Salud, ES 18100 Armilla, Granada
    Chem Biodivers 9:1095-113. 2012
    ..Several species are reported for the first time to produce echinocandin B. A new echinocandin analog, echinocandin E, was identified from E. quadrilineata...