Postoperative complications associated with transfusion of platelets and plasma in cardiac surgeryYavuz M Bilgin
Department of Immunohematology and Blood Transfusion and Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
Transfusion 51:2603-10. 2011
..Whether platelet (PLT) and/or plasma transfusions are a marker for more concomitant RBC transfusions or are independently associated with complications after cardiac surgery is unknown...
Is increased mortality associated with post-operative infections after leukocytes containing red blood cell transfusions in cardiac surgery? An extended analysisY M Bilgin
Department of Hematology, Academical Medical Center, Amsterdam, The Netherlands
Transfus Med 17:304-11. 2007
..This re-analysis shows that transfusion of leukocytes containing RBCs during cardiac surgery may be associated with more infections with fatal outcome. This should be confirmed in a larger extended analysis or a prospective study...
Treatment of severe psychosis due to ectopic Cushing's syndromeY M Bilgin
Department of Internal Medicine, IJsselland Hospital, 2900 AR Capelle aan den IJssel, The Netherlands
J Endocrinol Invest 30:776-9. 2007
..This case report demonstrates the efficacy of a treatment of mifepristone with etomidate in a patient with an ectopic ACTH-producing Cushing's syndrome...
Mannose-binding lectin is involved in multiple organ dysfunction syndrome after cardiac surgery: effects of blood transfusionsYavuz M Bilgin
Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
Transfusion 48:601-8. 2008
..Preoperative transfusions of allogeneic white blood cells (WBCs) contribute to infectious and inflammatory complications. This study investigates the role of MBL in relation to blood transfusions and complications after cardiac surgery...
Transfusion-related immunomodulation: a second hit in an inflammatory cascade?Y M Bilgin
Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
Vox Sang 95:261-71. 2008
..We suggest that leucocyte-containing transfusions during and after cardiac surgery add a second insult to the cardiopulmonary bypass procedure-induced systemic inflammatory response...
Effects of allogeneic leukocytes in blood transfusions during cardiac surgery on inflammatory mediators and postoperative complicationsYavuz M Bilgin
Sanquin Blood Bank Southwest Region, Leiden, Netherlands
Crit Care Med 38:546-52. 2010
..To investigate whether the higher prevalence of postoperative complications in cardiac surgery after transfusion of leukocyte-containing red blood cells can be related to inflammatory mediators...
Double-blind, randomized controlled trial on the effect of leukocyte-depleted erythrocyte transfusions in cardiac valve surgeryY M Bilgin
Department of Hematology, Academic Medical Center, Amsterdam, The Netherlands
Circulation 109:2755-60. 2004
..We found in a previous study a decrease in mortality rates and number of infections in a subgroup of more heavily transfused patients...