Tihana Bicanic

Summary

Publications

  1. pmc Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients
    Guanggan Hu
    The Michael Smith Laboratories, Department of Microbiology and Immunology, and Faculty of Land and Food Systems, University of British Columbia, Vancouver, B C V6T 1Z4, Canada
    BMC Genomics 12:526. 2011
  2. doi request reprint High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 47:123-30. 2008
  3. doi request reprint Immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis: a prospective study
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 51:130-4. 2009
  4. doi request reprint Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    AIDS 23:701-6. 2009
  5. pmc Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial
    Joseph N Jarvis
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    AIDS 26:1105-13. 2012
  6. ncbi request reprint Fungal burden, early fungicidal activity, and outcome in cryptococcal meningitis in antiretroviral-naive or antiretroviral-experienced patients treated with amphotericin B or fluconazole
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa
    Clin Infect Dis 45:76-80. 2007
  7. doi request reprint Comparison of the early fungicidal activity of high-dose fluconazole, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for the treatment of HIV-associated cryptococcal meningitis
    Angela Loyse
    Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    Clin Infect Dis 54:121-8. 2012
  8. ncbi request reprint Symptomatic relapse of HIV-associated cryptococcal meningitis after initial fluconazole monotherapy: the role of fluconazole resistance and immune reconstitution
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 43:1069-73. 2006
  9. ncbi request reprint Lumbar drainage for control of raised cerebrospinal fluid pressure in cryptococcal meningitis: case report and review
    Karen F Macsween
    Division of Infectious Diseases, Department of Cellular and Molecular Medicine, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    J Infect 51:e221-4. 2005
  10. ncbi request reprint Antiretroviral roll-out, antifungal roll-back: access to treatment for cryptococcal meningitis
    Tihana Bicanic
    Lancet Infect Dis 5:530-1. 2005

Collaborators

Detail Information

Publications11

  1. pmc Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients
    Guanggan Hu
    The Michael Smith Laboratories, Department of Microbiology and Immunology, and Faculty of Land and Food Systems, University of British Columbia, Vancouver, B C V6T 1Z4, Canada
    BMC Genomics 12:526. 2011
    ..Here, we examined the genome plasticity and phenotypes of monosomic and disomic strains, and compared their virulence in a mouse model of cryptococcosis..
  2. doi request reprint High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 47:123-30. 2008
    ..A dosage range for AmB of 0.7-1 mg/kg per day is noted in current guidelines, but there are no data comparing 0.7 mg/kg per day with 1 mg/kg per day...
  3. doi request reprint Immune reconstitution inflammatory syndrome in HIV-associated cryptococcal meningitis: a prospective study
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    J Acquir Immune Defic Syndr 51:130-4. 2009
    ..Prospective data on incidence, characteristics, and risk factors for cryptococcal meningitis immune reconstitution inflammatory syndrome (CM-IRIS) are lacking...
  4. doi request reprint Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    AIDS 23:701-6. 2009
    ....
  5. pmc Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial
    Joseph N Jarvis
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    AIDS 26:1105-13. 2012
    ..We performed a randomized controlled trial to determine whether addition of IFNγ to standard therapy increased the rate of clearance of cryptococcal infection in HIV-associated cryptococcal meningitis...
  6. ncbi request reprint Fungal burden, early fungicidal activity, and outcome in cryptococcal meningitis in antiretroviral-naive or antiretroviral-experienced patients treated with amphotericin B or fluconazole
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa
    Clin Infect Dis 45:76-80. 2007
    ....
  7. doi request reprint Comparison of the early fungicidal activity of high-dose fluconazole, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for the treatment of HIV-associated cryptococcal meningitis
    Angela Loyse
    Infectious Diseases Unit, GF Jooste Hospital, Cape Town, South Africa
    Clin Infect Dis 54:121-8. 2012
    ..Alternative, more widely available, and/or more effective antifungal combination treatment regimens are urgently needed...
  8. ncbi request reprint Symptomatic relapse of HIV-associated cryptococcal meningitis after initial fluconazole monotherapy: the role of fluconazole resistance and immune reconstitution
    Tihana Bicanic
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Clin Infect Dis 43:1069-73. 2006
    ..Therefore, we conducted a study to assess the contribution of these factors to CM relapse in this context...
  9. ncbi request reprint Lumbar drainage for control of raised cerebrospinal fluid pressure in cryptococcal meningitis: case report and review
    Karen F Macsween
    Division of Infectious Diseases, Department of Cellular and Molecular Medicine, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    J Infect 51:e221-4. 2005
    ..The advantages and necessary precautions with this approach are reviewed, and alternative protocols for the use of lumbar drains discussed...
  10. ncbi request reprint Antiretroviral roll-out, antifungal roll-back: access to treatment for cryptococcal meningitis
    Tihana Bicanic
    Lancet Infect Dis 5:530-1. 2005
  11. ncbi request reprint Cryptococcal meningitis
    Tihana Bicanic
    Division of Infectious Diseases, Department of Cellular and Molecular Medicine, St George s Hospital Medical School, London, UK
    Br Med Bull 72:99-118. 2004
    ..Studies are needed to define more fungicidal drug regimens and to improve the treatment of raised intracranial pressure...