Maitree Bhattacharyya


Affiliation: University of Calcutta
Location: Kolkata, India
Protein structure and function

Oxidative stress and Diabetes Mellitus

Hemoglobin and Red blood Cell

Chronic Arsenic toxicity, role of nutrition and oxidative stress

Microbial ecology, bacterial diversity

Leghemoglobin--biochemical and biophysical characterisation
1.Mandal B, Mukherjee D,Bhattacharyya M.Structure function alteration of hemoglobin in Arsenocosis patients : A probable pathway to exert toxicity .Journal of Applied Toxicology .2010.In Press

2.Chakraborty A ,Chowdhury S,Bhattacharyya M.EFFECT OF METFORMIN ON OXIDATIVE STRESS, NITROSATIVE STRESS AND INFLAMMATORY BIOMARKERS IN TYPE 2 DIABETES PATIENTS.Diabetes research and clinical practice.2010.In press.

3.Mukherjee S, Chakraborty A, Bahttacharyya M.Cervical Cancer Induced Structural Disorganization of Human Erythrocyte Membrane.IJBPS.2010

4.Manna S,Chaudhuri K, Bhattacharyya S,Bhattacharyya M.Dynamics of Sundarban estuarine ecosystem: eutrophication induced threat to mangroves. Saline Systems,2010,6:8.

5.Adak S, Sengupta S , Chowdhury S and Bhattacharyya M.Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population.Diabetes and Vascular Disease Research. 2010; 7; 63

6.Adak S, Chowdhury S and Bhattacharyya M. Dynamic and electrokinetic behavior of erythrocyte membrane in diabetes mellitus and diabetic cardiovascular disease Biochimica et Biophysica Acta (BBA) - General Subjects. (2008) Biochimica et Biophysica Acta ,1780, 108-115

7.Arindam Saha, Sangeeta Adak, Subhankar Chowdhury, Maitree Bhattacharyya (2005), Enhanced Oxygen releasing capacity and Oxidative stress in Diabetes Mellitus and Diabetes Mellitus Associated Cardiovascular Disease: A comparative study—Clinica Chimica Acta,( Elsevier) 361,141-149 (Sangeeta and Arindam have equal contribution in the work)

8.Dibyendu Chakraborty & Maitree Bhattacharyya (2001), Antioxidant defence status of Red Blood cell in ß-thalassemia patient, Clinica Cheimica Acta (Elsevier), 305,123-129

9.Dibyendu Chakraborty & Maitree Bhattacharyya (2000), Deferiprone (L1) induced conformation change of Hemoglobin : A fluorescence and CD spectroscopic study, Molecular and Cellular Biochemistry , 204, 17-20

10.Atanu K. Khatua & Maitree Bhattacharyya (2001), NADPH-induced oxidative damage of rat liver microsomes: Protective role of chlorpromazine and trifluoperazine, Polish Journal of Pharmacology, 53, 629-634


  1. request reprint
    Khatua A, Bhattacharyya M. NADPH-induced oxidative damage of rat liver microsomes: protective role of chlorpromazine and trifluoperazine. Pol J Pharmacol. 2001;53:629-34 pubmed
    ..Due to the stronger antioxidant property of TFZ, it can be prescribed as a better therapeutic agent, which plays a protective role for the cellular system. ..
  2. request reprint
    Saha A, Adak S, Chowdhury S, Bhattacharyya M. Enhanced oxygen releasing capacity and oxidative stress in diabetes mellitus and diabetes mellitus-associated cardiovascular disease: a comparative study. Clin Chim Acta. 2005;361:141-9 pubmed
    ..Hyperglycemia-induced oxidative stress was responsible to affect the thermal stability and oxygen releasing capacity of hemoglobin and the effect is more pronounced in diabetes-associated cardiovascular disease. ..
  3. request reprint
    Adak S, Chowdhury S, Bhattacharyya M. Dynamic and electrokinetic behavior of erythrocyte membrane in diabetes mellitus and diabetic cardiovascular disease. Biochim Biophys Acta. 2008;1780:108-15 pubmed
    ..44+/-1.34 mV, and -22.21+/-1.21 mV respectively indicating a gradual lowering of zeta potential when erythrocyte membrane undergoes progressive changes - from simple agglomeration to fluid gel formation - and finally to a rigid gel. ..
  4. Adak S, Sengupta S, Chowdhury S, Bhattacharyya M. Co-existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population. Diab Vasc Dis Res. 2010;7:63-8 pubmed publisher
    ..In our population a novel 111/112-haplotype combination created by the CAPN10 UCSNP-43, -19 and -63 was associated with risk of T2DM. Haplotypes 112 and 121 with opposite genetic influences also co-exist in our population. ..
  5. Manna S, Chaudhuri K, Bhattacharyya S, Bhattacharyya M. Dynamics of Sundarban estuarine ecosystem: eutrophication induced threat to mangroves. Saline Systems. 2010;6:8 pubmed publisher
    ..This study indicates that ecosystem dynamics of the world heritage site Sundarban may facilitate bioinvasion putting a question mark on the sustainability of mangroves. ..
  6. Dutta S, Bhattacharyya M, Sengupta K. Implications and Assessment of the Elastic Behavior of Lamins in Laminopathies. Cells. 2016;5: pubmed
    ..We also present an up-to-date understanding of the methods used to determine laminar elasticity both at the bulk and single molecule level. ..
  7. Pattanayak R, Basak P, Sen S, Bhattacharyya M. Interaction of KRAS G-quadruplex with natural polyphenols: A spectroscopic analysis with molecular modeling. Int J Biol Macromol. 2016;89:228-37 pubmed publisher
    ..We have developed a general model to estimate the influence of the ligands towards stabilizing the G-quadruplex subsequently characterizing the binding profile to enlighten prospective therapeutics. ..
  8. Ghoshal K, Das S, Aich K, Goswami S, Chowdhury S, Bhattacharyya M. A novel sensor to estimate the prevalence of hypochlorous (HOCl) toxicity in individuals with type 2 diabetes and dyslipidemia. Clin Chim Acta. 2016;458:144-53 pubmed publisher
    ..0001) resulting in higher HOCl content. The hyperglycemic and hyperlipidemic challenges together enhance the production of HOCl and the fluoroprobe RHQ may be used as a novel diagnostic marker to evaluate the extent of this toxicity. ..
  9. Kar T, Basak P, Ghosh R, Bhattacharyya M. Protective effects of curcumin against gamma ray induced conformational change of human serum albumin. Int J Biol Macromol. 2017;99:600-607 pubmed publisher
    ..A model for curcumin based protection has been proposed utilizing ThT assay. ..

Detail Information


  1. Das A, Basak P, Pattanayak R, Kar T, Majumder R, Pal D, et al. Trehalose induced structural modulation of Bovine Serum Albumin at ambient temperature. Int J Biol Macromol. 2017;105:645-655 pubmed publisher
    ..The results are in unison with the preferential exclusion and vitrification models to explain protein stabilization by trehalose and also points at the structure-function trade-off of proteins in presence of trehalose. ..
  2. Ghoshal K, Chakraborty S, Das C, Chattopadhyay S, Chowdhury S, Bhattacharyya M. Dielectric properties of plasma membrane: A signature for dyslipidemia in diabetes mellitus. Arch Biochem Biophys. 2017;635:27-36 pubmed publisher
    ..Therefore, dielectric parameters of PBMCs in diabetic-dyslipidemic challenges may led to interesting correlation opening the possibility of identifying crucial signature biomarkers. ..
  3. Nag S, Pramanik A, Chattopadhyay D, Bhattacharyya M. Green-fabrication of gold nanomaterials using Staphylococcus warneri from Sundarbans estuary: an effective recyclable nanocatalyst for degrading nitro aromatic pollutants. Environ Sci Pollut Res Int. 2018;25:2331-2349 pubmed publisher
    ..This green technology for bioremediation of toxic nitro aromatic pollutants is safe and economically beneficial to challenge the development and sustainability issue. ..