- Pre-transplant analysis of accommodation in donor pigsWilliam E Beschorner
Ximerex, Inc, Omaha, NE 68116 2461, USA
Xenotransplantation 10:66-71. 2003..Acute vascular rejection was not observed in the heterotopic heart transplants from six donors with PBL accommodation. Only one incident of moderate diffuse cellular rejection (grade 3) was observed...
- Heart xenograft survival with chimeric pig donors and modest immune suppressionWilliam E Beschorner
Department of Surgery, Transplantation Section, University Nebraska Medical Center, Omaha, NE 68198 3285, USA
Ann Surg 237:265-72. 2003..The clinical use of pig organ xenografts is currently precluded by severe acute rejection, which resists standard immune suppression...
- Human/Pig Model of Hepatitis C Virus for New VaccinesWilliam Beschorner; Fiscal Year: 2005..A large animal immune compentent model of HCV will lead to a better understanding of the pathogenesis of hepatitis C virus and to more effective vaccines and immune therapy. ..
- Heart Xenotransplantation with Chimeric Donor PigsWilliam Beschorner; Fiscal Year: 2006..Follow up studies would establish the relative contribution of tissue accommodation and specific immune tolerance to the prolongation of heart xenograft survival. ..
- Islet Transplantation with Chimeric Donor PigsWilliam Beschorner; Fiscal Year: 2007..These will permit earlier detection of rejection or graft failure, and establish the safety of xenotransplantation with regards to risk of zoonotie or opportunistic infections. ..